Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

  • Stereotactic Body Radiotherapy as a Curative Treatment for De Novo Mucosal Carcinoma of the Head and Neck: A Feasible Alternative Option for Fragile Patients with Small Lesion: A Systematic Review † 
    Strojan, Primož; Kokalj, Marko; Plavc, Gaber; Ng, Sweet Ping; Nuyts, Sandra; Chiesa-Estomba, Carlos M.; Eisbruch, Avraham; de Bree, Remco; Chow, James C.H.; Mäkitie, Antti A.; Lopez, Fernando; Saba, Nabil F.; Ferlito, Alfio (Multidisciplinary Digital Publishing Institute (MDPI), 2024-06)
    Stereotactic body radiotherapy (SBRT) is characterized by a high dose per fraction, well-defined small targets, superior dose conformity, and a steep off-target dose gradient. A literature search was conducted to examine ...
  • Very long-chain acyl-coenzyme a dehydrogenase deficiency and perioperative management in adult patients 
    Welsink-Karssies, M. M.; Polderman, J. A.W.; Nieveen van Dijkum, E. J.; Preckel, B.; Schlack, W. S.; Visser, G.; Hollak, C. E.; Hermanides, J. (Springer, 2016)
    Surgery and anesthesia pose a threat to patients with very long-chain acyl-CoA dehydrogenase deficiency (VLCADD), because prolonged fasting, stress, and pain are known risk factors for the induction of metabolic derangement. ...
  • A framework for optimizing the acquisition protocol multishell diffusion-weighted imaging for multimodel assessment 
    Ciceri, Tommaso; De Luca, Alberto; Agarwal, Nivedita; Arrigoni, Filippo; Peruzzo, Denis (John Wiley & Sons Inc., 2024-08)
    Complementary aspects of tissue microstructure can be studied with diffusion-weighted imaging (DWI). However, there is no consensus on how to design a diffusion acquisition protocol for multiple models within a clinically ...
  • One-year outcomes in COVID-19 and non-COVID-19 intensive care unit survivors 
    Heesakkers, Hidde; van der Hoeven, Johannes G; Corsten, Stijn; Janssen, Inge; Ewalds, Esther; Simons, Koen S; de Blauw, Maaike; Rettig, Thijs C D; Jacobs, Crétien; van Santen, Susanne; Slooter, Arjen J C; van der Woude, Margaretha C E; Zegers, Marieke; van den Boogaard, Mark (Elsevier, 2024-12)
    Purpose: To determine differences in one-year multi-domain health outcomes in COVID-19 and non-COVID-19 intensive care unit (ICU) survivors. Materials and methods: Adult ICU survivors treated for COVID-19 were compared to ...
  • An ethics framework for the transition to an operational learning healthcare system 
    Hollestelle, Marieke J.; van der Graaf, Rieke; Sturkenboom, Miriam C.J.M.; van Delden, Johannes J.M. (John Wiley & Sons Inc., 2024-07)
    Introduction: While Learning Healthcare Systems (LHSs) have received increasing attention in health care and research, the amount of operational LHSs remains limited. Given the investment of resources in these projects, a ...
  • Left Ventricular Unloading in Extracorporeal Membrane Oxygenation: A Clinical Perspective Derived from Basic Cardiovascular Physiology 
    Protti, I.; van Steenwijk, M. P.J.; Meani, P.; Fresiello, L.; Meuwese, C. L.; Donker, D. W. (Springer, 2024-07)
    Purpose of Review: To present an abridged overview of the literature and pathophysiological background of adjunct interventional left ventricular unloading strategies during veno-arterial extracorporeal membrane oxygenation ...
  • Farmacokinetiek van antiretrovirale medicatie na bariatrische chirurgie: een casusbeschrijving en literatuuroverzicht 
    Favié, LMA; de Kanter, CTMM; Mudrikova, T; van Maarseveen, EM (2016-02-01)
  • HCN1 mutation spectrum: From neonatal epileptic encephalopathy to benign generalized epilepsy and beyond 
    Marini, Carla; Porro, Alessandro; Rastetter, Agnès; Dalle, Carine; Rivolta, Ilaria; Bauer, Daniel; Oegema, Renske; Nava, Caroline; Parrini, Elena; Mei, Davide; Mercer, Catherine; Dhamija, Radhika; Chambers, Chelsea; Coubes, Christine; Thévenon, Julien; Kuentz, Paul; Julia, Sophie; Pasquier, Laurent; Dubourg, Christèle; Carré, Wilfrid; Rosati, Anna; Melani, Federico; Pisano, Tiziana; Giardino, Maria; Innes, A. Micheil; Alembik, Yves; Scheidecker, Sophie; Santos, Manuela; Figueiroa, Sonia; Garrido, Cristina; Fusco, Carlo; Frattini, Daniele; Spagnoli, Carlotta; Binda, Anna; Granata, Tiziana; Ragona, Francesca; Freri, Elena; Franceschetti, Silvana; Canafoglia, Laura; Castellotti, Barbara; Gellera, Cinzia; Milanesi, Raffaella; Mancardi, Maria Margherita; Clark, Damien R.; Kok, Fernando; Helbig, Katherine L.; Ichikawa, Shoji; Sadler, Laurie; Neupauerová, Jana; Laššuthova, Petra; Štěrbová, Katalin; Laridon, Annick; Brilstra, Eva; Koeleman, Bobby; Lemke, Johannes R.; Zara, Federico; Striano, Pasquale; Soblet, Julie; Smits, Guillaume; Deconinck, Nicolas; Barbuti, Andrea; Difrancesco, Dario; Leguern, Eric; Guerrini, Renzo; Santoro, Bina; Hamacher, Kay; Thiel, Gerhard; Moroni, Anna; Difrancesco, Jacopo C.; Depienne, Christel (Oxford University Press, 2018-11-01)
    Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels control neuronal excitability and their dysfunction has been linked to epileptogenesis but few individuals with neurological disorders related to variants ...
  • The first titin (c.59926 + 1G > A) founder mutation associated with dilated cardiomyopathy 
    Hoorntje, Edgar T.; van Spaendonck-Zwarts, Karin Y.; te Rijdt, Wouter P.; Boven, Ludolf; Vink, Aryan; van der Smagt, Jasper J.; Asselbergs, Folkert W.; van Wijngaarden, Jan; Hennekam, Eric A.; Pinto, Yigal M.; Lekanne Deprez, Ronald H.; Barge-Schaapveld, Daniela Q.C.M.; Bootsma, Marianne; Regieli, Jakub; Hoedemaekers, Yvonne M.; Jongbloed, Jan D.H.; van den Berg, Maarten P.; van Tintelen, J. Peter (Oxford University Press, 2018-04)
  • Variants in members of the cadherin-catenin complex, CDH1 and CTNND1, cause blepharocheilodontic syndrome 
    Kievit, Anneke; Tessadori, Federico; Douben, Hannie; Jordens, Ingrid; Maurice, Madelon; Hoogeboom, Jeannette; Hennekam, Raoul; Nampoothiri, Sheela; Kayserili, Hülya; Castori, Marco; Whiteford, Margo; Motter, Connie; Melver, Catherine; Cunningham, Michael; Hing, Anne; Kokitsu-Nakata, Nancy M; Vendramini-Pittoli, Siulan; Richieri-Costa, Antonio; Baas, Annette F; Breugem, Corstiaan C; Duran, Karen; Massink, Maarten; Derksen, Patrick W B; van IJcken, Wilfred F J; van Unen, Leontine; Santos-Simarro, Fernando; Lapunzina, Pablo; Gil-da Silva Lopes, Vera L; Lustosa-Mendes, Elaine; Krall, Max; Slavotinek, Anne; Martinez-Glez, Victor; Bakkers, Jeroen; van Gassen, Koen L I; de Klein, Annelies; van den Boogaard, Marie-José H; van Haaften, Gijs (Springer Nature, 2018-02)
    Blepharocheilodontic syndrome (BCDS) consists of lagophthalmia, ectropion of the lower eyelids, distichiasis, euryblepharon, cleft lip/palate and dental anomalies and has autosomal dominant inheritance with variable ...
  • Prediction of the intestinal resistome by a three-dimensional structure-based method 
    Ruppé, Etienne; Ghozlane, Amine; Tap, Julien; Pons, Nicolas; Alvarez, Anne Sophie; Maziers, Nicolas; Cuesta, Trinidad; Hernando-Amado, Sara; Clares, Irene; Martínez, Jose Luís; Coque, Teresa M.; Baquero, Fernando; Lanza, Val F.; Máiz, Luis; Goulenok, Tiphaine; de Lastours, Victoire; Amor, Nawal; Fantin, Bruno; Wieder, Ingrid; Andremont, Antoine; van Schaik, Willem; Rogers, Malbert; Zhang, Xinglin; Willems, Rob J.L.; de Brevern, Alexandre G.; Batto, Jean Michel; Blottière, Hervé M.; Léonard, Pierre; Léjard, Véronique; Letur, Aline; Levenez, Florence; Weiszer, Kevin; Haimet, Florence; Doré, Joël; Kennedy, Sean P.; Ehrlich, S. Dusko (Nature Research, 2019-01-01)
    The intestinal microbiota is considered to be a major reservoir of antibiotic resistance determinants (ARDs) that could potentially be transferred to bacterial pathogens via mobile genetic elements. Yet, this assumption ...
  • Origin and clinical relevance of chromosomal aberrations other than the common trisomies detected by genome-wide NIPS: Results of the TRIDENT study 
    Van Opstal, Diane; van Maarle, Merel C; Lichtenbelt, Klaske; Weiss, Marjan M; Schuring-Blom, Heleen; Bhola, Shama L; Hoffer, Mariette J V; Huijsdens-van Amsterdam, Karin; Macville, Merryn V E; Kooper, Angelique J A; Faas, Brigitte H W; Govaerts, Lutgarde; Tan-Sindhunata, Gita M.; den Hollander, Nicolette S.; Feenstra, Ilse; Galjaard, Robert-Jan H; Oepkes, Dick; Ghesquiere, Stijn; Brouwer, Rutger W W; Beulen, Lean; Bollen, Sander; Elferink, Martin G; Straver, Roy; Henneman, Lidewij; Page-Christiaens, Godelieve C; Sistermans, Erik A (Lippincott Williams & Wilkins, 2018-05)
    PurposeNoninvasive prenatal screening (NIPS) using cell-free DNA in maternal blood is highly sensitive for detecting fetal trisomies 21, 18, and 13. Using a genome-wide approach, other chromosome anomalies can also be ...
  • The use of droplet digital PCR in liquid biopsies: A highly sensitive technique for MYD88 p.(L265P) detection in cerebrospinal fluid 
    Hiemcke-Jiwa, Laura S.; Minnema, Monique C.; Radersma-van Loon, Joyce H.; Jiwa, NM; de Boer, Mirthe; Leguit, Roos J.; de Weger, Roel A.; Huibers, Manon M.H. (John Wiley & Sons Inc., 2018-04)
    The gold standard for diagnosis of central nervous system lymphomas still regards a stereotactic brain biopsy, with the risk of major complications for the patient. As tumor cells can be detected in cerebrospinal fluid ...
  • Protein fermentation in the gut; implications for intestinal dysfunction in humans, pigs, and poultry 
    Gilbert, Myrthe S; Ijssennagger, Noortje; Kies, Arie K; van Mil, Saskia W C (American Physiological Society, 2018-08-01)
    The amount of dietary protein is associated with intestinal disease in different vertebrate species. In humans, this is exemplified by the association between high-protein intake and fermentation metabolite concentrations ...
  • Invited letter in response to "Predicted indirectly recognizable HLA epitopes (PIRCHE): Only the tip of the iceberg?" 
    Lachmann, Nils; Niemann, Matthias; Reinke, Petra; Budde, Klemens; Schmidt, Danilo; Halleck, Fabian; Pruß, Axel; Schönemann, Constanze; Spierings, Eric; Staeck, Oliver (Elsevier, 2018-02)
  • Profiling of 3696 nuclear receptor-coregulator interactions: A resource for biological and clinical discovery 
    Broekema, Marjoleine F.; Hollman, Danielle A.A.; Koppen, Arjen; Van Den Ham, Henk Jan; Melchers, Diana; Pijnenburg, Dirk; Ruijtenbeek, Rob; Van Mil, Saskia W.C.; Houtman, René; Kalkhoven, Eric (Endocrine Society, 2018-06-01)
    Nuclear receptors (NRs) are ligand-inducible transcription factors that play critical roles in metazoan development, reproduction, and physiology and therefore are implicated in a broad range of pathologies. The transcriptional ...
  • Primary murine mucosal response during cephalosporin-induced intestinal colonization by Enterococcus faecium 
    Hendrickx, Antoni P.A.; van de Kamer, Denise; Willems, Rob J.L. (John Wiley & Sons Inc., 2018-10)
    Hospitalized patients are often administered antibiotics that perturb the gastrointestinal commensal microbiota, leading to outgrowth of antibiotic-resistant bacteria, like multidrug-resistant Enterococcus faecium, subsequent ...
  • Progress and challenges of selective Farnesoid X Receptor modulation 
    Massafra, Vittoria; Pellicciari, Roberto; Gioiello, Antimo; van Mil, Saskia W C (Elsevier, 2018-11)
    Bile acids are amphipathic molecules that were previously known to serve as fat solubilizers in the intestine in postprandial conditions. In the last two decades, bile acids have been recognized as signaling molecules ...
  • Reasons for being in favour of or against genome modification: a survey of the Dutch general public 
    Hendriks, S; Giesbertz, N A A; Bredenoord, A L; Repping, S (2018-05-16)
    STUDY QUESTION: What are the general public's reasons for being in favour of or against the use of genome modification for five potential applications? SUMMARY ANSWER: Overall, 43 reasons for being in favour, 45 reasons ...
  • Results and reflections from the PROfiling Consortium on Antibody Repertoire and Effector functions in kidney transplantation: A mini-review 
    Kamburova, Elena G.; Hoitsma, Andries; Claas, Frans H.; Otten, Henny G.; On behalf of the PROCARE Consortium (Wiley-Blackwell, 2019-08-01)
    Kidney transplantation is the best treatment option for patients with end-stage renal disease (ESRD). The waiting time for a deceased donor kidney in the Netherlands is approximately 3 years. Mortality among patients on ...