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Now showing items 4161-4180 of 40729

N6-Methyladenosine Promotes TNF mRNA Degradation In CD4+ T Lymphocytes

van Vroonhoven, Ellen C N; Picavet, Lucas W; Scholman, Rianne C; Sijbers, Lyanne J P M; Kievit, Corlinda R E; van den Dungen, Noortje A M; Mokry, Michal; Evers, Anouk; Lebbink, Robert J; Mocholi, Enric; Coffer, Paul J; Calis, Jorg J A; Vastert, Sebastiaan J; van Loosdregt, Jorg (Oxford University Press, 2024-10-01)

N6-methyladenosine (m6A) is a RNA modification that can regulate post-transcriptional processes including RNA stability, translation, splicing, and nuclear export. In CD4+ lymphocytes, m6A modifications have been demonstrated ...
Neonatal ventriculomegaly: Pathophysiology and management guided with cranial ultrasonography

eurUS.brain group (Wiley-Blackwell, 2024-11)

Neonatal ventriculomegaly often, but not always, follows intraventricular haemorrhage in infants born preterm. Serial cranial ultrasonography (CUS) is a very useful tool to evaluate the mechanism behind ventricular dilatation, ...
Sinonasal mucosal melanoma in The Netherlands between 2001 and 2021: a clinical and epidemiological overview of 320 cases

Scheurleer, W F Julius; van de Velde, Lise J; Devriese, Lot A; de Ridder, Mischa; Louwman, Marieke W J; Breimer, Gerben E; de Bree, Remco; van Dijk, Boukje A C; Rijken, Johannes A (Springer-Verlag, 2024-10)

PURPOSE: Sinonasal mucosal melanoma (SNMM) is a rare malignancy, characterised by high (local) recurrence rates and poor survival. Comprehensive understanding of tumour etiology is currently lacking, which complicates ...
Student Perception of Knowledge and Skills in Pharmacology and Pharmacotherapy in a Bachelor’s Medical Curriculum

Pandit, Rahul; Poleij, Merel C S; Gerrits, Mirjam (International journal of medical education, 2023)

Background: Pharmacology and pharmacotherapy (P&PT) is a foundational subject within the medical curriculum, preparing students for safe prescribing. The characteristics of students entering medical school change with time, ...
Genome-wide Association Study of Susceptibility to Respiratory Syncytial Virus Hospitalization in Young Children <5 Years of age

Egeskov-Cavling, Amanda Marie; Van Wijhe, Maarten; Yakimov, Victor; Johannesen, Caroline Klint; Pollard, Andrew; Trebbien, Ramona; Bybjerg-Grauholm, Jonas; Fischer, Thea Kølsen; Bont, Louis; Respiratory Syncytial Virus Consortium in Europe (RESCEU) Investigators (Oxford University Press, 2024-08-15)

Background: Worldwide, respiratory syncytial virus (RSV) infections are among the most common causes of infant hospitalization. Host genetic factors influencing the risk and severity of RSV infection are not well known. ...
Role of C reactive protein and procalcitonin in the diagnosis of lower respiratory tract infection in children in the outpatient setting

Pérez-López, Andrés; Irwin, Adam; Rodrigo, Carlos; Prat-Aymerich, Cristina (BMJ Publishing Group, 2021-06-11)
Comparison of Four-Dimensional Flow MRI, Two-Dimensional Phase-Contrast MRI and Echocardiography in Transposition of the Great Arteries

Warmerdam, Evangeline G; Westenberg, Jos J M; Voskuil, Michiel; Rijnberg, Friso M; Roest, Arno A W; Lamb, Hildo J; van Wijk, Bram; Sieswerda, Gertjan T; Doevendans, Pieter A; Ter Heide, Henriette; Krings, Gregor J; Leiner, Tim; Grotenhuis, Heynric B (Springer New York, 2024)

Pulmonary artery (PA) stenosis is a common complication after the arterial switch operation (ASO) for transposition of the great arteries (TGA). Four-dimensional flow (4D flow) CMR provides the ability to quantify flow ...
Revised UNAIDS/WHO Ethical Guidance for HIV Prevention Trials

Van Der Graaf, Rieke; Reis, Andreas; Godfrey-Faussett, Peter (American Medical Association, 2021-05-04)
Moderators of exercise effects on self-reported cognitive functioning in cancer survivors: an individual participant data meta-analysis

Hiensch, Anouk E; Beckhaus, Julia; Witlox, Lenja; Monninkhof, Evelyn M; Schagen, Sanne B; van Vulpen, Jonna K; Sweegers, Maike G; Newton, Robert U; Aaronson, Neil K; Galvão, Daniel A; Steindorf, Karen; Stuiver, Martijn M; Mesters, Ilse; Knoop, Hans; Goedendorp, Martine M; Bohus, Martin; Thorsen, Lene; Schulz, Karl-Heinz; Schmidt, Martina E; Ulrich, Cornelia M; Sonke, Gabe S; van Harten, Wim H; Winters-Stone, Kerri M; Velthuis, Miranda J; Taaffe, Dennis R; van Mechelen, Willem; Kersten, Marie José; Nollet, Frans; Wiskemann, Joachim; Buffart, Laurien M; May, Anne M (Springer, 2024-10)

PURPOSE: This individual participant data meta-analysis (IPD-MA) assesses exercise effects on self-reported cognitive functioning (CF) and investigates whether effects differ by patient-, intervention-, and exercise-related ...
Comparison of clinical selection-based genetic testing with phenotype-agnostic extensive germline sequencing to diagnose genetic predisposition in children with cancer: a prospective diagnostic study

Bakhuizen, Jette J.; van Dijk, Freerk; Koudijs, Marco J.; Bladergroen, Reno S.; Bon, Sebastian B.B.; Hopman, Saskia M.J.; Kester, Lennart A.; Kranendonk, Mariëtte E.G.; Loeffen, Jan L.C.; Smetsers, Stephanie E.; Sonneveld, Edwin; Tachdjian, Melissa; de Vos-Kerkhof, Evelien; Goudie, Catherine; Merks, Johannes H.M.; Kuiper, Roland P.; Jongmans, Marjolijn C.J. (Elsevier, 2024-10)

Background: Germline data have become widely available in paediatric oncology since the introduction of paired tumour-germline sequencing. To guide best practice in cancer predisposition syndrome (CPS) diagnostics, we aimed ...
Automated peritoneal dialysis versus continuous ambulatory peritoneal dialysis for people with kidney failure

Driehuis, Esmee; Eshuis, Marga; Abrahams, Alferso; François, Karlien; Vernooij, Robin W.M. (John Wiley & Sons Inc., 2024-09-11)

Background: Peritoneal dialysis (PD) is a home-based kidney replacement therapy (KRT) performed in people with kidney failure. PD can be performed by manual filling and draining of the abdominal cavity, i.e. continuous ...
Addendum to Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury [Stem Cell Research, 4, (2010), 214-222]

Lai, Ruenn Chai; Arslan, Fatih; Lee, May May; Sze, Siu Kwan; Choo, Andre; Chen, Tian Sheng; Salto-Tellez, Manuel; Timmers, Leo; Lee, Chuen Neng; El Oakley, Reida Menshawe; Pasterkamp, Gerard; de Kleijn, Dominique P.V.; Lim, Sai Kiang (Elsevier, 2010-09)
Correction to: Use of antibiotics in the early COVID-19 pandemic in Poland, the Netherlands and Spain, from erraticism to (more) logic (European Journal of Clinical Pharmacology, (2024), 80, 10, (1581-1589), 10.1007/s00228-024-03726-1)

Opalska, Aleksandra; Gardarsdottir, Helga; Kwa, Marcel; Wójkowska-Mach, Jadwiga; Sabate, Monica; Ballarin, Maria Elena; de Groot, Mark; Leufkens, Hubert (Springer-Verlag, 2024-10)

The text should be inserted in the Acknowledgments section: Jadwiga Wójkowska-Mach was supported by a grant from the the National Centre for Research and Development through the initiative “Support for specialist hospitals ...
Streamlining the Journey of Research Into Clinical Practice: Making Your Patients and Practice Flourish Understanding and Setting Treatment Expectations for Patients With Metastatic Spine Tumors

Reynolds, Jeremy J.; Charest-Morin, Raphaële; Versteeg, Annemarie L.; Galgano, Michael; Lubelski, Daniel; Newman, W. Christopher; Patel, Shalin S.; Sullivan, Patricia L.Z.; Dea, Nicolas; Gasbarrini, Alessandro; Lazary, Aron; Rhines, Laurence D.; Sahgal, Arjun; Verlaan, Jorrit Jan; Fisher, Charles G.; Laufer, Ilya (SAGE Publications Inc., 2024-09)

Study Design: Literature review with clinical recommendation. Objective: A concise curation of the latest spine literature exploring the relationship between expectations and satisfaction for patients with metastatic spinal ...
Novel Aptamer Strategies in Combating Bacterial Infections: From Diagnostics to Therapeutics

Ye, Zijian; Chen, Huaizhi; Weinans, Harrie; van der Wal, Bart; Rios, Jaqueline Lourdes (Multidisciplinary Digital Publishing Institute, 2024-09)

Bacterial infections and antimicrobial resistance are posing substantial difficulties to the worldwide healthcare system. The constraints of conventional diagnostic and therapeutic approaches in dealing with continuously ...
Magnetic Resonance–Guided Focused Ultrasound Surgery for Gynecologic Indications

Knorren, Elisabeth R.; Nijholt, Ingrid M.; Schutte, Joke M.; Boomsma, Martijn F. (W.B. Saunders, 2024-11)
Exploring Parents' Experiences and Needs During Disclosure of a Cerebral Palsy Diagnosis of Their Young Child: A Scoping Review

van der Kemp, J; Ketelaar, M; Rentinck, I C M; Sommers-Spijkerman, M P J; Benders, M J N L; Gorter, J W (Wiley-Blackwell, 2024-11)

BACKGROUND: Parents often perceive the news that their child has cerebral palsy (CP) as overwhelming and shocking. They are at increased risk of parental stress and mental health problems, which in turn can affect the ...
Feasibility, safety and preliminary efficacy of preoperative stereotactic radiotherapy on the future pancreatic neck transection margin to reduce the risk of pancreatic fistula after high-risk pancreatoduodenectomy (FIBROPANC): protocol for a multicentre, single-arm trial

Suurmeijer, J. Annelie; Wismans, Leonoor V.; Hendriks, Tessa E.; Bruynzeel, Anna M.; Nuyttens, Joost J.; Intven, Martijn P.W.; van Driel, Lydi M.J.W.; Groot Koerkamp, Bas; Busch, Olivier R.; Stoker, Jaap J.; Verheij, Joanne; Farina, Arantza; Doukas, Michail; de Hingh, Ignace H.J.; Lips, Daan J.; van der Harst, Erwin; van Tienhoven, Geertjan; Besselink, Marc G.; van Eijck, Casper H.J.; Dutch Pancreatic Cancer Group (BMJ Publishing Group, 2024-09-24)

Introduction Postoperative pancreatic fistula (POPF) occurs in 25% of patients undergoing a high-risk pancreatoduodenectomy (PD) and is a driving cause of major morbidity, mortality, prolonged hospital stay and increased ...
Transportable, portable, wearable and (partially) implantable haemodialysis systems: comparison of technologies and readiness levels

Wieringa, Fokko P.; Bolhuis, Dian; Søndergaard, Henning; Ash, Stephen R.; Cummins, Cian; Gerritsen, Karin G.F.; Vollenbroek, Jeroen; Irmak, Tugrul (Oxford University Press, 2024-09-01)

Background: Dialysis modalities and their various treatment schedules result from complex compromises ('trade-offs') between medical, financial, technological, ergonomic, and ecological factors. This study targets summarizing ...
Sex hormone-binding globulin may explain sex differences for glucose homeostasis and incidence of type 2 diabetes: the KORA study

Raeisi-Dehkordi, Hamidreza; Amiri, Mojgan; Rathmann, Wolfgang; Zeller, Tanja; Adamski, Jerzy; Bano, Arjola; van der Schouw, Yvonne T.; Thorand, Barbara; Muka, Taulant; Nano, Jana (Springer Netherlands, 2024-08)

Research has indicated that sex hormone-binding globulin (SHBG) is associated with glucose homeostasis and may play a role in the etiology of type 2 diabetes (T2D). While it is unclear whether SHBG may mediate sex differences ...

Now showing items 4161-4180 of 40729