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  • Pre-surgical memory impairment is associated with risk of postoperative cognitive dysfunction in a large geriatric cohort 
    Granger, Kiri T; Spies, Claudia; Caswell, Sheryl; Hadzidiakos, Daniel; Speidel, Saya; Slooter, Arjen Jc; Kant, Ilse; Piper, Sophie K; van Montfort, Simone Jt; Barnett, Jennifer H; Moran, Paula M; Borchers, Friedrich (2025)
    Some patients undergoing surgical procedures display long-term post-surgery cognitive impairment (post-operative cognitive dysfunction; POCD), which may precipitate progression to dementia. We investigated whether preoperative ...
  • Failure to reintroduce home medication in critically ill patients 
    Polderman, Florens N.; Derijks, Hieronymus J.; Sikma, Maaike A.; van Marum, Rob J. (Elsevier, 2025-08)
    Purpose: Home medication is often discontinued or adjusted during hospital admission. This study aims to investigate discrepancies between home medication before admission and at ICU discharge. Materials and methods: In ...
  • The use of race and ethnicity in sickle cell disease research 
    Kidane Gebremeskel, Aida S; Rab, Minke A; van Werkhoven, Erik D; Petersen, Teun B; Cnossen, Marjon H; M'charek, Amade; Meeks, Karlijn A C; Rijneveld, Anita W (BioMed Central, 2025-03-07)
    This study explores practices surrounding the operationalization of ethno-racial categories (ERCs) as confounders in biomedical research, with a focus on sickle cell disease (SCD) as a model. ERCs, often aggregate labels ...
  • Childhood interstitial lung disease survivors in adulthood: a European collaborative study 
    Manali, Effrosyni D.; Griese, Matthias; Nathan, Nadia; Uzunhan, Yurdagül; Borie, Raphael; Michel, Katarzyna; Schwerk, Nicolaus; Fijolek, Justyna; Radzikowska, Elżbieta; Chua, Felix; Pabary, Rishi; Mogulkoc, Nesrin; McCarthy, Cormac; Kallieri, Maria; Papaioannou, Andriana I.; Kiper, Nural; Koziar Vasakova, Martina; Lacina, Ladislav; Molina-Molina, Maria; Torrent-Vernetta, Alba; Tsiligiannis, Theofanis; Karadag, Bulent; Kokosi, Maria; Renzoni, Elisabetta A.; van Moorsel, Coline H.M.; Campo, Ilaria; Bendstrup, Elisabeth; Prior, Thomas Skovhus; Prasse, Antje; Bonella, Francesco; Cottin, Vincent; Diesler, Rémi; Froidure, Antoine; Kolilekas, Lykourgos; Fotis, Lampros; Douros, Konstantinos; Kaditis, Athanasios G.; Jeny, Florence; Chauveau, Simon; Nunes, Hilario; Dahbia, Azrine; Mariani, Francesca; van der Vis, Joanne J.; Groen, Karlijn; Erdem Eralp, Ela; Gokdemir, Yasemin; Kocakaya, Derya; Olgun Yildizeli, Sehnaz; Yalçın, Ebru; Emiralioğlu, Nagehan; Nayir Buyuksahin, Halime; O'Brien, Helen; Karcıoglu, Oguz; Can, Demet; Ezircan, Alper; Kartal Ozturk, Gokcen; Ocal, Nesrin; Yuksel, Hasan; Narin Tongal, Sedef; Safrankova, Martina; Kourtesi, Katerina; Louvrier, Camille; Kannengiesser, Caroline; Fabre, Aurelie; Legendre, Marie; Crestani, Bruno; Pohunek, Petr; Bush, Andrew; Papiris, Spyros A. (European Respiratory Society, 2025-02-01)
    BACKGROUND: Interstitial lung disease is rarer in children than adults, but, with increasing diagnostic awareness, more cases are being discovered. The prognosis of childhood interstitial lung disease is often poor, but ...
  • Engineering of anticancer human immunoglobulin A equipped with albumin for enhanced plasma half-life 
    Mester, Simone; Chan, Chilam; Lustig, Marta; Foss, Stian; Jansen, J H Marco; Leangen Herigstad, Marie; Evers, Mitchell; Nilsen, Jeannette; Reiding, Karli R; A Damen, J Mirjam; Burger, Renate; Grevys, Algirdas; Dalhus, Bjørn; Valerius, Thomas; Sandlie, Inger; Leusen, Jeanette H W; Andersen, Jan Terje (National Academy of Sciences, 2025-02)
    Most therapeutic antibodies are based on immunoglobulin G (IgG) due to their potent effector functions and long plasma half-life. However, also monomeric IgA has emerged as an attractive candidate for cancer treatment as, ...
  • Development of Reliable and High-Throughput Human Biomimetic Cartilage and Bone Models to Explore Senescence and Personalized Osteoarthritis Treatment Options 
    Boone, Ilja; Houtman, Evelyn; Tuerlings, Margo; van den Berg, Jim J.; Lehmann, Johannes; de Keizer, Peter L.J.; Nelissen, Rob G.H.H.; Meulenbelt, Ingrid (John Wiley & Sons Inc., 2025-05)
    To facilitate effective preclinical testing of senescence treatments for osteoarthritis (OA), we have created reliable biomimetic and high-throughput models using aged human joint tissues. Moreover, concerns regarding ...
  • An evaluation of the coax monopole antenna as a transmit array element for head imaging at 14 T 
    Budé, Lyanne M.I.; Vat, Koen; Voogt, Ingmar J.; Zivkovic, Irena; Raaijmakers, Alexander J.E. (John Wiley & Sons Inc., 2025-06)
    Purpose: In comparison to dipole antennas, the coax monopole antenna (CMA) diminishes the possibility of cable-coil coupling. This greatly facilitates cable routing in spatially restricted environments, such as head coil ...
  • Implementation of WHO SMART Guidelines-Digital Adaptation Kits in Pathfinder Countries in Africa: Processes and Early Lessons Learned 
    Muliokela, Rosemary K.; Banda, Kuwani; Hussen, Abdulaziz Mohammed; Malumo, Sarai Bvulani; Kashoka, Andrew; Mwiche, Angel; Chiboma, Innocent; Barreix, Maria; Nyirenda, Muyereka; Sithole, Zvanaka; Ratanaprayul, Natschja; Endehabtu, Berhanu Fikadie; Telake, Hanna Abayneh; Weldeab, Adane; Probert, William J.M.; Tunçalp, Ozge; Maya, Ernest; Woldetsadik, Mulatu; Tilahun, Binyam; Guure, Chris; Senya, Kafui; Say, Lale; Tamrat, Tigest (JMIR Publications Inc., 2025-02-07)
    Background: The adoption of digital systems requires processes for quality assurance and uptake of standards to achieve universal health coverage. The World Health Organization developed the Digital Adaptation Kits (DAKs) ...
  • Does the Cortical-Depth Dependence of the Hemodynamic Response Function Differ Between Age Groups? 
    Raimondo, Luisa; Heij, Jurjen; Knapen, Tomas; Siero, Jeroen C.W.; van der Zwaag, Wietske; Dumoulin, Serge O. (Kluwer Academic/Human Sciences Press Inc., 2025-05)
    Functional magnetic resonance imaging (fMRI) is a widely used tool to investigate the functional brain responses in living humans. Valid comparisons of fMRI results depend on consistency of the blood-oxygen-level-dependent ...
  • Methicillin-resistant Staphylococcus aureus (MRSA) in men having sex with men (MSM): a systematic review 
    de Jong, G. M.; van der Boor, S. C.; van Bokhoven, C.; Bos, H.; Hoornenborg, E.; Joosten, R. E.; Notermans, D. W.; de Stoppelaar, S. F. (BioMed Central, 2025-03-02)
    Background: Outbreaks of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) have been documented at multiple sites worldwide. Several studies have reported an elevated infection rate of CA-MRSA ...
  • openSSS: an open-source implementation of scatter estimation for 3D TOF-PET 
    José Santo, Rodrigo; Salomon, André; W. A. M. de Jong, Hugo; Stute, Simon; Merlin, Thibaut; Beijst, Casper (Springer International Publishing AG, 2025-02-28)
    Background: Scatter correction is essential for quantitative and accurate time-of-flight (TOF) PET imaging. It is implemented by an accurate scatter estimation algorithm, to calculate the statistical distribution of scattered ...
  • Multi-material Volumetric Bioprinting and Plug-and-play Suspension Bath Biofabrication via Bioresin Molecular Weight Tuning and via Multiwavelength Alignment Optics 
    Ribezzi, Davide; Zegwaart, Jan Philip; Van Gansbeke, Thomas; Tejo-Otero, Aitor; Florczak, Sammy; Aerts, Joska; Delrot, Paul; Hierholzer, Andreas; Fussenegger, Martin; Malda, Jos; Olijve, Jos; Levato, Riccardo (Wiley-Blackwell, 2025-04-02)
    Volumetric Bioprinting (VBP), enables to rapidly build complex, cell-laden hydrogel constructs for tissue engineering and regenerative medicine. Light-based tomographic manufacturing enables spatial-selective polymerization ...
  • Geneesmiddelgeinduceerde QTverlenging: adviezen voor de praktijk 
    Becker, Matthijs L.; Berger, Florine A.; le Comte, Marianne; Gieling, Emilie M.; van Gorp, Freek; Joosten, Stephan; Kranenborg, Minke; van Walraven, Amanda; Heersche, Annemarie; Postema, Pieter G.; namens de KNMP-werkgroep QT-interacties (Kon. Ned. Mij. ter Bevordering der Pharmacie (KNMP), 2025-01-10)
    Many drugs are associated with QT prolongation on the electrocardiogram and may increase the risk of torsade de pointes (TdP). QT prolonging drugs are prescribed frequently, but the incidence of death due to TdP is estimated ...
  • Considerations and recommendations from the ISMRM Diffusion Study Group for preclinical diffusion MRI: Part 3—Ex vivo imaging: Data processing, comparisons with microscopy, and tractography 
    Schilling, Kurt G.; Howard, Amy F.D.; Grussu, Francesco; Ianus, Andrada; Hansen, Brian; Barrett, Rachel L.C.; Aggarwal, Manisha; Michielse, Stijn; Nasrallah, Fatima; Syeda, Warda; Wang, Nian; Veraart, Jelle; Roebroeck, Alard; Bagdasarian, Andrew F.; Eichner, Cornelius; Sepehrband, Farshid; Zimmermann, Jan; Soustelle, Lucas; Bowman, Christien; Tendler, Benjamin C.; Hertanu, Andreea; Jeurissen, Ben; Verhoye, Marleen; Frydman, Lucio; van de Looij, Yohan; Hike, David; Dunn, Jeff F.; Miller, Karla; Landman, Bennett A.; Shemesh, Noam; Anderson, Adam; McKinnon, Emilie; Farquharson, Shawna; Dell'Acqua, Flavio; Pierpaoli, Carlo; Drobnjak, Ivana; Leemans, Alexander; Harkins, Kevin D.; Descoteaux, Maxime; Xu, Duan; Huang, Hao; Santin, Mathieu D.; Grant, Samuel C.; Obenaus, Andre; Kim, Gene S.; Wu, Dan; Le Bihan, Denis; Blackband, Stephen J.; Ciobanu, Luisa; Fieremans, Els; Bai, Ruiliang; Leergaard, Trygve B.; Zhang, Jiangyang; Dyrby, Tim B.; Johnson, G. Allan; Cohen-Adad, Julien; Budde, Matthew D.; Jelescu, Ileana O. (John Wiley & Sons Inc., 2025-06)
    Preclinical diffusion MRI (dMRI) has proven value in methods development and validation, characterizing the biological basis of diffusion phenomena, and comparative anatomy. While dMRI enables in vivo non-invasive ...
  • Breukjes in het glazen plafond: toename van vrouwelijke hoogleraren in de psychiatrie 
    Koopmans, Anne; Lancee, Michelle; Rubbens-Özgen, Heval; Hillegers, Manon; Zinkstok, Janneke; Dols, Annemiek (Uitgeverij Boom, 2025-02)
    Achtergrond: Ondanks grote vooruitgang in de vrouwenemancipatie zijn vrouwen nog steeds ondervertegenwoordigd op de hoogste academische posities. Doel: In kaart brengen van 1. percentage vrouwelijke psychiater-hoogleraren ...
  • An open-label Phase 2a study to assess the safety and tolerability of trimetazidine in patients with amyotrophic lateral sclerosis 
    van Eijk, Ruben P.A.; Steyn, Frederik J.; Janse van Mantgem, Mark R.; Schmidt, Angela; Meyjes, Myrte; Allen, Sally; Daygon, Dara V.; Loeffler, Jean Philippe; Al-Chalabi, Ammar; van den Berg, Leonard H.; Henderson, Robert D.; Ngo, Shyuan T. (Oxford University Press, 2025)
    Metabolic imbalance is associated with amyotrophic lateral sclerosis progression. Impaired glucose oxidation and increased reliance on fatty acid oxidation contribute to reduced metabolic flexibility and faster disease ...
  • Building an international network of young surgeons across surgical specialties – Introducing the Young Surgeons Publications Committee 
    Bolm, Louisa; Nebbia, Martina; Stoop, Thomas F.; Goetz, Mara R.; Conradi, Lena; Raschzok, Nathanael; Jansson, Hannes; Larsson, Patrik; Gerber, Sarah; Roldàn, Jorge; Michelakos, Theodoros; ten Winkel, Meike; Kinny-Köster, Benedict; Rompen, Ingmar F.; Franklin, Oskar; Ziogas, Ioannis A.; Ishida, Hiroyuki; Khomiak, Andrii; Hashimoto, Daisuke; Groot, Vincent P.; Wu, Y. H.Andrew; Sugawara, Toshitaka; Oba, Atsushi; Maekawa, Aya; Oor, Jelmer E.; Morandi, Alessio; Stewart, David B.; Zyromski, Nicholas Joseph (Elsevier, 2025-03)
  • Follow-Up Adherence After Treatment With Curative Intent for Stage II and III Colorectal Cancer Patients 
    Boute, Tara C.; van Eekelen, Rik; Elferink, Marloes A.G.; Birgit, Lissenberg Witte; de Wilt, Johannes H.W.; Vink, Geraldine R.; Greuter, Marjolein J.E.; Coupé, Veerle M.H. (John Wiley & Sons Inc., 2025-03)
    Introduction: After colorectal cancer (CRC) treatment, patients undergo five-year follow-up involving carcinoembryonic antigen (CEA) tests, imaging, and colonoscopies. This retrospective cohort study explores adherence to ...
  • Implementing the My Positive Health dialogue tool for children with a chronic condition: barriers and facilitators 
    de Jong-Witjes, S; Berkelbach van der Sprenkel, E E; Kars, M C; Huber, M; Nijhof, S L; Nuboer, R; Broekhuijsen-van Henten, D M; Lasham, C A; van Mil, E G A H; van de Putte, E M (BioMed Central, 2025-03-05)
    BACKGROUND: The My Positive Health (MPH) dialogue tool for children was developed to aid children and teenagers in reflecting and communicating about their health from a broader perspective. This study investigates ...
  • Elkaar stimuleren in wetenschappelijk onderzoek bij de CWO 
    Donker, Gé; van de Werff, Suzanne; van Asselt, Kristel; Valk, Mark; Kerseboom, Ellen; de Kock, Kees; Oosterink, J. J.; Meijer, L. J.; Labots-Vogelesang, S. M.; Rümke-Gemmeke, M. P. (Bohn Stafleu van Loghum, 2021-08-01)
    De in 1957 opgerichte NHG-Commissie Wetenschappelijk Onderzoek (CWO) hield in haar ruim 60-jarige bestaan meer dan 600 maandelijkse bijeenkomsten. Wat droeg de commissie bij aan de ontwikkeling van de huisartsgeneeskunde, ...