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Now showing items 29461-29480 of 40729

A Randomized Multicenter Clinical Trial of Ultrathin Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) versus DSAEK

Dickman, Mor M.; Kruit, Pieter J.; Remeijer, Lies; van Rooij, Jeroen; Van der Lelij, Allegonda; Wijdh, Robert H J; van den Biggelaar, Frank J H M; Berendschot, Tos T J M; Nuijts, Rudy M M A (Elsevier, 2016-11-01)

Objective To compare visual acuity, refraction, endothelial cell density (ECD), and complications after Descemet stripping automated endothelial keratoplasty (DSAEK) and ultrathin DSAEK (UT-DSAEK). Design A multicenter, ...
Clinical and biochemical characteristics and bone mineral density of homozygous, compound heterozygous and heterozygous carriers of three novel IGFALS mutations.

Işık, E; Haliloglu, B; van Doorn, J; Demirbilek, H; Scheltinga , SA; Losekoot, M; Wit, JM (Oxford University Press, 2017-06)

Objective: Acid-labile subunit (ALS) deficiency (ACLSD), caused by homozygous or compound heterozygous IGFALS mutations, is associated with moderate short stature, delayed puberty, low serum IGF-I and ALS and extremely low ...
Cost-effectiveness of capecitabine and bevacizumab maintenance treatment after first-line induction treatment in metastatic colorectal cancer

Franken, M. D.; van Rooijen, E. M.; May, A. M.; Koffijberg, H.; van Tinteren, H.; Mol, L.; ten Tije, A. J.; Creemers, G. J.; van der Velden, A. M. T.; Tanis, B. C.; Groot, C. A. Uyl-de; Punt, C. J. A.; Koopman, M.; van Oijen, M. G. H. (Elsevier Limited, 2017-04)

Aim Capecitabine and bevacizumab (CAP-B) maintenance therapy has shown to be more effective compared with observation in metastatic colorectal cancer patients achieving stable disease or better after six cycles of first-line ...
Survival after associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) for advanced colorectal liver metastases: A case-matched comparison with palliative systemic therapy

Olthof, Pim B.; Huiskens, Joost; Wicherts, Dennis A.; Huespe, Pablo E.; Ardiles, Victoria; Robles-Campos, Ricardo; Adam, Rene; Linecker, Michael; Clavien, Pierre-Alain; Koopman, Miriam; Verhoef, Cornelis; Punt, Cornelis J. A.; van Gulik, Thomas M.; de Santibanes, Eduardo (Mosby Inc., 2017-04)

Background Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) allows the resection of colorectal liver metastases with curative intent which would otherwise be unresectable and only eligible ...
Narrow Band Imaging, Magnifying Chromoendoscopy, and Gross Morphological Features for the Optical Diagnosis of T1 Colorectal Cancer and Deep Submucosal Invasion: A Systematic Review and Meta-Analysis

Backes, Y.; Moss, A.; Reitsma, J. B.; Siersema, P. D.; Moons, L. M. G. (Wolters Kluwer Health, 2017-01)

OBJECTIVES: Optical diagnosis of T1 colorectal cancer (CRC) and T1 CRC with deep submucosal invasion is important in guiding the treatment strategy. The use of advanced imaging is not standard clinical practice in Western ...
Evaluatie van een geïndividualiseerd doseerschema voor busulfan bij kinderen die een allogene hematopoëtische stamceltransplantatie ondergaan

Van Reij, E. M.L.; Van Maarseveen, E. M.; Egberts, A. C.G.; Boelens, J. J.; Rademaker, C. M.A. (Kon. Ned. Mij. ter Bevordering der Pharmacie (KNMP), 2016-06-17)

OBJECTIVE To assess target attainment of busulfan exposure using a new model-based dosing regimen and therapeutic drug monitoring (TDM). Busulfan is an alkylating drug used in conditioning regimens for allogeneic haematopoietic ...
Prediction of complications in early-onset pre-eclampsia (PREP): Development and external multinational validation of prognostic models

Thangaratinam, Shakila; Allotey, John; Marlin, Nadine; Dodds, Julie; Cheong-See, Fiona; von Dadelszen, Peter; Ganzevoort, Wessel; Akkermans, Joost; Kerry, Sally; Mol, Ben W.; Moons, Karl G.M.; Riley, Richard D.; Khan, Khalid S. (BioMed Central Ltd., 2017-03-30)

Background: Unexpected clinical deterioration before 34 weeks gestation is an undesired course in early-onset pre-eclampsia. To safely prolong preterm gestation, accurate and timely prediction of complications is required. ...
Cardiovascular risk factors and incident albuminuria in screen-detected type 2 diabetes

Webb, D. R.; Zaccardi, F.; Davies, M. J.; Griffin, S. J.; Wareham, N. J.; Simmons, R. K.; Rutten, G. E.; Sandbaek, A.; Lauritzen, T.; Borch-Johnsen, K.; Khunti, K. (John Wiley & Sons Inc., 2017-05-01)

Background: It is unclear whether cardiovascular risk factor modification influences the development of renal disease in people with type 2 diabetes identified through screening. We determined predictors of albuminuria ...
Clinical evaluation of eight different D-dimer tests for the exclusion of deep venous thrombosis in primary care patients

Oude Elferink, Rob F M; Loot, Annemarieke E.; Van De Klashorst, Chantal G J; Hulsebos-Huygen, Marieke; Piersma-Wichers, Margriet; Oudega, Ruud (Informa Healthcare, 2015-05-01)

D-dimer tests are an essential element in the diagnostic work-up of deep venous thrombosis (DVT). However, the poor standardization amongst assays necessitates clinical validation before implementation in daily practice. ...
Music-based therapeutic interventions for people with dementia

van der Steen, Jenny T; van Soest-Poortvliet, Mirjam C; van der Wouden, Johannes C; Bruinsma, Manon S; Scholten, Rob Jpm; Vink, Annemiek C (John Wiley & Sons Inc., 2017)

BACKGROUND: Dementia is a clinical syndrome with a number of different causes which is characterised by deterioration in cognitive, behavioural, social and emotional functions. Pharmacological interventions are available ...
Dientamoebe fragilis bij kinderen: niks aan doen

van der Straten, Lieke; Bartelink, Marie Louise (Bohn Stafleu van Loghum, 2017-03-01)
En daar komt u nu mee

Broekhuizen, Lidewij (Bohn Stafleu van Loghum, 2017-04-01)
Level of Digitization in Dutch Hospitals and the Lengths of Stay of Patients with Colorectal Cancer

van Poelgeest, Rube; van Groningen, Julia T.; Daniels, John H.; Roes, Kit C.; Wiggers, Theo; Wouters, Michel W.; Schrijvers, Guus (Springer New York, 2017-05)

A substantial amount of research has been published on the association between the use of electronic medical records (EMRs) and quality outcomes in U.S. hospitals, while limited research has focused on the Western European ...
Circulating microRNAs in patients with intracranial aneurysms

Meeuwsen, John A.L.; Van't Hof, Femke N.G.; Van Rheenen, Wouter; Rinkel, Gabriel J.E.; Veldink, Jan H.; Ruigrok, Ynte M. (Public Library of Science, 2017-05-01)

Introduction: We compared circulating microRNA (miRNA) levels in plasma of patients with intracranial aneurysms (IA) to those of controls as a first step towards finding potential biomarkers for individuals at high risk ...
Pre-diagnosis insulin-like growth factor-I and risk of epithelial invasive ovarian cancer by histological subtypes: A collaborative re-analysis from the Ovarian Cancer Cohort Consortium

Ose, Jennifer; Schock, Helena; Poole, Elizabeth M; Lehtinen, Matti; Visvanathan, Kala; Helzlsouer, Kathy; Buring, Julie E; Lee, I-Min; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Trichopoulou, Antonia; Mattiello, Amalia; Onland-Moret, N Charlotte; Weiderpass, Elisabete; Sánchez, María-José; Idahl, Annika; Travis, Ruth C; Rinaldi, Sabina; Merritt, Melissa A; Wentzensen, Nicolas; Tworoger, Shelley S; Kaaks, Rudolf; Fortner, Renée T (Springer Netherlands, 2017-05)

PURPOSE: Biologic evidence suggests that the Insulin-like growth factor (IGF)-family may be involved in the etiology of epithelial invasive ovarian cancer (EOC). However, prospective studies investigating the role of IGF-I ...
Demographic, lifestyle, and other factors in relation to antimüllerian hormone levels in mostly late premenopausal women

Jung, Seungyoun; Allen, Naomi; Arslan, Alan A.; Baglietto, Laura; Brinton, Louise A.; Egleston, Brian L.; Falk, Roni; Fortner, Renée T.; Helzlsouer, Kathy J.; Idahl, Annika; Kaaks, Rudolph; Lundin, Eva; Merritt, Melissa; Onland-Moret, Charlotte; Rinaldi, Sabina; Sánchez, María José; Sieri, Sabina; Schock, Helena; Shu, Xiao Ou; Sluss, Patrick M.; Staats, Paul N.; Travis, Ruth C.; Tjønneland, Anne; Trichopoulou, Antonia; Tworoger, Shelley; Visvanathan, Kala; Krogh, Vittorio; Weiderpass, Elisabete; Zeleniuch-Jacquotte, Anne; Zheng, Wei; Dorgan, Joanne F. (Elsevier, 2017-04-01)

Objective To identify reproductive, lifestyle, hormonal, and other correlates of circulating antimüllerian hormone (AMH) concentrations in mostly late premenopausal women. Design Cross-sectional study. Setting Not applicable. ...
Association between changes in fat distribution and biomarkers for breast cancer

van Gemert, Willemijn A; Monninkhof, Evelyn M; May, Anne M; Elias, Sjoerd G; van der Palen, Job; Veldhuis, Wouter; Stapper, Maaike; Stellato, Rebecca K; Schuit, Jantine A; Peeters, Petra H (BioScientifica Ltd., 2017-06)

We assessed the associations between changes in total and abdominal fat and changes in biomarkers for breast cancer risk using data of the SHAPE-2 trial. In the SHAPE-2 trial, 243 postmenopausal overweight women were ...
Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins

van Bilsen, Jolanda H M; Sienkiewicz-Szłapka, Edyta; Lozano-Ojalvo, Daniel; Willemsen, Linette E M; Antunes, Celia M; Molina, Elena; Smit, Joost J; Wróblewska, Barbara; Wichers, Harry J; Knol, Edward F; Ladics, Gregory S; Pieters, Raymond H H; Denery-Papini, Sandra; Vissers, Yvonne M; Bavaro, Simona L; Larré, Colette; Verhoeckx, Kitty C M; Roggen, Erwin L (BioMed Central, 2017)

BACKGROUND: The introduction of whole new foods in a population may lead to sensitization and food allergy. This constitutes a potential public health problem and a challenge to risk assessors and managers as the existing ...
Wat als de zaaddonor een erfelijke ziekte heeft?

van der Smagt, J J; Govaerts, L C; Frints, S G M (Bohn Stafleu van Loghum, 2017-05-12)

There are no regulations in the Netherlands regarding the exchange of important genetic information that has become available after the birth of a child conceived with donor gametes. This may lead to difficult situations ...
Meerwaarde van observationeel onderzoek in chirurgie: Nuancering nodig van de hiërarchische structuur van studieopzetten

Beks, R B; Houwert, R M; Groenwold, R H H (Bohn Stafleu van Loghum, 2017-05-04)

The randomised placebo-controlled trial (RCT) is the gold standard for the evaluation of medical interventions. Observational studies, on the other hand, usually do not get much credit. For studies investigating surgical ...

Now showing items 29461-29480 of 40729