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UMC Repository: Recent submissions

  • 3D Hybrid Imaging for Structural and Congenital Heart Interventions in the Cath Lab 
    van den Broek, HT; van Es, R; Krings, GJ; Ruiter , Querina (M.B.); Voskuil, M; Loh, KP; Meine, M; Doevendans, PA; Chamuleau, SAJ; van Slochteren, FJ (Taylor & Francis, 2018-08)
    Hybrid imaging (HI) during cardiovascular interventions enables the peri-procedural visualization of the organs and tissues by means of integrating different imaging modalities. HI can improve the procedural efficacy and ...
  • Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis 
    Project Mine Als Sequencing Consortium, Mine Als Sequencing Consortium; Pulit, Sara L.; Dekker, Annelot M.; Al Khleifat, Ahmad; Brands, William J.; Iacoangeli, Alfredo; Kenna, Kevin P.; Kavak, Ersen; Kooyman, Maarten; McLaughlin, Russell L.; Middelkoop, Bas; Moisse, Matthieu; Schellevis, Raymond D.; Shatunov, Aleksey; Sproviero, William; Tazelaar, Gijs H.P.; van der Spek, Rick A.A.; van Doormaal, Perry T.C.; van Eijk, Kristel R.; van Vugt, Joke; Basak, A. Nazli; Blair, Ian P.; Glass, Jonathan D.; Hardiman, Orla; Hide, Winston; Landers, John E.; Mora, Jesus S.; Morrison, Karen E.; Newhouse, Stephen; Robberecht, Wim; Shaw, Christopher E.; Shaw, Pamela J.; van Damme, Philip; van Es, Michael A.; Wray, Naomi R.; Al-Chalabi, Ammar; van Den Berg, Leonard H.; Veldink, Jan H. (Springer Nature, 2018-10-01)
    The most recent genome-wide association study in amyotrophic lateral sclerosis (ALS) demonstrates a disproportionate contribution from low-frequency variants to genetic susceptibility to disease. We have therefore begun ...
  • Immune monitoring in allogeneic hematopoietic stem cell transplant recipients: a survey from the EBMT-CTIWP 
    Greco, Raffaella; Ciceri, Fabio; Noviello, Maddalena; Bondanza, Attilio; Vago, Luca; Oliveira, Giacomo; Peccatori, Jacopo; Cieri, Nicoletta; Ruggeri, Annalisa; Koehl, Ulrike; Fleischhauer, Katharina; Rocha, Vanderson; Dazzi, Francesco; van der Werf, Steffie Maria; Eikema, Dirk-Jan; Terwel, Sofie Rosanne; Kuball, Jürgen; Toubert, Antoine; Chabannon, Christian; Bonini, Chiara; EBMT Cellular Therapy and Immunobiology Working Party (CTIWP) (Springer Nature, 2018-09)
  • Phase I study of combined indomethacin and platinum-based chemotherapy to reduce platinum-induced fatty acids 
    van der Velden, Daphne L.; Cirkel, Geert A.; Houthuijzen, Julia M.; van Werkhoven, E.; Roodhart, Jeanine M.L.; Daenen, Laura G.M.; Kaing, Sovann; Gerrits, Johan; Verhoeven-Duif, Nanda M.; Grootscholten, Cecile; Boot, Henk; Sessa, Cristisiana; Bloemendal, Haiko J.; de Vos, Filip Y.; Voest, Emile E. (Springer-Verlag, 2018-05-01)
    Purpose: Chemotherapy-resistance remains a major obstacle to effective anti-cancer treatment. We previously showed that platinum analogs cause the release of two fatty acids. These platinum-induced fatty acids (PIFAs) ...
  • 2S protein Ara h 7.0201 has unique epitopes compared to other Ara h 7 isoforms and is comparable to 2S proteins Ara h 2 and 6 in basophil degranulation capacity 
    Hayen, S. M.; Ehlers, A. M.; den Hartog Jager, C. F.; Garssen, J.; Knol, E. F.; Knulst, A. C.; Suer, W.; Willemsen, L. E.M.; Otten, H. G. (Wiley-Blackwell, 2018-07)
    Background: Screening for specific IgE against 2S albumin proteins Ara h 2 and 6 has good positive predictive value in diagnosing peanut allergy. From the third 2S member Ara h 7, 3 isoforms have been identified. Their ...
  • Digital microscopy as a screening tool for the diagnosis of hereditary hemolytic anemia 
    Huisjes, R; van Solinge, W W; Levin, M D; van Wijk, R; Riedl, J A (Wiley-Blackwell, 2018-04)
    INTRODUCTION: Evaluation of red blood cell (RBC) morphology is an important first step in the differential diagnosis of hereditary hemolytic anemia. It is, however, labor intensive, expensive, and prone to subjectivity. ...
  • A validation study of the Caregiver Mastery Scale for partners of patients with acquired brain injury 
    Cox, Vincent Cm; Schepers, VPM; Ketelaar, Marjolijn; Kruithof, Willeke J; van Heugten, Caroline M.; Visser-Meily, Anne (SAGE Publications Ltd, 2018-04)
    OBJECTIVE: To validate the Caregiver Mastery Scale for partners of patients with acquired brain injury. DESIGN: The score distributions, internal consistency and convergent validity of the Caregiver Mastery Scale were ...
  • DEDUCE: A pattern matching method for automatic de-identification of Dutch medical text 
    Menger, Vincent; Scheepers, Floor; van Wijk, Lisette Maria; Spruit, Marco R (Elsevier Limited, 2018-07-01)
    In order to use medical text for research purposes, it is necessary to de-identify the text for legal and privacy reasons. We report on a pattern matching method to automatically de-identify medical text written in Dutch, ...
  • Stent placement for benign esophageal leaks, perforations, and fistulae: a clinical prediction rule for successful leakage control 
    van Halsema, Emo E; Kappelle, Wouter F W; Weusten, Bas L A M; Lindeboom, Robert; van Berge Henegouwen, Mark I; Fockens, Paul; Vleggaar, Frank P; Spaander, Manon C W; van Hooft, Jeanin E (Georg Thieme Verlag, 2018-02)
    Background and study aims Sealing esophageal leaks by stent placement allows healing in 44 % - 94 % of patients. We aimed to develop a prediction rule to predict the chance of successful stent therapy. Patients and methods In ...
  • Fluctuations between high- and low-modularity topology in time-resolved functional connectivity 
    Fukushima, Makoto; Betzel, Richard F.; He, Ye; de Reus, Marcel A; van den Heuvel, Martijn P; Zuo, Xi-Nian; Sporns, Olaf (Academic Press Inc., 2018-10-15)
    Modularity is an important topological attribute for functional brain networks. Recent human fMRI studies have reported that modularity of functional networks varies not only across individuals being related to demographics ...
  • Reduced astrocyte density underlying brain volume reduction in activity-based anorexia rats 
    Frintrop, Linda; Liesbrock, Johanna; Paulukat, Lisa; Johann, Sonja; Kas, Martien J.; Tolba, Rene; Heussen, Nicole; Neulen, Joseph; Konrad, Kerstin; Herpertz-Dahlmann, Beate; Beyer, Cordian; Seitz, Jochen (Informa Healthcare, 2018-04-03)
    Objectives: Severe grey and white matter volume reductions were found in patients with anorexia nervosa (AN) that were linked to neuropsychological deficits while their underlying pathophysiology remains unclear. For the ...
  • HEART score performance in Asian and Caucasian patients presenting to the emergency department with suspected acute coronary syndrome 
    de Hoog, Vince C.; Lim, Swee Han; Bank, Ingrid E.M.; Gijsberts, Crystel M.; Ibrahim, Irwani B.; Kuan, Win Sen; Ooi, Shirley B.S.; Chua, Terrance S.J.; Tai, E. Shyong; Gao, Fei; Pasterkamp, Gerard; den Ruijter, Hester M.; Doevendans, Pieter A.; Wildbergh, Thierry X.; Mosterd, Arend; Richards, A. Mark; de Kleijn, Dominique P.V.; Timmers, Leo (24150509, 2018-10)
    BACKGROUND: The HEART score is a simple and effective tool to predict short-term major adverse cardiovascular events in patients suspected of acute coronary syndrome. Patients are assigned to three risk categories using ...
  • First-trimester Placental Vascular Development in Multiparous Women differs from that in Nulliparous Women 
    Ballering, Gea; Leijnse, Janneke; Eijkelkamp, Niels; Peeters, Louis; de Heus, Roel (Informa Healthcare, 2018)
    Objective: Multiparas differ from nulliparas by delivering larger babies with larger placentas and by having a lower risk of developing placental syndromes. We postulate that these differences result from a different initial ...
  • Indoxyl Sulfate Stimulates Angiogenesis by Regulating Reactive Oxygen Species Production via CYP1B1 
    Pei, Jiayi; Juni, Rio; Harakalova, Magdalena; Duncker, Dirk J; Asselbergs, Folkert W; Koolwijk, Pieter; Hinsbergh, Victor van; Verhaar, Marianne C; Mokry, Michal; Cheng, Caroline (Multidisciplinary Digital Publishing Institute (MDPI), 2019-08-02)
    Indoxyl sulfate (IS) is an accumulative protein-bound uremic toxin found in patients with kidney disease. It is reported that IS impairs the vascular endothelium, but a comprehensive overview of all mechanisms active in ...
  • 2019 EACTS Expert Consensus on long-term mechanical circulatory support 
    Potapov, Evgenij V; Antonides, Christiaan; Crespo-Leiro, Maria G; Combes, Alain; Färber, Gloria; Hannan, Margaret M; Kukucka, Marian; de Jonge, Nicolaas; Loforte, Antonio; Lund, Lars H; Mohacsi, Paul; Morshuis, Michiel; Netuka, Ivan; Özbaran, Mustafa; Pappalardo, Federico; Scandroglio, Anna Mara; Schweiger, Martin; Tsui, Steven; Zimpfer, Daniel; Gustafsson, Finn (Elsevier, 2019-08-01)
    Long-term mechanical circulatory support (LT-MCS) is an important treatment modality for patients with severe heart failure. Different devices are available, and many-sometimes contradictory-observations regarding patient ...
  • Glibenclamide and HMR1098 normalize Cantú syndrome-associated gain-of-function currents 
    Houtman, Marien J C; Chen, Xingyu; Qile, Muge; Duran, Karen; van Haaften, Gijs; Stary-Weinzinger, Anna; van der Heyden, Marcel A G (Wiley-Blackwell, 2019-08-01)
    Cantú syndrome (CS) is caused by dominant gain-of-function mutation in ATP-dependent potassium channels. Cellular ATP concentrations regulate potassium current thereby coupling energy status with membrane excitability. No ...
  • Exploring the Association between Monoclonal Antibodies and Depression and Suicidal Ideation and Behavior: A VigiBase Study 
    Minnema, Lotte A; Giezen, Thijs J; Souverein, Patrick C; Egberts, Toine C G; Leufkens, Hubert G M; Gardarsdottir, Helga (Adis, 2019-07)
    INTRODUCTION: Several monoclonal antibodies (mAbs) have been linked to neuropsychiatric adverse effects in patients, including depression and suicidal ideation and behavior. OBJECTIVE: The aim of this study was to quantify ...
  • Estrogen Contributions to Microvascular Dysfunction Evolving to Heart Failure With Preserved Ejection Fraction 
    Sickinghe, Ariane A; Korporaal, Suzanne J A; den Ruijter, Hester M; Kessler, Elise L (Frontiers Media S. A., 2019-07-03)
    Heart failure with preserved ejection fraction (HFpEF) is a syndrome involving microvascular dysfunction. No treatment is available yet and as the HFpEF patient group is expanding due to the aging population, more knowledge ...
  • Social functioning and subclinical psychosis in adolescence: A longitudinal general adolescent population study 
    Heins, M.; Achterhof, R.; Collip, D.; Viechtbauer, W.; Kirtley, O. J.; Gunther, N.; van Os, J.; Feron, F.; Myin-Germeys, I (Wiley-Blackwell, 2019-09)
    Objectives: To investigate the longitudinal relationship between subclinical psychotic symptoms and social functioning in a representative general population sample of adolescents. Method: Data were derived from a routine ...
  • Development and internal validation of a multinomial NTCP model for the severity of acute dyspnea after radiotherapy for lung cancer 
    Defraene, Gilles; Schuit, Ewoud; De Ruysscher, Dirk (Elsevier Ireland Ltd, 2019-07-01)
    Background and purpose: Dyspnea evolution after radiotherapy for lung cancer is complex with potential symptom deterioration and improvement from baseline. We developed and internally validated a multinomial normal tissue ...