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TRPC3 is a major contributor to functional heterogeneity of cerebellar Purkinje cells

Wu, Bin; Blot, François Gc; Wong, Aaron Benson; Osório, Catarina; Adolfs, Youri; Pasterkamp, R. Jeroen; Hartmann, Jana; Becker, Esther Be; Boele, Henk Jan; De Zeeuw, Chris I.; Schonewille, Martijn (eLife Sciences Publications, 2019-09-01)

Despite the canonical homogeneous character of its organization, the cerebellum plays differential computational roles in distinct sensorimotor behaviors. Previously, we showed that Purkinje cell (PC) activity differs ...
Variatie in ggz-kosten en zorgbehoefte in de populatie: op weg naar evidence-based zorginkoop?

Van Os, J. (Uitgeverij Boom, 2019-01-01)

BACKGROUND Part of the quality of a mental health service is the degree in which the service can demonstrate that its output is aligned with indicators of population need. AIM To investigate to what degree small areas in ...
The Association Between Familial Risk and Brain Abnormalities Is Disease Specific: An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder

de Zwarte, Sonja M C; Brouwer, Rachel M; Agartz, Ingrid; Alda, Martin; Aleman, André; Alpert, Kathryn I; Bearden, Carrie E; Bertolino, Alessandro; Bois, Catherine; Bonvino, Aurora; Bramon, Elvira; Buimer, Elizabeth E L; Cahn, Wiepke; Cannon, Dara M; Cannon, Tyrone D; Caseras, Xavier; Castro-Fornieles, Josefina; Chen, Qiang; Chung, Yoonho; De la Serna, Elena; Di Giorgio, Annabella; Doucet, Gaelle E; Eker, Mehmet Cagdas; Erk, Susanne; Fears, Scott C; Foley, Sonya F; Frangou, Sophia; Frankland, Andrew; Fullerton, Janice M; Glahn, David C; Goghari, Vina M; Goldman, Aaron L; Gonul, Ali Saffet; Gruber, Oliver; de Haan, Lieuwe; Hajek, Tomas; Hawkins, Emma L; Heinz, Andreas; Hillegers, Manon H J; Hulshoff Pol, Hilleke; Hultman, Christina M; Ingvar, Martin; Johansson, Viktoria; Jönsson, Erik G; Kane, Fergus; Kempton, Matthew J; Koenis, Marinka M G; van Os, Jim; Kahn, René; van Haren, Neeltje E M; ENIGMA Relatives Working Group (Elsevier, 2019-10-01)

Background: Schizophrenia and bipolar disorder share genetic liability, and some structural brain abnormalities are common to both conditions. First-degree relatives of patients with schizophrenia (FDRs-SZ) show similar ...
Validation of a fast, robust, inexpensive, two-tiered neonatal screening test algorithm on dried blood spots for spinal muscular atrophy

Strunk, Annuska; Abbes, Andre; Stuitje, Antoine R.; Hettinga, Chris; Sepers, Eline M.; Snetselaar, Reinier; Schouten, Jan; Asselman, Fay Lynn; Cuppen, Inge; Lemmink, Henny; Ludo van der Pol, W.; Engel, Henk (Multidisciplinary Digital Publishing Institute (MDPI), 2019-05-15)

Spinal muscular atrophy (SMA) is one of the leading genetic causes of infant mortality with an incidence of 1:10,000. The recently-introduced antisense oligonucleotide treatment improves the outcome of this disease, in ...
Test-retest reliability of EEG network characteristics in infants

van der Velde, Bauke; Haartsen, Rianne; Kemner, Chantal (John Wiley & Sons Inc., 2019-05-01)

Introduction: Functional Electroencephalography (EEG) networks in infants have been proposed as useful biomarkers for developmental brain disorders. However, the reliability of these networks and their characteristics has ...
Validation of short instruments assessing parental and caregivers' perceptions on child health and development for personalized prevention

Doove, Bernice; Feron, Jolien; Feron, Frans; van Os, Jim; Drukker, Marjan (SAGE Publications Ltd, 2019-07)

Systematically exploring parental as well as other caregivers’ concerns is a main component in preventive child health care (PCHC) for family-centred practice and personalized health care. To facilitate communication and ...
The contribution of acute infarcts to cerebral small vessel disease progression

Ter Telgte, Annemieke; Wiegertjes, Kim; Gesierich, Benno; Marques, José P; Huebner, Mathias; de Klerk, Jabke J; Schreuder, Floris H B M; Araque Caballero, Miguel A; Kuijf, Hugo J; Norris, David G; Klijn, Catharina J M; Dichgans, Martin; Tuladhar, Anil M; Duering, Marco; de Leeuw, Frank-Erik (John Wiley & Sons Inc., 2019-10)

Objective: To determine the contribution of acute infarcts, evidenced by diffusion-weighted imaging positive (DWI+) lesions, to progression of white matter hyperintensities (WMH) and other cerebral small vessel disease ...
The RANO Leptomeningeal Metastasis Group proposal to assess response to treatment: lack of feasibility and clinical utility and a revised proposal: Lack of feasibility and clinical utility and a revised proposal

European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group (BTG) Central Nervous System (CNS) Metastases Committee and the EORTC BTG Imaging Committee (Oxford University Press, 2019-05-01)

BACKGROUND: A scorecard to evaluate magnetic resonance imaging (MRI) findings during the course of leptomeningeal metastases (LM) has been proposed by the Response Assessment in Neuro-Oncology (RANO) group. METHODS: To ...
Time-dependent effects of psychosocial stress on the contextualization of neutral memories

Sep, Milou S C; van Ast, Vanessa A; Gorter, Rosalie; Joëls, Marian; Geuze, Elbert (Elsevier Limited, 2019-10-01)

Memories about stressful experiences need to be both specific and generalizable to adequately guide future behavior. Memory strength is influenced by emotional significance, and contextualization (i.e., encoding experiences ...
Association of initiation of maintenance dialysis with functional status and caregiver burden

Goto, Namiko A.; Van Loon, Ismay N.; Boereboom, Franciscus T.J.; Emmelot-Vonk, Marielle H.; Willems, Hanna C.; Bots, Michiel L.; Gamadia, Laila E.; Van Bommel, Eric F.H.; Van De Ven, Peter J.G.; Douma, Caroline E.; Vincent, Hieronymus H.; Schrama, Yvonne C.; Lips, Joy; Hoogeveen, Ellen K.; Siezenga, Machiel A.; Abrahams, Alferso C.; Verhaar, Marianne C.; Hamaker, Marije E. (Lippincott Williams & Wilkins, 2019-07-01)

Background and objectives Little is known about the functional course after initiating dialysis in elderly patients with ESKD. The aim of this study was to assess the association of the initiation of dialysis in an elderly ...
Respiratory- and cardiac-triggered three-dimensional sheath inked rapid acquisition with refocused echoes imaging (SHINKEI) of the abdomen for magnetic resonance neurography of the celiac plexus

Ferrer, Cyril J; Bos, Clemens; Yoneyama, Masami; Obara, Makoto; Kok, Lisanne; van Leeuwen, Maarten S; Bleys, Ronald L A W; Moonen, Chrit T W; Bartels, Lambertus W (Springer Science and Business Media Deutschland GmbH, 2019-03-29)

The visualisation of the celiac plexus using respiratory- and cardiac-triggered three-dimensional (3D) sheath inked rapid acquisition with refocused echoes imaging (SHINKEI) was evaluated. After ethical approval and written ...
Childhood trauma and the role of self-blame on psychological well-being after deployment in male veterans

Dorresteijn, Sasja; Gladwin, Thomas Edward; Eekhout, Iris; Vermetten, Eric; Geuze, Elbert (Co-Action Publishing, 2019-01-01)

Background: Childhood trauma and combat-related trauma are both associated with decreased psychosocial functioning. Coping strategies play an important role in the adjustment to traumatic events. Objective: The present ...
Cross-scanner and cross-protocol diffusion MRI data harmonisation: A benchmark database and evaluation of algorithms

Tax, Chantal Mw; Grussu, Francesco; Kaden, Enrico; Ning, Lipeng; Rudrapatna, Umesh; Evans, John; St-Jean, Samuel; Leemans, Alexander; Koppers, Simon; Merhof, Dorit; Ghosh, Aurobrata; Tanno, Ryutaro; Alexander, Daniel C; Zappalà, Stefano; Charron, Cyril; Kusmia, Slawomir; Linden, David Ej; Jones, Derek K; Veraart, Jelle (Academic Press Inc., 2019-07-15)

Diffusion MRI is being used increasingly in studies of the brain and other parts of the body for its ability to provide quantitative measures that are sensitive to changes in tissue microstructure. However, inter-scanner ...
Worldwide Incidence of Aneurysmal Subarachnoid Hemorrhage According to Region, Time Period, Blood Pressure, and Smoking Prevalence in the Population: A Systematic Review and Meta-analysis

Etminan, Nima; Chang, Han Sol; Hackenberg, Katharina; De Rooij, Nicolien K.; Vergouwen, Mervyn D.I.; Rinkel, Gabriel J.E.; Algra, Ale (American Medical Association, 2019-05)

Importance: Subarachnoid hemorrhage (SAH) from ruptured intracranial aneurysms is a subset of stroke with high fatality and morbidity. Better understanding of a change in incidence over time and of factors associated with ...
MRI-based tumor inter-fraction motion statistics for rectal cancer boost radiotherapy

Kleijnen, Jean Paul J.E.; van Asselen, Bram; Van den Begin, Robbe; Intven, Martijn; Burbach, Johannes P.M.; Reerink, Onne; Philippens, Marielle E.P.; de Ridder, Mark; Lagendijk, Jan J.W.; Raaymakers, Bas W. (Informa Healthcare, 2019-02-01)

Background: In patients diagnosed with rectal cancer, dose escalation is currently being investigated in a large number of studies. Since there is little known on gross tumor volume (GTV) inter-fraction motion for rectal ...
Hypoxia potentiates monocyte-derived dendritic cells for release of tumor necrosis factor α via MAP3K8

Paardekooper, Laurent M.; Bendix, Maura B.; Ottria, Andrea; de Haer, Lieke W.; Ter Beest, Martin; Radstake, Timothy R.D.J.; Marut, Wioleta; van den Bogaart, Geert (Portland Press Ltd., 2018-12-21)

Dendritic cells (DCs) constantly sample peripheral tissues for antigens, which are subsequently ingested to derive peptides for presentation to T cells in lymph nodes. To do so, DCs have to traverse many different tissues ...
Étude observationnelle sur les tendances des valeurs du dioxyde de carbone en fin d’expiration au cours de l’anesthésie générale

Akkermans, Annemarie; van Waes, Judith A.R.; Thompson, Aleda; Shanks, Amy; Peelen, Linda M.; Aziz, Michael F.; Biggs, Daniel A.; Paganelli, William C.; Wanderer, Jonathan P.; Helsten, Daniel L.; Kheterpal, Sachin; van Klei, Wilton A.; Saager, Leif (Springer New York, 2019-02)

PURPOSE: Despite growing evidence supporting the potential benefits of higher end-tidal carbon dioxide (ETCO 2) levels in surgical patients, there is still insufficient data to formulate guidelines for ideal intraoperative ...
Limited benefit of haemoglobin glycation index as risk factor for cardiovascular disease in type 2 diabetes patients

Østergaard, H. B.; Mandrup-Poulsen, T.; Berkelmans, G. F.N.; van der Graaf, Y.; Visseren, F. L.J.; Westerink, J.; On behalf of the SMART Study Group (Elsevier Masson, 2019-06)

Background: The haemoglobin glycation index (HGI) has been proposed as a marker of interindividual differences in haemoglobin glycosylation. Previous studies have shown a relationship between high HGI and risk of cardiovascular ...
Potential acceleration performance of a 256-channel whole-brain receive array at 7 T

Hendriks, Arjan D; Luijten, Peter R; Klomp, Dennis W J; Petridou, Natalia (John Wiley & Sons Inc., 2019-03-01)

PURPOSE: Assess the potential gain in acceleration performance of a 256-channel versus 32-channel receive coil array at 7 T in combination with a 2D CAIPIRINHA sequence for 3D data sets. METHODS: A 256-channel receive setup ...
Multicentre prospective evaluation of real-time optical diagnosis of T1 colorectal cancer in large non-pedunculated colorectal polyps using narrow band imaging (the OPTICAL study)

Backes, Yara; Schwartz, Matthijs P; Ter Borg, Frank; Wolfhagen, Frank H J; Groen, John N; De Vos Tot Nederveen Cappel, Wouter H.; van Bergeijk, Jeroen D; Geesing, Joost M J; Spanier, Bernhard W M; Didden, Paul; Vleggaar, Frank P; Lacle, Miangela M; Elias, Sjoerd G; Moons, Leon M G; Dutch T1 CRC Working Group (BMJ Publishing Group, 2019-02)

Objective This study evaluated the preresection accuracy of optical diagnosis of T1 colorectal cancer (CRC) in large non-pedunculated colorectal polyps (LNPCPs). Design In this multicentre prospective study, endoscopists ...

Now showing items 23381-23400 of 40729