Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

  • The Clinical Phenotype of Vascular Cognitive Impairment in Patients with Type 2 Diabetes Mellitus 
    Groeneveld, Onno N; Moneti, Costanza; Heinen, Rutger; de Bresser, Jeroen; Kuijf, Hugo J; Exalto, Lieza G; Boomsma, Jooske M F; Kappelle, L Jaap; Barkhof, Frederik; Prins, Niels D; Scheltens, Philip; van der Flier, Wiesje M; Biessels, Geert Jan; TRACE-VCI study group (IOS Press, 2019-01-01)
    BACKGROUND: Type 2 diabetes mellitus (T2DM) increases the risk of vascular cognitive impairment (VCI). It is unknown which type of vascular lesions and co-morbid etiologies, in particular Alzheimer's disease pathology, are ...
  • Type 2 Diabetes, but Not Insulin (Analog) Treatment, Is Associated With More Advanced Stages of Breast Cancer: A National Linkage of Cancer and Pharmacy Registries 
    Overbeek, Jetty A; van Herk-Sukel, Myrthe P P; Vissers, Pauline A J; van der Heijden, Amber A W A; Bronsveld, Heleen K; Herings, Ron M C; Schmidt, Marjanka K; Nijpels, Giel (American Diabetes Association Inc., 2019-03)
    OBJECTIVE To investigate whether women with type 2 diabetes (T2D) develop a more advanced stage of breast cancer and whether treatment with insulin (analogs) is associated with specific breast cancer characteristics. ...
  • Haptic Feedback, Force Feedback, and Force-Sensing in Simulation Training for Laparoscopy: A Systematic Overview 
    Overtoom, Evelien M; Horeman, Tim; Jansen, Frank-Willem; Dankelman, Jenny; Schreuder, Henk W R (Elsevier, 2019)
    OBJECTIVES: To provide a systematic overview of the literature assessing the value of haptic and force feedback in current simulators teaching laparoscopic surgical skills. DATA SOURCES: The databases of Pubmed, Cochrane, ...
  • Risk of benign meningioma after childhood cancer in the DCOG-LATER cohort: Contributions of radiation dose, exposed cranial volume, and age 
    Kok, Judith L; Teepen, Jop C; van Leeuwen, Flora E; Tissing, Wim J E; Neggers, Sebastian J C M M; van der Pal, Helena J; Loonen, Jacqueline J; Bresters, Dorine; Versluys, Birgitta; van den Heuvel-Eibrink, Marry M; van Dulmen-den Broeder, Eline; van der Heiden-van der Loo, Margriet; Aleman, Berthe M P; Daniels, Laurien A; Haasbeek, Cornelis J A; Hoeben, Bianca; Janssens, Geert O; Maduro, John H; Oldenburger, Foppe; van Rij, Caroline; Tersteeg, Robbert J H A; Hauptmann, Michael; Kremer, Leontien C M; Ronckers, Cécile M; DCOG-LATER Study Group (Oxford University Press, 2019-03)
    Background. Pediatric cranial radiotherapy (CrRT) markedly increases risk of meningiomas. We studied meningioma risk factors with emphasis on independent and joint effects of CrRT dose, exposed cranial volume, exposure ...
  • Deep learning for detection of myocardial scar tissue: Goodbye to gadolinium? 
    Leiner, Tim (Radiological Society of North America Inc., 2019-06)
  • Intracranial Cerebrospinal Fluid Volume as a Predictor of Malignant Middle Cerebral Artery Infarction 
    Kauw, Frans; Bennink, Edwin; De Jong, Hugo W.A.M.; Kappelle, L. Jaap; Horsch, Alexander D.; Velthuis, Birgitta K.; Dankbaar, Jan W.; DUST Investigators (Lippincott Williams & Wilkins, 2019-06)
    Background and Purpose-Predicting malignant middle cerebral artery (MCA) infarction can help to identify patients who may benefit from preventive decompressive surgery. We aimed to investigate the association between the ...
  • Associations of Perioperative Variables With the 30-Day Risk of Stroke or Death in Carotid Endarterectomy for Symptomatic Carotid Stenosis 
    Knappich, Christoph; Kuehnl, Andreas; Haller, Bernhard; Salvermoser, Michael; Algra, Ale; Becquemin, Jean Pierre; Bonati, Leo H.; Bulbulia, Richard; Calvet, David; Fraedrich, Gustav; Gregson, John; Halliday, Alison; Hendrikse, Jeroen; Howard, George; Jansen, Olav; Malas, Mahmoud B.; Ringleb, Peter A.; Brown, Martin M.; Mas, Jean Louis; Brott, Thomas G.; Morris, Dylan R.; Lewis, Steff C.; Eckstein, Hans Henning (Lippincott Williams & Wilkins, 2019-12-01)
    Background and Purpose- This analysis was performed to assess the association between perioperative and clinical variables and the 30-day risk of stroke or death after carotid endarterectomy for symptomatic carotid stenosis. ...
  • Automatic extraction of the intracranial volume in fetal and neonatal MR scans using convolutional neural networks 
    Khalili, Nadieh; Turk, E.; Benders, M. J.N.L.; Moeskops, P.; Claessens, N. H.P.; de Heus, R.; Franx, A.; Wagenaar, N.; Breur, J. M.P.J.; Viergever, M. A.; Išgum, I. (Elsevier, 2019-01-01)
    MR images of infants and fetuses allow non-invasive analysis of the brain. Quantitative analysis of brain development requires automatic brain tissue segmentation that is typically preceded by segmentation of the intracranial ...
  • Complete regeneration of large bone defects in rats with commercially available fibrin loaded with BMP-2 
    Koolen, M; Longoni, A; van der Stok, J; Van der Jagt, O; Gawlitta, D; Weinans, H (Forum Multimedia Publishing LLC, 2019-12)
    This study aimed at investigating in vitro and in vivo the efficiency of commercially available fibrin as a carrier for controlled and sustained bone morphogenetic protein-2 (BMP-2) release to induce bone formation and ...
  • Heterotypic Scaffold Design Orchestrates Primary Cell Organization and Phenotypes in Cocultured Small Diameter Vascular Grafts 
    Jungst, Tomasz; Pennings, Iris; Schmitz, Michael; Rosenberg, Antoine J.W.P.; Groll, Jürgen; Gawlitta, Debby (Wiley-VCH Verlag, 2019-10-01)
    To facilitate true regeneration, a vascular graft should direct the evolution of a neovessel to obtain the function of a native vessel. For this, scaffolds have to permit the formation of an intraluminal endothelial cell ...
  • Validation of the clinical frailty score (CFS) in French language 
    Abraham, Paul; Courvoisier, Delphine S; Annweiler, Cedric; Lenoir, Cliff; Millien, Thomas; Dalmaz, Francoise; Flaatten, Hans; Moreno, Rui; Christensen, Steffen; de Lange, Dylan W; Guidet, Bertrand; Bendjelid, Karim; Walder, Bernhard; Bollen Pinto, Bernardo (BioMed Central, 2019-11-21)
    BACKGROUND: Very old critical ill patients are a rapid expanding group. To better understand the magnitude of the challenges involved in intensive care practice for an ageing population and discuss a rational allocation ...
  • Te oud voor de Intensive Care?: ACHTERGRONDEN EN UITDAGINGEN 
    Haas, Lenneke E.M.; Kerckhoffs, Monika C.; Emmelot-Vonk, Marielle H.; de Lange, Dylan W.; van Dijk, Diederik (Bohn Stafleu van Loghum, 2019-10-29)
    More and more elderly patients are being admitted to the hospital. These elderly patients represent a significant proportion of intensive care unit (ICU) admissions. Older ICU patients have a high risk of death during their ...
  • Author Correction: The challenge of mapping the human connectome based on diffusion tractography (Nature Communications, (2017), 8, 1, (1349), 10.1038/s41467-017-01285-x) 
    Maier-Hein, Klaus H.; Neher, Peter F.; Houde, Jean Christophe; Côté, Marc Alexandre; Garyfallidis, Eleftherios; Zhong, Jidan; Chamberland, Maxime; Yeh, Fang Cheng; Lin, Ying Chia; Ji, Qing; Reddick, Wilburn E.; Glass, John O.; Chen, David Qixiang; Feng, Yuanjing; Gao, Chengfeng; Wu, Ye; Ma, Jieyan; He, Renjie; Li, Qiang; Westin, Carl Fredrik; Deslauriers-Gauthier, Samuel; González, J. Omar Ocegueda; Paquette, Michael; St-Jean, Samuel; Girard, Gabriel; Rheault, François; Sidhu, Jasmeen; Tax, Chantal M.W.; Guo, Fenghua; Mesri, Hamed Y.; Dávid, Szabolcs; Froeling, Martijn; Heemskerk, Anneriet M.; Leemans, Alexander; Boré, Arnaud; Pinsard, Basile; Bedetti, Christophe; Desrosiers, Matthieu; Brambati, Simona; Doyon, Julien; Sarica, Alessia; Vasta, Roberta; Cerasa, Antonio; Quattrone, Aldo; Yeatman, Jason; Khan, Ali R.; Hodges, Wes; Alexander, Simon; Romascano, David; Barakovic, Muhamed (Nature Publishing Group, 2019-11-04)
    An amendment to this paper has been published and can be accessed via a link at the top of the paper.
  • Biospecimens and Molecular and Cellular Biomarkers in Aneurysmal Subarachnoid Hemorrhage Studies: Common Data Elements and Standard Reporting Recommendations 
    Chou, Sherry H-Y; Macdonald, R Loch; Keller, Emanuela; Unruptured Intracranial Aneurysms and SAH CDE Project Investigators (Humana Press, 2019-06)
    INTRODUCTION: Development of clinical biomarkers to guide therapy is an important unmet need in aneurysmal subarachnoid hemorrhage (SAH). A wide spectrum of plausible biomarkers has been reported for SAH, but none have ...
  • Alleviation of Tinnitus With High-Frequency Stimulation of the Dorsal Cochlear Nucleus: A Rodent Study 
    van Zwieten, Gusta; Jahanshahi, Ali; van Erp, Marlieke L.; Temel, Yasin; Stokroos, Robert J.; Janssen, Marcus L.F.; Smit, Jasper V. (SAGE Publications Inc., 2019-03-15)
    Deep brain stimulation of the central auditory pathway is emerging as a promising treatment modality for tinnitus. Within this pathway, the dorsal cochlear nucleus (DCN) plays a key role in the pathophysiology of tinnitus ...
  • Does Riluzole Influence Bone Formation?: An In Vitro Study of Human Mesenchymal Stromal Cells and Osteoblast 
    Schroeder, Gregory D.; Kepler, Christopher K.; Grad, Sibylle; Alini, Mauro; Fang, Taolin; Markova, Dessislava Z.; Koerner, John D.; Rajasekaran, Shanmuganathan; Chapman, Jens; Kandziora, Frank; Schnake, Klaus J.; Dvorak, Marcel F.; Oner, F. Cumhur; Vaccaro, Alexander R. (Lippincott Williams & Wilkins, 2019-08-15)
    STUDY DESIGN: A post-test design biological experiment. OBJECTIVE: The aim of this study was to evaluate the osteogenic effects of riluzole on human mesenchymal stromal cells and osteoblasts. SUMMARY OF BACKGROUND DATA: ...
  • Challenges in the design and regulatory approval of 3D-printed surgical implants: a two-case series 
    Willemsen, Koen; Nizak, Razmara; Noordmans, Herke Jan; Castelein, René M.; Weinans, Harrie; Kruyt, Moyo C. (Elsevier, 2019-08)
    Background: Additive manufacturing or three-dimensional (3D) printing of metal implants can provide novel solutions for difficult-to-treat conditions, yet legislation concerning patient-specific implants complicates the ...
  • Applicability of a Modified Rat Model of Acute Arthritis for Long-Term Testing of Drug Delivery Systems 
    Rudnik-Jansen, Imke; Woike, Nina; de Jong, Suzanne; Versteeg, Sabine; Kik, Marja; Emans, Pieter; Mihov, George; Thies, Jens; Eijkelkamp, Niels; Tryfonidou, Marianna; Creemers, Laura (Multidisciplinary Digital Publishing Institute, 2019-02-06)
    Episodes of inflammation and pain are predominant features of arthritic joint diseases. Drug delivery systems (DDS) could reduce inflammation and pain long-term without chances of infection upon multiple injections. To ...
  • Contrast enhanced computed tomography for real-time quantification of glycosaminoglycans in cartilage tissue engineered constructs 
    Garcia, João P; Longoni, Alessia; Gawlitta, Debby; J W P Rosenberg, Antoine; Grinstaff, Mark W; Töyräs, Juha; Weinans, Harrie; Creemers, Laura B; Pouran, Behdad (Elsevier, 2019-12)
    Tissue engineering and regenerative medicine are two therapeutic strategies to treat, and to potentially cure, diseases affecting cartilaginous tissues, such as osteoarthritis and cartilage defects. Insights into the ...
  • Planning feasibility of extremely hypofractionated prostate radiotherapy on a 1.5 T magnetic resonance imaging guided linear accelerator 
    den Hartogh, Mariska D.; de Boer, Hans C.J.; de Groot-van Breugel, Eline N.; van der Voort van Zyp, Jochem R.N.; Hes, Jochem; van der Heide, Uulke A.; Pos, Floris; Haustermans, Karin; Depuydt, Tom; Jan Smeenk, Robert; Kunze-Busch, Martina; Raaymakers, Bas W.; Kerkmeijer, Linda G.W. (Elsevier, 2019-07-01)
    Background and purpose: Recently, intermediate and high-risk prostate cancer patients have been treated in a multicenter phase II trial with extremely hypofractionated prostate radiotherapy (hypo-FLAME trial). The purpose ...