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A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention

VIP1 study group. Electronic address: hans.flaatten@uib.no (Elsevier, 2019-08)

BACKGROUND: We aimed to evaluate differences in outcome between patients admitted to intensive care unit (ICU) after elective versus acute surgery in a multinational cohort of very old patients (≥80 years; VIP). Predictors ...
Cardiac remodeling in aortic and mitral valve disease: A simulation study with clinical validation

Maksuti, Elira; Westerhof, Berend E.; Ugander, Martin; Donker, Dirk W.; Carlsson, Marcus; Broomé, Michael (American Physiological Society, 2019-05-01)

Remodeling is an important long-term determinant of cardiac function throughout the progression of heart disease. Numerous biomolecular pathways for mechanosensing and transduction are involved. However, we hypothesize ...
Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units.Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project

Bassetti, M; Scudeller, L; Giacobbe, D R; Lamoth, F; Righi, E; Zuccaro, V; Grecchi, C; Rebuffi, C; Akova, M; Alastruey-Izquierdo, A; Arıkan Akdagli, S; Azoulay, E; Blot, S; Cornely, O; Lass-Flörl, C; Koehler, P; Cuenca-Estrella, M; de Lange, D W; De Rosa, F G; De Waele, J J; Dimopoulos, G; Garnacho-Montero, J; Hoenigl, M; Kanj, S S; Maertens, J; Martin-Loeches, I; Muñoz, P; Kullberg, B J; Agvald-Ohman, C; Poulakou, G; Rello, J; Sanguinetti, M; Taccone, F S; Timsit, J-F; Torres, A; Vazquez, J A; Calandra, T; From the Study Group for Infections in Critically Ill Patients (ESGCIP) and the Fungal Infection Study Group (EFISG) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), the European Society of Intensive Care Medicine (ESICM), the European Confederation of Medical Mycology (ECMM), and the Mycoses Study Group Education and Research Consortium (MSGERC) (Wiley-Blackwell, 2019-04)

Background: The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU). ...
Cardiovascular efficacy and safety of bococizumab in high-risk patients

SPIRE Cardiovascular Outcome Investigators (Massachussetts Medical Society, 2017-04-20)

BACKGROUND Bococizumab is a humanized monoclonal antibody that inhibits proprotein convertase subtilisin- kexin type 9 (PCSK9) and reduces levels of low-density lipoprotein (LDL) cholesterol. We sought to evaluate the ...
Transceive phase mapping using the PLANET method and its application for conductivity mapping in the brain

Gavazzi, Soraya; Shcherbakova, Yulia; Bartels, Lambertus W.; Stalpers, Lukas J.A.; Lagendijk, Jan J.W.; Crezee, Hans; van den Berg, Cornelis A.T.; van Lier, Astrid L.H.M.W. (John Wiley & Sons Inc., 2020-02)

Purpose: To demonstrate feasibility of transceive phase mapping with the PLANET method and its application for conductivity reconstruction in the brain. Methods: Accuracy and precision of transceive phase (ϕ±) estimation ...
The lung is a host defense niche for immediate neutrophil-mediated vascular protection

Yipp, Bryan G.; Kim, Jung Hwan; Lima, Ronald; Zbytnuik, Lori D.; Petri, Bjӧrn; Swanlund, Nick; Ho, May; Szeto, Vivian G.; Tak, Tamar; Koenderman, Leo; Pickkers, Peter; Tool, Anton T.J.; Kuijpers, Taco W.; van den Berg, Timo K.; Looney, Mark R.; Krummel, Matthew F.; Kubes, Paul (American Association for the Advancement of Science, 2017-04-28)

Bloodstream infection is a hallmark of sepsis, a medically emergent condition requiring rapid treatment. However, up-regulation of host defense proteins through Toll-like receptors (TLRs) and nuclear factor B requires hours ...
Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions

van Galen, Karin Pm; Engelen, Eveline T; Mauser-Bunschoten, Evelien P; van Es, Robert JJ; Schutgens, Roger EG (John Wiley & Sons Inc., 2019-04-19)

BACKGROUND: Minor oral surgery or dental extractions (oral or dental procedures) are widely performed and can be complicated by hazardous oral bleeding, especially in people with an inherited bleeding disorder such as ...
MTOR inhibition by metformin impacts monosodium urate crystal-induced inflammation and cell death in gout: A prelude to a new add-on therapy?

Vazirpanah, Nadia; Ottria, Andrea; Van Der Linden, Maarten; Wichers, Catharina G.K.; Schuiveling, Mark; Van Lochem, Ellen; Phipps-Green, Amanda; Merriman, Tony; Zimmermann, Maili; Jansen, Matthijs; Radstake, Timothy R.D.J.; Broen, Jasper C.A. (Elsevier, 2019-05-01)

Objective: Gout is the most common inflammatory arthritis worldwide, and patients experience a heavy burden of cardiovascular and metabolic diseases. The inflammation is caused by the deposition of monosodium urate (MSU) ...
Clinical Outcomes After Unilateral Adrenalectomy for Primary Aldosteronism

International CONNsortium study group (American Medical Association, 2019-04)

Importance: In addition to biochemical cure, clinical benefits after surgery for primary aldosteronism depend on the magnitude of decrease in blood pressure (BP) and use of antihypertensive medications with a subsequent ...
Trends in Sentinel Lymph Node Biopsy Enactment for Cutaneous Melanoma

El Sharouni, Mary-Ann; Witkamp, Arjen J; Sigurdsson, Vigfús; van Diest, Paul J (Springer New York, 2019-05)

Background: Over recent years, sentinel lymph node biopsy (SLNB) recommendations in guidelines for cutaneous melanoma have changed considerably. We aimed to assess trends in enactment of SLNB to evaluate to what extent ...
Endoscopic scar assessment after colorectal endoscopic mucosal resection scars: when is biopsy necessary (EMR Scar Assessment Project for Endoscope (ESCAPE) trial): When is biopsy necessary (EMR Scar Assessment Project for Endoscope (ESCAPE) trial)

Kandel, Pujan; Brand, Eelco Christiaan; Pelt, Joe; Ball, Colleen T.; Chen, Wei Chung; Bouras, Ernest P.; Gomez, Victoria; Raimondo, Massimo; Woodward, Timothy A.; Wallace, Michael B. (BMJ Publishing Group, 2019-09)

OBJECTIVE: It is unclear whether endoscopic assessment of scars after colorectal endoscopic mucosal resection (EMR) has to include biopsies, even if endoscopy is negative. Vice versa, endoscopic diagnosis of recurrent ...
A clinical guideline on Dientamoeba fragilis infections

van Gestel, Rosanne Sfe; Kusters, Johannes G; Monkelbaan, Jan F (Cambridge University Press, 2019-08)

Dientamoeba fragilis (D. fragilis) is an intestinal parasite frequently detected in humans with abdominal pain and diarrhoea, but it is also commonly found in asymptomatic subjects. Hence its clinical relevance is often ...
Performance of bleeding risk scores in dialysis patients

Ocak, Gurbey; Ramspek, Chava; Rookmaaker, Maarten B; Blankestijn, Peter J; Verhaar, Marianne C; Bos, Willem Jan W; Dekker, Friedo W; van Diepen, Merel (Oxford University Press, 2019-07)

Background: Bleeding risk scores have been created to identify patients with an increased bleeding risk, which could also be useful in dialysis patients. However, the predictive performances of these bleeding risk scores ...
Adalimumab drug and antidrug antibody levels do not predict flare risk after stopping adalimumab in RA patients with low disease activity

Lamers-Karnebeek, Femke B G; Jacobs, Johannes W G; Radstake, Timothy R D J; van Riel, Piet L C M; Jansen, Tim L (Oxford University Press, 2019-03)

Objective To establish whether serum adalimumab (ADA) trough level (ADA-TL) and antidrug antibody (ADA-ab) level predict flare after stopping ADA in established RA patients with long-standing low disease activity. Methods ...
Endoscopic ultrasound measurements for detection of residual disease after neoadjuvant chemoradiotherapy for esophageal cancer

van der Bogt, Ruben D; Noordman, Bo J; Krishnadath, Kausilia K; Roumans, Carlijn A M; Schoon, Erik J; Oostenbrug, Liekele E; Siersema, Peter D; Vleggaar, Frank P; van Lanschot, J Jan B; Spaander, Manon C W (Georg Thieme Verlag, 2019-04)

BACKGROUND: Endoscopic ultrasound (EUS) measurements of residual thickness and residual area have been suggested to correlate with histopathological residual tumor after neoadjuvant chemoradiotherapy (nCRT) for esophageal ...
Sports participation and physical activity in patients with von Willebrand disease

Atiq, Ferdows; Mauser-Bunschoten, Eveline P; Eikenboom, Jeroen; van Galen, Karin P M; Meijer, Karina; de Meris, Joke; Cnossen, Marjon H; Beckers, Erick A M; Laros-van Gorkom, Britta A P; Nieuwenhuizen, Laurens; van der Bom, Johanna G; Fijnvandraat, Karin; Leebeek, Frank W G; WiN Study Group (Wiley-Blackwell, 2019-01)

INTRODUCTION: Patients with bleeding disorders may experience limitations in sports participation and physical activity. Several studies on sports participation have been performed in haemophilia patients, but studies in ...
The Prognostic Value of a Geriatric Risk Score for Older Patients with Colorectal Cancer

Souwer, E T D; Hultink, D; Bastiaannet, E; Hamaker, M E; Schiphorst, A; Pronk, A; van der Bol, J M; Steup, W H; Dekker, J W T; Portielje, J E A; van den Bos, F (Springer New York, 2019-01)

Introduction: VMS is a Dutch risk assessment tool for hospitalized older adults that includes a short evaluation of four geriatric domains: risk for delirium, risk for undernutrition, risk for physical impairments, and ...
Lysyl oxidase-like 2 is a regulator of angiogenesis through modulation of endothelial-to-mesenchymal transition

de Jong, Olivier G.; van der Waals, Lizet M.; Kools, Farah R.W.; Verhaar, Marianne C.; van Balkom, Bas W.M. (Wiley-Liss Inc., 2019-07)

Lysyl oxidase-like 2 (LOXL2) belongs to the family of lysyl oxidases, and as such promotes crosslinking of collagens and elastin by oxidative deamination of lysine residues. In endothelial cells (ECs), LOXL2 is involved ...
Increased mortality and hospital readmission risk in patients with dementia and a history of cardiovascular disease: results from a nationwide registry linkage study

van de Vorst, Irene E; Vaartjes, Ilonca; Bots, Michiel L; Koek, Huiberdina L (John Wiley & Sons Inc., 2019-03)

Objective: To evaluate the impact of cardiovascular disease (CVD) on mortality and readmission risk in patients with dementia. Methods: Prospective hospital-based cohort of 59 194 patients with dementia admitted to hospital ...
Precurved non-tunnelled catheters for haemodialysis are comparable in terms of infections and malfunction as compared to tunnelled catheters: A retrospective cohort study

van Oevelen, Mathijs; Abrahams, Alferso C; Weijmer, Marcel C; Nagtegaal, Tjerko; Dekker, Friedo W; Rotmans, Joris I; Meijvis, Sabine Ca; DUCATHO study group (Wichtig Publishing, 2019-05-01)

BACKGROUND:: The main limitations of central venous catheters for haemodialysis access are infections and catheter malfunction. Our objective was to assess whether precurved non-tunnelled central venous catheters are ...

Now showing items 23261-23280 of 40729