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UMC Repository: Recent submissions

  • Muti-shell Diffusion MRI Harmonisation and Enhancement Challenge (MUSHAC): Progress and Results 
    Ning, Lipeng; Bonet-Carne, Elisenda; Grussu, Francesco; Sepehrband, Farshid; Kaden, Enrico; Veraart, Jelle; Blumberg, Stefano B.; Khoo, Can Son; Palombo, Marco; Coll-Font, Jaume; Scherrer, Benoit; Warfield, Simon K.; Karayumak, Suheyla Cetin; Rathi, Yogesh; Koppers, Simon; Weninger, Leon; Ebert, Julia; Merhof, Dorit; Moyer, Daniel; Pietsch, Maximilian; Christiaens, Daan; Teixeira, Rui; Tournier, Jacques Donald; Zhylka, Andrey; Pluim, Josien; Parker, Greg; Rudrapatna, Umesh; Evans, John; Charron, Cyril; Jones, Derek K.; Tax, Chantal W.M. (Springer Heidelberg, 2019-01-01)
    We present a summary of competition results in the multi-shell diffusion MRI harmonisation and enhancement challenge (MUSHAC). MUSHAC is an open competition intended to stimulate the development of computational methods ...
  • Variation in the initial assessment and investigation for ovarian cancer in symptomatic women: a systematic review of international guidelines 
    Funston, Garth; Van Melle, Marije; Baun, Marie-Louise Ladegaard; Jensen, Henry; Helsper, Charles; Emery, Jon; Crosbie, Emma J.; Thompson, Matthew; Hamilton, Willie; Walter, Fiona M. (BioMed Central, 2019-11-01)
    Background: Women with ovarian cancer can present with a variety of symptoms and signs, and an increasing range of tests are available for their investigation. A number of international guidelines provide advice for the ...
  • Associations of preconception Body Mass Index in women with PCOS and BMI and blood pressure of their offspring 
    Gunning, M N; van Rijn, B B; Bekker, M N; de Wilde, M A; Eijkemans, M J C; Fauser, B C J M (Informa Healthcare, 2019-08-03)
    Women with polycystic ovary syndrome (PCOS) have unfavorable metabolic profiles. Their offspring may be affected by such risks. The objective of the current study was to disclose associations between preconception health ...
  • Nasal Mesenchymal Stem Cell Treatment for the Repair of Chemotherapy-Induced Neurotoxicities: Let the Trojan Horse In! 
    Boukelmoune, Nabila (Utrecht University, 2020-02-11)
    In this thesis, we show for the first time that nasal administration of mesenchymal stem cells (MSC) promotes recovery from chemotherapy-induced cognitive impairment and chemotherapy-induced peripheral neuropathy (CIPN), ...
  • The diagnostic value of nerve ultrasound in inflammatory neuropathies 
    Herraets, Ingrid (Utrecht University, 2020-02-10)
    Distinction of chronic inflammatory neuropathies (CIN) from the more common axonal neuropathies or motor neuron disease is important since treatment can improve outcome. Nerve conduction studies (NCS) play a key role in ...
  • Enhancing hepatitis C care engagement in the Netherlands: The road to micro-elimination 
    Kracht, Patricia (Utrecht University, 2020-02-06)
    In chapter 2, it was demonstrated that in 2016 several second-generation ribavirin-free DAA regimens achieved viral eradication in ≥95% in different type of patients other than those with prior NS5A-inhibitor exposure or ...
  • A prelude to cleavage: Orchestrating cytokinesis onset in mammalian cells 
    Adriaans, Ingrid (Utrecht University, 2020-02-06)
    The molecular mechanisms underlying cytokinesis appear complex and involve redundancy at various levels. Signals from the anaphase spindle define where and when cytokinesis is initiated but the biochemical nature of these ...
  • AR101: eindelijk een therapie voor pinda-allergie? 
    Knol, E (Bohn Stafleu van Loghum, 2019-05-01)
    AR101: therapy for peanut allergy finally in view? Worldwide, the incidence of peanut allergy is increasing. Spontaneous tolerance only occurs in a small percentage of children who are allergic to peanuts. To date, no ...
  • TOETVA: Schildklierchirurgie zonder blijvend litteken 
    Vriens, Menno R.; Borel Rinkes, Inne H.M. (Bohn Stafleu van Loghum, 2019-03-14)
    Transoral endoscopic thyroidectomy using a vestibular approach (TOETVA) is the first thyroid surgery that leaves no permanent visible external scar. 3 scopes are placed via the mouth, passing the front of the teeth. The ...
  • Robotgeassisteerde transaxillaire schildklieroperatie: 5 jaar later 
    Vriens, Menno R.; Postma, Emily L.; Borel Rinkes, Inne H.M. (Bohn Stafleu van Loghum, 2019-03-14)
    Five years ago, robot-assisted transaxillary thyroidectomy (RATT) was introduced in the Netherlands. The major advantage of this technique, when compared to the conventional approach, is the prevention of a potentially ...
  • Cyclin F-dependent degradation of E2F7 is critical for DNA repair and G2-phase progression 
    Yuan, Ruixue; Liu, Qingwu; Segeren, Hendrika A; Yuniati, Laurensia; Guardavaccaro, Daniele; Lebbink, Robert J; Westendorp, Bart; de Bruin, Alain (Springer Science and Business Media Deutschland GmbH, 2019-10-15)
    E2F7 and E2F8 act as tumor suppressors via transcriptional repression of genes involved in S-phase entry and progression. Previously, we demonstrated that these atypical E2Fs are degraded by APC/CCdh1 during G1 phase of ...
  • Polygenic Susceptibility of Aortic Aneurysms Associates to the Diameter of the Aneurysm Sac: the Aneurysm-Express Biobank Cohort 
    van Laarhoven, Constance J.H.C.M.; van Setten, Jessica; van Herwaarden, Joost A.; Pasterkamp, Gerard; de Kleijn, Dominique P.V.; de Borst, Gert J.; van der Laan, Sander W. (Nature Publishing Group, 2019-12-27)
    Recent genome-wide association studies (GWAS) have discovered ten genetic risk variants for abdominal aortic aneurysms (AAA). To what extent these genetic variants contribute to the pathology of aneurysms is yet unknown. ...
  • Sitting in patients with spinal muscular atrophy type 1 treated with nusinersen 
    SMA-Registry Study Group (Wiley-Blackwell, 2020-03)
    Aim: To determine factors associated with acquisition of a sitting position in patients with spinal muscular atrophy type 1 (SMA1) treated with nusinersen. Method: Using data from the registry of patients with SMA1 treated ...
  • Effectiviteit van zelfmanagementondersteuning bij diabetes 
    Vos, Rimke; van Heusden, Lisa; Eikelenboom, Natalie; Rutten, Guy (Bohn Stafleu van Loghum, 2019-11-01)
  • Amerikaanse richtlijn voor geriatrische oncologie 
    Portielje, Johanneke E A; Hamaker, Marije E; Maas, Huub A A M; van Leeuwen, Barbara L; van den Bos, Frederiek (Bohn Stafleu van Loghum, 2019-07-29)
    American guideline for geriatric oncology; applicable to Dutch clinical practice? The American Society of Clinical Oncology (ASCO) has recently issued a guideline for geriatric oncology that provides guidance regarding the ...
  • Amisulpride, een ‘one-of-a-kind’ antipsychoticum: Effectief bij de behandeling van een eerste psychose 
    Luykx, Jurjen J.; Van De Kraats, Gerben; Van Ojen, Rob (Bohn Stafleu van Loghum, 2019-01-01)
    In this commentary we discuss the findings of the recently published OPTiMiSE trial. In terms of design, important advantages of the trial are the naturalistic, open label set-up that allowed the authors to assess the ...
  • Farmacotherapeutische overwegingen bij eerste psychose — Een samenvatting van de OPTiMiSE-studie 
    Sommer, Iris E.; Rossum, Inge Winter van; Somers, Metten; Kahn, Rene S. (Bohn Stafleu van Loghum, 2019-01-01)
    Doel Hoewel antipsychotica veel gebruikt worden bij de behandeling van patiënten met een eerste psychose, is over de optimale toepassing van deze middelen veel onduidelijkheid. In deze studie onderzochten wij een algoritme ...
  • Mechanical methods for induction of labour 
    de Vaan, Marieke Dt; Ten Eikelder, Mieke Lg; Jozwiak, Marta; Palmer, Kirsten R; Davies-Tuck, Miranda; Bloemenkamp, Kitty Wm; Mol, Ben Willem J; Boulvain, Michel (John Wiley and Sons Ltd, 2019)
    BACKGROUND: Mechanical methods were the first methods developed to ripen the cervix and induce labour. During recent decades they have been substituted by pharmacological methods. Potential advantages of mechanical methods, ...
  • Signal Change in the Mammillary Bodies after Perinatal Asphyxia 
    Molavi, M; Vann, S D; de Vries, L S; Groenendaal, F; Lequin, M (American Society of Neuroradiology, 2019-11)
    BACKGROUND AND PURPOSE: Research into memory deficits associated with hypoxic-ischemic encephalopathy has typically focused on the hippocampus, but there is emerging evidence that the medial diencephalon may also be ...
  • The Effect of Metabolic Syndrome on the Occurrence of Restenosis After Carotid Endarterectomy 
    Wallis de Vries, Bastiaan M.; Timmerman, Nathalie; van Laarhoven, Constance J.H.C.M.; Visser, Linda; Pol, Robert A.; El Moumni, Mostafa; Pasterkamp, Gerard; de Borst, Gert J.; Zeebregts, Clark J. (W.B. Saunders Ltd, 2019-12)
    Objectives: The metabolic syndrome (MetS) is a cluster of risk factors for cardiovascular disease. The effect of MetS on clinical outcome in patients with cerebrovascular disease remains largely unknown because conflicting ...