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UMC Repository: Recent submissions

  • Clinical significance of auditory hallucinations in youth: Comparison between a general population and a help-seeking sample 
    Maijer, Kim; Steenhuis, Laura A.; Lotgering, Rosa; Palmen, Saskia J.M.C.; Sommer, Iris E.C.; Bartels-Velthuis, Agna A. (Elsevier, 2019-02)
  • Objective and Subjective Improvement of Cognition After Discontinuing Efavirenz in Asymptomatic Patients: A Randomized Controlled Trial 
    Hakkers, C S; Arends, J E; van den Berk, G E; Ensing, M H M; Hooijenga, I; Vink, M; van Zandvoort, M J E; Hoepelman, A I M (Lippincott Williams & Wilkins, 2019-01-01)
    Background:Efavirenz is well known for its clinical cognitive side effects. Even asymptomatic patients who switch for other reasons than neurocognitive complaints have reported a subjective improvement in cognitive functioning ...
  • Long-term course of difficulty in participation of individuals with cerebral palsy aged 16 to 34 years: a prospective cohort study 
    van Gorp, Marloes; Van Wely, Leontien; Dallmeijer, Annet J; de Groot, Vincent; Ketelaar, Marjolijn; Roebroeck, Marij E; Perrin-Decade study group (Wiley-Blackwell, 2019-02)
    AIM: To determine the long-term course of difficulty in participation of individuals with cerebral palsy (CP) without intellectual disability between 16 years and 34 years of age. METHOD: One hundred and fifty-one individuals ...
  • The landscape of epilepsy-related GATOR1 variants 
    Baldassari, Sara; Picard, Fabienne; Verbeek, Nienke E.; van Kempen, Marjan; Brilstra, Eva H.; Lesca, Gaetan; Conti, Valerio; Guerrini, Renzo; Bisulli, Francesca; Licchetta, Laura; Pippucci, Tommaso; Tinuper, Paolo; Hirsch, Edouard; de Saint Martin, Anne; Chelly, Jamel; Rudolf, Gabrielle; Chipaux, Mathilde; Ferrand-Sorbets, Sarah; Dorfmüller, Georg; Sisodiya, Sanjay; Balestrini, Simona; Schoeler, Natasha; Hernandez-Hernandez, Laura; Krithika, S.; Oegema, Renske; Hagebeuk, Eveline; Gunning, Boudewijn; Deckers, Charles; Berghuis, Bianca; Wegner, Ilse; Niks, Erik; Jansen, Floor E.; Braun, Kees; de Jong, Daniëlle; Rubboli, Guido; Talvik, Inga; Sander, Valentin; Uldall, Peter; Jacquemont, Marie Line; Nava, Caroline; Leguern, Eric; Julia, Sophie; Gambardella, Antonio; d’Orsi, Giuseppe; Crichiutti, Giovanni; Faivre, Laurence; Darmency, Veronique; Benova, Barbora; Krsek, Pavel; Biraben, Arnaud; Lebre, Anne Sophie; Jennesson, Mélanie; Sattar, Shifteh; Marchal, Cécile; Nordli, Douglas R.; Lindstrom, Kristin; Striano, Pasquale; Lomax, Lysa Boissé; Kiss, Courtney; Bartolomei, Fabrice; Lepine, Anne Fabienne; Schoonjans, An Sofie; Stouffs, Katrien; Jansen, Anna; Panagiotakaki, Eleni; Ricard-Mousnier, Brigitte; Thevenon, Julien; de Bellescize, Julitta; Catenoix, Hélène; Dorn, Thomas; Zenker, Martin; Müller-Schlüter, Karen; Brandt, Christian; Krey, Ilona; Polster, Tilman; Wolff, Markus; Balci, Meral; Rostasy, Kevin; Achaz, Guillaume; Zacher, Pia; Becher, Thomas; Cloppenborg, Thomas; Yuskaitis, Christopher J.; Weckhuysen, Sarah; Poduri, Annapurna; Lemke, Johannes R.; Møller, Rikke S.; Baulac, Stéphanie; Baulac, Stéphanie (Lippincott Williams & Wilkins, 2019-02-01)
    Purpose: To define the phenotypic and mutational spectrum of epilepsies related to DEPDC5, NPRL2 and NPRL3 genes encoding the GATOR1 complex, a negative regulator of the mTORC1 pathway Methods: We analyzed clinical and ...
  • Cognitive and behavioural changes in PLS and PMA:challenging the concept of restricted phenotypes 
    de Vries, Bálint S; Rustemeijer, Laura M M; Bakker, Leonhard A; Schröder, Carin D; Veldink, Jan H; van den Berg, Leonard H; Nijboer, Tanja C W; van Es, Michael A (BMJ Publishing Group, 2019-02)
    OBJECTIVES: Cognitive and behavioural changes within the spectrum of frontotemporal dementia (FTD) are observed frequently in patients with amyotrophic lateral sclerosis (ALS). Whether these changes also occur in other ...
  • Association between alcohol exposure and the risk of amyotrophic lateral sclerosis in the Euro-MOTOR study 
    D'Ovidio, Fabrizio; Rooney, James P K; Visser, Anne E; Manera, Umberto; Beghi, Ettore; Logroscino, Giancarlo; Vermeulen, Roel C H; Veldink, Jan Herman; van den Berg, Leonard H; Hardiman, Orla; Chiò, Adriano; Euro-MOTOR Consortium (BMJ Publishing Group, 2019-01)
    OBJECTIVES: Several studies focused on the association between alcohol consumption and amyotrophic lateral sclerosis (ALS), although with inconsistent findings. Antioxidants may play a role since lyophilised red wine was ...
  • Polymerase Chain Reaction and Goldmann-Witmer Coefficient to Examine the Role of Epstein-Barr Virus in Uveitis 
    Smit, Derrick; Meyer, David; Maritz, Jean; de Groot-Mijnes, Jolanda D.F. (Informa Healthcare, 2019-01-02)
    Purpose: To use polymerase chain reaction (PCR) and Goldmann-Witmer Coefficient (GWC) calculation to search for evidence that Epstein-Barr virus (EBV) causes uveitis. Methods: A prospective cross-sectional study where ...
  • The development of an online decision aid to support persons having a genetic predisposition to cancer and their partners during reproductive decision-making: a usability and pilot study 
    Reumkens, Kelly; Tummers, Marly H.E.; Gietel-Habets, Joyce J.G.; van Kuijk, Sander M.J.; Aalfs, Cora M.; van Asperen, Christi J.; Ausems, Margreet G.E.M.; Collée, Margriet; Dommering, Charlotte J.; Kets, C. Marleen; van der Kolk, Lizet E.; Oosterwijk, Jan C.; Tjan-Heijnen, Vivianne C.G.; van der Weijden, Trudy; de Die-Smulders, Christine E.M.; van Osch, Liesbeth A.D.M. (Springer Netherlands, 2019-01)
    An online decision aid to support persons having a genetic predisposition to cancer and their partners during reproductive decision-making was developed. A two-phase usability test was conducted among 12 couples (N = 22; ...
  • Association of Maternal Prepregnancy Body Mass Index With Placental Histopathological Characteristics in Uncomplicated Term Pregnancies 
    Brouwers, Laura; Franx, Arie; Vogelvang, Tatjana E; Houben, Michiel L; van Rijn, Bas B; Nikkels, Peter Gj (SAGE Publications Inc., 2019-01-01)
    Introduction Prepregnancy obesity is a growing global health problem and has several risks for mother and child. The aim of this study was to systematically examine the effect of increased maternal body mass index (BMI) ...
  • Validity of injury self-reports by novice runners: comparison with reports by sports medicine physicians 
    Smits, Dirk Wouter; Backx, Frank; Van Der Worp, Henk; Van Middelkoop, Marienke; Hartgens, Fred; Verhagen, Evert; Kluitenberg, Bas; Huisstede, Bionka (Taylor and Francis Ltd., 2019-01-02)
    This study examined the criterion validity of self-reported running-related injuries (RRI) by novice runners. Fifty-eight participants (41 females; age 46 ± 11 yrs) of the “Start-to-Run” program provided self-reports on ...
  • Reasons and predictors of discontinuation of running after a running program for novice runners 
    Fokkema, Tryntsje; Hartgens, Fred; Kluitenberg, Bas; Verhagen, Evert; Backx, Frank J.G.; van der Worp, Henk; Bierma-Zeinstra, Sita M.A.; Koes, Bart W.; van Middelkoop, Marienke (Elsevier, 2019-01)
    Objectives: To determine the proportion of participants of a running program for novice runners that discontinued running and investigate the main reasons to discontinue and characteristics associated with discontinuation. ...
  • Overview of the clinical implementation of a study exploring social withdrawal in patients with schizophrenia and Alzheimer's disease 
    Bilderbeck, Amy C; Penninx, Brenda W J H; Arango, Celso; van der Wee, Nic; Kahn, René; Winter-van Rossum, Inge; Hayen, Anja; Kas, Martien J; Post, Anke; Dawson, Gerard R (Elsevier Limited, 2019-02)
    Trans-diagnostic, domain- or symptom-focused approaches have been heralded as advancing psychiatric research, but relatively few clinical research programmes have been undertaken to leverage their potential. In this ...
  • The Amsterdam ReBus progressor cohort: Identification of 165 Barrett's surveillance patients who progressed to early neoplasia and 723 nonprogressor patients 
    Duits, L. C.; Klaver, E.; Bureo Gonzalez, A.; Boerwinkel, D. F.; Ten Kate, F. J.W.; Offerhaus, G. J.A.; Meijer, S. L.; Visser, M.; Seldenrijk, C. A.; Krishnadath, K. K.; Schoon, E. J.; Weusten, Bas L.A.M.; Mallant-Hent, Rosalie C.; Pouw, Roos E.; Bergman, Jacques J.G.H.M. (Wiley-Blackwell, 2019-09)
    Patient selection is suboptimal in most studies focused on identifying biological markers for neoplastic progression in Barrett's esophagus (BE). This study aims to describe a stringently selected community-based casecontrol ...
  • Therapeutic Drug Monitoring of Oral Anti-Hormonal Drugs in Oncology 
    Groenland, Stefanie L; van Nuland, Merel; Verheijen, Remy B; Schellens, Jan H M; Beijnen, Jos H; Huitema, Alwin D R; Steeghs, Neeltje (Adis, 2019-03)
    Oral anti-hormonal drugs are essential in the treatment of breast and prostate cancer. It is well known that the interpatient variability in pharmacokinetic exposure is high for these agents and exposure-response relationships ...
  • Reply 
    Opstelten, Jorrit L; Oldenburg, Bas (John Wiley & Sons Inc., 2019-02)
    refers to reply on: Prediagnostic Serum Vitamin D Levels and the Risk of Crohn’s Disease and Ulcerative Colitis in European Populations: A Nested Case-Control Study
  • Auditory hallucinations in adults with hearing impairment: a large prevalence study 
    Linszen, M. M.J.; van Zanten, G. A.; Teunisse, R. J.; Brouwer, R. M.; Scheltens, P.; Sommer, I. E. (Cambridge University Press, 2019-01)
    BACKGROUND: Similar to visual hallucinations in visually impaired patients, auditory hallucinations are often suggested to occur in adults with hearing impairment. However, research on this association is limited. This ...
  • Support needs of caregivers of patients with amyotrophic lateral sclerosis: A qualitative study 
    de Wit, Jessica; Schröder, Carin D; El Mecky, Julia; Beelen, Anita; van den Berg, Leonard H; Visser-Meily, Johanna M A (Cambridge University Press, 2019-04)
    OBJECTIVE: The aim of this study was to explore the support needs of Dutch informal caregivers of patients with amyotrophic lateral sclerosis (ALS). METHOD: Individual semi-structured interviews were conducted with 21 ...
  • Actual versus recommended storage temperatures of oral anticancer medicines at patients' homes 
    Vlieland, N D; van den Bemt, Bjf; van Riet-Nales, Diana A.; Bouvy, Marcel L; Egberts, ACG; Gardarsdottir, H (SAGE Publications Ltd, 2019-03-01)
    Background Substantial quantities of unused medicines are returned by patients to the pharmacy each year. Redispensing these medicines would reduce medicinal waste and health care costs. However, it is not known if medicines ...
  • Improving individual predictions: Machine learning approaches for detecting and attacking heterogeneity in schizophrenia (and other psychiatric diseases) 
    Schnack, Hugo G. (Elsevier, 2019-12)
    Psychiatric diseases are very heterogeneous both in clinical manifestation and etiology. With the recent rise of using machine learning techniques to attempt to diagnose and prognose these disorders, the issue of heterogeneity ...
  • Operative Treatment of Pediatric Pelvic and Acetabulum Fractures 
    de Ridder, Victor A.; Olson, Steven A. (Lippincott Williams & Wilkins, 2019-12-01)
    Pediatric pelvic fractures are rare and differ from adults in etiology, fracture type, and associated injuries. They are observed in multitrauma patients, with severe associated injuries. Treatment of these children in ...