Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

Now showing items 21981-22000 of 40729

Potential of mesenchymal- and cardiac progenitor cells for therapeutic targeting of B-cells and antibody responses in end-stage heart failure

van den Hoogen, Patricia; de Jager, Saskia C A; Mol, Emma A; Schoneveld, Arjan S; Huibers, Manon M H; Vink, Aryan; Doevendans, Pieter A; Laman, Jon D; Sluijter, Joost P G (Public Library of Science, 2019-01-01)

Upon myocardial damage, the release of cardiac proteins induces a strong antibody-mediated immune response, which can lead to adverse cardiac remodeling and eventually heart failure (HF). Stem cell therapy using mesenchymal ...
Circulating Serum MicroRNAs as Potential Diagnostic Biomarkers of Posttraumatic Stress Disorder: A Pilot Study

Snijders, Clara; Krauskopf, Julian; Pishva, Ehsan; Eijssen, Lars; Machiels, Barbie; Kleinjans, Jos; Kenis, Gunter; van den Hove, Daniel; Kim, Myeong Ok; Boks, Marco P.M.; Vinkers, Christiaan H.; Vermetten, Eric; Geuze, Elbert; Rutten, Bart P.F.; de Nijs, Laurence (Frontiers Media S. A., 2019-11-22)

Posttraumatic stress disorder (PTSD) is a psychiatric disorder that can develop upon exposure to a traumatic event. While most people are able to recover promptly, others are at increased risk of developing PTSD. However, ...
The Potential of Cannabidiol as a Treatment for Psychosis and Addiction: Who Benefits Most? A Systematic Review

Batalla, Albert; Janssen, Hella; Gangadin, Shiral S; Bossong, Matthijs G (Multidisciplinary Digital Publishing Institute (MDPI), 2019-07-19)

The endogenous cannabinoid (eCB) system plays an important role in the pathophysiology of both psychotic disorders and substance use disorders (SUDs). The non-psychoactive cannabinoid compound, cannabidiol (CBD) is a highly ...
The JCBFM Symposium at BRAIN 2019

Dijkhuizen, Rick M. (SAGE Publications Inc., 2020-01)

A symposium dedicated to the readership of the Journal of Cerebral Blood Flow and Metabolism was organized by the Journal’s editorial team at the BRAIN 2019 meeting in Yokohama, Japan. The JCBFM Symposium offered excellent ...
Erratum: Correction to: Validation of the Aldosteronoma Resolution Score Within Current Clinical Practice (World journal of surgery (2019) 43 10 (2459-2468))

International CONNsortium study group (Springer New York, 2020-01-01)

In the original article, two of the International CONNsortium Study Group collaborator’s names are spelled wrong: Anton F. Engelsman and Els J.M. Nieveen van Dijkum. The spellings are correct as reflected here.
Prediction of Severe Lymphopenia During Chemoradiation Therapy for Esophageal Cancer: Development and Validation of a Pretreatment Nomogram

van Rossum, Peter S N; Deng, Wei; Routman, David M; Liu, Amy Y; Xu, Cai; Shiraishi, Yutaka; Peters, Max; Merrell, Kenneth W; Hallemeier, Christopher L; Mohan, Radhe; Lin, Steven H (Elsevier, 2020-01-01)

Introduction: In patients with esophageal cancer, occurrence of severe radiation-induced lymphopenia during chemoradiation therapy has been associated with worse progression-free and overall survival. The aim of this study ...
Efficacy and safety of IVIG in CIDP: Combined data of the PRIMA and PATH studies

Merkies, Ingemar S J; van Schaik, Ivo N; Léger, Jean-Marc; Bril, Vera; van Geloven, Nan; Hartung, Hans-Peter; Lewis, Richard A; Sobue, Gen; Lawo, John-Philip; Durn, Billie L; Cornblath, David R; De Bleecker, Jan L; Sommer, Claudia; Robberecht, Wim; Saarela, Mika; Kamienowski, Jerzy; Stelmasiak, Zbigniew; Tackenberg, Björn; Mielke, Orell; PRIMA Trial Investigators and the PATH Study Group (Wiley-Blackwell, 2019-03)

Intravenous immunoglobulin (IVIG) is a potential therapy for chronic inflammatory demyelinating polyneuropathy (CIDP). To investigate the efficacy and safety of the IVIG IgPro10 (Privigen) for treatment of CIDP, results ...
Multivariate genome-wide analysis of stress-related quantitative phenotypes

Schijven, Dick; Geuze, Elbert; Vinkers, Christiaan H.; Pulit, Sara L.; Schür, Remmelt R.; Malgaz, Marie; Bekema, Erwin; Medic, Jelena; van der Kust, Kendrick E.; Veldink, Jan H.; Boks, Marco P.; Vermetten, Eric; Luykx, Jurjen J. (Elsevier, 2019-12)

Exposure to traumatic stress increases the odds of developing a broad range of psychiatric conditions. Genetic studies targeting multiple stress-related quantitative phenotypes may shed light on mechanisms underlying ...
Reward-Related Striatal Responses Following Stress in Healthy Individuals and Patients With Bipolar Disorder

van Leeuwen, Judith M C; Vink, Matthijs; Joëls, Marian; Kahn, René S; Hermans, Erno J; Vinkers, Christiaan H (Elsevier, 2019-11)

BACKGROUND: Stress has a major impact on the onset and recurrence of mood episodes in bipolar disorder (BD), but the underlying mechanisms remain unknown. Previous studies have shown distinct time-dependent effects of ...
Validated inference of smoking habits from blood with a finite DNA methylation marker set

BIOS Consortium (Springer Netherlands, 2019-11)

Inferring a person's smoking habit and history from blood is relevant for complementing or replacing self-reports in epidemiological and public health research, and for forensic applications. However, a finite DNA methylation ...
Hypothalamic-Pituitary Disorders in Childhood Cancer Survivors: Prevalence, Risk Factors and Long-Term Health Outcomes

van Iersel, Laura; Li, Zhenghong; Srivastava, Deo Kumar; Brinkman, Tara M.; Bjornard, Kari L.; Wilson, Carmen L.; Green, Daniel M.; Merchant, Thomas E.; Pui, Ching Hon; Howell, Rebecca M.; Smith, Susan A.; Armstrong, Gregory T.; Hudson, Melissa M.; Robison, Leslie L.; Ness, Kirsten K.; Gajjar, Amar; Krull, Kevin R.; Sklar, Charles A.; van Santen, Hanneke M.; Chemaitilly, Wassim (Endocrine Society, 2019-12-01)

CONTEXT: Data on hypothalamic-pituitary (HP) disorders in systematically evaluated childhood cancer survivors are limited. OBJECTIVE: To describe prevalence, risk factors, and associated adverse health outcomes of deficiencies ...
Human immune globulin 10% with recombinant human hyaluronidase in multifocal motor neuropathy

Herraets, Ingrid J T; Bakers, Jaap N E; van Eijk, Ruben P A; Goedee, H Stephan; van der Pol, W Ludo; van den Berg, Leonard H (Springer Science and Business Media Deutschland GmbH, 2019-11)

Objective: The primary aim was to determine the safety of treatment with human immune globulin 10% with recombinant human hyaluronidase (fSCIg) compared to intravenous immunoglobulin (IVIg) in a prospective open-label study ...
Trust and the city: Linking urban upbringing to neural mechanisms of trust in psychosis

Lemmers-Jansen, Imke Lj; Fett, Anne-Kathrin J; van Os, Jim; Veltman, Dick J; Krabbendam, Lydia (Informa Healthcare, 2019-08-14)

Objective: Elevated prevalence of non-affective psychotic disorders is often found in densely populated areas. This functional magnetic resonance imaging study investigates if reduced trust, a component of impaired social ...
Genetic and environmental influences on functional connectivity within and between canonical cortical resting-state networks throughout adolescent development in boys and girls

Teeuw, Jalmar; Brouwer, Rachel M; Guimarães, João P O F T; Brandner, Philip; Koenis, Marinka M G; Swagerman, Suzanne C; Verwoert, Maxime; Boomsma, Dorret I; Hulshoff Pol, Hilleke E (Academic Press Inc., 2019-11-15)

The human brain is active during rest and hierarchically organized into intrinsic functional networks. These functional networks are largely established early in development, with reports of a shift from a local to more ...
Remote sensing and signaling in kidney proximal tubules stimulates gut microbiome-derived organic anion secretion

Jansen, Jitske; Jansen, Katja; Neven, Ellen; Poesen, Ruben; Othman, Amr; van Mil, Alain; Sluijter, Joost; Torano, Javier Sastre; Zaal, Esther A.; Berkers, Celia R.; Esser, Diederik; Wichers, Harry J.; van Ede, Karin; van Duursen, Majorie; Burtey, Stéphane; Verhaar, Marianne C.; Meijers, Björn; Masereeuw, Rosalinde (National Academy of Sciences, 2019-08-06)

Membrane transporters and receptors are responsible for balancing nutrient and metabolite levels to aid body homeostasis. Here, we report that proximal tubule cells in kidneys sense elevated endogenous, gut microbiome-derived, ...
Utrecht Pediatric Wheelchair Mobility Skills Test: Reliability, Validity, and Responsiveness in Youths Using a Manual Wheelchair

Sol, Marleen E; de Groot, Janke F; Zwinkels, Maremka; Visser-Meily, J M Anne; Kruitwagen, Cas L J J; Verschuren, Olaf (Oxford University Press, 2019-08)

BACKGROUND: The assessment of wheelchair mobility skills (WMS) in youths using a manual wheelchair is important. More information is needed regarding the psychometric properties of the newly developed Utrecht Pediatric ...
Loss of appetite is associated with a loss of weight and fat mass in patients with amyotrophic lateral sclerosis

Ngo, Shyuan T; van Eijk, Ruben P A; Chachay, V; van den Berg, Leonard H; McCombe, Pamela A; Henderson, Robert D; Steyn, Frederik J (Informa Healthcare, 2019-11)

Objective: Weight loss in amyotrophic lateral sclerosis (ALS) is associated with faster disease progression and shorter survival. It has different possible causes, including loss of appetite. Our objective is to determine ...
Two heads are better than one: benefits of joint models for ALS trials

van Eijk, Ruben P A; Rooney, James; Hardiman, Orla; van den Berg, Leonard H (BMJ Publishing Group, 2019-09)
Participation and mental well-being of mothers of home-living patients with spinal muscular atrophy

Cremers, C H; Fischer, M J; Kruitwagen-van Reenen, E T; Wadman, R I; Vervoordeldonk, J J; Verhoef, M; Visser-Meily, J M; van der Pol, W L; Schröder, C D (Elsevier Limited, 2019-04)

Proximal spinal muscular atrophy (SMA) causes severe physical limitations but also has a major impact on the lives of parents. The aim of this study was to investigate participation and mental well-being (burden, emotional ...
Occupation and motor neuron disease: a New Zealand case-control study

Chen, Grace Xia; 't Mannetje, Andrea Martine; Douwes, Jeroen; van den Berg, Leonard; Pearce, Neil; Kromhout, Hans; D'Souza, Wendyl; McConnell, Melanie; Glass, Bill; Brewer, Naomi; McLean, David J (BMJ Publishing Group, 2019-05)

OBJECTIVES: To assess associations between occupation and motor neuron disease (MND). METHODS: We conducted a population-based case-control study with cases (n=321) recruited through the New Zealand Motor Neurone Disease ...

Now showing items 21981-22000 of 40729