Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

Now showing items 21921-21940 of 40729

Deep learning-based MR-to-CT synthesis: The influence of varying gradient echo-based MR images as input channels

Florkow, Mateusz C; Zijlstra, Frank; Willemsen, Koen; Maspero, Matteo; van den Berg, Cornelis A T; Kerkmeijer, Linda G W; Castelein, René M; Weinans, Harrie; Viergever, Max A; van Stralen, Marijn; Seevinck, Peter R (John Wiley & Sons Inc., 2020-04)

PURPOSE: To study the influence of gradient echo-based contrasts as input channels to a 3D patch-based neural network trained for synthetic CT (sCT) generation in canine and human populations. METHODS: Magnetic resonance ...
Gastric cancer during pregnancy: a report on 13 cases and review of the literature with focus on chemotherapy during pregnancy

International Network on Cancer, Infertility, Pregnancy (INCIP) (Wiley-Blackwell, 2020-01-01)

Introduction: Gastric cancer during pregnancy is extremely rare and data on optimal treatment and possible chemotherapeutic regimens are scarce. The aim of this study is to describe the obstetric and maternal outcome of ...
Homozygous damaging SOD2 variant causes lethal neonatal dilated cardiomyopathy

Almomani, Rowida; Herkert, Johanna C.; Posafalvi, Anna; Post, Jan G.; Boven, Ludolf G.; Van Der Zwaag, Paul A.; Willems, Peter H.G.M.; Van Veen-Hof, Ingrid H.; Verhagen, Judith M.A.; Wessels, Marja W.; Nikkels, Peter G.J.; Wintjes, Liesbeth T.; Van Den Berg, Maarten P.; Sinke, Richard J.; Rodenburg, Richard J.; Niezen-Koning, Klary E.; Van Tintelen, J. Peter; Jongbloed, Jan D.H. (BMJ Publishing Group, 2020-01-01)

Background: Idiopathic dilated cardiomyopathy (DCM) is recognised to be a heritable disorder, yet clinical genetic testing does not produce a diagnosis in >50% of paediatric patients. Identifying a genetic cause is crucial ...
Formal assessment of the learning curve for minimally invasive methods is vital in retrospective cohort studies

Van Boxel, Gijs I; Feike Kingma, B; Ruurda, Jelle P (Mosby Inc., 2020-01)
Comment on Transient Tachypnea of the Newborn Is Associated With an Increased Risk of Hospitalization Due to Respiratory Syncytial Virus Bronchiolitis

van de Kam, Lieke W.P.C.G.; Korsten, Koos; Wildenbeest, Joanne G.; Bont, Louis J. (Lippincott Williams & Wilkins, 2019-09-01)
LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation

Profumo, Valentina; Forte, Barbara; Percio, Stefano; Rotundo, Federica; Doldi, Valentina; Ferrari, Elena; Fenderico, Nicola; Dugo, Matteo; Romagnoli, Dario; Benelli, Matteo; Valdagni, Riccardo; Dolfini, Diletta; Zaffaroni, Nadia; Gandellini, Paolo (Nature Publishing Group, 2019-12-01)

Though miR-205 function has been largely characterized, the nature of its host gene, MIR205HG, is still completely unknown. Here, we show that only lowly expressed alternatively spliced MIR205HG transcripts act as de facto ...
The reduction of astrocytes and brain volume loss in anorexia nervosa—the impact of starvation and refeeding in a rodent model

Frintrop, Linda; Trinh, Stefanie; Liesbrock, Johanna; Leunissen, Christina; Kempermann, Julia; Etdöger, Serhat; Kas, Martien J.; Tolba, René; Heussen, Nicole; Neulen, Joseph; Konrad, Kerstin; Päfgen, Vera; Kiessling, Fabian; Herpertz-Dahlmann, Beate; Beyer, Cordian; Seitz, Jochen (Nature Publishing Group, 2019-12-01)

Anorexia nervosa (AN) is an often chronic, difficult to treat illness that leads to brain volume reductions in gray and white matter. The underlying pathophysiology is poorly understood, despite its potential importance ...
Publisher Correction: Complement-dependent outer membrane perturbation sensitizes Gram-negative bacteria to Gram-positive specific antibiotics (Scientific Reports, (2018), 8, 1, (15409), 10.1038/s41598-018-33850-9)

Heesterbeek, D. A.C.; Martin, N. I.; Velthuizen, A.; Duijst, M.; Ruyken, M.; Wubbolts, R.; Rooijakkers, S. H.M.; Bardoel, B. W. (Nature Publishing Group, 2019-12-01)

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Complement-dependent outer membrane perturbation sensitizes Gram-negative bacteria to Gram-positive specific antibiotics

Heesterbeek, D. A.C.; Martin, N. I.; Velthuizen, A.; Duijst, M.; Ruyken, M.; Wubbolts, R.; Rooijakkers, S. H.M.; Bardoel, B. W. (Nature Publishing Group, 2019-12-01)

Gram-negative bacteria are refractory to the action of many antibiotics due to their impermeable outer membrane. An important player of the immune system is the complement system, a protein network in serum that directly ...
Fibroblast growth factor receptor signaling in pediatric B-cell precursor acute lymphoblastic leukemia

Jerchel, Isabel S.; Hoogkamer, Alex Q.; Ariës, Ingrid M.; Boer, Judith M.; Besselink, Nicolle J.M.; Koudijs, Marco J.; Pieters, Rob; den Boer, Monique L. (Nature Publishing Group, 2019-12-01)

The FGF receptor signaling pathway is recurrently involved in the leukemogenic processes. Oncogenic fusions of FGFR1 with various fusion partners were described in myeloid proliferative neoplasms, and overexpression and ...
Outcomes of Retreatment for Intracranial Aneurysms-A Meta-Analysis

Muskens, Ivo S.; Hertgers, Omar; Lycklama À Nijeholt, Geert J.; Broekman, Marike L.D.; Moojen, Wouter A. (Lippincott Williams & Wilkins, 2019-12-01)

BACKGROUND: Long-term results from the International Subarachnoid Hemorrhage Trial (ISAT) and Barrow Ruptured Aneurysm Trial (BRAT) indicate considerably higher retreatment rates for aneurysms treated with coiling compared ...
Farnesoid X receptor and bile acids regulate vitamin A storage

Saeed, Ali; Yang, Jing; Heegsma, Janette; Groen, Albert K.; van Mil, Saskia W.C.; Paulusma, Coen C.; Zhou, Lu; Wang, Bangmao; Faber, Klaas Nico (Nature Publishing Group, 2019-12-01)

The nuclear receptor Farnesoid X Receptor (FXR) is activated by bile acids and controls multiple metabolic processes, including bile acid, lipid, carbohydrate, amino acid and energy metabolism. Vitamin A is needed for ...
De FUTURE trial; een multicenter RCT naar MRI-geleide prostaatbiopten: Vergelijking van drie technieken van target biopten en vergelijking met systematische biopten

Wegelin, O.; Exterkate, L.; Barentsz, J. O.; van der Leest, M. G.; Kelder, J. C.; Kummer, J. A.; Vreuls, W.; de Bruin, P. C.; de Vocht, T. F.; Nuininga, J. E.; Bosch, J. L.H.R.; Somford, D. M.; van Melick, H. H.E. (Springer Science + Business Media, 2019-12-01)

The FUTURE trial is a multicenter RCT on 3 MRI-based target biopsy (TB) techniques among patients with negative systematic biopsies (SBs) and persisting suspicion of prostate cancer. Between 2014 and 2017 665 patients ...
Balance, risk of falls, risk factors and fall-related costs in individuals with diabetes

Rinkel, Willem D.; van Nieuwkasteele, Shelly; Castro Cabezas, Manuel; van Neck, Johan W.; Birnie, Erwin; Coert, J. Henk (Elsevier Ireland Ltd, 2019-12-01)

Aims: Sensory loss and impaired balance are considered risk factors of incident falls. The aim of this study was to assess the relationship between degree of foot sensation and balance, risk of falls, incidence of fall-related ...
How scientists and physicians use Twitter during a medical congress

Cevik, M.; Ong, D. S.Y.; Mackenzie, G. (Elsevier, 2019-12-01)

OBJECTIVES: During medical congresses Twitter allows discussions to disseminate beyond the congress hall and reach a wider audience. Insights into the dynamics of social media interactions during congresses, dissemination ...
Trial-based cost-effectiveness analysis of ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) versus DSAEK

Simons, Rob W.P.; Dickman, Mor M.; van den Biggelaar, Frank J.H.M.; Dirksen, Carmen D.; Van Rooij, Jeroen; Remeijer, Lies; Van der Lelij, Allegonda; Wijdh, Robert H.J.; Kruit, Pieter J.; Nuijts, Rudy M.M.A. (Wiley-Blackwell, 2019-12-01)

Purpose: To evaluate the cost-effectiveness of ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) versus standard DSAEK. Methods: A cost-effectiveness analysis using data from a multicentre randomized ...
Generation of Fibrodysplasia ossificans progressiva and control integration free iPSC lines from periodontal ligament fibroblasts

Sanchez-Duffhues, G.; Mikkers, H.; de Jong, D.; Szuhai, K.; de Vries, T. J.; Freund, C.; Bravenboer, N.; van Es, R. J.J.; Netelenbos, J. C.; Goumans, M. J.; Eekhoff, E. M.W.; ten Dijke, P. (Elsevier, 2019-12-01)

Fibrodysplasia ossificans progressiva (FOP) is a very rare devastating heterotopic ossification disorder, classically caused by a heterozygous single point mutation (c.617G>A) in the ACVR1gene, encoding the Bone morphogenetic ...
Development and proof of concept of a blended physiotherapeutic intervention for patients with non-specific low back pain

Kloek, C. J.J.; van Tilburg, M. L.; Staal, J. B.; Veenhof, C.; Bossen, D. (Elsevier, 2019-12-01)

Objective: To develop a blended physiotherapeutic intervention for patients with non-specific low back pain (e-Exercise LBP) and evaluate its proof of concept. Design: Focus groups with patients, physiotherapists, and ...
Air pollution during New Year’s fireworks and daily mortality in the Netherlands

Greven, Frans E.; Vonk, Judith M.; Fischer, Paul; Duijm, Frans; Vink, Nienke M.; Brunekreef, Bert (Nature Publishing Group, 2019-12-01)

Short-term exposure to air pollution has been associated with cardiovascular and respiratory mortality and morbidity. Little is known about associations between air pollution caused by firework events and daily mortality. ...
Bladder-bowel interactions: Do we understand pelvic organ cross-sensitization? International Consultation on Incontinence Research Society (ICI-RS) 2018

Panicker, Jalesh N.; Marcelissen, Tom; von Gontard, Alexander; Vrijens, Desiree; Abrams, Paul; Wyndaele, Michel (John Wiley & Sons Inc., 2019-12-01)

Aims: Mounting evidence from experimental animal and human studies suggests that cross-sensitization exists between different organs. Lower urinary tract (LUT) and bowel dysfunction commonly overlap, and the role of ...

Now showing items 21921-21940 of 40729