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UMC Repository: Recent submissions

  • Lactobacilli-containing vaginal probiotics to cure or prevent bacterial or fungal vaginal dysbiosis: a systematic review and recommendations for future trial designs 
    van de Wijgert, Jhhm; Verwijs, M C (Wiley-Blackwell, 2020-01-01)
    BACKGROUND: Vaginal probiotics claiming to cure and/or prevent bacterial and/or fungal vaginal dysbiosis are available on the market but, until recently, did not have to be approved as drugs for human use. OBJECTIVES: We ...
  • Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial 
    Butler, Christopher C; van der Velden, Alike W; Bongard, Emily; Saville, Benjamin R; Holmes, Jane; Coenen, Samuel; Cook, Johanna; Francis, Nick A; Lewis, Roger J; Godycki-Cwirko, Maciek; Llor, Carl; Chlabicz, Sławomir; Lionis, Christos; Seifert, Bohumil; Sundvall, Pär-Daniel; Colliers, Annelies; Aabenhus, Rune; Bjerrum, Lars; Jonassen Harbin, Nicolay; Lindbæk, Morten; Glinz, Dominik; Bucher, Heiner C; Kovács, Bernadett; Radzeviciene Jurgute, Ruta; Touboul Lundgren, Pia; Little, Paul; Murphy, Andrew W; De Sutter, An; Openshaw, Peter; de Jong, Menno D; Connor, Jason T; Matheeussen, Veerle; Ieven, Margareta; Goossens, Herman; Verheij, Theo J (Elsevier, 2020-01-04)
    BACKGROUND: Antivirals are infrequently prescribed in European primary care for influenza-like illness, mostly because of perceived ineffectiveness in real world primary care and because individuals who will especially ...
  • Role of eHealth application Oncokompas in supporting self-management of symptoms and health-related quality of life in cancer survivors: a randomised, controlled trial 
    van der Hout, Anja; van Uden-Kraan, Cornelia F; Holtmaat, Karen; Jansen, Femke; Lissenberg-Witte, Birgit I; Nieuwenhuijzen, Grard A P; Hardillo, José A; Baatenburg de Jong, Robert J; Tiren-Verbeet, Nicolette L; Sommeijer, Dirkje W; de Heer, Koen; Schaar, Cees G; Sedee, Robert-Jan E; Bosscha, Koop; van den Brekel, Michiel W M; Petersen, Japke F; Westerman, Matthijs; Honings, Jimmie; Takes, Robert P; Houtenbos, Ilse; van den Broek, Wim T; de Bree, Remco; Jansen, Patricia; Eerenstein, Simone E J; Leemans, C René; Zijlstra, Josée M; Cuijpers, Pim; van de Poll-Franse, Lonneke V; Verdonck-de Leeuw, Irma M (Elsevier Limited, 2020-01)
    BACKGROUND: Knowledge about the efficacy of behavioural intervention technologies that can be used by cancer survivors independently from a health-care provider is scarce. We aimed to assess the efficacy, reach, and usage ...
  • Exposure and response analysis of aleglitazar on cardiovascular risk markers and safety outcomes: An analysis of the AleCardio trial 
    Koomen, Jeroen V; Heerspink, Hiddo J L; Schrieks, Ilse C; Schwartz, Gregory G; Lincoff, A Michael; Nicholls, Stephen J; Svensson, Anders; Wedel, Hans; Weichert, Arlette; Grobbee, Diederick E; Stevens, Jasper (Wiley-Blackwell, 2020-01)
    Aims: The AleCardio trial aimed to characterize the efficacy and safety of peroxisome proliferator-activated receptor-αγ agonist aleglitazar in patients with type 2 diabetes mellitus and acute coronary syndrome. The trial ...
  • The cardiovascular risk profile of middle-aged women with polycystic ovary syndrome 
    Meun, Cindy; Gunning, Marlise N.; Louwers, Yvonne, V; Peters, Henrike; Roos-Hesselink, Jolien; van Lennep, Jeanine Roeters; Rueda Ochoa, Oscar-Leonel; Appelman, Yolande; Lambalk, Nils; Boersma, Eric; Kavousi, Maryam; Fauser, Bart C. J. M.; Laven, Joop S. E.; Baart, Sara; Benschop, Laura; Brouwers, Laura; Budde, Ricardo; Cannegieter, Suzanne; Dam, Veerle; Eijkemans, Rene; Fauser, Bart C. J. M.; Ferrari, Michel; Franx, Arie; de Groot, Christianne; Gunning, Marlise N.; Hoek, Annemieke; Koffijberg, Erik; Koster, Wendy; Kruit, Mark; Lagerweij, Giske; Laven, Joop; Linstra, Katie; van der Lugt, Aad; Maas, Angela; van den Brink, Antoinette Maassen; Middeldorp, Saskia; Moons, Karel G. M.; van Rijn, Bas; Scheres, Luuk; van der Schouw, Yvonne T.; Steegers, Eric; Steegers, Regine; Terwindt, Gisela; Velthuis, Birgitta; Wermer, Marieke; Zick, Bart; Zoet, Gerbrand (Wiley-Blackwell, 2020-02-01)
    OBJECTIVES: Contradictory results have been reported regarding the association between polycystic ovary syndrome (PCOS) and cardiovascular disease (CVD). We assessed the cardiometabolic phenotype and prevalence of CVD in ...
  • Genetic Obesity and Bariatric Surgery Outcome in 1014 Patients with Morbid Obesity 
    Cooiman, M. I.; Kleinendorst, L.; Aarts, E. O.; Janssen, I. M.C.; van Amstel, H. K.Ploos; Blakemore, A. I.; Hazebroek, E. J.; Meijers-Heijboer, H. J.; van der Zwaag, B.; Berends, F. J.; van Haelst, M. M. (Springer New York, 2020-02)
    BACKGROUND: Mutations in the leptin-melanocortin pathway genes are known to cause monogenic obesity. The prevalence of these gene mutations and their effect on weight loss response after bariatric surgery are still largely ...
  • Accounting for time-dependent treatment use when developing a prognostic model from observational data: A review of methods 
    Pajouheshnia, Romin; Schuster, Noah A.; Groenwold, Rolf H.H.; Rutten, Frans H.; Moons, Karel G.M.; Peelen, Linda M. (Wiley-Blackwell, 2020-02-01)
    Failure to account for time-dependent treatment use when developing a prognostic model can result in biased future predictions. We reviewed currently available methods to account for treatment use when developing a prognostic ...
  • Treatment of hypercholesterolaemia in older adults calls for a patient-centred approach 
    Kleipool, Emma E.F.; Dorresteijn, Johannes A.N.; Smulders, Yvo M.; Visseren, Frank L.J.; Peters, Mike J.L.; Muller, Majon (BMJ Publishing Group, 2020-02)
    Due to an increasing number of older adults with (risk factors for) cardiovascular disease (CVD), the sum of older adults eligible for lipid-lowering drugs will increase. This has risen questions about benefits and harms ...
  • Age at menarche and heart failure risk: The EPIC-NL study 
    Plompen, Mitchell V L; van der Schouw, Yvonne T; Rutten, Frans H; Verschuren, W M Monique; Boer, Jolanda M A; Asselbergs, Folkert W; Onland-Moret, N Charlotte (Elsevier Ireland Ltd, 2020-01)
    AIMS: Early age at menarche has been reported to be associated with increased risks of developing type 2 diabetes (T2D) and coronary heart disease (CHD) in adulthood, but a late menarche has also been found to be associated ...
  • Platinum exposure and cause-specific mortality among patients with testicular cancer 
    Groot, Harmke J.; van Leeuwen, Flora E.; Lubberts, Sjoukje; Horenblas, Simon; de Wit, Ronald; Witjes, J. Alfred; Groenewegen, Gerard; Poortmans, Philip M.; Hulshof, Maarten C. C. M.; Meijer, Otto W. M.; de Jong, Igle J.; van den Berg, Hetty A.; Smilde, Tineke J.; Vanneste, Ben G. L.; Aarts, Maureen J. B.; Jozwiak, Katarzyna; van den Belt-Dusebout, Alexandra W.; Gietema, Jourik A.; Schaapveld, Michael (John Wiley & Sons Inc., 2020-02-01)
    Background: Although testicular cancer (TC) treatment has been associated with severe late morbidities, including second malignant neoplasms (SMNs) and ischemic heart disease (IHD), cause-specific excess mortality has been ...
  • One piece of the puzzle: Population pharmacokinetics of FVIII during perioperative Haemate P (R)/Humate P (R) treatment in von Willebrand disease patients: Population pharmacokinetics of FVIII during perioperative Haemate P®/Humate P® treatment in von Willebrand disease patients 
    for the OPTI-CLOT group (Wiley-Blackwell, 2020-02-01)
    Introduction: Many patients with von Willebrand disease (VWD) are treated on demand with von Willebrand factor and factor VIII (FVIII) containing concentrates present with VWF and/or FVIII plasma levels outside set target ...
  • The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study 
    VIP2 study group (Springer-Verlag, 2020-01)
    Purpose: Premorbid conditions affect prognosis of acutely-ill aged patients. Several lines of evidence suggest geriatric syndromes need to be assessed but little is known on their relative effect on the 30-day survival ...
  • EAU-ESMO Consensus Statements on the Management of Advanced and Variant Bladder Cancer—An International Collaborative Multistakeholder Effort †[Formula presented]: Under the Auspices of the EAU-ESMO Guidelines Committees 
    Witjes, J Alfred; Babjuk, Marek; Bellmunt, Joaquim; Bruins, H Maxim; De Reijke, Theo M; De Santis, Maria; Gillessen, Silke; James, Nicholas; Maclennan, Steven; Palou, Juan; Powles, Tom; Ribal, Maria J; Shariat, Shahrokh F; Der Kwast, Theo Van; Xylinas, Evanguelos; Agarwal, Neeraj; Arends, Tom; Bamias, Aristotle; Birtle, Alison; Black, Peter C; Bochner, Bernard H; Bolla, Michel; Boormans, Joost L; Bossi, Alberto; Briganti, Alberto; Brummelhuis, Iris; Burger, Max; Castellano, Daniel; Cathomas, Richard; Chiti, Arturo; Choudhury, Ananya; Compérat, Eva; Crabb, Simon; Culine, Stephane; De Bari, Berardino; De Blok, Willem; J L De Visschere, Pieter; Decaestecker, Karel; Dimitropoulos, Konstantinos; Dominguez-Escrig, Jose L; Fanti, Stefano; Fonteyne, Valerie; Frydenberg, Mark; Futterer, Jurgen J; Gakis, Georgios; Geavlete, Bogdan; Gontero, Paolo; Grubmüller, Bernhard; Hafeez, Shaista; Hansel, Donna E; Hartmann, Arndt; Hayne, Dickon; Henry, Ann M; Hernandez, Virginia; Herr, Harry; Herrmann, Ken; Hoskin, Peter; Huguet, Jorge; Jereczek-Fossa, Barbara A; Jones, Rob; Kamat, Ashish M; Khoo, Vincent; Kiltie, Anne E; Krege, Susanne; Ladoire, Sylvain; Lara, Pedro C; Leliveld, Annemarie; Linares-Espinós, Estefania; Løgager, Vibeke; Lorch, Anja; Loriot, Yohann; Meijer, Richard; Mir, M Carmen; Moschini, Marco; Mostafid, Hugh; Müller, Arndt-Christian; Müller, Christoph R; N'Dow, James; Necchi, Andrea; Neuzillet, Yann; Oddens, Jorg R; Oldenburg, Jan; Osanto, Susanne; J G Oyen, Wim; Pacheco-Figueiredo, Luís; Pappot, Helle; Patel, Manish I; Pieters, Bradley R; Plass, Karin; Remzi, Mesut; Retz, Margitta; Richenberg, Jonathan; Rink, Michael; Roghmann, Florian; Rosenberg, Jonathan E; Rouprêt, Morgan; Rouvière, Olivier; Salembier, Carl; Salminen, Antti; Sargos, Paul; Sengupta, Shomik; Sherif, Amir; Smeenk, Robert J; Smits, Anita; Stenzl, Arnulf; Thalmann, George N; Tombal, Bertrand; Turkbey, Baris; Lauridsen, Susanne Vahr; Valdagni, Riccardo; Der Heijden, Antoine G Van; Van Poppel, Hein; Vartolomei, Mihai D; Veskimäe, Erik; Vilaseca, Antoni; Rivera, Franklin A Vives; Wiegel, Thomas; Wiklund, Peter; Williams, Andrew; Zigeuner, Richard; Horwich, Alan (Elsevier, 2020-02-01)
    BACKGROUND: Although guidelines exist for advanced and variant bladder cancer management, evidence is limited/conflicting in some areas and the optimal approach remains controversial. OBJECTIVE: To bring together a large ...
  • High Variability of Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation 
    Sikma, Maaike A; Hunault, Claudine C; Van Maarseveen, Erik M; Huitema, Alwin D R; Van de Graaf, Ed A; Kirkels, Johannes H; Verhaar, Marianne C; Grutters, Jan C; Kesecioglu, Jozef; De Lange, Dylan W (Adis, 2020-02)
    BACKGROUND AND OBJECTIVE: Oral tacrolimus is initiated perioperatively in heart and lung transplantation patients. There have been few studies on oral tacrolimus pharmacokinetics early post-transplantation, even though ...
  • Postdoctoral nursing researcher career: A scoping review of required competences 
    Nurse Lead Consortium (Wiley-Blackwell Publishing Ltd, 2020-01)
    Aim: The aim of this review was to identify and summarize the required competences of nursing PhD students and postdoctoral researchers to pursue a successful researcher career and to compare these competences with the ...
  • The association between chronic kidney disease, falls, and fractures: a systematic review and meta-analysis 
    Goto, N A; Weststrate, A C G; Oosterlaan, F M; Verhaar, M C; Willems, H C; Emmelot-Vonk, M H; Hamaker, M E (Springer Science and Business Media Deutschland GmbH, 2020-01)
    Patients with chronic kidney disease (CKD) are more likely to experience falls and fractures due to renal osteodystrophy and the high prevalence of risk factors for falls. However, it is not well established how great the ...
  • Methodological aspects of the oxygenscan in sickle cell disease: A need for standardization 
    Rab, MAE; Kanne, Celeste K.; Bos, Jennifer; Boisson, Camille; van Oirschot, Brigitte A.; Nader, Elie; Renoux, Céline; Joly, Philippe; Fort, Romain; van Beers, Eduard J.; Sheehan, Vivien A.; van Wijk, Richard; Connes, Philippe (John Wiley & Sons Inc., 2020-01)
  • An automated workflow based on hip shape improves personalized risk prediction for hip osteoarthritis in the CHECK study 
    Gielis, W P; Weinans, H; Welsing, P M J; van Spil, W E; Agricola, R; Cootes, T F; de Jong, P A; Lindner, C (W.B. Saunders Ltd, 2020-01)
    OBJECTIVE: To design an automated workflow for hip radiographs focused on joint shape and tests its prognostic value for future hip osteoarthritis. DESIGN: We used baseline and 8-year follow-up data from 1,002 participants ...
  • Surgical Management of Enneking Stage 3 Aggressive Vertebral Hemangiomas with Neurological Deficit by One Stage Posterior Total en Bloc Spondylectomy: A Review of 23 Cases 
    Ji, Xinran; Wang, Song; Oner, F. Cumhur; Bird, Justin E.; Lu, Ning (Lippincott Williams & Wilkins, 2020-01-15)
    Study Design. Clinical case series.Objective.The aim of this study was to describe the treatment of aggressive vertebral hemangiomas (VHs) with neurological deficit treated with total en bloc spondylectomy (TES) in a single ...
  • Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database 
    Lefeber, Geert J.; Koek, Huiberdina L.; Souverein, Patrick C.; Bouvy, Marcel L.; de Boer, Anthonius; Knol, Wilma (Wiley-Blackwell, 2020-02-01)
    OBJECTIVE: To explore the effect of initiating statins for secondary prevention after a first myocardial infarction (MI) in patients aged 80 years and older. DESIGN: Retrospective cohort study. SETTING: Clinical Practice ...