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UMC Repository: Recent submissions

  • Association Between Soft Drink Consumption and Mortality in 10 European Countries 
    EPIC (American Medical Association, 2019-11)
    Importance: Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date. Objective: To examine the association ...
  • Attitude and behaviour of Dutch Otorhinolaryngologists to Evidence Based Medicine 
    Rademaker, Maaike M.; Smit, Adriana L.; Kortekaas, Marlous F.; Van Benthem, Peter Paul G.; Stegeman, Inge (Public Library of Science, 2019-01-01)
    Objective The objective of this study was to assess the attitude and behaviour of Dutch ENT surgeons and ENT residents towards Evidence Based Medicine. Introduction Evidence Based Medicine is the cornerstone of modern ...
  • Euthanasie van Nederlandse psychiatrische patiënten in 2015-2017 
    Van Veen, S. M.P.; Weerheim, F. W.; Mostert, M.; Van Delden, J. J.M. (Uitgeverij Boom, 2019-04)
    BACKGROUND The Netherlands is one of the few countries in the world that allows euthanasia and assisted suicide (eas) due to psychiatric suffering. METHODS In 2015-2017 the Dutch regional euthanasia review committees ...
  • Individual prediction of psychotherapy outcome in posttraumatic stress disorder using neuroimaging data 
    Zhutovsky, Paul; Thomas, Rajat M.; Olff, Miranda; van Rooij, Sanne J.H.; Kennis, Mitzy; van Wingen, Guido A.; Geuze, Elbert (Nature Publishing Group, 2019-12-01)
    Trauma-focused psychotherapy is the first-line treatment for posttraumatic stress disorder (PTSD) but 30–50% of patients do not benefit sufficiently. We investigated whether structural and resting-state functional magnetic ...
  • The use of 3D laparoscopic imaging systems in surgery: EAES consensus development conference 2018 
    Arezzo, Alberto; Vettoretto, Nereo; Francis, Nader K.; Bonino, Marco Augusto; Curtis, Nathan J.; Amparore, Daniele; Arolfo, Simone; Barberio, Manuel; Boni, Luigi; Brodie, Ronit; Bouvy, Nicole; Cassinotti, Elisa; Carus, Thomas; Checcucci, Enrico; Custers, Petra; Diana, Michele; Jansen, Marilou; Jaspers, Joris; Marom, Gadi; Momose, Kota; Müller-Stich, Beat P.; Nakajima, Kyokazu; Nickel, Felix; Perretta, Silvana; Porpiglia, Francesco; Sánchez-Margallo, Francisco; Sánchez-Margallo, Juan A.; Schijven, Marlies; Silecchia, Gianfranco; Passera, Roberto; Mintz, Yoav (Springer New York, 2019-10-15)
    Background: The use of 3D laparoscopic systems is expanding. The European Association of Endoscopic Surgery (EAES) initiated a consensus development conference with the aim of creating evidence-based statements and ...
  • Development process of a mobile electronic medical record for nurses: A single case study 
    Vossebeld, Danielle M.; Puik, Erik C.N.; Jaspers, Joris E.N.; Schuurmans, Marieke J. (BioMed Central, 2019-01-14)
    Background: With the growing shortage of nurses, labor-saving technology has become more important. In health care practice, however, the fit with innovations is not easy. The aim of this study is to analyze the development ...
  • Visualizing mental representations in schizophrenia patients: A reverse correlation approach 
    Brinkman, Loek; Dotsch, Ron; Zondergeld, Jelmer; Koevoets, Martijn G.J.C.; Aarts, Henk; van Haren, Neeltje E.M. (Elsevier, 2019-09-01)
    Schizophrenia patients have difficulties recognizing emotional states from faces, in particular those with negative valence, with severe consequences for daily life. What do these patients see in their minds eye, when they ...
  • Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology 
    Reichenstein, Irit; Eitan, Chen; Diaz-Garcia, Sandra; Haim, Guy; Magen, Iddo; Siany, Aviad; Hoye, Mariah L; Rivkin, Natali; Olender, Tsviya; Toth, Beata; Ravid, Revital; Mandelbaum, Amitai D; Yanowski, Eran; Liang, Jing; Rymer, Jeffrey K; Levy, Rivka; Beck, Gilad; Ainbinder, Elena; Farhan, Sali M K; Lennox, Kimberly A; Bode, Nicole M; Behlke, Mark A; Möller, Thomas; Saxena, Smita; Moreno, Cristiane A M; Costaguta, Giancarlo; van Eijk, Kristel R; Phatnani, Hemali; Al-Chalabi, Ammar; Başak, A Nazli; van den Berg, Leonard H; Hardiman, Orla; Landers, John E; Mora, Jesus S; Morrison, Karen E; Shaw, Pamela J; Veldink, Jan H; Pfaff, Samuel L; Yizhar, Ofer; Gross, Christina; Brown, Robert H; Ravits, John M; Harms, Matthew B; Miller, Timothy M; Hornstein, Eran (American Association for the Advancement of Science, 2019-12-18)
    Motor neuron-specific microRNA-218 (miR-218) has recently received attention because of its roles in mouse development. However, miR-218 relevance to human motor neuron disease was not yet explored. Here, we demonstrate ...
  • Increased number of T-lymphocytes in post-mortem brain tissue of patients with schizophrenia. 
    Sneeboer, Marjolein A.M.; van Mierlo, Hans C.; Stotijn, Evi; MacIntyre, Donald J.; Smith, Colin; Kahn, René S.; Hol, Elly M.; de Witte, Lot D. (Elsevier, 2019-01-01)
  • Critical Gaps in Understanding the Clinician-Scientist Workforce: Results of an International Expert Meeting 
    International Expert Group on the Clinician–Scientist Workforce (Wolters Kluwer, 2019-10-01)
    Clinician-scientists-health care professionals expert in research and clinical practice-can play a vital role in translating research outcomes to clinical practice. Concerns about the sustainability of the clinician-scientist ...
  • Speaking up, support, control and work engagement of medical residents. A structural equation modelling analysis 
    Voogt, Judith; Taris, Toon W.; van Rensen, Liesbeth; Schneider, M.M.E.; Noordegraaf, M.; van der Schaaf, Marieke (Wiley-Blackwell, 2019-11)
    OBJECTIVES: Medical residents can play key roles in improving health care quality by speaking up and giving suggestions for improvements. However, previous research on speaking up by medical residents has shown that speaking ...
  • Identification of the clinically most relevant postoperative complications after gastrectomy: a population-based cohort study 
    Dutch Upper Gastrointestinal Cancer Audit (DUCA) Group (Springer Japan, 2020-03)
    BACKGROUND: Postoperative complications frequently occur after gastrectomy for gastric cancer and are associated with poor clinical outcomes, such as mortality and reoperations. The aim of study was to identify the clinically ...
  • Evidence for measuring teachers’ core practices 
    van der Schaaf, Marieke; Slof, Bert; Boven, L.; A., Jong, De (Routledge, 2019-10-20)
    Teaching is a complex profession and feedback on teacher practices is needed for teachers’ development. Many instruments are available to measure teacher practices, but little is known about their quality. This systematic ...
  • Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes 
    van Eijk, Maarten; Boosman, René J; Schinkel, Alfred H; Huitema, Alwin D R; Beijnen, Jos H (Springer-Verlag, 2019)
    Enzymes of the cytochrome P450 (CYP) subfamily 3A and 2C play a major role in the metabolism of taxane anticancer agents. While their function in hepatic metabolism of taxanes is well established, expression of these enzymes ...
  • Understanding the Broker Role of Clinician-Scientists: A Realist Review on How They Link Research and Practice 
    Barry, Margot; de Groot, Esther; Baggen, Yvette; Smalbrugge, Martin; Moolenaar, Nienke; Bartelink, Marie Louise E.L.; Damoiseaux, Roger A.M.J.; Scherpbier, Nynke; Kluijtmans, Manon (Wolters Kluwer, 2019-10-01)
    PURPOSE: Clinician-scientists are said to be well placed to connect research and practice, but their broker role has been underexplored. This review sought to gain an understanding of the broker role of clinician-scientists. ...
  • Audio peer feedback to promote deep learning in online education 
    Filius, RM; de Kleijn, RAM; Uijl, SG; Prins, Frans; van Rijen, HVM; Grobbee, DE (Wiley-Blackwell Publishing Ltd, 2019-10)
    We investigated the relation between providing and receiving audio peer feedback with a deep approach to learning within online education. Online students were asked to complete peer feedback assignments. Data through a ...
  • Mimicking the Articular Joint with In Vitro Models 
    Piluso, Susanna; Li, Yang; Abinzano, Florencia; Levato, Riccardo; Moreira Teixeira, Liliana; Karperien, Marcel; Leijten, Jeroen; van Weeren, René; Malda, Jos (Elsevier Limited, 2019-10)
    Treating joint diseases remains a significant clinical challenge. Conventional in vitro cultures and animal models have been helpful, but suffer from limited predictive power for the human response. Advanced models are ...
  • Visible Light Cross-Linking of Gelatin Hydrogels Offers an Enhanced Cell Microenvironment with Improved Light Penetration Depth 
    Lim, Khoon S; Klotz, BJ; Lindberg, Gabriella C J; Melchels, Ferry P W; Hooper, Gary J; Malda, Jos; Gawlitta, Debby; Woodfield, Tim B F (Wiley-VCH Verlag, 2019-06)
    In this study, the cyto-compatibility and cellular functionality of cell-laden gelatin-methacryloyl (Gel-MA) hydrogels fabricated using a set of photo-initiators which absorb in 400-450 nm of the visible light range are ...
  • When observational studies are as helpful as randomized trials: Examples from orthopedic trauma: Examples from orthopedic trauma 
    Beks, R B; Bhashyam, Abhiram R; Houwert, R M; van der Velde, D; van Heijl, M; Smeeing, Dpj; Hietbrink, F; Leenen, L P H; Groenwold, Rhh (Lippincott Williams & Wilkins, 2019-09)
    Randomized controlled trials (RCTs) are often challenging to design in surgical fields and can be misleading when poorly executed. While the prevailing belief is that observational studies on therapeutic efficacy are ...
  • Polytrauma and and High-energy Injury Mechanisms are Associated with Worse Patient-reported Outcomes After Distal Radius Fractures 
    van der Vliet, Q M J; Sweet, A A R; Bhashyam, A R; Ferree, S; van Heijl, M; Houwert, R M; Leenen, L P H; Hietbrink, F (Springer New York, 2019-10)
    BackgroundPatient-reported outcomes (PROs) are increasingly relevant when evaluating the treatment of orthopaedic injuries. Little is known about how PROs may vary in the setting of polytrauma or secondary to high-energy ...