Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

Now showing items 21621-21640 of 40729

Mediation analysis of the alcohol-postmenopausal breast cancer relationship by sex hormones in the EPIC cohort

Assi, Nada; Rinaldi, Sabina; Viallon, Vivian; Dashti, S. Ghazaleh; Dossus, Laure; Fournier, Agnès; Cervenka, Iris; Kvaskoff, Marina; Turzanski-Fortner, Renée; Bergmann, Manuela; Boeing, Heiner; Panico, Salvatore; Ricceri, Fulvio; Palli, Domenico; Tumino, Rosario; Grioni, Sara; Sánchez Pérez, María José; Chirlaque, María Dolores; Bonet, Catalina; Gurrea, Aurelio Barricarte; Amiano Etxezarreta, Pilar; Merino, Susana; Bueno de Mesquita, H. Bas; van Gils, Carla H.; Onland-Moret, Charlotte; Tjønneland, Anne; Overvad, Kim; Trichopoulou, Antonia; Martimianaki, Georgia; Karakatsani, Anna; Key, Tim; Christakoudi, Sofia; Ellingjord-Dale, Merete; Tsilidis, Kostas; Riboli, Elio; Kaaks, Rudolf; Gunter, Marc J.; Ferrari, Pietro (John Wiley & Sons Inc., 2020-02-01)

Alcohol consumption is associated with higher risk of breast cancer (BC); however, the biological mechanisms underlying this association are not fully elucidated, particularly the extent to which this relationship is ...
Trends in risk of limitations in instrumental activities of daily living over age in older persons with and without multiple chronic conditions

Mueller-Schotte, Sigrid; Zuithoff, Nicolaas P A; van der Schouw, Yvonne T; Schuurmans, Marieke J; Bleijenberg, Nienke (Oxford University Press, 2020-01-01)

BACKGROUND: To investigate trends over age by comorbidity status for the risk of limitations in individual activities of daily living for community-living older persons. METHODS: A longitudinal population-based study was ...
MRI phenotypes of the brain are related to future stroke and mortality in patients with manifest arterial disease: The SMART-MR study

Second Manifestations of ARTerial Disease (SMART) Study Group. (SAGE Publications Inc., 2020-02-01)

Neurodegenerative and neurovascular diseases lead to heterogeneous brain abnormalities. A combined analysis of these abnormalities by phenotypes of the brain might give a more accurate representation of the underlying ...
Electrochemotherapy in the head and neck area: an addition to the treatment armamentarium

de Bree, Remco; Wessel, Irene (Lippincott Williams & Wilkins, 2020-04-01)

PURPOSE OF REVIEW: Electrochemotherapy (ECT) is increasingly used in different settings in head and neck cancer patients when conventional treatment options are not available. RECENT FINDINGS: Recent improvements of ...
Target coverage and dose criteria based evaluation of the first clinical 1.5T MR-linac SBRT treatments of lymph node oligometastases compared with conventional CBCT-linac treatment

Winkel, Dennis; Bol, Gijsbert H.; Werensteijn-Honingh, Anita M.; Intven, Martijn P.W.; Eppinga, Wietse S.C.; Hes, Jochem; Snoeren, Louk M.W.; Sikkes, Gonda G.; Gadellaa-van Hooijdonk, Christa G.M.; Raaymakers, Bas W.; Jürgenliemk-Schulz, Ina M.; Kroon, Petra S. (Elsevier Ireland Ltd, 2020-05-01)

Background and purpose: Patients were treated at our institute for single and multiple lymph node oligometastases on the 1.5T MR-linac since August 2018. The superior soft-tissue contrast and additional software features ...
IgA-mediated killing of tumor cells by neutrophils is enhanced by CD47–SIRPA checkpoint inhibition

Treffers, Louise W; Ten Broeke, Toine; Rösner, Thies; Jansen, J H Marco; van Houdt, Michel; Kahle, Steffen; Schornagel, Karin; Verkuijlen, Paul J J H; Prins, Jan M; Franke, Katka; Kuijpers, Taco W; van den Berg, Timo K; Valerius, Thomas; Leusen, Jeanette H W; Matlung, Hanke L (American Association for Cancer Research Inc., 2020-01-01)

Therapeutic monoclonal antibodies (mAb), directed toward either tumor antigens or inhibitory checkpoints on immune cells, are effective in cancer therapy. Increasing evidence suggests that the therapeutic efficacy of these ...
The superior predictive value of 166Ho-scout compared with 99mTc-macroaggregated albumin prior to 166Ho-microspheres radioembolization in patients with liver metastases

Smits, Maarten L J; Dassen, Mathijs G; Prince, Jip F; Braat, Arthur J A T; Beijst, Casper; Bruijnen, Rutger C G; de Jong, Hugo W A M; Lam, Marnix G E H (Springer-Verlag, 2020-04-01)

Purpose: As an alternative to technetium-99m-macroaggregated albumin ( 99mTc-MAA), a scout dose of holmium-166 ( 166Ho) microspheres can be used prior to 166Ho-radioembolization. The use of identical particles for pre-treatment ...
Extended-spectrum beta-lactamase (ESBL)-producing and non-ESBL-producing Escherichia coli isolates causing bacteremia in the Netherlands (2014 - 2016) differ in clonal distribution, antimicrobial resistance gene and virulence gene content

van Hout, Denise; Verschuuren, Tess D; Bruijning-Verhagen, Patricia C J; Bosch, Thijs; Schürch, Anita C; Willems, Rob J L; Bonten, Marc J M; Kluytmans, Jan A J W (Public Library of Science, 2020-01-01)

Background Knowledge on the molecular epidemiology of Escherichia coli causing E. coli bacteremia (ECB) in the Netherlands is mostly based on extended-spectrum beta-lactamase-producing E. coli (ESBL-Ec). We determined ...
Nanocarrier-based drug combination therapy for glioblastoma

Zhao, Mengnan; van Straten, Demian; Broekman, Marike L. D.; Preat, Veronique; Schiffelers, Raymond M. (Ivyspring International Publisher, 2020-01-01)

The current achievements in treating glioblastoma (GBM) patients are not sufficient because many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem cells, drug efflux pumps and DNA damage ...
Sex-specific thoracic aortic dimensions and clinical implications

Groepenhoff, Floor; den Ruijter, Hester M (BMJ Publishing Group, 2020-01-01)
Feasibility of extended chemoradiotherapy plus surgery for patients with cT4b esophageal carcinoma

Anderegg, Martinus C J; Ruurda, Jelle P; Gisbertz, Suzanne S; Blom, Rachel L G M; Sosef, Meindert N; Wijnhoven, Bas P L; Hulshof, Maarten C C M; Bergman, Jacques J G H M; van Laarhoven, Hanneke W M; van Berge Henegouwen, Mark I (W.B. Saunders Ltd, 2020-04)

BACKGROUND: Treatment of cT4b esophageal carcinoma usually consists of definitive chemoradiotherapy (dCRT). However, outcome after dCRT in these patients is poor. Whether surgery should have a place in the treatment of ...
Predictors for Autoimmune Cytopenias after Allogeneic Hematopoietic Cell Transplantation in Children

Szanto, Celina L; Langenhorst, Jurgen; de Koning, Coco; Nierkens, Stefan; Bierings, Marc; Huitema, Alwin D R; Lindemans, Caroline A; Boelens, Jaap J (Elsevier, 2020-01)

Development of autoimmune cytopenia (AIC) after allogeneic hematopoietic cell transplantation (HCT) is a serious complication requiring urgent intensification of immunosuppressive therapy. The pathophysiology and predictors ...
Unravelling complexities of the subsolid pulmonary nodule—detection, characterization, natural history, monitoring and (future) patient management

Pompe, Esther; De Jong, Pim A.; Mohamed Hoesein, Firdaus A.A. (Pioneer Bioscience Publishing Company (PBPC), 2019-05)

Lung cancer is a major cause of death worldwide with an estimated 1.8 million new diagnoses and 1.6 million deaths annually (1). The five-year survival rate is poor as symptoms usually occur in an advanced stage of cancer ...
Minimally Invasive Esophagectomy

van der Sluis, Pieter Christiaan; Schizas, Dimitrios; Liakakos, Theodore; van Hillegersberg, Richard (S. Karger AG, 2020-03-01)

Minimally invasive esophagectomy (MIE) was introduced in the 1990s with the aim to decrease the rate of respiratory complications associated with thoracotomy, along with the benefits of reduced morbidity and a quicker ...
Microbleeds colocalize with enlarged juxtacortical perivascular spaces in amnestic mild cognitive impairment and early Alzheimer's disease: A 7 Tesla MRI study

Bouvy, Willem H; van Veluw, Susanne J; Kuijf, Hugo J; Zwanenburg, Jaco Jm; Kappelle, Jaap L; Luijten, Peter R; Koek, Huiberdina L; Geerlings, Mirjam I; Biessels, Geert J; Utrecht Vascular Cognitive Impairment (VCI) Study group (SAGE Publications Inc., 2020-04-01)

MRI-visible perivascular spaces (PVS) in the semioval centre are associated with cerebral amyloid angiopathy (CAA), but it is unknown if PVS co-localize with MRI markers of CAA. To examine this, we assessed the topographical ...
Sex differences in cardiovascular risk management for people with diabetes in primary care: a cross-sectional study.

de Jong, Marit; Vos, Rimke; Bots, Michael L; De Ritter, Rianneke; van der Kallen, Carla J H; Sep, Simone J S; Stehouwer, Coen DA; Woodward, Mark; Peters, Sanne (Royal College of General Practitioners, 2019-07-23)

BACKGROUND: Diabetes is a stronger risk factor for cardiovascular complications in women than men. AIM: To evaluate whether there are sex differences in cardiovascular risk management in patients with diabetes in primary ...
Untargeted metabolomics for metabolic diagnostic screening with automated data interpretation using a knowledge-based algorithm

Haijes, Hanneke A.; van der Ham, Maria; Prinsen, Hubertus C.M.T.; Broeks, Melissa H.; van Hasselt, Peter M.; de Sain-Van der Velden, Monique G.M.; Verhoeven-Duif, Nanda M.; Jans, Judith J.M. (Multidisciplinary Digital Publishing Institute (MDPI), 2020-02-01)

Untargeted metabolomics may become a standard approach to address diagnostic requests, but, at present, data interpretation is very labor-intensive. To facilitate its implementation in metabolic diagnostic screening, we ...
Plasmids shaped the recent emergence of the major nosocomial pathogen Enterococcus faecium

Arredondo-Alonso, S.; Top, J.; McNally, A.; Puranen, S.; Pesonen, M.; Pensar, J.; Marttinen, P.; Braat, J. C.; Rogers, M. R.C.; van Schaik, W.; Kaski, S.; Willems, R. J.L.; Corander, J.; Schürch, A. C. (American Society for Microbiology, 2020-02-11)

Enterococcus faecium is a gut commensal of humans and animals but is also listed on the WHO global priority list of multidrug-resistant pathogens. Many of its antibiotic resistance traits reside on plasmids and have the ...
Erratum: Sawtooth potassium and hemoglobin results (Clinical Chemistry (2019) 65 (1463–1464) DOI: 10.1373/clinchem.2019.304394)

Musson, Ruben E.A.; Huisman, Albert; Nonkes, Lourens J.P.; Kemperman, Hans (Oxford University Press, 2020-01-01)

CASE DESCRIPTION A 5-year-old boy was admitted with dyspnea, fever, night sweats, and unexplained bruising. Radiography revealed several pulmonary consolidations, and laboratory investigations showed marked hyperleukocytosis ...
Neuroblastoma between 1990 and 2014 in the Netherlands: Increased incidence and improved survival of high-risk neuroblastoma

Tas, M. L.; Reedijk, A. M.J.; Karim-Kos, H. E.; Kremer, L. C.M.; van de Ven, C. P.; Dierselhuis, M. P.; van Eijkelenburg, N. K.A.; van Grotel, M.; Kraal, K. C.J.M.; Peek, A. M.L.; Coebergh, J. W.W.; Janssens, G. O.R.; de Keizer, B.; de Krijger, R. R.; Pieters, R.; Tygtat, G. A.M.; van Noesel, M. M. (Elsevier Limited, 2020-01-01)

PURPOSE: Long-term trends in neuroblastoma incidence and survival in unscreened populations are unknown. We explored trends in incidence, stage at diagnosis, treatment and survival of neuroblastoma in the Netherlands from ...

Now showing items 21621-21640 of 40729