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Gaining Control: Neural Basis of Proactive Inhibition

Pas, Pascal (Utrecht University, 2021-12-16)

The goal of this thesis was to investigate the neural underpinnings of proactive inhibition. Via a number of separate experiments, the key regions associated with this process have been identified. Furthermore, functional ...
Learning in (inter)action: Implicit and explicit EBM learning processes at the GP workplace

Welink, Lisanne Stefanie (Utrecht University, 2021-12-02)

The main goal of this thesis is to gain a better understanding of current evidence-based medicine (EBM) learning processes at the general practice (GP) workplace. EBM is defined as combining clinical expertise, the preferences ...
Participation after stroke: Towards personalized care

Graaf, Joris Anton de (Utrecht University, 2021-11-30)

Stroke is one of the leading causes of death and disability worldwide. The incidence of stroke and the post-stroke survival rates have increased over the last decades, resulting in more people that have to deal with the ...
To repair the infarcted heart

Peters, Maria Catharina (Utrecht University, 2021-11-25)

Many advances have been made in moving towards repairing the infarcted ischemic heart, but clinical translation remains challenging. It is unlikely that the solution of repairing the heart lies in a single factor targeting ...
Go big or go home: Translational approaches to target ischemic heart failure

Demkes, Evelyne Jeannette (Utrecht University, 2021-11-18)

Despite improved prevention, diagnosis and treatment methods, heart disease caused by lack of oxygen remains the leading cause of morbidity and mortality worldwide. This thesis focuses on new interventions and treatment ...
Gram-negative infections – Burden, Antibiotic Resistance and Empiric Treatment

Deelen, Jan Willem Timotëus (Utrecht University, 2020-12-11)
Closure of the interatrial septum: should we do it?

Snijder, Roel Jaap Robbert (Utrecht University, 2020-12-10)

This thesis reports the efficacy and safety of different devices in percutaneous patent foramen ovale- (PFO) and atrial septal defect (ASD) closure during long-term follow-up. A PFO is a tunnel-like opening between the ...
Personalized radioembolization for colorectal cancer patients with liver metastases

Roekel, Jacoba van (Utrecht University, 2020-11-24)
Unexplained symptoms in primary care : an integrated physical and psychological approach

Westrienen, Paula Elisabeth van (Utrecht University, 2020-11-17)

Medically unexplained physical symptoms (MUPS) are an important health problem in primary care, with a spectrum from mild to chronic. The burden of chronic MUPS is substantial for patients, health care professionals, and ...
Cost-effectiveness of selective cardiometabolic disease prevention in primary care

Stol, Daphne Marije (Utrecht University, 2020-09-22)

Cost-effective preventive strategies are needed to anticipate the rising burden of cardiometabolic diseases (CMD), including cardiovascular disease, diabetes type 2 and chronic kidney disease. The guideline ‘the prevention ...
A matter of life or death: targeting MCL-1 in multiple myeloma

Slomp, Anne (Utrecht University, 2020-09-09)
Pre-hospital Trauma Systems : Pushing the Boundaries of Precision Medicine

Sluijs, Rogier van der (Utrecht University, 2020-07-08)
Epigenetic Morphology and Classification of Neuroendocrine Tumors

Hackeng, Wenzel Maximilian (Utrecht University, 2022-01-20)

Neuroendocrine tumors (NETs) are rare tumors, most commonly encountered in the small intestine, pancreas and lung. The mechanisms of NET tumorigenesis are not completely understood. Furthermore, it is challenging to predict ...
Rehabilitation of midportion Achilles tendinopathy in athletes: Loading programmes, hip muscle function and return to sport

Habets, Bas (Utrecht University, 2021-12-20)

Midportion Achilles tendinopathy is a common injury of the lower extremity, most prevalent in sports involving running and jumping. The injury may cause severe limitations of sports participation and treatment is often ...
Risk Stratification for Adverse Events after Carotid Endarterectomy

Timmerman, Nathalie (Utrecht University, 2021-10-26)

Patients with symptomatic carotid artery stenosis have a high risk of future ipsilateral cerebrovascular events and this risk can be effectively reduced by a surgival removel of the carotid plaque (carotid endarterectomy, ...
Practical applications of whole genome sequencing for reservoir epidemiology, molecular surveillance, and antimicrobial susceptibility testing of extended-spectrum ß-lactamase producing Escherichia coli

Verschuuren, Tess Daniëlle (Utrecht University, 2021-11-04)

The World Health Organization declared antimicrobial resistance (AMR) one of the top 10 public health threats facing humanity. In Europe, ESBL-producing Escherichia coli (ESBL-Ec) is the most important cause of AMR ...
Advancing management of aortic aneurysm disease

Guerre, Livia Eugénie Valerie Marie de (Utrecht University, 2021-10-29)

Part I focusses on the value of aortic aneurysm repair database research. As many administrative data and quality improvement registries are widely available and easily accessible, an understanding of the appropriate use ...
How complement forms pores in bacterial membranes : A complex assembly

Doorduijn, Dennis Jeroen (Utrecht University, 2021-11-16)

Bacteria that cause infections pose a great threat to global human health. Because some bacteria are becoming more and more resistant to our current antibiotics, we are in dire need of alternatives to treat bacterial ...
Modelling multi-strain pathogen dynamics: Inferring between-strain interactions and assessing vaccine-induced replacement

Man, Yi Sum Irene (Utrecht University, 2021-11-16)

Pathogenic bacteria and viruses often consist of multiple genetic variants, also called strains. Despite their differences, strains of pathogens may sometimes affect one another during transmission dynamics and disease ...
Magnetic resonance imaging to characterize chronic inflammatory neuropathies

Rosmalen, Marieke Helena Johanna van (Utrecht University, 2021-11-04)

This thesis focuses on the characteristics of chronic inflammatory demyelinating polyneuropathy (CIDP) and multifocal motor neuropathy (MMN) evaluated in multiple MRI-studies. Possible improvements of assessment of brachial ...

Now showing items 21121-21140 of 40729