Implementations of potentially transformative eHealth technologies are currently underway internationally, often with significant impact on national expenditure. Such large-scale efforts and expenditures have been justified ...

Cerebrovascular disease is a major cause of cognitive impairment and dementia, either by itself or in combination with Alzheimer’s disease. The contribution of vascular brain injury to cognitive impairment and dementia is ...

Since the rise of DNA sequencing technologies, it became apparent that the majority of diseases in humankind have – at least partly – a genetic origin.Many types of Epilepsy are also caused by DNA mutations. A DNA mutation ...

Much has been learned on mental disorder in the past decades, but this has hardly led to better treatments of mental disorder. One reason may be that our dominant ontology of mental disorder is incorrect. This formed the ...

Brain development during pregnancy is characterized by tremendous brain growth and the construction of connections between communicating brain regions (brain networks). This makes the fetal period essential for normal ...

In recent years, there have been several advancements in the management of patients with cardiovascular diseases, including thoracic aortic aneurysm and dissection, aortic valve stenosis (AS), congenital cardiac abnormalities, ...

Sudden cardiac death is a major problem in the Western world. In young people, sudden cardiac arrest is often caused by ventricular fibrillation (VF). In most cases of VF, an underlying cause is found. However, in a small ...

Alzheimer’s disease causes between 60% and 70% of all cases of dementia. Astrocytes maintain water, ion- and neurotransmitter homeostasis in a healthy brain, and they become reactive during Alzheimer’s disease. Astrocyte ...

Genome engineering technologies have been in a rapid series of development over the past decade. The development of CRISPR/Cas9 as an efficient and easy to reprogram genome editing tool has revolutionized biological sciences. ...

The prevalence of multimorbidity and polypharmacy is increasing in the ageing population, and both are important risk factors for drug-related harm, such as drug-related hospital admissions. Previous studies have reported ...