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UMC Repository: Recent submissions

  • Kidwai, Sarah; Rojas-Velazquez, David; Kožinec, Dora; Vaišvilas, Lukas; Perez-Pardo, Paula; Lopez-Rincon, Alejandro (HAL open science, 2023-05-01)
    Inflammatory Bowel Disease (IBD) refers to two conditions: ulcerative colitis (UC) and Crohn disease (CD) [1]. IBD has a range of clinical symptoms including abdominal pain, diarrhoea, weight loss, constipation, and fatigue ...
  • Lopez-Rincon, Alejandro; Roozendaal, Daphne S.; Spierenburg, Hilde M.; Holm, Asta L.; Metcalf, Renee; Perez-Pardo, Paula; Kraneveld, Aletta D.; Tonda, Alberto (Springer International Publishing, 2021)
    For several medical treatments, it is possible to observe transcriptional variations in gene expressions between responders and non-responders. Modelling the correlation between such variations and the patient's response ...
  • Hackett, Sara; Asselen, Bram van; Philippens, Marielle; Woodings, Simon (Springer, 2022-10-12)
    The excellent soft-tissue contrast of magnetic resonance (MR) images, and the speed and frequency with which the patient can be imaged, allow clear visualization of the target and nearby organs at risk at multiple time ...
  • Lefferts, Juliet W.; Boersma, Vera; Hagemeijer, Marne C.; Hajo, Karima; Beekman, Jeffrey M.; Splinter, Erik (Humana Press Inc., 2023)
    Targeted locus amplification (TLA) allows for the detection of all genetic variation (including structural variation) in a genomic region of interest. As TLA is based on proximity ligation, variants can be linked to each ...
  • van Hasselt, Peter M.; Clayton, Peter T.; Houwen, Roderick H.J. (Springer Berlin Heidelberg, 2022-06-24)
    Metals, as well as selenium, are indispensable elements in cell biology. They function as cofactors for many specific proteins and are involved in all major metabolic pathways. The number of recognised IEM involving the ...
  • Vos, Iris; Bhat, Ishaan; Velthuis, Birgitta; Ruigrok, Ynte; Kuijf, Hugo (2023-04-05)
    Miscalibration of deep neural networks (DNNs) can lead to unreliable predictions and hinder their use in clinical decision-making. This miscalibration is often caused by overconfident probability estimates. Calibration ...
  • Michalsen, Andrej; Mer, Mervyn; Hoff, RG; Janssens, Uwe; Sadovnikoff, Nicolas (Springer, 2023-07-20)
    A simple maxim for clinical ethics could read, “meaning well and doing good,” or “making treatment choices that integrate sensible medical options with the individual patient’s wishes and values.” With respect to this goal, ...
  • van der Zee, David C.; Lindeboom, Maud Y.A.; Tytgat, Stefaan H.A. (Springer, 2022-12-01)
    Many consider the repair of esophageal atresia and tracheoesophageal fistula the quintessential pediatric surgical operation. While the operation for repair of the most common types is certainly elegant and gratifying, ...
  • Hermes, Dora; Siero, Jeroen C.W. (Springer International Publishing, 2023-01-01)
    Human brain activity can be measured in many ways, providing different views into its functions. Common measurements of human brain function, such as functional MRI (fMRI) and electroencephalography (EEG), are often ...
  • Alexandridis, Dionysis; Bakkes, Sander C.J.; Nijhof, Sanne L.; Van De Putte, Elise; Veltkamp, Remco C. (Association for Computing Machinery, Inc, 2023-04-12)
    We present the first experiments from a pilot study with Ruby's Mission, an applied gaming intervention for reducing feelings of loneliness in children with a chronic illness. Based on a previously performed literature ...
  • Broomé, Michael; Carlsson, Marcus; Frieberg, Petter; Hakacova, Nina; Liuba, Petru; Donker, Dirk W. (Springer International Publishing, 2022-01-01)
    The variable presentation of clinical disease in pediatric patients with congenital and acquired heart disease makes standardized care challenging. This is further enforced by the ongoing growth and remodeling of the heart ...
  • Gallagher, Timothy; Slof, Bert; van der Schaaf, Marieke; Toyoda, Ryo; Tehreem, Yusra; Fracaro, Sofia Garcia; Kester, Liesbeth (Springer Science and Business Media Deutschland GmbH, 2022-11)
    This study uses log-file data to investigates how chemical process plant employees interact and engage with two distinct learning analytics dashboard designs, which are implemented in a virtual reality simulation-based ...
  • van der Kamp, Hetty (NVK, 2023-03-14)
  • van de Kamp, Judith (de Gruyter, 2023-03-06)
    This chapter, based on extensive ethnographic research in a rural hospital in Northwest Cameroon, contributes to scholarly debates about the value of International Medical Electives (IMEs). It aims at filling the knowledge ...
  • Wielenga, Vera H.; Dijkhuizen, Rick M.; Van der Toorn, Annette (Humana New YorkHumana New York, 2023-01-31)
    Magnetic resonance imaging (MRI) allows noninvasive and non-destructive imaging of brain tissue. More specifically, the status of white matter fibers can be measured with diffusion-weighted MRI, enabling assessment of ...
  • Bosman, Sabine L.; Sonnen, Katharina F. (ElsevierAcademic Press Inc., 2022)
    Tight spatiotemporal control of cellular behavior and cell fate decisions is paramount to the formation of multicellular organisms during embryonic development. Intercellular communication via signaling pathways mediates ...
  • Timmins, Kimberley M.; Kamphuis, Maarten J.; Vos, Iris N.; Velthuis, Birgitta K.; Schaaf, Irene C.van der; Kuijf, Hugo J. (SpringerSpringer, 2022-12-17)
    The growth of unruptured intracranial aneurysms (UIAs) is a predictor of rupture. Therefore, for further imaging surveillance and treatment planning, it is important to be able to predict if an UIA is likely to grow based ...
  • Keijzer-Veen, Mandy; Dorresteijn, Eiske M. (2022-11-01)
  • Koster-Kamphuis, Linda; Lilien, Marc; Groothoff, Jaap W (NVK, 2022-11-01)
  • Cornelissen, E.A.M.; Lilien, Marc (2022-11-01)