Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

Now showing items 20221-20240 of 40729

Single- versus double-layer closure of the caesarean (uterine) scar in the prevention of gynaecological symptoms in relation to niche development - the 2Close study: a multicentre randomised controlled trial

Stegwee, S I; Jordans, I P M; van der Voet, L F; Bongers, M Y; de Groot, C J M; Lambalk, C B; de Leeuw, R A; Hehenkamp, W J K; van de Ven, P M; Bosmans, J E; Pajkrt, E; Bakkum, E A; Radder, C M; Hemelaar, M; van Baal, W M; Visser, H; van Laar, J O E H; van Vliet, H A A M; Rijnders, R J P; Sueters, M; Janssen, C A H; Hermes, W; Feitsma, A H; Kapiteijn, K; Scheepers, H C J; Langenveld, J; de Boer, K; Coppus, S F P J; Schippers, D H; Oei, A L M; Kaplan, M; Papatsonis, D N M; de Vleeschouwer, L H M; van Beek, E; Bekker, M N; Huisjes, A J M; Meijer, W J; Deurloo, K L; Boormans, E M A; van Eijndhoven, H W F; Huirne, J A F (BioMed Central, 2019-03-04)

BACKGROUND: Double-layer compared to single-layer closure of the uterus after a caesarean section (CS) leads to a thicker myometrial layer at the site of the CS scar, also called residual myometrium thickness (RMT). It ...
Views and preferences of medical professionals and pregnant women about a novel primary prevention intervention for hypertensive disorders of pregnancy: a qualitative study

Vestering, A; Bekker, M N; Grobbee, D E; van der Graaf, R; Franx, A; Crombag, N M T; Browne, J L (BioMed Central Ltd., 2019-05-02)

BACKGROUND: Calcium and low-dose aspirin are two potential approaches for primary prevention of hypertensive disorders of pregnancy (HDP). This study aimed to explore the acceptability, views and preferences of pregnant ...
Treatment of older patients with immune checkpoint inhibitors in routine clinical care as compared to inclusion in pivotal registration trials

Crombag, Marie-Rose B S; Haanen, John B A G; Baas, Paul; Beijnen, Jos H; Huitema, Alwin D R (Elsevier, 2020-04-01)
Decreasing Trends in Intestinal Resection and Re-Resection in Crohn's Disease: A Nationwide Cohort Study

Oldenburg, Bas; Erler, Nicole S; Dutch Initiative on Crohnʼs and Colitis (ICC) (Lippincott Williams & Wilkins, 2021-03)

OBJECTIVE: To assess time trends in intestinal resection and re-resection in Crohn's disease (CD) patients. SUMMARY OF BACKGROUND DATA: CD treatment has changed considerably over the past decades. The effect of these ...
Monitoring a Combination of Calprotectin and Infliximab Identifies Patients With Mucosal Healing of Crohn's Disease

Dreesen, Erwin; Baert, Filip; Laharie, David; Bossuyt, Peter; Bouhnik, Yoram; Buisson, Anthony; Lambrecht, Guy; Louis, Edouard; Oldenburg, Bas; Pariente, Benjamin; Pierik, Marieke; van der Woude, C Janneke; D'Haens, Geert; Vermeire, Séverine; Gils, Ann (W.B. Saunders, 2020-03)

BACKGROUND & AIMS: In the TAILORIX trial, no benefit could be shown by infliximab dose escalation based on pharmacokinetic (infliximab serum concentrations) and pharmacodynamic (biomarkers and symptoms) monitoring compared ...
Wheelchair Mobility Confidence Scale for Dutch youth using a manual wheelchair

Sol, M. E.; Bloemen, M. A.T.; Verschuren, O.; Rushton, P. W.; Visser-Meily, J. M.A.; de Groot, J. F. (Taylor and Francis Ltd., 2020-07)

Purpose: The objective of this study was to develop a questionnaire to assess confidence in wheelchair mobility in Dutch youth (WheelCon-Mobility Dutch Youth). Methods: (1) A forward–backward translation process was used ...
Sports participation, physical activity, and health-related fitness in youth with chronic diseases or physical disabilities: The health in adapted youth sports study

Lankhorst, Kristel; Takken, Tim; Zwinkels, Maremka; van Gaalen, Leendert; Velde, Saskia te; Backx, Frank; Verschuren, Olaf; Wittink, Harriet; de Groot, Janke (NSCA National Strength and Conditioning Association, 2021-08-01)

ABSTRACT: Lankhorst, K, Takken, T, Zwinkels, M, van Gaalen, L, Velde, St, Backx, F, Verschuren, O, Wittink, H, and de Groot, J. Sports participation, physical activity, and health-related fitness in youth with chronic ...
Reducing variability in along-tract analysis with diffusion profile realignment

St-Jean, S; Chamberland, Maxime; Leemans, Alexander; Viergever, MA (Academic Press Inc., 2019-10-01)

Diffusion weighted magnetic resonance imaging (dMRI) provides a non invasive virtual reconstruction of the brain's white matter structures through tractography. Analyzing dMRI measures along the trajectory of white matter ...
Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (Nature Genetics, (2018), 50, 4, (524-537), 10.1038/s41588-018-0058-3)

AFGen Consortium (Nature Research, 2019-07)

In the HTML version of this article initially published, the author groups ‘AFGen Consortium’, ‘Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium’, ‘International Genomics of Blood Pressure ...
The Potential of Stem Cell Therapy to Repair White Matter Injury in Preterm Infants: Lessons Learned From Experimental Models

Vaes, Josine E G; Vink, Marit A; de Theije, Caroline G M; Hoebeek, Freek E; Benders, Manon J N L; Nijboer, Cora H A (Frontiers Research Foundation, 2019-01-01)

Diffuse white matter injury (dWMI) is a major cause of morbidity in the extremely preterm born infant leading to life-long neurological impairments, including deficits in cognitive, motor, sensory, psychological, and ...
Daytime urinary incontinence in children and adolescents

Leppink, AJ; Schroeder, RPJ; van de Putte, EM; de Jong, TPVM; Schappin, R (Elsevier, 2019-07)

Daytime urinary incontinence is common in the paediatric population and affects approximately 7-10% of children (aged 5-13 years). Several subtypes of daytime incontinence, which are classified according to their relation ...
Cumulative live birth rates in low-prognosis women

OPTIMIST study group (Oxford University Press, 2019-06-01)

STUDY QUESTION: Do cumulative live birth rates (CLBRs) over multiple IVF/ICSI cycles confirm the low prognosis in women stratified according to the POSEIDON criteria? SUMMARY ANSWER: The CLBR of low-prognosis women is ~56% ...
Natural course of scoliosis and lifetime risk of scoliosis surgery in spinal muscular atrophy

Wijngaarde, Camiel A.; Brink, Rob C.; de Kort, Floor A.S.; Stam, Marloes; Otto, Louise A.M.; Asselman, Fay Lynn; Bartels, Bart; van Eijk, Ruben P.A.; Sombroek, Joyce; Cuppen, Inge; Verhoef, Marjolein; van den Berg, Leonard H.; Wadman, Renske I.; Castelein, René M.; van der Pol, W. Ludo (Lippincott Williams & Wilkins, 2019-07-09)

OBJECTIVE: To investigate the natural course of scoliosis and to estimate lifetime probability of scoliosis surgery in spinal muscular atrophy (SMA). METHODS: We analyzed cross-sectional data from 283 patients from our ...
Sequential co-enrolment in randomised trials in neonatal intensive care medicine

Yoder, Whitney; Groenendaal, Floris; Onland, Wes; van Oploo, Anna; Rietbergen, Charlotte; Groenwold, Rolf (BMJ Publishing Group, 2020-03)

In many medical research settings, such as the neonatal intensive care unit, the number of patients who are eligible for a randomised clinical trial is relatively small and recruiting a sufficient number of patients into ...
The use of corticosteroids does not influence CD4+ lymphocyte recovery in HIV-infected patients with advanced immunodeficiency

van Welzen, Berend J; de Vries, Tamar I; Arends, Joop E; Mudrikova, Tania; Hoepelman, Andy I M (Routledge, 2020-06-02)

Corticosteroids inhibit HIV-related immune activation and seem to have a mild favorable effect on immunological recovery in patients with CD4+ counts ≥200 cells/mm3. Data in patients with advanced immunodeficiency are ...
Health-related quality of life after interval cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with stage III ovarian cancer

Koole, S N; Kieffer, J M; K Sikorska; Schagen van Leeuwen, J H; Schreuder, H W R; Hermans, R H; de Hingh, I H; van der Velden, J; Arts, H J; van Ham, M A P C; Aalbers, A G; Verwaal, V J; Van de Vijver, K K; Sonke, G S; van Driel, W J; Aaronson, N K (W.B. Saunders Ltd, 2021-01)

INTRODUCTION: The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery (CRS) improves recurrence-free (RFS) and overall survival (OS) in patients with FIGO stage III ovarian cancer. ...
A Common Genetic Variation in Langerin (CD207) Compromises Cellular Uptake of Staphylococcus aureus

van Dalen, Rob; Fuchsberger, Felix F.; Rademacher, Christoph; van Strijp, Jos A. G.; van Sorge, Nina M. (S. Karger AG, 2020-02-01)

Langerhans cells are key sentinel cells of the skin and mucosal lining. They sense microorganisms through their repertoire of pattern-recognition receptors to mount and direct appropriate immune responses. We recently ...
Hyperthermia-triggered release of hypoxic cell radiosensitizers from temperature-sensitive liposomes improves radiotherapy efficacy in vitro

Sadeghi, Negar; Kok, Robbert Jan; Bos, Clemens; Zandvliet, Maurice; Geerts, Willie J C; Storm, Gert; Moonen, Chrit T W; Lammers, Twan; Deckers, Roel (IOP Publishing Ltd., 2019-04-12)

Hypoxia is a characteristic feature of solid tumors and an important cause of resistance to radiotherapy. Hypoxic cell radiosensitizers have been shown to increase radiotherapy efficacy, but dose-limiting side effects ...
Increased intra-articular granzyme M may trigger local IFN-λ1/IL-29 response in rheumatoid arthritis

Shan, L; van den Hoogen, LL; Meeldijk, J; Kok, HM; Jongeneel, Lieneke H.; Boes, ML; Wenink, Mark; Hack, Erik; Radstake, TRDJ; van Roon, Joel A.G.; Bovenschen, AN (Clinical and Experimental Rheumatology S.A.S., 2020-03)

Objective Granzymes are serine proteases involved in eliminating tumour cells and virally infected cells. In addition, extracellular granzyme levels are elevated in inflammatory conditions, including several types of ...
Neurodevelopmental Outcomes in Preterm Infants with White Matter Injury Using a New MRI Classification

Martinez-Biarge, Miriam; Groenendaal, Floris; Kersbergen, Karina J; Benders, Manon J N L; Foti, Francesca; van Haastert, Ingrid C; Cowan, Frances M; de Vries, Linda S (S. Karger AG, 2019-10-01)

Objective: The aim of this study was to evaluate whether a new MRI scoring system for preterm non-haemorrhagic white matter injury (WMI), derived from the analysis of the natural evolution of WMI throughout the neonatal ...

Now showing items 20221-20240 of 40729