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Now showing items 19821-19840 of 40729

Oral sex is associated with reduced incidence of recurrent miscarriage

Meuleman, T.; Baden, N.; Haasnoot, G. W.; Wagner, M. M.; Dekkers, O. M.; le Cessie, S.; Picavet, C.; van Lith, J. M.M.; Claas, F. H.J.; Bloemenkamp, K. W.M. (Elsevier Ireland Ltd, 2019-06-01)

A possible way of immunomodulation of the maternal immune system before pregnancy would be exposure to paternal antigens via seminal fluid to oral mucosa. We hypothesized that women with recurrent miscarriage have had less ...
The Predictive Value of Low Muscle Mass as Measured on CT Scans for Postoperative Complications and Mortality in Gastric Cancer Patients: A Systematic Review and Meta-Analysis

Borggreve, Alicia S; den Boer, Robin B; van Boxel, Gijs I; de Jong, Pim A; Veldhuis, Wouter B; Steenhagen, Elles; van Hillegersberg, Richard; Ruurda, Jelle P (Multidisciplinary Digital Publishing Institute (MDPI), 2020-01-11)

Risk assessment is relevant to predict outcomes in patients with gastric cancer. This systematic review aimed to investigate the predictive value of low muscle mass for postoperative complications in gastric cancer patients. ...
Is arterial stiffness in the carotid artery associated with choroidal thinning in patients with pseudoxanthoma elasticum or controls?

Risseeuw, Sara; Bartstra, Jonas; Ossewaarde-van Norel, Jeannette; Geurts, Lennart J; Li, Catherina H Z; Imhof, Saskia M; Spiering, Wilko; de Jong, Pim A; van Leeuwen, Redmer (Wiley-Blackwell, 2020-08)

Purpose: Patients with pseudoxanthoma elasticum (PXE) develop calcification of Bruch's membrane (BM) and choroidal thinning, as well as calcification of intracranial arteries, leading to arterial stiffness. We investigated ...
Mucus plugging, air trapping, and bronchiectasis are important outcome measures in assessing progressive childhood cystic fibrosis lung disease

Robinson, Terry E; Goris, Michael L; Moss, Richard B; Tian, Lu; Kan, Peiyi; Yilma, Mignote; McCoy, Karen S; Newman, Beverley; de Jong, Pim A; Long, Frederick R; Brody, Alan S; Behrje, Rhett; Yates, Denise P; Cornfield, David N (John Wiley & Sons Inc., 2020-04-01)

OBJECTIVE: To determine which outcome measures could detect early progression of disease in school-age children with mild cystic fibrosis (CF) lung disease over a two-year time interval utilizing chest computed tomography ...
Vascular uptake on F-18-sodium fluoride positron emission tomography: precursor of vascular calcification?: precursor of vascular calcification?

den Harder, Annemarie M; Wolterink, Jelmer M; Bartstra, Jonas W; Spiering, Wilko; Zwakenberg, Sabine R; Beulens, Joline W; Slart, Riemer H J A; Luurtsema, Gert; Mali, Willem P; de Jong, Pim A (Springer New York, 2021-10)

Background: Microcalcifications cannot be identified with the present resolution of CT; however, 18F-sodium fluoride ( 18F-NaF) positron emission tomography (PET) imaging has been proposed for non-invasive identification ...
Advancing interdisciplinary research in head and neck cancer through a multicenter longitudinal prospective cohort study: the NETherlands QUality of life and BIomedical Cohort (NET-QUBIC) data warehouse and biobank

Verdonck-de Leeuw, I M; Jansen, F; Brakenhoff, R H; Langendijk, J A; Takes, R; Terhaard, C H J; Baatenburg de Jong, R J; Smit, J H; Leemans, C R (BioMed Central, 2019-08-05)

BACKGROUND: Worldwide, over 500,000 people are diagnosed with head and neck cancer each year, a disease with major impact on life expectancy and quality of life. The purpose of the Netherlands Quality of life and Biomedical ...
Multiparametric MRI Tumor Probability Model for the Detection of Locally Recurrent Prostate Cancer After Radiation Therapy: Pathologic Validation and Comparison With Manual Tumor Delineations

Fernandes, Catarina Dinis; Simoes, Rita; Ghobadi, Ghazaleh; Heijmink, Stijn W. T. P. J.; Schoots, Ivo G.; de Jong, Jeroen; Walraven, Iris; van der Poel, Henk G.; van Houdt, Petra J.; Smolic, Milena; Pos, Floris J.; van der Heide, Uulke A. (Elsevier, 2019-09-01)

Purpose: Focal salvage treatments of recurrent prostate cancer (PCa) after radiation therapy require accurate delineation of the target volume. Magnetic resonance imaging (MRI) is used for this purpose; however, radiation ...
Effect of mechanical insufflation-exsufflation in children with neuromuscular weakness

Veldhoen, Esther S.; Verweij-van den Oudenrijn, Laura P.; Ros, Leandra A.; Hulzebos, Erik H.; Papazova, Diana A.; van der Ent, Cornelis K.; van der Pol, Ludo W.; Nijman, Joppe; Wösten-van Asperen, Roelie M. (John Wiley & Sons Inc., 2020-02-01)

Introduction: Children with neuromuscular diseases develop cough impairment. Airway clearance techniques (ACTs) may help to prevent recurrent respiratory tract infections (RTIs). A commonly used ACT is mechanical ...
Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy

Logtenberg, Meike E W; Jansen, J H Marco; Raaben, Matthijs; Toebes, Mireille; Franke, Katka; Brandsma, Arianne M; Matlung, Hanke L; Fauster, Astrid; Gomez-Eerland, Raquel; Bakker, Noor A M; van der Schot, Simone; Marijt, Koen A; Verdoes, Martijn; Haanen, John B A G; van den Berg, Joost H; Neefjes, Jacques; van den Berg, Timo K; Brummelkamp, Thijn R; Leusen, Jeanette H W; Scheeren, Ferenc A; Schumacher, Ton N (Nature Research, 2019-04)

Cancer cells can evade immune surveillance through the expression of inhibitory ligands that bind their cognate receptors on immune effector cells. Expression of programmed death ligand 1 in tumor microenvironments is a ...
Potent Fc Receptor Signaling by IgA Leads to Superior Killing of Cancer Cells by Neutrophils Compared to IgG

Brandsma, Arianne M; Bondza, Sina; Evers, Mitchell; Koutstaal, Rosanne; Nederend, Maaike; Jansen, J H Marco; Rösner, Thies; Valerius, Thomas; Leusen, Jeanette H W; Ten Broeke, Toine (Frontiers Media S. A., 2019-01-01)

Antibody therapy of cancer is increasingly used in the clinic and has improved patient's life expectancy. Except for immune checkpoint inhibition, the mode of action of many antibodies is to recognize overexpressed or ...
Unique case of a rare mesenchymal tumor harboring a somatic c.119delC VHL mutation

Robbrecht, Debbie G.; Atrafi, Florence; Riet, Job van; Eskens, Ferry A.L.M.; van Diest, Paul J.; Cuppen, Edwin P.J.G.; van Leenders, Geert J.L.H.; van de Werken, Harmen J.G.; Lolkema, Martijn P. (Lippincott Williams & Wilkins, 2019-01-01)
Current Concepts in Severe Acute and Necrotizing Pancreatitis: An Evidence-Based Approach

Trikudanathan, Guru; Wolbrink, Daniel R.J.; van Santvoort, Hjalmar C.; Mallery, Shawn; Freeman, Martin; Besselink, Marc G. (W.B. Saunders, 2019-05-01)

The incidence of acute pancreatitis continues to rise, inducing substantial medical and social burden, with annual costs exceeding $2 billion in the United States alone. Although most patients develop mild pancreatitis, ...
Feasibility of transcervical robotic-assisted esophagectomy (TC-RAMIE) in a cadaver study-A future outlook for an extrapleural approach

Grimminger, Peter Philipp; van der Sluis, Pieter Christiaan; Stein, Hubert; Lang, Hauke; van Hillegersberg, Richard; Egberts, Jan Hendrik (Multidisciplinary Digital Publishing Institute (MDPI), 2019-09-01)

In recent years, the evolution of advanced robotic medical systems has increased rapidly. These technical developments have led to advanced robotic systems, such as the da Vinci Xi, which allows superior controlled complex ...
Increased matrix metalloproteinases expression in tuberous sclerosis complex: modulation by microRNA 146a and 147b in vitro

Broekaart, D. W.M.; van Scheppingen, J.; Anink, J. J.; Wierts, L.; van het Hof, B.; Jansen, F. E.; Spliet, W. G.; van Rijen, P. C.; Kamphuis, W. W.; de Vries, H. E.; Aronica, E.; van Vliet, E. A. (Wiley-Blackwell, 2020-02)

Aim: Matrix metalloproteinases (MMPs) and their endogenous tissue inhibitors (TIMPs) control proteolysis within the extracellular matrix (ECM) of the brain. Dysfunction of this enzymatic system due to brain inflammation ...
Precise detection of low-level somatic mutation in resected epilepsy brain tissue

Sim, Nam Suk; Ko, Ara; Kim, Woo Kyeong; Kim, Se Hoon; Kim, Ju Seong; Shim, Kyu Won; Aronica, Eleonora; Mijnsbergen, Caroline; Spliet, Wim G.M.; Koh, Hyun Yong; Kim, Heung Dong; Lee, Joon Soo; Kim, Dong Seok; Kang, Hoon Chul; Lee, Jeong Ho (Springer, 2019-12-01)

Low-level somatic mutations have been shown to be the major genetic etiology of intractable epilepsy. The extents thereof, however, have yet to be systematically and accurately explored in a large cohort of resected epilepsy ...
Immunometabolic signatures predict risk of progression to active tuberculosis and disease outcome

GC6-74 Consortium (Frontiers Media S. A., 2019-03-22)

There remains a pressing need for biomarkers that can predict who will progress to active tuberculosis (TB) after exposure to Mycobacterium tuberculosis (MTB) bacterium. By analyzing cohorts of household contacts of TB ...
Early Measles Vaccination During an Outbreak in the Netherlands: Short-Term and Long-Term Decreases in Antibody Responses Among Children Vaccinated Before 12 Months of Age

Brinkman, Iris D.; de Wit, Jelle; Smits, Gaby P.; Ten Hulscher, Hinke I.; Jongerius, Maria C.; Abreu, Taymara C.; van der Klis, Fiona R.M.; Hahné, Susan J.M.; Koopmans, Marion P.G.; Rots, Nynke Y.; van Baarle, Debbie; van Binnendijk, Robert S. (Oxford University Press, 2019-07-19)

BACKGROUND: The majority of infants will not be protected by maternal antibodies until their first measles vaccination, between 12 and 15 months of age. This provides incentive to reduce the age at measles vaccination, but ...
Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life

Reyman, Marta; van Houten, Marlies A.; van Baarle, Debbie; Bosch, Astrid A.T.M.; Man, Wing Ho; Chu, Mei Ling J.N.; Arp, Kayleigh; Watson, Rebecca L.; Sanders, Elisabeth A.M.; Fuentes, Susana; Bogaert, Debby (Nature Publishing Group, 2019-11-01)

The early-life microbiome appears to be affected by mode of delivery, but this effect may depend on intrapartum antibiotic exposure. Here, we assess the effect of delivery mode on gut microbiota, independent of intrapartum ...
Gene expression profiles classifying clinical stages of tuberculosis and monitoring treatment responses in Ethiopian HIV-negative and HIV-positive cohorts

Gebremicael, Gebremedhin; Kassa, Desta; Alemayehu, Yodit; Gebreegziaxier, Atsbeha; Kassahun, Yonas; van Baarle, Debbie; Ottenhoff, Tom H.M.; Cliff, Jacqueline M.; Haks, Mariëlle C. (Public Library of Science, 2019-01-01)

Background Validation of previously identified candidate biomarkers and identification of additional candidate gene expression profiles to facilitate diagnosis of tuberculosis (TB) disease and monitoring treatment responses ...
The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas

Bongaarts, Anika; van Scheppingen, Jackelien; Korotkov, Anatoly; Mijnsbergen, Caroline; Anink, Jasper J.; Jansen, Floor E.; Spliet, Wim G.M.; den Dunnen, Wilfred F.A.; Gruber, Victoria E.; Scholl, Theresa; Samueli, Sharon; Hainfellner, Johannes A.; Feucht, Martha; Kotulska, Katarzyna; Jozwiak, Sergiusz; Grajkowska, Wieslawa; Buccoliero, Anna Maria; Caporalini, Chiara; Giordano, Flavio; Genitori, Lorenzo; Coras, Roland; Blümcke, Ingmar; Krsek, Pavel; Zamecnik, Josef; Meijer, Lisethe; Scicluna, Brendon P.; Schouten-van Meeteren, Antoinette Y.N.; Mühlebner, Angelika; Mills, James D.; Aronica, Eleonora (Oxford University Press, 2020-01-01)

Tuberous sclerosis complex (TSC) is an autosomal dominantly inherited neurocutaneous disorder caused by inactivating mutations in TSC1 or TSC2, key regulators of the mechanistic target of rapamycin complex 1 (mTORC1) ...

Now showing items 19821-19840 of 40729