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Preemptive Stenting of the Vulnerable Plaque: Fixing a Dogma?

Pasterkamp, Gerard; van der Harst, Pim; den Ruijter, Hester M (Elsevier, 2020-11-17)
Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells

Aherrahrou, Rédouane; Guo, Liang; Nagraj, Vijay Peter; Aguhob, Aaron Andrew; Hinkle, Jameson; Chen, Lisa; Soh, Joon Yuhl; Lue, Dillon; Alencar, Gabriel F; Boltjes, Arjan; van der Laan, Sander W; Farber, Emily; Fuller, Daniela; Anane-Wae, Rita; Akingbesote, Ngozi D; Manichaikul, Ani W; Ma, Lijiang; Kaikkonen, Minna U; Björkegren, Johan Lm; Onengut-Gumuscu, Suna; Pasterkamp, Gerard; Miller, Clint L; Owens, Gary K; Finn, Aloke V; Navab, Mohamad; Fogelman, Alan M; Berliner, Judith A; Civelek, Mete (Lippincott Williams & Wilkins, 2020-12-04)

RATIONALE: Coronary artery disease (CAD) is a major cause of morbidity and mortality worldwide. Recent genome-wide association studies revealed 163 loci associated with CAD. However, the precise molecular mechanisms by ...
Refraining from resection in patients with potentially curable gastric carcinoma

Gertsen, Emma C.; Brenkman, Hylke J.F.; Brosens, L. A.A.; Luijten, Josianne C.H.B.M.; Mohammad, Nadia Haj; Verhoeven, Rob H.A.; van Hillegersberg, Richard; Ruurda, Jelle P. (W.B. Saunders Ltd, 2021-05)

Background: Surgical resection is the cornerstone of curative treatment for gastric cancer. The aim of this study was to evaluate reasons for and patient- and tumor characteristics that are associated with refraining from ...
No influence of sarcopenia on survival of ovarian cancer patients in a prospective validation study

Ubachs, Jorne; Koole, Simone N.; Lahaye, Max; Fabris, Cristina; Bruijs, Leigh; Schagen van Leeuwen, Jules; Schreuder, Henk W.R.; Hermans, R. H.; de Hingh, I. H.; van der Velden, J.; Arts, H. J.; van Ham, M.; van Dam, P.; Vuylsteke, P.; Bastings, Jacco; Kruitwagen, Roy F.P.M.; Lambrechts, Sandrina; Olde Damink, Steven W.M.; Rensen, Sander S.; Van Gorp, Toon; Sonke, Gabe S.; van Driel, Willemien J. (Academic Press Inc., 2020-12)

Objective: Decrease in skeletal muscle index (SMI) during neoadjuvant chemotherapy (NACT) has been associated with worse outcome in patients with advanced ovarian cancer. To validate these findings, we tested if a decrease ...
Bone texture analysis for prediction of incident radiographic hip osteoarthritis using machine learning: data from the Cohort Hip and Cohort Knee (CHECK) study

Hirvasniemi, J.; Gielis, W. P.; Arbabi, S.; Agricola, R.; van Spil, W. E.; Arbabi, V.; Weinans, H. (W.B. Saunders Ltd, 2019-06)

Objective: To assess the ability of radiography-based bone texture variables in proximal femur and acetabulum to predict incident radiographic hip osteoarthritis (rHOA) over a 10 years period. Design: Pelvic radiographs ...
Changes in the Position of the Junctional Vertebrae after Posterior Spinal Fusion in Adolescent Idiopathic Scoliosis: Implication in Risk Assessment of Proximal Junctional Kyphosis Development

Homans, Jelle F.; Kruyt, Moyo C.; Schlösser, Tom P.C.; Colo, Dino; Rogers, Kenneth; Shah, Suken A.; Flynn, John M.; Castelein, René M.; Pasha, Saba (Lippincott Williams & Wilkins, 2020-02-01)

BACKGROUND: The development of proximal junctional kyphosis (PJK) after posterior spinal fusion in adolescent idiopathic scoliosis is a major problem. Changes in the global sagittal parameters as they relate to PJK have ...
Can an mhealth clinical decision-making support system improve adherence to neonatal healthcare protocols in a low-resource setting?

Amoakoh, Hannah Brown; Klipstein-Grobusch, Kerstin; Agyepong, Irene Akua; Amoakoh-Coleman, Mary; Kayode, Gbenga A; Reitsma, J B; Grobbee, Diederick E; Ansah, Evelyn K (BioMed Central, 2020-12-27)

BACKGROUND: This study assessed health workers' adherence to neonatal health protocols before and during the implementation of a mobile health (mHealth) clinical decision-making support system (mCDMSS) that sought to bridge ...
Cytomegalovirus reactivations in the critically ill

Ong, D. S. Y.; Cremer, O. L. (Netherlands Society of Intensive Care, 2020-09)

Cytomegalovirus (CMV) reactivation is a well-recognised complication of solid organ and stem cell transplantation, causing both direct cytopathology in various organs and indirect immunomodulating effects. However, ...
Mitochondrial Fatty Acid Oxidation Disorders: Laboratory Diagnosis, Pathogenesis, and the Complicated Route to Treatment

Wanders, Ronald J A; Visser, Gepke; Ferdinandusse, Sacha; Vaz, Frédéric M; Houtkooper, Riekelt H (Korean Society of Lipid and Atherosclerosis, 2020-09)

Mitochondrial fatty acid (FA) oxidation deficiencies represent a genetically heterogeneous group of diseases in humans caused by defects in mitochondrial FA beta-oxidation (mFAO). A general characteristic of all mFAO ...
Conventional and Unconventional Therapeutic Strategies for Sialidosis Type I

Mosca, Rosario; van de Vlekkert, Diantha; Campos, Yvan; Fremuth, Leigh E; Cadaoas, Jaclyn; Koppaka, Vish; Kakkis, Emil; Tifft, Cynthia; Toro, Camilo; Allievi, Simona; Gellera, Cinzia; Canafoglia, Laura; Visser, Gepke; Annunziata, Ida; d'Azzo, Alessandra (Multidisciplinary Digital Publishing Institute (MDPI), 2020-03-04)

Congenital deficiency of the lysosomal sialidase neuraminidase 1 (NEU1) causes the lysosomal storage disease, sialidosis, characterized by impaired processing/degradation of sialo-glycoproteins and sialo-oligosaccharides, ...
Can sodium MRI be used as a method for mapping of cartilage stiffness?

Brinkhof, Sander; Froeling, Martijn; Janssen, Rob P A; Ito, Keita; Klomp, Dennis W J (Springer-Verlag, 2021-06)

OBJECTIVE: Sodium concentration is responsible for (at least part of) the stiffness of articular cartilage due to the osmotic pressure it generates. Therefore, we hypothesized that we could use sodium MRI to approximate ...
Evaluation of interrater reliability of different muscle segmentation techniques in diffusion tensor imaging

Forsting, Johannes; Rehmann, Robert; Rohm, Marlena; Froeling, Martijn; Schlaffke, Lara (John Wiley & Sons Inc., 2021-02)

Introduction: Muscle diffusion tensor imaging (mDTI) is a quantitative MRI technique that can provide information about muscular microstructure and integrity. Ultrasound and DTI studies have shown intramuscular differences, ...
Plasminogen glycoforms alteration and activation susceptibility associated with the missense variant p.Lys330Glu in HAE-PLG patients

Parsopoulou, Faidra; Charignon, Delphine; Tengo, Maud; Psarros, Fotis; Maas, Coen; Gonzalez-Quevedo, Teresa; Drouet, Christian; Germenis, Anastasios E; Ghannam, Arije (Wiley-Blackwell, 2020-08-01)
Detecting oral kallikrein-targeting therapy through triggered contact activation: A phase I study

Hofman, Zonne L M; Clark, Chantal C; Hack, C Erik; de Maat, Steven; Maas, Coen (Mosby Inc., 2020-12)
Patterns of C1-Inhibitor/Plasma Serine Protease Complexes in Healthy Humans and in Hereditary Angioedema Patients

Kajdácsi, Erika; Jandrasics, Zsófia; Veszeli, Nóra; Makó, Veronika; Koncz, Anna; Gulyás, Dominik; Köhalmi, Kinga Viktória; Temesszentandrási, György; Cervenak, László; Gál, Péter; Dobó, József; de Maat, Steven; Maas, Coen; Farkas, Henriette; Varga, Lilian (Frontiers Media S. A., 2020-05-05)

C1-inhibitor (C1-INH) is an important regulator of the complement, coagulation, fibrinolytic and contact systems. The quantity of protease/C1-INH complexes in the blood is proportional to the level of the in vivo activation ...
Outcomes Associated With Use of a Kinin B2 Receptor Antagonist Among Patients With COVID-19

van de Veerdonk, Frank L; Kouijzer, Ilse J E; de Nooijer, Aline H; van der Hoeven, Hans G; Maas, Coen; Netea, Mihai G; Brüggemann, Roger J M (American Medical Association, 2020-08-13)
Impaired Breakdown of Bradykinin and Its Metabolites as a Possible Cause for Pulmonary Edema in COVID-19 Infection

de Maat, Steven; de Mast, Quirijn; Danser, A H Jan; van de Veerdonk, Frank L; Maas, Coen (Thieme Medical Publishers, 2020-10-01)
Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate

Mailer, Reiner K; Allende, Mikel; Heestermans, Marco; Schweizer, Michaela; Deppermann, Carsten; Frye, Maike; Pula, Giordano; Odeberg, Jacob; Gelderblom, Mathias P; Rose-John, Stefan; Sickmann, Albert; Blankenberg, Stefan; Huber, Tobias B; Kubisch, Christian; Maas, Coen; Gambaryan, Stepan; Firsov, Dimitri; Stavrou, Evi X; Butler, Lynn; Renné, Thomas (Elsevier, 2021-03-11)

Polyphosphate is a procoagulant inorganic polymer of linear-linked orthophosphate residues. Multiple investigations have established the importance of platelet polyphosphate in blood coagulation; however, the mechanistic ...
Effectiviteit van influenzavaccinatie bij kinderen: Tijd voor een ander beleid?

Wildenbeest, Joanne G.; Verheij, Theo J.M. (Bohn Stafleu van Loghum, 2020-10)

A recent study found no protective effect of influenza vaccination on the frequency of respiratory tract infections in children with pre-existing medical conditions in the Netherlands, based on a retrospective primary care ...
Fractionation of Adipose Tissue Procedure with a Disposable One-Hole Fractionator

Van Dongen, Joris A.; Gostelie, Olivier F.E.; Vonk, Lucienne A.; De Bruijn, Julia J.; Van Der Lei, Berend; Harmsen, Martin C.; Stevens, Hieronymus P. (Oxford University Press, 2020-03-23)

Background: Adipose tissue has been widely used in regenerative surgery for its therapeutic potential. This potential is often ascribed to the stromal vascular fraction (SVF), which can be mechanically isolated. Mechanical ...

Now showing items 18001-18020 of 40729