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Now showing items 17921-17940 of 40729

Simulation at the Frontier of the Zone of Proximal Development: A Test in Acute Care for Inexperienced Learners

Groot, Fedde; Jonker, Gersten; Rinia, Myra; Ten Cate, Olle; Hoff, Reinier G. (Wolters Kluwer, 2020-07)

Purpose Vygotsky's zone of proximal development (ZPD) refers to the space between what learners have mastered and what they should master in the next developmental stage. Physicians' tasks are ZPD activities for medical ...
Postoperative visits by dedicated anesthesiologists in patients with elevated troponin: a retrospective cohort study evaluating postoperative care utility and early detection of complications

Akkermans, Annemarie; Vernooij, Lisette M; van Klei, Wilton A; van Waes, Judith A (2020-07-16)

Background: An elevated cardiac troponin level after noncardiac surgery is associated with both morbidity and mortality. Guidelines suggest routine troponin monitoring in high-risk patients. We implemented a dedicated ...
Stability of neuropsychological test performance in older adults serving as normative controls for a study on postoperative cognitive dysfunction

Feinkohl, Insa; Borchers, Friedrich; Burkhardt, Sarah; Krampe, Henning; Kraft, Antje; Speidel, Saya; Kant, Ilse M.J.; Van Montfort, Simone J.T.; Aarts, Ellen; Kruppa, Jochen; Slooter, Arjen; Winterer, Georg; Pischon, Tobias; Spies, Claudia (BioMed Central, 2020-02-04)

Objective: Studies of postoperative cognitive dysfunction (POCD) rely on repeat neuropsychological testing. The stability of the applied instruments, which are affected by natural variability in performance and measurement ...
Preoperative brain MRI features and occurrence of postoperative delirium

Kant, Ilse M J; van Montfort, Simone J T; Mutsaerts, Henri J M M; Witkamp, Theo D; Buijsrogge, Marc; Spies, Claudia; Hendrikse, Jeroen; Slooter, Arjen J C; de Bresser, Jeroen (Elsevier, 2021-01)

OBJECTIVE: Delirium is a frequent complication after surgery with important negative outcomes for affected patients and society. However, it is still largely unknown why some patients have a predisposition for delirium and ...
Effectiveness of Epiduroscopy for Patients with Failed Back Surgery Syndrome: a Systematic Review and Meta-analysis

Geudeke, Matthijs W; Krediet, Annelot C; Bilecen, Suleyman; Huygen, Frank J P M; Rijsdijk, Mienke (Wiley-Blackwell, 2021-04)

Introduction: Low-back or leg pain in patients suffering from failed back surgery syndrome (FBSS) is often severe, having a major impact on functionality and quality of life. Despite conservative and surgical treatments, ...
The rhythm of risk: sexual behaviour, PrEP use and HIV risk perception between 1999 and 2018 among men who have sex with men in Amsterdam, The Netherlands

Basten, Maartje; den Daas, Chantal; Heijne, Janneke C M; Boyd, Anders; Davidovich, Udi; Rozhnova, Ganna; Kretzschmar, Mirjam; Matser, Amy (Springer New York, 2021-06)

HIV risk perception plays a crucial role in the uptake of preventive strategies. We investigated how risk perception and its determinants changed between 1999 and 2018 in an open, prospective cohort of 1323 HIV-negative ...
Cerebral Blood Flow in Patients with Severe Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation

Vlastra, Wieneke; van Nieuwkerk, Astrid C; Bronzwaer, Anne-Sophie G T; Versteeg, Adriaan; Bron, Esther E; Niessen, Wiro J; Mutsaerts, Henk J M M; van der Ster, Björn J P; Majoie, Charles B L M; Biessels, Geert J; Nederveen, Aart J; Daemen, Mat J A P; van Osch, Matthias J P; Baan, Jan; Piek, Jan J; Van Lieshout, Johannes J; Delewi, Ronak (Wiley-Blackwell, 2021-02)

BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a minimally invasive, life-saving treatment for patients with severe aortic valve stenosis that improves quality of life. We examined cardiac output and cerebral ...
Cerebral Perfusion and the Burden of Small Vessel Disease in Patients Referred to a Memory Clinic

Utrecht VCI Study Group (S. Karger AG, 2020-11)

BACKGROUND: Cerebral small vessel disease (SVD) lesions on MRI are common in patients with cognitive impairment. It has been suggested that cerebral hypoperfusion is involved in the etiology of these lesions. OBJECTIVE: ...
Evaluation of a system for sorbent-assisted peritoneal dialysis in a uremic pig model

van Gelder, Maaike K; de Vries, Joost C; Simonis, Frank; Monninkhof, Anneke S; Hazenbrink, Diënty H M; Ligabue, Giulia; Giovanella, Silvia; Joles, Jaap A; Verhaar, Marianne C; Bajo Rubio, Maria A; Selgas, Rafael; Cappelli, Gianni; Gerritsen, Karin G F (John Wiley & Sons Inc., 2020-12)

A system for sorbent-assisted peritoneal dialysis (SAPD) has been developed that continuously recirculates dialysate via a tidal mode using a single-lumen peritoneal catheter with the regeneration of spent dialysate by ...
Cerebral Amyloid Angiopathy: Still a Syndromal Diagnosis

Biessels, Geert Jan (Lippincott Williams & Wilkins, 2020-12)
Background incidence rates of adverse pregnancy outcomes in the Netherlands: Data of 2006-2018

Immink, Maarten M; Koole, Sanne; Bekker, Mireille N; Groenendaal, Floris; Kemmeren, Jeanet M; de Melker, Hester E; van der Maas, Nicoline A T (Elsevier Ireland Ltd, 2021-01)

OBJECTIVE: Maternal vaccination is an effective and safe intervention to protect newborns against infectious diseases shortly after birth. We assessed background rates of adverse pregnancy outcomes before the implementation ...
Targeting the RhoGEF βPIX/COOL-1 in Glioblastoma: Proof of Concept Studies

Connor, Kate; Murray, David W; Jarzabek, Monika A; Tran, Nhan L; White, Kieron; Dicker, Patrick; Sweeney, Kieron J; O'Halloran, Philip J; MacCarthy, Brian; Shiels, Liam P; Lodi, Francesca; Lambrechts, Diether; Sarkaria, Jann N; Schiffelers, Raymond M; Symons, Marc; Byrne, Annette T (Multidisciplinary Digital Publishing Institute (MDPI), 2020-12)

Glioblastoma (GBM), a highly invasive and vascular malignancy is shown to rapidly develop resistance and evolve to a more invasive phenotype following bevacizumab (Bev) therapy. Rho Guanine Nucleotide Exchange Factor ...
Treatment strategies and clinical outcomes in consecutive patients with locally advanced pancreatic cancer: A multicenter prospective cohort

Dutch Pancreatic Cancer Group (W.B. Saunders Ltd, 2021-03)

INTRODUCTION: Since current studies on locally advanced pancreatic cancer (LAPC) mainly report from single, high-volume centers, it is unclear if outcomes can be translated to daily clinical practice. This study provides ...
Scalar Translocation Comparison Between Lateral Wall and Perimodiolar Cochlear Implant Arrays - A Meta-Analysis

Jwair, Saad; Prins, Adrianus; Wegner, Inge; Stokroos, Robert J; Versnel, Huib; Thomeer, Hans G X M (John Wiley & Sons Inc., 2021-06)

OBJECTIVES/HYPOTHESIS: Two types of electrode arrays for cochlear implants (CIs) are distinguished: lateral wall and perimodiolar. Scalar translocation of the array can lead to intracochlear trauma by penetrating from the ...
BDNF-mediated preservation of spiral ganglion cell peripheral processes and axons in comparison to that of their cell bodies

Vink, Henk A; Versnel, Huib; Kroon, Steven; Klis, Sjaak F L; Ramekers, Dyan (Elsevier, 2021-02)

Treatment with neurotrophins prevents degeneration of spiral ganglion cells (SGCs) after severe hair cell loss. In a previous study we demonstrated a long-lasting effect with brain-derived neurotrophic factor (BDNF) after ...
Extended Resections for Advanced Gallbladder Cancer: Results from a Nationwide Cohort Study

Kuipers, H; de Savornin Lohman, E A J; van Dooren, M; Braat, A E; Daams, F; van Dam, R; Erdmann, J I; Hagendoorn, J; Hoogwater, F J H; Groot Koerkamp, B; van Gulik, T M; de Reuver, P R; de Boer, M T (Springer New York, 2021-02)

BACKGROUND: Extended resections (i.e., major hepatectomy and/or pancreatoduodenectomy) are rarely performed for gallbladder cancer (GBC) because outcomes remain inconclusive. Data regarding extended resections from Western ...
Innovative Tissue-Engineered Strategies for Osteochondral Defect Repair and Regeneration: Current Progress and Challenges

Zhou, Liangbin; Gjvm, Van Osch; Malda, Jos; Stoddart, Martin J.; Lai, Yuxiao; Richards, R. Geoff; Ki-wai Ho, Kevin; Qin, Ling (John Wiley & Sons Inc., 2020-12-02)

Clinical treatments for the repair of osteochondral defects (OCD) are merely palliative, not completely curative, and thus enormously unfulfilled challenges. With the in-depth studies of biology, medicine, materials, and ...
Hospital variation in combined liver resection and thermal ablation for colorectal liver metastases and impact on short-term postoperative outcomes: a nationwide population-based study

Dutch Hepato Biliary Audit Group (John Wiley & Sons Inc., 2021-06)

BACKGROUND: Combining resection and thermal ablation can improve short-term postoperative outcomes in patients with colorectal liver metastases (CRLM). This study assessed nationwide hospital variation and short-term ...
Rapid Photocrosslinking of Silk Hydrogels with High Cell Density and Enhanced Shape Fidelity: Rapid Photocrosslinking of Silk Hydrogels with High Cell Density and Enhanced Shape Fidelity (Adv. Healthcare Mater, (2020), 9, (1901667), 10.1002/adhm.201901667)

Cui, Xiaolin; Soliman, Bram G.; Alcala-Orozco, Cesar R.; Li, Jun; Vis, Michelle A.M.; Santos, Miguel; Wise, Steven G.; Levato, Riccardo; Malda, Jos; Woodfield, Tim B.F.; Rnjak-Kovacina, Jelena; Lim, Khoon S. (John Wiley & Sons Inc., 2020-11-18)

Adv. Healthcare Mater. 2020, 9, 1901667 DOI: 10.1002/adhm.201901667 In the original version of this article, there was a mistake in Figure 3 due to errors during the compilation of the images. The correct figure is shown ...
Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

HUNT All-In Stroke; China Kadoorie Biobank Collaborative Group; BioBank Japan Project Consortium; The ICAN Study Group; CADISP Group; Genetics and Observational Subarachnoid Haemorrhage (GOSH) Study investigators; International Stroke Genetics Consortium (ISGC) (Nature Research, 2020-12)

Rupture of an intracranial aneurysm leads to subarachnoid hemorrhage, a severe type of stroke. To discover new risk loci and the genetic architecture of intracranial aneurysms, we performed a cross-ancestry, genome-wide ...

Now showing items 17921-17940 of 40729