Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

Now showing items 17821-17840 of 40729

Prediction models for COVID-19 clinical decision making

Leeuwenberg, Artuur M; Schuit, Ewoud (Elsevier, 2020-10)
Text-mining in electronic healthcare records can be used as efficient tool for screening and data-collection in cardiovascular trials: a multicenter validation study

van Dijk, Wouter B; Fiolet, Aernoud T L; Schuit, Ewoud; Sammani, Arjan; Groenhof, T Katrien J; van der Graaf, Rieke; de Vries, Martine C; Alings, Marco; Schaap, Jeroen; Asselbergs, Folkert W; Grobbee, Diederick E; Groenwold, Rolf H H; Mosterd, Arend (Elsevier, 2021-04)

Objective: This study aimed to validate trial patient eligibility screening and baseline data collection using text-mining in electronic healthcare records (EHRs), comparing the results to those of an international trial. ...
Longitudinal analysis of T-cell receptor repertoires reveals persistence of antigen-driven CD4+ and CD8+ T-cell clusters in systemic sclerosis

Servaas, N H; Zaaraoui-Boutahar, F; Wichers, C G K; Ottria, A; Chouri, E; Affandi, A J; Silva-Cardoso, S; van der Kroef, M; Carvalheiro, T; van Wijk, F; Radstake, T R D J; Andeweg, A C; Pandit, A (Academic Press Inc., 2021-02)

The T-cell receptor (TCR) is a highly polymorphic surface receptor that allows T-cells to recognize antigenic peptides presented on the major histocompatibility complex (MHC). Changes in the TCR repertoire have been observed ...
Cardiovascular risk prediction tools made relevant for GPs and patients

De Vries, Tamar I.; Visseren, Frank L.J. (BMJ Publishing Group, 2021-02-01)
Utilization of systemic treatment for metastatic bladder cancer in everyday practice: Results of a nation-wide population-based cohort study

Richters, Anke; Mehra, Niven; Meijer, Richard P; Boormans, Joost L; van der Heijden, Antoine G; Smilde, Tineke J; van der Heijden, Michiel S; Kiemeney, Lambertus A; Aben, Katja K (Elsevier, 2020)

BACKGROUND: With the introduction of new therapeutic options, the landscape of metastatic bladder cancer (mBC) management is shifting. We describe current clinical practice and outcomes of mBC patients as a benchmark for ...
Novel chimerized IgA CD20 antibodies: Improving neutrophil activation against CD20-positive malignancies

Evers, Mitchell; ten Broeke, Toine; Jansen, Marco; Nederend, Maaike; Hamdan, Firas; Reiding, Karli R; Meyer, Saskia; Moerer, Petra; Brinkman, Iris; Thies, Rösner; Lebbink, Robert Jan; Valerius, Thomas; Leusen, Jeanette (Landes Bioscience, 2020-08-04)

Current combination therapies elicit high response rates in B cell malignancies, often using CD20 antibodies as the backbone of therapy. However, many patients eventually relapse or develop progressive disease. Therefore, ...
TINF2 is a haploinsufficient tumor suppressor that limits telomere length

Schmutz, Isabelle; Mensenkamp, Arjen R; Takai, Kaori K; Haadsma, Maaike; Spruijt, Liesbeth; de Voer, Richarda M; Choo, Seunga Sara; Lorbeer, Franziska K; van Grinsven, Emma J; Hockemeyer, Dirk; Jongmans, Marjolijn Cj; de Lange, Titia (eLife Sciences Publications, 2020-12-01)

Telomere shortening is a presumed tumor suppressor pathway that imposes a proliferative barrier (the Hayflick limit) during tumorigenesis. This model predicts that excessively long somatic telomeres predispose to cancer. ...
Genetics-first approach improves diagnostics of ESKD patients <50 years old

Snoek, Rozemarijn; van Jaarsveld, Richard H; Nguyen, Tri Q; Peters, Edith D J; Elferink, Martin G; Ernst, Robert F; Rookmaaker, Maarten B; Lilien, Marc R; Spierings, Eric; Goldschmeding, Roel; Knoers, Nine V A M; van der Zwaag, Bert; van Zuilen, Arjan D; van Eerde, Albertien M (Oxford University Press, 2022-02)

Background: Often only chronic kidney disease (CKD) patients with high likelihood of genetic disease are offered genetic testing. Early genetic testing could obviate the need for kidney biopsies, allowing for adequate ...
Re: Tamsulosin as a Medical Expulsive Therapy for Ureteral Stones: A Systematic Review and Meta-Analysis of Randomized Controlled Trials: Tamsulosin as a Medical Expulsive Therapy for Ureteral Stones: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsY. Cui, J. Chen, F. Zeng, P. Liu, J. Hu, H. Li, C. Li, X. Cheng, M. Chen, Y. Li, Y. Li, Z. Yang, Z. Chen, H. Chand, H. Chen and X. Zu J Urol 2019; 201: 950-955

Campschroer, Thijs; Zhu, Xiaoye; Vernooij, Robin; Lock, Tycho (Elsevier, 2020-06-01)
Sudden cardiac death in dialysis patients: different causes and management strategies

Genovesi, Simonetta; Boriani, Giuseppe; Covic, Adrian; Vernooij, Robin W M; Combe, Christian; Burlacu, Alexandru; Davenport, Andrew; Kanbay, Mehmet; Kirmizis, Dimitrios; Schneditz, Daniel; van der Sande, Frank; Basile, Carlo (Oxford University Press, 2021-03)

Sudden cardiac death (SCD) represents a major cause of death in end-stage kidney disease (ESKD). The precise estimate of its incidence is difficult to establish because studies on the incidence of SCD in ESKD are often ...
Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively healthy people in late life

Gates, Nicola J; Rutjes, Anne Ws; Di Nisio, Marcello; Karim, Salman; Chong, Lee-Yee; March, Evrim; Martínez, Gabriel; Vernooij, Robin Wm (John Wiley & Sons Inc., 2020-02-27)

BACKGROUND: Increasing age is associated with a natural decline in cognitive function and is the greatest risk factor for dementia. Cognitive decline and dementia are significant threats to independence and quality of life ...
An International Survey on the Use of Thromboprophylaxis in Urological Surgery

Violette, Philippe D; Vernooij, Robin W M; Aoki, Yoshitaka; Agarwal, Arnav; Cartwright, Rufus; Arai, Yoichi; Tailly, Thomas; Novara, Giacomo; Baldeh, Tejan; Craigie, Samantha; Breau, Rodney H; Guyatt, Gordon H; Tikkinen, Kari A O (Elsevier, 2021-05)

Background: The use of perioperative thromboprophylaxis in urological surgery is common but not standardized. Objective: To characterize international practice variation in thromboprophylaxis use in urological surgery. ...
Drug treatments for covid-19: living systematic review and network meta-analysis

Siemieniuk, Reed Ac; Bartoszko, Jessica J; Ge, Long; Zeraatkar, Dena; Izcovich, Ariel; Kum, Elena; Pardo-Hernandez, Hector; Rochwerg, Bram; Lamontagne, Francois; Han, Mi Ah; Liu, Qin; Agarwal, Arnav; Agoritsas, Thomas; Chu, Derek K; Couban, Rachel; Darzi, Andrea; Devji, Tahira; Fang, Bo; Fang, Carmen; Flottorp, Signe Agnes; Foroutan, Farid; Heels-Ansdell, Diane; Honarmand, Kimia; Hou, Liangying; Hou, Xiaorong; Ibrahim, Quazi; Loeb, Mark; Marcucci, Maura; McLeod, Shelley L; Motaghi, Sharhzad; Murthy, Srinivas; Mustafa, Reem A; Neary, John D; Qasim, Anila; Rada, Gabriel; Riaz, Irbaz Bin; Sadeghirad, Behnam; Sekercioglu, Nigar; Sheng, Lulu; Sreekanta, Ashwini; Switzer, Charlotte; Tendal, Britta; Thabane, Lehana; Tomlinson, George; Turner, Tari; Vandvik, Per O; Vernooij, Robin Wm; Viteri-García, Andrés; Wang, Ying; Yao, Liang; Ye, Zhikang; Guyatt, Gordon H; Brignardello-Petersen, Romina (BMJ Publishing Group, 2020-07-30)

OBJECTIVE: To compare the effects of treatments for coronavirus disease 2019 (covid-19). DESIGN: Living systematic review and network meta-analysis. DATA SOURCES: US Centers for Disease Control and Prevention COVID-19 ...
Effects of oncological care pathways in primary and secondary care on patient, professional and health systems outcomes: a systematic review and meta-analysis

van Hoeve, Jolanda C; Vernooij, Robin W M; Fiander, Michelle; Nieboer, Peter; Siesling, Sabine; Rotter, Thomas (BioMed Central, 2020-12-01)

BACKGROUND: Pathways are frequently used to improve care for cancer patients. However, there is little evidence about the effects of pathways used in oncological care. Therefore, we performed a systematic review and ...
Phlebotonics for venous insufficiency

Martinez-Zapata, Maria José; Vernooij, Robin Wm; Simancas-Racines, Daniel; Uriona Tuma, Sonia Maria; Stein, Airton T; Moreno Carriles, Rosa Maria M; Vargas, Emilio; Bonfill Cosp, Xavier (John Wiley & Sons Inc., 2020-11-03)

BACKGROUND: Chronic venous insufficiency (CVI) is a condition in which veins are unable to transport blood unidirectionally towards the heart. CVI usually occurs in the lower limbs. It might result in considerable discomfort, ...
Alpha-blockers after shock wave lithotripsy for renal or ureteral stones in adults

Oestreich, Makinna C; Vernooij, Robin WM; Sathianathen, Niranjan J; Hwang, Eu Chang; Kuntz, Gretchen M; Koziarz, Alex; Scales, Charles D; Dahm, Philipp (John Wiley & Sons Inc., 2020-11-12)

BACKGROUND: Shock wave lithotripsy (SWL) is a widely used method to treat renal and ureteral stone. It fragments stones into smaller pieces that are then able to pass spontaneously down the ureter and into the bladder. ...
Art in Endoscopy: Bleeding art

Monkelbaan, Jan F.; Pullens, Hendrikus J.M. (Georg Thieme Verlag, 2020-12-01)
CXCL4 Links Inflammation and Fibrosis by Reprogramming Monocyte-Derived Dendritic Cellsin vitro

Silva-Cardoso, Sandra C.; Tao, Weiyang; Angiolilli, Chiara; Lopes, Ana P.; Bekker, Cornelis P. J.; Devaprasad, Abhinandan; Giovannone, Barbara; van Laar, Jaap; Cossu, Marta; Marut, Wioleta; Hack, Erik; de Boer, Rob J.; Boes, Marianne; Radstake, Timothy R. D. J.; Pandit, Aridaman (Frontiers Media S. A., 2020-09-17)

Fibrosis is a condition shared by numerous inflammatory diseases. Our incomplete understanding of the molecular mechanisms underlying fibrosis has severely hampered effective drug development. CXCL4 is associated with the ...
Stereotactic radiotherapy combined with immunotherapy or targeted therapy for metastatic renal cell carcinoma

Kroeze, Stephanie G C; Fritz, Corinna; Schaule, Jana; Siva, Shankar; Kahl, Klaus H; Sundahl, Nora; Blanck, Oliver; Kaul, David; Adebahr, Sonja; Verhoeff, Joost J C; Skazikis, Georgios; Roeder, Falk; Geier, Michael; Eckert, Franziska; Guckenberger, Matthias (Wiley-Blackwell, 2021-06)

OBJECTIVES: To evaluate the safety and efficacy of stereotactic radiotherapy (SRT) in patients with metastatic renal cell carcinoma (mRCC) concurrently receiving targeted therapy (TT) or immunotherapy. PATIENTS AND METHODS: ...
Dose-dependent volume loss in subcortical deep grey matter structures after cranial radiotherapy

Nagtegaal, Steven H J; David, Szabolcs; Philippens, Marielle E P; Snijders, Tom J; Leemans, Alexander; Verhoeff, Joost J C (Elsevier Ireland Ltd, 2021-01)

Background and purpose: The relation between radiotherapy (RT) dose to the brain and morphological changes in healthy tissue has seen recent increased interest. There already is evidence for changes in the cerebral cortex ...

Now showing items 17821-17840 of 40729