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Now showing items 17661-17680 of 40729

Modeling Personalized Adjuvant TreaTment in EaRly stage coloN cancer (PATTERN)

Jongeneel, Gabrielle; Greuter, Marjolein J E; van Erning, Felice N; Koopman, Miriam; Medema, Jan P; Kandimalla, Raju; Goel, Ajay; Bujanda, Luis; Meijer, Gerrit A; Fijneman, Remond J A; van Oijen, Martijn G H; Ijzermans, Jan; Punt, Cornelis J A; Vink, Geraldine R; Coupé, Veerle M H (Springer-Verlag, 2020-09)

AIM: To develop a decision model for the population-level evaluation of strategies to improve the selection of stage II colon cancer (CC) patients who benefit from adjuvant chemotherapy. METHODS: A Markov cohort model with ...
Model-based evaluation of the cost effectiveness of 3 versus 6 months' adjuvant chemotherapy in high-risk stage II colon cancer patients

Jongeneel, Gabrielle; Greuter, Marjolein J E; van Erning, Felice N; Koopman, Miriam; Vink, Geraldine R; Punt, Cornelis J A; Coupé, Veerle M H (SAGE Publications Ltd, 2020-09)

Background: Our aim was to evaluate the cost effectiveness of 3 months' adjuvant chemotherapy versus 6 months in high-risk (T4 stage + microsatellite stable) stage II colon cancer (CC) patients. Methods: Using the validated ...
Endothelium-Derived Extracellular Vesicles Associate with Poor Prognosis in Metastatic Colorectal Cancer

Nanou, Afroditi; Mol, Linda; Coumans, Frank A W; Koopman, Miriam; Punt, Cornelis J A; Terstappen, Leon W M M (Multidisciplinary Digital Publishing Institute (MDPI), 2020-12-15)

Elevated, tumor-derived extracellular vesicle (tdEV) and circulating tumor cell (CTC) loads in metastatic cancer are associated with poor clinical outcome. Herein, we investigate whether endothelium-derived extracellular ...
Impact of Complications After Pancreatoduodenectomy on Mortality, Organ Failure, Hospital Stay, and Readmission: Analysis of a Nationwide Audit

Dutch Pancreatic Cancer Group (Lippincott Williams & Wilkins, 2022-01-01)

OBJECTIVE: To quantify the impact of individual complications on mortality, organ failure, hospital stay, and readmission after pancreatoduodenectomy. SUMMARY OF BACKGROUND DATA: An initial complication may provoke a ...
De-escalation of axillary surgery in breast cancer patients treated in the neoadjuvant setting: a Dutch population-based study

Simons, J M; Koppert, L B; Luiten, E J T; van der Pol, C C; Samiei, S; de Wilt, J H W; Siesling, S; Smidt, M L (Springer New York, 2020-04)

Purpose: An overall trend is observed towards de-escalation of axillary surgery in patients with breast cancer. The objective of this study was to evaluate this trend in patients treated with neoadjuvant systemic therapy ...
Patterns of axillary staging and management in clinically node positive breast cancer patients treated with neoadjuvant systemic therapy: Results of a survey amongst breast cancer specialists

Simons, J M; Maaskant-Braat, A J G; Luiten, E J T; Leidenius, M H K; van Nijnatten, T J A; Boelens, P G; Koppert, L B; van der Pol, C C; van de Velde, C J H; Audisio, R A; Smidt, M L (W.B. Saunders Ltd, 2020-01)

INTRODUCTION: Various options for axillary staging after neoadjuvant systemic therapy (NST) are available for breast cancer patients with a clinically positive axillary node (cN+). This survey assessed current practices ...
Reply to: Sentinel node biopsy after neoadjuvant chemotherapy for breast cancer in patients with pre-treatment node-positive: Recommendation to optimize the performance

Simons, J M; Maaskant-Braat, A J G; Luiten, E J T; Leidenius, M H; van Nijnatten, T J A; Boelens, P G; Koppert, L B; van der Pol, C C; van de Velde, C J H; Audisio, R A; Smidt, M L (W.B. Saunders Ltd, 2020-01)
Can serial cerebral MRIs predict the neuronopathic phenotype of MPS II ?

Vollebregt, Audrey A M; Ebbink, Berendine J; Rizopoulos, Dimitris; Lequin, Maarten H; Aarsen, Femke K; Shapiro, Elsa G; van der Ploeg, Ans T; van den Hout, Johanna M P (Springer Netherlands, 2021-05)

Objective: To advance the prediction of the neurocognitive development in MPS II patients by jointly analyzing MRI and neurocognitive data in mucopolysaccharidosis (MPS) II patients. Methods: Cognitive ability scores (CAS) ...
Study protocol for a multicenter prospective cohort study on esophagogastric anastomoses and anastomotic leak (the Oesophago-Gastric Anastomosis Audit/OGAA)

Evans, R. P.T.; Singh, P.; Nepogodiev, D.; Bundred, J.; Kamarajah, S.; Jefferies, B.; Siaw-Acheampong, K.; Wanigasooriya, K.; McKay, S.; Mohamed, I.; Whitehouse, T.; Alderson, D.; Gossage, J.; Van Hillegersberg, R.; Vohra, R. S.; Griffiths, E. A. (Wiley-Blackwell, 2020-01-07)

Esophagectomy is a mainstay in curative treatment for esophageal cancer; however, the reported techniques and outcomes can vary greatly. Thirty-day mortality of patients with an intact anastomosis is 2-3% as compared to ...
Defining Major Surgery: A Delphi Consensus Among European Surgical Association (ESA) Members

the ESA Study Group (Springer New York, 2020-07-01)

Background: Major surgery is a term frequently used but poorly defined. The aim of the present study was to reach a consensus in the definition of major surgery within a panel of expert surgeons from the European Surgical ...
Monitoring eosinophils to guide therapy with Biologics in Asthma: does the compartment matter?

Koenderman, Leo; Hassani, Marwan; Mukherjee, Manali; Nair, Parameswaran (Wiley-Blackwell, 2021-04)

Eosinophils, since their initial description by Thomas Wharton Jones in 1846, and staining characteristics by Paul Ehrlich in 1879, have been associated with asthma1 . They are produced in the bone marrow, from pluripotential ...
Cranial Ultrasound Is an Important Tool in the Recognition of Life-Threatening Infratentorial Hemorrhage in Newborns

van Steenis, A; Fumagalli, M; Kruit, M C; Peeters-Scholte, C M P C D; de Vries, L S; Steggerda, S J (Georg Thieme Verlag, 2021-06)

Timely detection of severe infratentorial hemorrhage in neonates is crucial, especially in case of life-threatening brain stem compression and/or acute obstructive hydrocephalus, which need lifesaving neurosurgical ...
Long-term outcomes of the hip shelf arthroplasty in adolescents and adults with residual hip dysplasia: a systematic review

Willemsen, Koen; Doelman, Christiaan J; Sam, Ali S Y; Seevinck, Peter R; Sakkers, Ralph J B; Weinans, Harrie; van Der Wal, Bart C H (Informa Healthcare, 2020-07-03)

Background and purpose - The shelf arthroplasty was the regular treatment for residual hip dysplasia before it was substituted by the peri-acetabular osteotomy. Yet, evidence regarding the survival of shelf arthroplasty ...
Combined massive allograft and intramedullary vascularized fibula transfer: the Capanna technique for treatment of congenital pseudarthrosis of the tibia

Van Den Heuvel, Stefanie C M; Winters, Hay A H; Ultee, Klaas H; Zijlstra-Koenrades, Nienke; Sakkers, Ralph J B (Informa Healthcare, 2020-10)

Background and purpose - Congenital pseudarthrosis of the tibia (CPT) is caused by local periosteal disease that can lead to bowing, fracturing, and pseudarthrosis. Current most successful treatment methods are segmental ...
Abduction treatment in stable hip dysplasia does not alter the acetabular growth: results of a randomized clinical trial

Pollet, V; Castelein, R M; van de Sande, M; Witbreuk, M; Mostert, A K; Besselaar, A; van Bergen, C; Beek, E; Uiterwaal, C S P M; Sakkers, R J B (Nature Publishing Group, 2020-06-15)

Background The effect of bracing over natural history of stable dysplastic hips is not well known. This multicenter randomized trial aimed at objectifying the effect of abduction treatment versus active surveillance in ...
Can dual mobility cups prevent dislocation without increasing revision rates in primary total hip arthroplasty?: A systematic review

Jonker, Ragna C; van Beers, Loes W A H; van der Wal, Bart C H; Vogely, H Charles; Parratte, Sebastien; Castelein, René M; Poolman, Rudolf W (Elsevier Masson, 2020-05)

BACKGROUND: Dislocation is one of the leading causes for early revision surgery after total hip arthroplasty (THA). To address this problem, the dual mobility (DM) cup was developed in the 1970s by the French. Despite the ...
Sonication Leads to Clinically Relevant Changes in Treatment of Periprosthetic Hip or Knee Joint Infection

Hoekstra, Marrit; Veltman, Ewout S; Nurmohamed, Ruben F R H A; van Dijk, Bruce; Rentenaar, Rob J; Vogely, H Charles; van der Wal, Bart C H (Copernicus GmbH, 2020-04-24)

Background: Diagnosis of periprosthetic joint infection (PJI) can be troublesome. Sonication can be a helpful tool in culturing bacteria that are difficult to detect with standard tissue cultures. Aim of this study is to ...
The Value of SPECT/CT for Knee Osteoarthritis: A Systematic Review

Zarringam, D; Saris, D B F; Bekkers, J E J (SAGE Publications Inc., 2021-10)

BACKGROUND: Single photon emission computed tomography (SPECT/CT) is a diagnostic option for knee osteoarthritis patients without osteoarthritic features on X-ray; however, the added value of SPECT/CT remains debatable in ...
Fresh Osteochondral Allograft Transplantation in the Knee: A Viability and Histologic Analysis for Optimizing Graft Viability and Expanding Existing Standard Processed Graft Resources Using a Living Donor Cartilage Program

Hevesi, Mario; Denbeigh, Janet M; Paggi, Carlo A; Galeano-Garces, Catalina; Bagheri, Leila; Larson, A Noelle; Stuart, Michael J; Saris, Daniel B F; van Wijnen, Andre J; Krych, Aaron J (SAGE Publications Inc., 2021-12)

Objective: This study aims to (1) determine and validate living cartilage allograft transplantation as a novel source for viable osteochondral allograft (OCA) tissues and (2) perform histologic and viability comparisons ...
Modernizing Storage Conditions for Fresh Osteochondral Allografts by Optimizing Viability at Physiologic Temperatures and Conditions

Denbeigh, Janet M; Hevesi, Mario; Paggi, Carlo A; Resch, Zachary T; Bagheri, Leila; Mara, Kristin; Arani, Arvin; Zhang, Chenghao; Larson, A Noelle; Saris, Daniel B F; Krych, Aaron J; van Wijnen, Andre J (SAGE Publications Inc., 2021-12)

Objective. Osteochondral allograft (OCA) transplantation has demonstrated good long-term outcomes in treatment of cartilage defects. Viability, a key factor in clinical success, decreases with peri-implantation storage at ...

Now showing items 17661-17680 of 40729