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UMC Repository: Recent submissions

  • Effects of exergaming on exercise capacity in patients with heart failure: results of an international multicentre randomized controlled trial 
    Jaarsma, Tiny; Klompstra, Leonie; Ben Gal, Tuvia; Ben Avraham, Binyamin; Boyne, Josiane; Bäck, Maria; Chialà, Oronzo; Dickstein, Kenneth; Evangelista, Lorraine; Hagenow, Andreas; Hoes, Arno W; Hägglund, Eva; Piepoli, Massimo F; Vellone, Ercole; Zuithoff, Nicolaas P A; Mårtensson, Jan; Strömberg, Anna (Oxford University Press, 2021-01)
    Aims Exergaming is a new tool to increase physical activity. This study aimed to determine the effects of access to a home-based exergame (Nintendo Wii) in patients with heart failure (HF) on exercise capacity, self-reported ...
  • Changes in primary and secondary hemostasis in patients with CLL treated with venetoclax and ibrutinib 
    Svanberg, Rebecka; Ostrowski, Sisse Rye; Nasserinejad, Kazem; Kersting, Sabina; Dobber, Johan A; Mattson, Mattias; Tran, Hoa T T; Levin, Mark-David; Mous, Rogier; Kater, Arnon P; Niemann, Carsten U (2020-12-05)
    Bleeding is a common adverse event following ibrutinib monotherapy. However, it remains unclear how hemostasis is affected by venetoclax in combination with ibrutinib. Here we investigated hemostasis in patients with chronic ...
  • A Systematic Review of Focal Ablative Therapy for Clinically Localised Prostate Cancer in Comparison with Standard Management Options: Limitations of the Available Evidence and Recommendations for Clinical Practice and Further Research 
    Bates, Anthony S; Ayers, Jennifer; Kostakopoulos, Nikolaos; Lumsden, Thomas; Schoots, Ivo G; Willemse, Peter-Paul M; Yuan, Yuhong; van den Bergh, Roderick C N; Grummet, Jeremy P; van der Poel, Henk G; Rouvière, Olivier; Moris, Lisa; Cumberbatch, Marcus G; Lardas, Michael; Liew, Matthew; Van den Broeck, Thomas; Gandaglia, Giorgio; Fossati, Nicola; Briers, Erik; De Santis, Maria; Fanti, Stefano; Gillessen, Silke; Oprea-Lager, Daniela E; Ploussard, Guillaume; Henry, Ann M; Tilki, Derya; van der Kwast, Theodorus H; Wiegel, Thomas; N'Dow, James; Mason, Malcolm D; Cornford, Philip; Mottet, Nicolas; Lam, Thomas B L (Elsevier, 2021-06)
    CONTEXT: The clinical effectiveness of focal therapy (FT) for localised prostate cancer (PCa) remains controversial. OBJECTIVE: To analyse the evidence base for primary FT for localised PCa via a systematic review (SR) to ...
  • The Number of Concomitant Drugs and the Safety of Direct Oral Anticoagulants in Routine Care Patients with Atrial Fibrillation 
    van den Dries, Carline J; van Doorn, Sander; Souverein, Patrick; Pajouheshnia, Romin; Moons, Karel G M; Hoes, Arno W; Geersing, Geert-Jan; van den Ham, Hendrika A (Thieme, 2020-12-23)
    Background  The benefit of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKAs) on major bleeding was less prominent among atrial fibrillation (AF) patients with polypharmacy in post-hoc randomized ...
  • Effects of 13-valent pneumococcal conjugate vaccination of adults on lower respiratory tract infections and antibiotic use in primary care: authors' response 
    van Werkhoven, Cornelis H; Bolkenbaas, Marieke; Huijts, Susanne M; Verheij, Theo J M; Bonten, Marc J M (Elsevier, 2021-06)
    In response to Theilacker et al. we explain that we consider the point estimate as well as the confidence bounds in our interpretation of the study results and do not treat confidence intervals as a dichotomous signal. We ...
  • Reply by Authors 
    Rosenberg, Steven; Bonten, Marc; Haazen, Wouter; Spiessens, Bart; Abbanat, Darren; Go, Oscar; Wagenlehner, Florian; Shore, Neal; Hagiwara, Yosuke; Ibarra de Palacios, Patricia; Geurtsen, Jeroen; Hermans, Peter; Poolman, Jan (Elsevier, 2021-03-01)
  • Coordinating Global Multi-Site Studies of Military-Relevant Traumatic Brain Injury: Opportunities, Challenges, and Harmonization Guidelines 
    Tate, David F; Dennis, Emily L; Adams, John T; Adamson, Maheen M; Belanger, Heather G; Bigler, Erin D; Bouchard, Heather C; Clark, Alexandra L; Delano-Wood, Lisa M; Disner, Seth G; Eapen, Blessen C; Franz, Carol E; Geuze, Elbert; Goodrich-Hunsaker, Naomi J; Han, Kihwan; Hayes, Jasmeet P; Hinds, Sidney R; Hodges, Cooper B; Hovenden, Elizabeth S; Irimia, Andrei; Kenney, Kimbra; Koerte, Inga K; Kremen, William S; Levin, Harvey S; Lindsey, Hannah M; Morey, Rajendra A; Newsome, Mary R; Ollinger, John; Pugh, Mary Jo; Scheibel, Randall S; Shenton, Martha E; Sullivan, Danielle R; Taylor, Brian A; Troyanskaya, Maya; Velez, Carmen; Wade, Benjamin Sc; Wang, Xin; Ware, Ashley L; Zafonte, Ross; Thompson, Paul M; Wilde, Elisabeth A (Springer New York, 2021-04)
    Traumatic brain injury (TBI) is common among military personnel and the civilian population and is often followed by a heterogeneous array of clinical, cognitive, behavioral, mood, and neuroimaging changes. Unlike many ...
  • Hospital volume is associated with postoperative mortality after radical cystectomy for treatment of bladder cancer 
    Richters, A; Ripping, T M; Kiemeney, L A; Leliveld, A M; van Rhijn, B W G; Oddens, J R; van Moorselaar, R J A; Goossens-Laan, C A; Meijer, R P; Boormans, J; Witjes, J A; Aben, K K H; BlaZIB Study Group (Wiley-Blackwell, 2021-10)
    OBJECTIVE: To contribute to the debate regarding the minimum volume of radical cystectomies (RCs) that a hospital should perform by evaluating the association between hospital volume (HV) and postoperative mortality. ...
  • Study protocol of a randomized, double-blind, placebo-controlled, multi-center trial to treat antipsychotic-induced weight gain: the Metformin-Lifestyle in antipsychotic users (MELIA) trial 
    de Boer, Nini; Guloksuz, Sinan; van Baal, Caroline; Willebrands, Leonie; Deenik, Jeroen; Vinkers, Christiaan H.; Rossum, Inge Winter van; Zinkstok, Janneke; Wilting, Ingeborg; Zantvoord, Jasper B.; Backx, Frank; Swildens, Wilma E.; Schouw, Marieke; Bogers, Jan; Hulshof, Folkwin; de Knijff, Rudolf; Duindam, Peter; Veereschild, Mike; Bak, Maarten; Frederix, Geert; de Haan, Lieuwe; van Os, Jim; Cahn, Wiepke; Luykx, Jurjen J. (BioMed Central, 2021-12)
    BACKGROUND: Antipsychotic-induced Weight Gain (AiWG) is a debilitating and common adverse effect of antipsychotics. AiWG negatively impacts life expectancy, quality of life, treatment adherence, likelihood of developing ...
  • Internal mammary and medial supraclavicular lymph node chain irradiation in stage I-III breast cancer (EORTC 22922/10925): 15-year results of a randomised, phase 3 trial 
    European Organisation for Research and Treatment of Cancer Radiation Oncology and Breast Cancer Groups (Elsevier Limited, 2020-12)
    BACKGROUND: 10-year results from several studies showed improved disease-free survival and distant metastasis-free survival, reduced breast cancer-related mortality, and variable effects on overall survival with the addition ...
  • The adult human subventricular zone: partial ependymal coverage and proliferative capacity of cerebrospinal fluid 
    de Sonnaville, Sophia F A M; van Strien, Miriam E; Middeldorp, Jinte; Sluijs, Jacqueline A; van den Berge, Simone A; Moeton, Martina; Donega, Vanessa; van Berkel, Annemiek; Deering, Tasmin; De Filippis, Lidia; Vescovi, Angelo L; Aronica, Eleonora; Glass, Rainer; van de Berg, Wilma D J; Swaab, Dick F; Robe, Pierre A; Hol, Elly M (Oxford University Press, 2020)
    Neurogenesis continues throughout adulthood in specialized regions of the brain. One of these regions is the subventricular zone. During brain development, neurogenesis is regulated by a complex interplay of intrinsic and ...
  • A loss of mature microglial markers without immune activation in schizophrenia 
    Snijders, Gijsje J.L.J.; van Zuiden, Welmoed; Sneeboer, Marjolein A.M.; Berdenis van Berlekom, Amber; van der Geest, Astrid T.; Schnieder, Tatiana; MacIntyre, Donald J.M.; Hol, Elly M.; Kahn, René S.; de Witte, Lot D. (John Wiley & Sons Inc., 2021-05)
    Microglia, the immune cells of the brain, are important for neurodevelopment and have been hypothesized to play a role in the pathogenesis of schizophrenia (SCZ). Although previous postmortem studies pointed toward presence ...
  • Status of theory use in self-care research 
    Jaarsma, Tiny; Westland, Heleen; Vellone, Ercole; Freedland, Kenneth E.; Schröder, Carin; Trappenburg, Jaap C.A.; Strömberg, Anna; Riegel, Barbara (Multidisciplinary Digital Publishing Institute (MDPI), 2020-12-02)
    Background: Theories can provide a foundation to explain behavior, investigate relationships, and to predict the effect of interventions. The aim of the study was to clarify the use of theories in studies testing interventions ...
  • De novo variants in POLR3B cause ataxia, spasticity, and demyelinating neuropathy 
    Djordjevic, Djurdja; Pinard, Maxime; Gauthier, Marie-Soleil; Smith-Hicks, Constance; Hoffman, Trevor L; Wolf, Nicole I; Oegema, Renske; van Binsbergen, Ellen; Baskin, Berivan; Bernard, Geneviève; Fribourg, Sébastien; Coulombe, Benoit; Yoon, Grace (Cell Press, 2021-01-07)
    POLR3B encodes the second-largest catalytic subunit of RNA polymerase III, an enzyme involved in transcription. Bi-allelic pathogenic variants in POLR3B are a well-established cause of hypomyelinating leukodystrophy. We ...
  • Effectiveness of a crossover prosthetic foot in active children with a congenital lower limb deficiency: an explorative study 
    Verheul, Floor Jacoba Marie Georgette; Verschuren, Olaf; Zwinkels, Maremka; Herwegh, Mariska; Michielsen, Anka; de Haan, Marieke; van Wijk, Iris (Lippincott Williams & Wilkins, 2020-10-01)
    Background: Children with lower limb prostheses cannot always keep up with their peers during active play. A pediatric crossover foot may be a promising prosthetic alternative for children engaging in high-intensity movements ...
  • Sleep health practices and sleep knowledge among healthcare professionals in Dutch paediatric rehabilitation 
    Hulst, Raquel Y.; Pillen, Sigrid; Voorman, Jeanine M.; Rave, Neele; Visser-Meily, Johanna M.A.; Verschuren, Olaf (Wiley-Blackwell, 2020-11-01)
    Background: Sleep disorders are highly prevalent in children with neurodisabilities, yet they seem under-recognized in paediatric rehabilitation settings. The aim of this study was to assess among two groups of healthcare ...
  • Feasibility, reproducibility and validity of the 10 meter Shuttle Test in mild to moderately impaired people with stroke 
    Wittink, Harriet; Blatter, Tim; Outermans, Jacqueline; Volkers, Mariella; Westers, Paul; Verschuren, Olaf (Public Library of Science, 2020-10)
    Background There currently is no field test available for measuring maximal exercise capacity in people with stroke. Objective To determine the feasibility, reproducibility and validity of the Shuttle Test (ST) to measure ...
  • The formula for health and well-being in individuals with cerebral palsy: Cross-sectional data on physical activity, sleep, and nutrition 
    McPhee, Patrick G.; Verschuren, Olaf; Peterson, Mark D.; Tang, Ada; Gorter, Jan Willem (Korean Academy of Rehabilitation Medicine, 2020-08-01)
    Objective To determine physical activity, sleep, and nutrition patterns in individuals with cerebral palsy (CP) and investigate the association of Gross Motor Function Classification System (GMFCS) and age with these health ...
  • A rapid review of evidence and recommendations from the SIOPE radiation oncology working group to help mitigate for reduced paediatric radiotherapy capacity during the COVID-19 pandemic or other crises 
    Janssens, Geert O; Mandeville, Henry C; Timmermann, Beate; Maduro, John H; Alapetite, Claire; Padovani, Laetitia; Horan, Gail; Lassen-Ramshad, Yasmin; Dieckmann, Karin; Ruebe, Christian; Thorp, Nicky; Gandola, Lorenza; Ajithkumar, Thankamma; Boterberg, Tom (Elsevier Ireland Ltd, 2020-07)
    OBJECTIVE: To derive evidence-based recommendations for the optimal utilisation of resources during unexpected shortage of radiotherapy capacity. METHODS AND MATERIALS: We have undertaken a rapid review of published ...
  • Surrogate-free machine learning-based organ dose reconstruction for pediatric abdominal radiotherapy 
    Virgolin, Marco; Wang, Ziyuan; Balgobind, Brian; van Dijk, Irma; Wiersma, Jan; Kroon, Petra S; Janssens, Geert O; van Herk, Marcel; Hodgson, David C; Zadravec Zaletel, Lorna; Rasch, Coen; Bel, Arjan; Bosman, Peter A N; Alderliesten, Tanja (IOP Publishing Ltd., 2020-12-21)
    To study radiotherapy-related adverse effects, detailed dose information (3D distribution) is needed for accurate dose-effect modeling. For childhood cancer survivors who underwent radiotherapy in the pre-CT era, only 2D ...