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Now showing items 17201-17220 of 40729

Heart failure etiology and risk of right heart failure in adult left ventricular assist device support: the European Registry for Patients with Mechanical Circulatory Support (EUROMACS)

Løgstrup, Brian Bridal; Nemec, Petr; Schoenrath, Felix; Gummert, Jan; Pya, Yuri; Potapov, Evgenij; Netuka, Ivan; Ramjankhan, Faiz; Parner, Eric Thorlund; De By, Theo; Eiskjaer, Hans (Informa Healthcare, 2020-09-02)

Objectives: Development of right ventricular failure (RVF) after left ventricular assist device (LVAD) implantation remains a leading cause of perioperative morbidity, end-organ dysfunction and mortality. The objective of ...
Change in National Dosing Advice of Nitroprusside After Potentially Fatal Cyanide Intoxication

Bothof, Guido; van Rhee, Koen; Koomen, Erik; Veldhoen, ES (Springer, 2020-04-28)

The aim of this brief communication is to provide a short overview of cyanide intoxication following infusion of sodium nitroprusside (SNP). SNP is a fast-acting antihypertensive drug frequently used in of hypertensive ...
Feasibility of the new sutureless excimer laser-assisted non-occlusive anastomosis clip in a rabbit model

de Boer, B; van Doormaal, T P C; Stecher, D; Redegeld, S; Tulleken, C A F; Regli, L; van der Zwan, A (Springer, 2020-01-01)

Background: The excimer laser-assisted non-occlusive anastomosis (ELANA) technique facilitates the construction of anastomoses without temporary occlusion of the recipient artery. Experiments aimed at simplifying the ...
Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits

Heuschkel, Marina A; Skenteris, Nikolaos T; Hutcheson, Joshua D; van der Valk, Dewy D; Bremer, Juliane; Goody, Philip; Hjortnaes, Jesper; Jansen, Felix; Bouten, Carlijn V C; van den Bogaerdt, Antoon; Matic, Ljubica; Marx, Nikolaus; Goettsch, Claudia (Multidisciplinary Digital Publishing Institute (MDPI), 2020-10)

Calcific aortic valve disease (CAVD) is the most prevalent valvular heart disease in the developed world, yet no pharmacological therapy exists. Here, we hypothesize that the integration of multiple omic data represents ...
Pancreatic beta-Cell-Specific Deletion of VPS41 Causes Diabetes Due to Defects in Insulin Secretion

Burns, Christian H; Yau, Belinda; Rodriguez, Anjelica; Triplett, Jenna; Maslar, Drew; An, You Sun; van der Welle, Reini E N; Kossina, Ross G; Fisher, Max R; Strout, Gregory W; Bayguinov, Peter O; Veenendaal, Tineke; Chitayat, David; Fitzpatrick, James A J; Klumperman, Judith; Kebede, Melkam A; Asensio, Cedric S (American Diabetes Association Inc., 2021-02-01)

Insulin secretory granules (SGs) mediate the regulated secretion of insulin, which is essential for glucose homeostasis. The basic machinery responsible for this regulated exocytosis consists of specific proteins present ...
A randomized experimental study to test the effects of discussing uncertainty during cancer genetic counseling: different strategies, different outcomes?

Medendorp, Niki M; Hillen, Marij A; Visser, Leonie N C; Aalfs, Cora M; Duijkers, Floor A M; van Engelen, Klaartje; Ausems, Margreet G E M; Verhoef, Senno; Stiggelbout, Anne M; Smets, Ellen M A (Springer Nature, 2021-05)

Uncertainty is increasingly discussed during genetic counseling due to innovative techniques, e.g., multigene panel testing. Discussions about uncertainty may impact counselees variably, depending on counselors' communication ...
A study protocol for quantifying patient preferences in neuromuscular disorders: a case study of the IMI Prefer project.

Jimenez-Moreno, A.C.; Pinto, C.A.; Levitan, Bennett; Whichello, Chiara; Dyer, Christine; Van Overbeeke, Eline; de Bekker-Grob, Esther; Smith, Ian; Huys, Isabelle; Viberg Johansson, Jennifer; Adcock, Kate; Bullock, Kristin; Soekhai, Vikas; Yuan, Zhong; Lochmüller, Hanns; de Wit, Ardine (G.A.); Gorman, G. (F1000 Research Ltd., 2020)

Objectives: Patient preference studies are increasingly used to inform decision-making during the medical product lifecycle but are rarely used to inform early stages of drug development. The primary aim of this study is ...
Roto-translation equivariant convolutional networks: Application to histopathology image analysis

Lafarge, Maxime W; Bekkers, Erik J; Pluim, Josien P W; Duits, Remco; Veta, Mitko (Elsevier, 2021-02)

Rotation-invariance is a desired property of machine-learning models for medical image analysis and in particular for computational pathology applications. We propose a framework to encode the geometric structure of the ...
Unmet information needs of men with breast cancer and health professionals

Bootsma, Tom I; Duijveman, Petra; Pijpe, Anouk; Scheelings, Pernilla C; Witkamp, Arjen J; Bleiker, Eveline M A (John Wiley & Sons Inc., 2020-05-01)

OBJECTIVE: Male breast cancer (MBC) is rare. Information about breast cancer is usually designed for female patients. However, in males this disease and some side effects differ from its female counterpart. Therefore, there ...
Incidence of complications in secondary alveolar bone grafting of bilateral clefts with premaxillary osteotomy: a retrospective cohort study

Bittermann, Gerhard K P; van Es, Robert J J; de Ruiter, Adrianus P; Frank, Michael H; Bittermann, Arnold J N; van der Molen, Aebele B Mink; Koole, Ron; Rosenberg, Antoine J W P (Springer-Verlag, 2020-02)

OBJECTIVE: To evaluate factors affecting incidence of complications after secondary alveolar bone grafting with premaxillary osteotomy (SABG + PO) in children with complete bilateral cleft of lip and palate (BCLP). MATERIALS ...
Real-world non-interventional long-term post-authorisation safety study of ruxolitinib in myelofibrosis

Barraco, Fiorenza; Greil, Richard; Herbrecht, Raoul; Schmidt, Burkhard; Reiter, Andreas; Willenbacher, Wolfgang; Raymakers, Reinier; Liersch, Rüdiger; Wroclawska, Monika; Pack, Robert; Burock, Karin; Karumanchi, Divyadeep; Gisslinger, Heinz (Wiley-Blackwell, 2020-12)

Primary objective of this non-interventional, post-authorisation safety study was to provide real-world safety data [incidence of adverse drug reactions (ADRs)/serious adverse events (SAEs)] on adult patients with myelofibrosis ...
The prognostic value of automated coronary calcium derived by a deep learning approach on non-ECG gated CT images from 82Rb-PET/CT myocardial perfusion imaging

Dekker, Mirthe; Waissi, Farahnaz; Bank, Ingrid E M; Isgum, Ivana; Scholtens, Asbjørn M; Velthuis, Birgitta K; Pasterkamp, Gerard; de Winter, Robbert J; Mosterd, Arend; Timmers, Leo; de Kleijn, Dominique P V (Elsevier Ireland Ltd, 2021-04-15)

Background: Assessment of both coronary artery calcium(CAC) scores and myocardial perfusion imaging(MPI) in patients suspected of coronary artery disease(CAD) provides incremental prognostic information. We used an automated ...
Trends in delayed breast cancer diagnosis after recall at screening mammography

Lameijer, J R C; Voogd, A C; Broeders, M J M; Pijnappel, R M; Setz-Pels, W; Strobbe, L J; Jansen, F H; Tjan-Heijnen, V C G; Duijm, L E M (Elsevier Ireland Ltd, 2021-03)

OBJECTIVES: To determine the extent and characteristics of delay in breast cancer diagnosis in women recalled at screening mammography. METHODS: We included a consecutive series of 817,656 screens of women who received ...
Unmet expectations in prostate cancer patients and their association with decision regret

Wollersheim, Barbara M; van Stam, Marie-Anne; Bosch, Ruud J L H; Pos, Floris J; Tillier, Corinne N; van der Poel, Henk G; Aaronson, Neil K (Springer, 2020-10-01)

PURPOSE: Information about prostate cancer patients' experiences with their treatment is crucial to optimize shared decision-making. This study examined unmet expectations in prostate cancer patients and their association ...
Significance of Examined Lymph Node Number in Accurate Staging and Long-term Survival in Resected Stage I-II Pancreatic Cancer-More is Better?: A Large International Population-based Cohort Study

Huang, Lei; Jansen, Lina; Balavarca, Yesilda; van der Geest, Lydia; Lemmens, Valery; Groot Koerkamp, Bas; van Santvoort, Hjalmar C; Grützmann, Robert; Besselink, Marc G; Schrotz-King, Petra; Brenner, Hermann (Lippincott Williams & Wilkins, 2021-12-01)

OBJECTIVE: This large international cohort study aimed to investigate the associations of examined lymph node (ELN) number with accurate staging and long-term survival in pancreatic adenocarcinoma (PaC) and to robustly ...
Pancreatic resection in the pediatric, adolescent and young adult population: nationwide analysis on complications

Dutch Pancreatic Cancer Group (John Wiley & Sons Inc., 2021-08)

Background: The aim of this study was to determine pancreatic surgery specific short- and long-term complications of pediatric, adolescent and young adult (PAYA) patients who underwent pancreatic resection, as compared to ...
Pain patterns in chronic pancreatitis: a nationwide longitudinal cohort study

Dutch Pancreatitis Study Group (BMJ Publishing Group, 2021-09-01)

OBJECTIVE: Pain in chronic pancreatitis is subdivided in a continuous or intermittent pattern, each thought to represent a different entity, requiring specific treatment. Because evidence is missing, we studied pain patterns ...
Nationwide practice and outcomes of endoscopic biliary drainage in resectable pancreatic head and periampullary cancer

Dutch Pancreatic Cancer Group (John Wiley & Sons Inc., 2021-02)

BACKGROUND: Guidelines advise self-expanding metal stents (SEMS) over plastic stents in preoperative endoscopic biliary drainage (EBD) for malignant extrahepatic biliary obstruction. This study aims to assess nationwide ...
Association between nutritional profiles of foods underlying Nutri-Score front-of-pack labels and mortality: EPIC cohort study in 10 European countries

EPIC (BMJ Publishing Group, 2020-09-16)

Objective To determine if the Food Standards Agency nutrient profiling system (FSAm-NPS), which grades the nutritional quality of food products and is used to derive the Nutri-Score front-of-packet label to guide consumers ...
Transatlantic registries of pancreatic surgery in the United States of America, Germany, the Netherlands, and Sweden: Comparing design, variables, patients, treatment strategies, and outcomes

Global Audits on Pancreatic Surgery Group (GAPASURG) (Mosby Inc., 2021-02)

Background: Registries of pancreatic surgery have become increasingly popular as they facilitate both quality improvement and clinical research. We aimed to compare registries for design, variables collected, patient ...

Now showing items 17201-17220 of 40729