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UMC Repository: Recent submissions

  • Activation response and functional connectivity change in rat cortex after bilateral transcranial direct current stimulation—An exploratory study 
    Boonzaier, Julia; Straathof, Milou; Ardesch, Dirk Jan; van der Toorn, Annette; van Vliet, Gerard; van Heijningen, Caroline L.; Otte, Willem M.; Dijkhuizen, Rick M. (Wiley-Liss Inc., 2021-05)
    Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique implicated as a promising adjunct therapy to improve motor function through the neuromodulation of brain networks. Particularly ...
  • Axial slicing versus bivalving in the pathological examination of pancreatoduodenectomy specimens (APOLLO): a multicentre randomized controlled trial 
    van Roessel, Stijn; Soer, Eline C.; van Dieren, Susan; Koens, Lianne; van Velthuysen, Marie Louise F.; Doukas, Michael; Koerkamp, Bas Groot; Sarasqueta, Arantza Farina; Bronkhorst, Carolien M.; Raicu, G. Mihaela; Kuijpers, Karel C.; Seldenrijk, Cornelis A.; van Santvoort, Hjalmar C.; Molenaar, I. Quintus; van der Post, Rachel S.; Stommel, Martijn W. J.; Busch, Olivier R.; Besselink, Marc G.; Brosens, Lodewijk A. A.; Verheij, Joanne (John Wiley & Sons Inc., 2021-09)
    BACKGROUND: In pancreatoduodenectomy specimens, dissection method may affect the assessment of primary tumour origin (i.e. pancreatic, distal bile duct or ampullary adenocarcinoma), which is primarily determined macroscopically. ...
  • Predictive factors for surgical treatment in preterm neonates with necrotizing enterocolitis: a multicenter case-control study 
    El Manouni El Hassani, Sofia; Niemarkt, Hendrik J; Derikx, Joep P M; Berkhout, Daniel J C; Ballón, Andrea E; de Graaf, Margot; de Boode, Willem P; Cossey, Veerle; Hulzebos, Christian V; van Kaam, Anton H; Kramer, Boris W; van Lingen, Richard A; Vijlbrief, Daniel C; van Weissenbruch, Mirjam M; Benninga, Marc A; de Boer, Nanne K H; de Meij, Tim G J (Springer-Verlag, 2021-02)
    Necrotizing enterocolitis (NEC) is one of the most common and lethal gastrointestinal diseases in preterm infants. Early recognition of infants in need for surgical intervention might enable early intervention. In this ...
  • Bibliotherapy for Sexual Dysfunctions: A Systematic Review and Meta-Analysis 
    van Lankveld, Jacques J D M; van de Wetering, Fleur T; Wylie, Kevan; Scholten, Rob J P M (Wiley-Blackwell, 2021-03)
    AIM: The objective of this study was to assess the efficacy of bibliotherapy for sexual dysfunctions, when compared with no treatment and compared with other interventions. METHODS: MEDLINE, EMBASE, and PsycINFO were ...
  • Endovascular Treatment for Basilar Artery Occlusion: A Systematic Review and Meta-analysis 
    Katsanos, Aristeidis H; Safouris, Apostolos; Nikolakopoulos, Stavros; Mavridis, Dimitris; Goyal, Nitin; Psychogios, Marios N; Magoufis, Georgios; Krogias, Christos; Catanese, Luciana; Van Adel, Brian; Raphaeli, Guy; Sarraj, Amrou; Themistocleous, Marios; Kararizou, Evangelia; Turc, Guillaume; Arthur, Adam; Alexandrov, Andrei V; Tsivgoulis, Georgios (Wiley-Blackwell, 2021-06)
    Background and purpose: Independent randomized controlled clinical trials (RCTs) have provided robust evidence for endovascular treatment (EVT) as the standard of care treatment for acute large vessel occlusions in the ...
  • An old friend who has overstayed their welcome: the ALSFRS-R total score as primary endpoint for ALS clinical trials 
    van Eijk, Ruben P A; de Jongh, Adriaan D; Nikolakopoulos, Stavros; McDermott, Christopher J; Eijkemans, Marinus J C; Roes, Kit C B; van den Berg, Leonard H (Informa Healthcare, 2021-05)
    Objective: The ALSFRS-R is limited by multidimensionality, which originates from the summation of various subscales. This prevents a direct comparison between patients with identical total scores. We aim to evaluate how ...
  • Synthetic MRI demonstrates prolonged regional relaxation times in the brain of preterm born neonates with severe postnatal morbidity 
    Vanderhasselt, Tim; Zolfaghari, Roya; Naeyaert, Maarten; Dudink, Jeroen; Buls, Nico; Allemeersch, Gert-Jan; Raeymaekers, Hubert; Cools, Filip; de Mey, Johan (Elsevier, 2021-01)
    Background: To identify preterm infants at risk for neurodevelopment impairment that might benefit from early neurorehabilitation, early prognostic biomarkers of future outcomes are needed. Objective: To determine whether ...
  • Performing newborn life support in advance of neonatal advanced life support course-back to basics? 
    Hundscheid, Tim; Bruinenberg, Jos; Dudink, Jeroen; de Jonge, Rogier; Hogeveen, Marije (Springer-Verlag, 2021-05)
    In this retrospective analysis, the Newborn Life Support (NLS) test scenario performance of participants of the Dutch Neonatal Advanced Life Support (NALS) course was assessed. Characteristics of participants and total ...
  • Cerebellar volumes and language functions in school-aged children born very preterm 
    Stipdonk, Lottie W; Boumeester, Marlijne; Pieterman, Kay J; Franken, Marie-Christine J P; Rosmalen, Joost van; Reiss, Irwin K; Dudink, Jeroen (Lippincott Williams & Wilkins, 2021-10)
    BACKGROUND: Volumes of cerebellar posterior lobes have been associated with cognitive skills, such as language functioning. Children born very preterm (VPT) often have language problems. However, only total cerebellar ...
  • BIO FOr CARE: biomarkers of hypertrophic cardiomyopathy development and progression in carriers of Dutch founder truncating MYBPC3 variants-design and status 
    Jansen, M; Christiaans, I; van der Crabben, S N; Michels, M; Huurman, R; Hoedemaekers, Y M; Dooijes, D; Jongbloed, J D H; Boven, L G; Lekanne Deprez, R H; Wilde, A A M; Jans, J J M; van der Velden, J; de Boer, R A; van Tintelen, J P; Asselbergs, F W; Baas, A F (Bohn Stafleu van Loghum, 2021-06)
    BACKGROUND: Hypertrophic cardiomyopathy (HCM) is the most prevalent monogenic heart disease, commonly caused by truncating variants in the MYBPC3 gene. HCM is an important cause of sudden cardiac death; however, overall ...
  • Risk stratification and subclinical phenotyping of dilated and/or arrhythmogenic cardiomyopathy mutation-positive relatives: CVON eDETECT consortium 
    Roudijk, R W; Taha, K; Bourfiss, M; Loh, Peter; van den Heuvel, L; Boonstra, M J; van Lint, F; van der Voorn, S M; Te Riele, A S J M; Bosman, L P; Christiaans, I; van Veen, T A B; Remme, Carol Ann; van den Berg, M P; van Tintelen, J P; Asselbergs, F W (Bohn Stafleu van Loghum, 2021-06)
    In relatives of index patients with dilated cardiomyopathy and arrhythmogenic cardiomyopathy, early detection of disease onset is essential to prevent sudden cardiac death and facilitate early treatment of heart failure. ...
  • Cell-density independent increased lymphocyte production and loss rates post-autologous HSCT 
    Baliu Piqué, Mariona; van Hoeven, Vera; Drylewicz, Julia; van der Wagen, Lotte E; Janssen, Anke; Otto, Sigrid A; van Zelm, Menno C; de Boer, Rob J; Kuball, Jürgen Jhe; Borghans, Jose Am; Tesselaar, Kiki (eLife Sciences Publications, 2021-02-04)
    Lymphocyte numbers need to be quite tightly regulated. It is generally assumed that lymphocyte production and lifespan increase homeostatically when lymphocyte numbers are low and, vice versa, return to normal once cell ...
  • Electrocardiographic and echocardiographic abnormalities in urban African people living with HIV in South Africa 
    Roozen, Geert V T; Meel, Ruchika; Peper, Joyce; Venter, William D F; Barth, Roos E; Grobbee, Diederick E; Klipstein-Grobusch, Kerstin; Vos, Alinda G (Public Library of Science, 2021-02-02)
    Background Studies from high income countries report that HIV-positive people have an impaired systolic and diastolic cardiac function compared to HIV-negative people. It is unclear if results can be translated directly ...
  • Anthropometric indices and their cut-off points in relation to type 2 diabetes among Ghanaian migrants and non-migrants: The RODAM study 
    Darko, Samuel N; Meeks, Karlijn A C; K B A Owiredu, William; Laing, Edwin F; Boateng, Daniel; Beune, Erik; Addo, Juliet; de-Graft Aikins, Ama; Bahendeka, Silver; Mockenhaupt, Frank; Spranger, Joachim; Agyei-Baffour, Peter; Klipstein-Grobusch, Kerstin; Smeeth, Liam; Agyemang, Charles; Owusu-Dabo, Ellis (Elsevier Ireland Ltd, 2021-03)
    Aims: To compare body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) as determinants of type 2 diabetes (T2DM) and determine optimal cut-offs in a sub-Saharan African population. Methods: Data from ...
  • Poor cardiovascular health is associated with subclinical atherosclerosis in apparently healthy sub-Saharan African populations: an H3Africa AWI-Gen study 
    Nonterah, Engelbert A; Crowther, Nigel J; Oduro, Abraham; Agongo, Godfred; Micklesfield, Lisa K; Boua, Palwendé R; Choma, Solomon S R; Mohamed, Shukri F; Sorgho, Herman; Tollman, Stephen M; Norris, Shane A; Raal, Frederick J; Grobbee, Diederick E; Ramsay, Michelé; Bots, Michiel L; Klipstein-Grobusch, Kerstin; as part of the H3Africa AWI-Gen study (BioMed Central Ltd., 2021-02-10)
    Background: The cardiovascular health index (CVHI) introduced by the American Heart Association is a valid, accessible, simple, and translatable metric for monitoring cardiovascular health in a population. Components of ...
  • Early detection of severe injuries after major trauma by immediate total-body CT scouts 
    Treskes, K.; Russchen, M. J. A. M.; Beenen, L. F. M.; de Jong, V. M.; Kolkman, S.; de Bruin, I. G. J. M.; Dijkgraaf, M. G. W.; Van Lieshout, E. M. M.; Saltzherr, T. P.; Goslings, J. C. (Elsevier Limited, 2020-01)
    Introduction: Evaluation of immediate total-body CT (iTBCT) scouts during primary trauma care could be clinically relevant for early detection and treatment of specific major injuries. The aim of this study was to determine ...
  • Automated non-contact detection of central apneas using video 
    Geertsema, Evelien E.; Visser, Gerhard H.; Sander, Josemir W.; Kalitzin, Stiliyan N. (Elsevier, 2020-01)
    Central apneas occurring in the aftermath of epileptic seizures may lead to sudden death. Contact-sensors currently used to detect apneas are not always suitable or tolerated. We developed a robust automated non-contact ...
  • Altered splenic [Zr-89]Zr-rituximab uptake in patients with interstitial lung disease not responding to rituximab: could this indicate a splenic immune-mediated mechanism? 
    Adams, Human; Meek, Bob; van de Garde, Ewoudt M. W.; van Moorsel, Coline H. M.; Vugts, Danielle J.; Keijsers, Ruth G.; Grutters, Jan C. (e-Century Publishing Corporation, 2020-08)
    Rituximab (RTX) for immune-mediated inflammatory disease (IMID) with interstitial pneumonitis (IP) results in non-response in about a third of patients for reasons not well understood. Complete peripheral B-cell depletion ...
  • Limited effect of duration of CMV infection on adaptive immunity and frailty: insights from a 27-year-long longitudinal study 
    Samson, Leonard Daniel; van den Berg, Sara P. H.; Engelfriet, Peter; Boots, Annemieke M. H.; Hendriks, Marion; de Rond, Lia G. H.; de Zeeuw-Brouwer, Mary-Iene; Verschuren, W. M. Monique; Borghans, Jose A. M.; Buisman, Anne-Marie; van Baarle, Debbie (Nature Publishing Group, 2020)
    Objectives: Cytomegalovirus infection is thought to affect the immune system and to impact general health during ageing. Higher CMV-specific antibody levels in the elderly are generally assumed to reflect experienced viral ...
  • Global incidence and profile of ameloblastoma: A systematic review and meta-analysis 
    Hendra, Faqi Nurdiansyah; Van Cann, Ellen M.; Helder, Marco N.; Ruslin, Muhammad; de Visscher, Jan G.; Forouzanfar, Tymour; de Vet, Henrica C. W. (Wiley-Blackwell, 2020-01)
    Objectives: To evaluate the global incidence of ameloblastoma and to provide a profile of ameloblastoma patients. Material and Methods: A systematic review and meta-analysis was conducted. Searches were performed in PubMed, ...