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Now showing items 16741-16760 of 40729

Substitution of pure fruit juice for fruit and sugar-sweetened beverages and cardiometabolic risk in European Prospective Investigation into Cancer and Nutrition (EPIC)-NL:: a prospective cohort study

Scheffers, Floor R; Boer, Jolanda M A; Wijga, Alet H; van der Schouw, Yvonne T; Smit, Henriëtte A; Verschuren, W M Monique (Cambridge University Press, 2022-06)

Objective: Dietary guidelines on pure fruit juice differ between countries regarding the question whether pure fruit juice (without added sugars) is an acceptable substitute for fruit or should be avoided because of its ...
A network perspective on suicidal behavior: Understanding suicidality as a complex system

de Beurs, Derek; Bockting, Claudi; Kerkhof, Ad; Scheepers, Floortje; O’Connor, Rory; Penninx, Brenda; van de Leemput, Ingrid (Wiley-Blackwell, 2021-02)

BACKGROUND: Suicidal behavior is the result of complex interactions between many different factors that change over time. A network perspective may improve our understanding of these complex dynamics. Within the network ...
Individual risk calculator to predict lymph node metastases in patients with submucosal (T1b) esophageal adenocarcinoma: a multicenter cohort study

Gotink, Annieke W; van de Ven, Steffi Elisabeth Maria; Ten Kate, Fiebo Jw; Nieboer, Daan; Suzuki, Lucia; Weusten, Bas L A M; Brosens, Lodewijk A A; van Hillegersberg, Richard; Alvarez Herrero, Lorenza; Seldenrijk, C A; Alkhalaf, Alaa; Moll, F C P; Schoon, Erik J; van Lijnschoten, Ineke; Tang, Thjon J; van der Valk, Hans; Nagengast, Wouter B; Kats-Ugurlu, Gursah; Plukker, John T M; Houben, Martin H M G; van der Laan, J S; Pouw, Roos E; Bergman, Jacques J G H M; Meijer, Sybren L; van Berge Henegouwen, Mark I; Wijnhoven, Bas P L; de Jonge, Pieter J F; Doukas, Michael; Bruno, Marco J; Biermann, Katharina; Koch, Arjun Dave (Georg Thieme Verlag, 2022-02)

BACKGROUND: Lymph node metastasis (LNM) is possible after endoscopic resection of early esophageal adenocarcinoma (EAC). This study aimed to develop and internally validate a prediction model that estimates the individual ...
Reply to McDonald and colleagues: "Can endoscopic ultrasound-guided gastroenterostomy be used as first line modality for endoscopic management of malignant gastric outlet obstruction?"

Kastelijn, Janine B; Moons, Leon M G; Vleggaar, Frank P (Georg Thieme Verlag, 2021-03)
Integrale zorg voor patiënten met atriumfibrilleren: Is toepassing in de huisartsenpraktijk veilig?

Van den Dries, Carline J.; Van Doorn, Sander; Rutten, Frans H.; Oudega, Ruud; Van de Leur, Sjef J.C.M.; Elvan, Arif; Grave, Lisa Oude; Bilo, Henk J.G.; Moons, Karel G.M.; Hoes, Arno W.; Geersing, Geert Jan (Bohn Stafleu van Loghum, 2021-01-01)
Systemic treatment in atopic dermatitis after 2018: from experienced-based treatment to evidence-based treatment?

de Bruin-Weller, M (Wiley-Blackwell, 2020-12)
Patient-Reported Ocular Disorders and Symptoms in Adults with Moderate-to-Severe Atopic Dermatitis: Screening and Baseline Survey Data from a Clinical Trial

Weyne, Jonathan; Blauvelt, Andrew; de Bruin-Weller, Marjolein; Prens, Errol; Asbell, Penny; Sierka, Debra; Chen, Zhen; Shumel, Brad (Springer-Verlag, 2020-12)

INTRODUCTION: Patients with atopic dermatitis (AD) have a greater risk of conjunctivitis and other ocular surface disorders than the general population. We evaluated the burden of ocular surface disorders and related ...
Twelve years of circulatory extracorporeal life support at the University Medical Centre Utrecht

Meuwese, C L; Hermens, J A; de Haan, M; Braithwaite, S A; Ramjankhan, F; Buijsrogge, M P; de Jonge, N; Kirkels, J H; de Jong, M; Pasma, W; Vromen-Wijsman, J L P; Kraaijeveld, A O; de Waal, E E; Torn, E; Platenkamp, M; van der Heijden, J J; Cremer, O L; van Dijk, D; Donker, D W (Bohn Stafleu van Loghum, 2021-03-06)

INTRODUCTION: Circulatory extracorporeal life support (ECLS) has been performed at the University Medical Centre Utrecht for 12 years. During this time, case mix, indications, ECLS set-ups and outcomes seem to have ...
The predictive validity for mortality of the driving pressure and the mechanical power of ventilation

MARS Consortium (Springer Science + Business Media, 2020-12-18)

Background: Outcome prediction in critically ill patients under invasive ventilation remains extremely challenging. The driving pressure (ΔP) and the mechanical power of ventilation (MP) are associated with patient-centered ...
Prognostic classification based on P/F and PEEP in invasively ventilated ICU patients with hypoxemia-insights from the MARS study

MARS Consortium (Springer Science + Business Media, 2020-12-18)

Background: Outcome prediction in patients with acute respiratory distress syndrome (ARDS) greatly improves when patients are reclassified based on predefined arterial oxygen partial pressure to fractional inspired oxygen ...
Pulmonary congestion and mortality during venoarterial extracorporeal membrane oxygenation (VA-ECMO): does time matter?

van der Wal, Pieter S; Zwetsloot, Peter-Paul; Cremer, Olaf L; Donker, Dirk W; Meuwese, Christiaan L (Elsevier, 2021-04)
Consumptive coagulopathy is associated with a disturbed host response in patients with sepsis

MARS Consortium (Wiley-Blackwell, 2021-04)

BACKGROUND: A prolonged prothrombin time (PT) is a common feature in sepsis indicating consumptive coagulopathy. OBJECTIVES: To determine the association between a prolonged PT and aberrations in other host response ...
Biological Subphenotypes of Acute Respiratory Distress Syndrome Show Prognostic Enrichment in Mechanically Ventilated Patients without Acute Respiratory Distress Syndrome

MARS Consortium (American Thoracic Society, 2021-06-15)

Rationale: Recent studies showed that biological subphenotypes in acute respiratory distress syndrome (ARDS) provide prognostic enrichment and show potential for predictive enrichment. Objectives: To determine whether these ...
Large-scale ICU data sharing for global collaboration: the first 1633 critically ill COVID-19 patients in the Dutch Data Warehouse

Fleuren, Lucas M; de Bruin, Daan P; Tonutti, Michele; Lalisang, Robbert C A; Elbers, Paul W G; Dutch ICU Data Sharing Collaborators (Springer-Verlag, 2021-04)
Pooled safety analysis of baricitinib in adult patients with atopic dermatitis from 8 randomized clinical trials

Bieber, T; Thyssen, J P; Reich, K; Simpson, E L; Katoh, N; Torrelo, A; De Bruin-Weller, M; Thaci, D; Bissonnette, R; Gooderham, M; Weisman, J; Nunes, F; Brinker, D; Issa, M; Holzwarth, K; Gamalo, M; Riedl, E; Janes, J (Wiley-Blackwell, 2021-02)

BACKGROUND: Janus kinase (JAK) inhibition is a new mode of action in atopic dermatitis (AD); clarity about drug class safety considerations in the context of AD is important. Baricitinib, an oral, reversible, selective ...
O-serotype distribution of Escherichia coli bloodstream infection isolates in critically ill patients in The Netherlands

Verboom, D M; Varkila, M R J; Morrow, B; Davies, T; Ibarra de Palacios, P; Poolman, J; Hermans, P W M; Dudley, E G; Roberts, E; Cremer, O L; Bonten, M J M (Elsevier, 2021-03-19)

OBJECTIVES: Invasive infections by extra-intestinal pathogenic Escherichia coli (ExPEC) strains are increasing. We determined O-serogroups of E. coli isolates from ICU patients having bloodstream infections (BSI) and the ...
Conjunctivitis in Dupilumab Clinical Trials for Adolescents with Atopic Dermatitis or Asthma

Bansal, Ashish; Simpson, Eric L; Paller, Amy S; Siegfried, Elaine C; Blauvelt, Andrew; de Bruin-Weller, Marjolein; Corren, Jonathan; Sher, Lawrence; Guttman-Yassky, Emma; Chen, Zhen; Daizadeh, Nadia; Kamal, Mohamed A; Shumel, Brad; Mina-Osorio, Paola; Mannent, Leda; Patel, Naimish; Graham, Neil M H; Khokhar, Faisal A; Ardeleanu, Marius (Adis, 2021-01)

Background: Conjunctivitis is a known comorbidity of atopic dermatitis. Dupilumab clinical trials for moderate-to-severe atopic dermatitis in adults showed a higher conjunctivitis incidence for dupilumab-treated patients ...
Twist activates miR-22 to suppress estrogen receptor alpha in breast cancer

Vesuna, Farhad; Lisok, Ala; van Diest, Paul; Raman, Venu (Springer Netherlands, 2021-06)

TWIST1 (Twist) is a basic helix-loop-helix transcription factor that is overexpressed in many cancers and promotes tumor cell invasion, metastasis, and recurrence. In this study, we demonstrate that Twist upregulates ...
Deep learning-based grading of ductal carcinoma in situ in breast histopathology images

Wetstein, Suzanne C.; Stathonikos, Nikolas; Pluim, Josien P.W.; Heng, Yujing J.; ter Hoeve, Natalie D.; Vreuls, Celien P.H.; van Diest, Paul J.; Veta, Mitko (Elsevier, 2021-04)

Ductal carcinoma in situ (DCIS) is a non-invasive breast cancer that can progress into invasive ductal carcinoma (IDC). Studies suggest DCIS is often overtreated since a considerable part of DCIS lesions may never progress ...
Laboratory safety of dupilumab for up to 3 years in adults with moderate-to-severe atopic dermatitis: results from an open-label extension study

Beck, Lisa A; Thaçi, Diamant; Deleuran, Mette; de Bruin-Weller, Marjolein; Chen, Zhen; Khokhar, Faisal A; Zhang, Meng; Ozturk, Zafer E; Shumel, Brad (Informa Healthcare, 2022-05)

BACKGROUND: Most systemic agents used for moderate-to-severe atopic dermatitis (AD) may lead to adverse events requiring routine laboratory monitoring, increasing patient burden and possibly decreasing treatment adherence. ...

Now showing items 16741-16760 of 40729