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Patient Preferences for Lung Cancer Treatment: A Qualitative Study Protocol Among Advanced Lung Cancer Patients

Durosini, Ilaria; Janssens, Rosanne; Arnou, Reinhard; Veldwijk, Jorien; Smith, Meredith Y; Monzani, Dario; Smith, Ian; Galli, Giulia; Garassino, Marina; Katz, Eva G; Bailo, Luca; Louis, Evelyne; Vandevelde, Marie; Nackaerts, Kristiaan; de Wit, G Ardine; Pravettoni, Gabriella; Huys, Isabelle (Frontiers Media S. A., 2021-02-05)

Introduction: Lung cancer is the deadliest and most prevalent cancer worldwide. Lung cancer treatments have different characteristics and are associated with a range of benefits and side effects for patients. Such differences ...
Blood Flow Velocity Pulsatility and Arterial Diameter Pulsatility Measurements of the Intracranial Arteries Using 4D PC-MRI

van Hespen, Kees M; Kuijf, Hugo J; Hendrikse, Jeroen; Luijten, Peter R; Zwanenburg, Jaco J M (Humana Press, 2022-04)

4D phase contrast magnetic resonance imaging (PC-MRI) allows for the visualization and quantification of the cerebral blood flow. A drawback of software that is used to quantify the cerebral blood flow is that it oftentimes ...
Identifying the critically ill paediatric oncology patient: a study protocol for a prospective observational cohort study for validation of a modified Bedside Paediatric Early Warning System score in hospitalised paediatric oncology patients

Soeteman, Marijn; Kappen, Teus H; van Engelen, Martine; Kilsdonk, Ellen; Koomen, Erik; Nieuwenhuis, Edward E S; Tissing, Wim J E; Fiocco, Marta; van den Heuvel-Eibrink, Marry; Wösten-van Asperen, Roelie M (BMJ Publishing Group, 2021-05-19)

INTRODUCTION: Hospitalised paediatric oncology patients are at risk to develop acute complications. Early identification of clinical deterioration enabling adequate escalation of care remains challenging. Various Paediatric ...
Perioperative hypotension 2021: a contrarian view

Kappen, Teus; Beattie, William Scott (Oxford University Press, 2021-08)
Methodological Priorities for Patient Preferences Research: Stakeholder Input to the PREFER Public-Private Project

Smith, Ian P; DiSantostefano, Rachael L; de Bekker-Grob, Esther W; Levitan, Bennett; Berlin, Conny; Veldwijk, Jorien; de Wit, G Ardine (ADIS INT LTD, 2021-09)
Catheter-based alcohol-mediated renal denervation for the treatment of uncontrolled hypertension: design of two sham-controlled, randomized, blinded trials in the absence (TARGET BP OFF-MED) and presence (TARGET BP I) of antihypertensive medications

Mahfoud, Felix; Weber, Michael; Schmieder, Roland E; Lobo, Melvin D; Blankestijn, Peter J; Persu, Alexandre; Fischell, Tim A; Parise, Helen; Pathak, Atul; Kandzari, David E (Mosby Inc., 2021-09)

BACKGROUND: Arterial hypertension is a common and life-threatening condition and poses a large global health burden. Device-based treatments have been developed as adjunctive or alternative therapy, to be used with or ...
Whole Blood Mycobacterial Growth Assays for Assessing Human Tuberculosis Susceptibility: A Systematic Review and Meta-Analysis

Bok, Jeroen; Hofland, Regina W.; Evans, Carlton A. (Frontiers Media S. A., 2021-05-11)

Background: Whole blood mycobacterial growth assays (WBMGA) quantify mycobacterial growth in fresh blood samples and may have potential for assessing tuberculosis vaccines and identifying individuals at risk of tuberculosis. ...
Understanding overuse of diagnostic imaging for patients with low back pain in the Emergency Department: A qualitative study

Blokzijl, Johan; Dodd, Rachael H.; Copp, Tessa; Sharma, Sweekriti; Tcharkhedian, Elise; Klinner, Christiane; Maher, Chris G.; Traeger, Adrian C. (BMJ Publishing Group, 2021-07)

Background: Overuse of lumbar imaging in the Emergency Department is a well-recognised healthcare challenge. Studies to date have not provided robust evidence that available interventions can reduce overuse. For an ...
Second allogeneic transplants for multiple myeloma: a report from the EBMT Chronic Malignancies Working Party

Hayden, Patrick J; Eikema, Dirk-Jan; de Wreede, Liesbeth C; Koster, Linda; Kröger, Nicolaus; Einsele, Hermann; Minnema, Monique; Dominietto, Alida; Potter, Michael; Passweg, Jacob; Bermúdez, Arancha; Nguyen-Quoc, Stephanie; Platzbecker, Uwe; Tischer, Johanna; Ciceri, Fabio; Veelken, Joan Hendrik; Ljungman, Per; Schaap, Nicolaas; Forcade, Edouard; Carella, Angelo Michele; Gandemer, Virginie; Arcese, William; Bloor, Adrian; Olivieri, Attilio; Vincent, Laure; Beksac, Meral; Schönland, Stefan; Yakoub-Agha, Ibrahim (Springer Nature, 2021-10)

The EBMT Chronic Malignancies Working Party performed a retrospective analysis of 215 patients who underwent a second allo-HCT for myeloma between 1994 and 2017, 159 for relapse and 56 for graft failure. In the relapse ...
Endomyocardial biopsy with co-localization of a lymphoplasmacytic lymphoma and AL amyloidosis

Leguit, Roos J; Vink, Aryan; de Jonge, Nicolaas; Minnema, Monique C; Oerlemans, Marish I F (Elsevier, 2021-07-01)

In about 4% of cases, amyloid light chain (AL) amyloidosis is due to an underlying lymphoplasmacytic lymphoma (LPL) or other monoclonal protein forming low-grade B-cell lymphoma, instead of a plasma cell neoplasm. We report ...
Missense and truncating variants in CHD5 in a dominant neurodevelopmental disorder with intellectual disability, behavioral disturbances, and epilepsy

Undiagnosed Diseases Network (Springer-Verlag, 2021-07)

Located in the critical 1p36 microdeletion region, the chromodomain helicase DNA-binding protein 5 (CHD5) gene encodes a subunit of the nucleosome remodeling and deacetylation (NuRD) complex required for neuronal development. ...
Adult-onset autoinflammation caused by somatic mutations in UBA1: A Dutch case series of patients with VEXAS

van der Made, Caspar I; Potjewijd, Judith; Hoogstins, Annemiek; Willems, Huub P J; Kwakernaak, A J; de Sevaux, Ruud G L; van Daele, Paul L A; Simons, Annet; Heijstek, Marloes; Beck, David B; Netea, Mihai G; van Paassen, Pieter; Hak, A E; van der Veken, Lars T; van Gijn, Marielle E; Hoischen, Alexander; van der Veerdonk, Frank L; Leavis, Helen L; Rutgers, Abraham (Mosby Inc., 2022-01)

BACKGROUND: A novel autoinflammatory syndrome was recently described in male patients who harbored somatic mutations in the X-chromosomal UBA1 gene. These patients were characterized by adult-onset, treatment-refractory ...
IMPACT OF HORMONAL BIOMARKERS ON RESPONSE TO HORMONAL THERAPY IN ADVANCED AND RECURRENT ENDOMETRIAL CANCER

VAN Weelden, Willem Jan; Lalisang, Roy I; Bulten, Johan; Lindemann, Kristina; VAN Beekhuizen, Heleen J; Trum, Hans; Boll, Dorry; Werner, Henrica M J; VAN Lonkhuijzen, Luc R C W; Yigit, Refika; Forsse, David; Witteveen, Petronella O; Galaal, Khadra; VAN Ginkel, Alexandra; Bignotti, Eliana; Weinberger, Vit; Sweegers, Sanne; Kroep, Judith R; Cabrera, Silvia; Snijders, Marc P L M; Inda, Márcia A; Eriksson, Ane Gerda Z; Krakstad, Camilla; Romano, Andrea; VAN DE Stolpe, Anja; Pijnenborg, Johanna M A (Mosby Inc., 2021-10)

BACKGROUND: Approximately 20% of women with endometrial cancer have advanced-stage disease or suffer from a recurrence. For these women, prognosis is poor, and palliative treatment options include hormonal therapy and ...
High-frequency oscillations recorded with surface EEG in neonates with seizures

Noorlag, Lotte; van 't Klooster, Maryse A.; van Huffelen, Alexander C.; van Klink, Nicole E.C.; Benders, Manon J.N.L.; de Vries, Linda S.; Leijten, Frans S.S.; Jansen, Floor E.; Braun, Kees P.J.; Zijlmans, Maeike (Elsevier Ireland Ltd, 2021-07)

Objective: Neonatal seizures are often the first symptom of perinatal brain injury. High-frequency oscillations (HFOs) are promising new biomarkers for epileptogenic tissue and can be found in intracranial and surface EEG. ...
Pathology of intraductal papillary mucinous neoplasms

Assarzadegan, Naziheh; Thompson, Elizabeth; Salimian, Kevan; Gaida, Matthias M; Brosens, Lodewijk A A; Wood, Laura; Ali, Syed Z; Hruban, Ralph H (Springer-Verlag, 2021-12)

BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) represent a unique opportunity to treat and prevent a curable neoplasm before it has the chance to progress to incurable cancer. This prospect, however, has to ...
The role of altered glycosylation in human nucleus pulposus cells in inflammation and degeneration

Joyce, K; Mohd Isa, I L; Krouwels, A; Creemers, L; Devitt, A; Pandit, A (Forum Multimedia Publishing LLC, 2021-03-28)

Intervertebral disc (IVD) degeneration causes low-back pain through disc compression, prolapse and herniation. Inflammation of the IVD and subsequent degeneration produce altered glycosylation profiles in several animal ...
Intra-Articular Slow-Release Triamcinolone Acetonide from Polyesteramide Microspheres as a Treatment for Osteoarthritis

Tellegen, Anna; Beukers, Martijn; Rudnik-Jansen, Imke; van Klaveren, Nicolien; How, Kan Loi; Woike, Nina; Mihov, George; Thies, Jens; Teske, Erik; Creemers, Laura; Tryfonidou, Marianna; Meij, Björn (Multidisciplinary Digital Publishing Institute, 2021-03-11)

Osteoarthritis (OA) is a common cause of pain and disability. Local corticosteroid injections are effective in treating OA pain and inflammation but are short-acting. Prolonged intra-articular (IA) corticosteroid exposure ...
Nanoghosts: Mesenchymal Stem cells derived nanoparticles as a unique approach for cartilage regeneration

D'Atri, D.; Zerrillo, L.; Garcia, J.; Oieni, J.; Lupu-Haber, Y.; Schomann, T.; Chan, A.; Cruz, L. J.; Creemers, L. B.; Machluf, Marcelle (Elsevier, 2021-09-10)

Osteoarthritis (OA) is a chronic degenerative disease, which affects the joints and is characterized by inflammation, cartilage loss and bone changes. Nowadays, there are no treatments for OA, and current therapies are ...
Tinnitus treatment by vagus nerve stimulation: A systematic review

Stegeman, I; Velde, H M; Robe, P A J T; Stokroos, R J; Smit, A L (Public Library of Science, 2021-03-11)

BACKGROUND: Tinnitus is a phantom sensation of sound, which can have a negative impact on quality of life of those affected. No curative treatments are currently known. Neuromodulation by vagus nerve stimulation has emerged ...
Cochlear Implant Fixation Techniques: A Systematic Review of the Literature

Markodimitraki, Laura M; Strijbos, Ruben M; Stegeman, Inge; Thomeer, Hans G X M (Lippincott Williams & Wilkins, 2021-08-01)

OBJECTIVE: Given the lack of consensus on fixation techniques of the cochlear implant, this review aims to create an up-to-date overview of intra- and postoperative complications, focusing on migration of the internal ...

Now showing items 16281-16300 of 40729