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Now showing items 15961-15980 of 40729

Early health economic analysis of 1.5 T MRI-guided radiotherapy for localized prostate cancer: Decision analytic modelling

Hehakaya, Charisma; van der Voort van Zyp, Jochem; Vanneste, Ben; Grutters, Janneke; Grobbee, Diederick; Verkooijen, Lenny; Frederix, GW (Elsevier Ireland Ltd, 2021-08)

Background and purpose 1.5 Tesla magnetic resonance imaging radiotherapy linear accelerator (MR-Linac) is gaining interest for treatment of localized prostate cancer. Clinical evidence is lacking and it therefore remains ...
Point-of-Care Detection of Nonadherence to Antiretroviral Treatment for HIV-1 in Resource-Limited Settings Using Drug Level Testing for Efavirenz, Lopinavir, and Dolutegravir: A Validation and Pharmacokinetic Simulation Study

Hermans, Lucas E.; Nijhuis, Monique; Tempelman, Hugo A.; Houts, Tom; Schuurman, Rob; Burger, David M.; Wensing, Annemarie M.J.; Heine, Rob Ter (Lippincott Williams & Wilkins, 2021-08-01)

BACKGROUND: Virological failure during antiretroviral treatment (ART) may indicate the presence of drug resistance, but may also originate from nonadherence. Qualitative detection of ART components using drug level testing ...
On the generalizability of diffusion MRI signal representations across acquisition parameters, sequences and tissue types: Chronicles of the MEMENTO challenge

De Luca, Alberto; Ianus, Andrada; Leemans, Alexander; Palombo, Marco; Shemesh, Noam; Zhang, Hui; Alexander, Daniel C; Nilsson, Markus; Froeling, Martijn; Biessels, Geert-Jan; Zucchelli, Mauro; Frigo, Matteo; Albay, Enes; Sedlar, Sara; Alimi, Abib; Deslauriers-Gauthier, Samuel; Deriche, Rachid; Fick, Rutger; Afzali, Maryam; Pieciak, Tomasz; Bogusz, Fabian; Aja-Fernández, Santiago; Özarslan, Evren; Jones, Derek K; Chen, Haoze; Jin, Mingwu; Zhang, Zhijie; Wang, Fengxiang; Nath, Vishwesh; Parvathaneni, Prasanna; Morez, Jan; Sijbers, Jan; Jeurissen, Ben; Fadnavis, Shreyas; Endres, Stefan; Rokem, Ariel; Garyfallidis, Eleftherios; Sanchez, Irina; Prchkovska, Vesna; Rodrigues, Paulo; Landman, Bennet A; Schilling, Kurt G (Academic Press Inc., 2021-10-15)

Diffusion MRI (dMRI) has become an invaluable tool to assess the microstructural organization of brain tissue. Depending on the specific acquisition settings, the dMRI signal encodes specific properties of the underlying ...
Neurosurgical resection for locally recurrent brain metastasis

Hulsbergen, Alexander F C; Abunimer, Abdullah M; Ida, Fidelia; Kavouridis, Vasileios K; Cho, Logan D; Tewarie, Ishaan A; Mekary, Rania A; Schucht, Philippe; Phillips, John G; Verhoeff, Joost J C; Broekman, Marike L D; Smith, Timothy R (Oxford University Press, 2021-12-01)

BACKGROUND: In patients with locally recurrent brain metastases (LRBMs), the role of (repeat) craniotomy is controversial. This study aimed to analyze long-term oncological outcomes in this heterogeneous population. METHODS: ...
ENDOSCOPIC SUBMUCOSAL DISSECTION FOR BARRETT'S RELATED NEOPLASIA IN THE NETHERLANDS: RESULTS OF A NATIONWIDE COHORT OF 130 CASES

Verheij, Eva P.; Van Munster, Sanne N.; Nieuwenhuis, Esther; van Tilburg, Laurelle; Offerhaus, Johan; Meijer, Sybren L.; Brosens, Lodewijk A.; Weusten, Bas L.; Alkhalaf, A.; Schenk, B. E.; Schoon, Erik. J.; Curvers, Wouter; Van De Ven, Steffi E.; Nagengast, Wouter B.; Houben, Martin H.; Bergman, Jacques; Koch, Arjun D.; Pouw, Roos E. (Mosby Inc., 2021-06)

Introduction Endoscopic resection (ER) is the standard of care for early neoplasia in Barrett’s esophagus (BE). Generally, (piecemeal) ER is used to remove early neoplasia, yet the use of endoscopic submucosal dissection ...
NOT NEOANTIGEN QUANTITY, BUT NEOANTIGEN QUALITY, COPY NUMBER ALTERATIONS AND FUSIONS ARE ASSOCIATED WITH SURVIVAL IN PANCREATIC CANCER

Levink, Iris J.; Brosens, Lodewijk A.; Aberle, Merel R.; Rensen, Sander S.; Cahen, D. L.; Damink, Steven W. Olde; Bruno, Marco J.; Buschow, Sonja I.; Fuhler, Gwenny; Peppelenbosch, Maikel (W.B. Saunders, 2021-05)

Introduction: Immunotherapy has not been effective for pancreatic ductal adenocarcinoma (PDAC). However, factors underlying antitumor immunity in PDAC are poorly understood. We hypothesized that, for PDAC, not the quantity ...
SURVEILLANCE AND ENDOSCOPIC RECOGNITION OF GASTRIC INTESTINAL METAPLASIA AND ATROPHIC GASTRITIS: A RETROSPECTIVE COHORT STUDY IN TWO ACADEMIC CENTERS

Honing, Judith; Dieninyte, Egle; O'Donovan, Maria; Brosens, Lodewijk A.; Fitzgerald, Rebecca C.; Weusten, Bas L.; Di Pietro, Massimiliano (Mosby Inc., 2021-06)

Introduction Gastric cancer is the third leading cause of cancer-related deaths in the world. Gastric intestinal metaplasia (GIM) and atrophic gastritis (GA) are known precursors to gastric adenocarcinoma. European Society ...
Genetic Characterization of Hepatoid Tumors from Different Organs: Context Matters

Luchini, Claudio; Lawlor, Rita; Sciammarella, Concetta; Mafficini, Andrea; Paolino, Gaetano; Mattiolo, Paola; Brosens, Lodewijk; Adsay, N. Volkan; Cheng, Liang; Scarpa, Aldo (Elsevier, 2021-03)

Background: Hepatoid tumors (HT) are a rare group of cancers resembling morphologically hepatocellular carcinoma, which arise in different organs other than liver. A comprehensive molecular profile of this group of neoplasms ...
Emotion regulation in response to daily negative and positive events in youth: The role of event intensity and psychopathology

Hiekkaranta, Anu P; Kirtley, Olivia J; Lafit, Ginette; Decoster, Jeroen; Derom, Catherine; de Hert, Marc; Gülöksüz, Sinan; Jacobs, Nele; Menne-Lothmann, Claudia; Rutten, Bart P F; Thiery, Evert; van Os, Jim; van Winkel, Ruud; Wichers, Marieke; Myin-Germeys, Inez (Elsevier Limited, 2021-09)

Environmental and individual contextual factors profoundly influence how people regulate their emotions. The current article addresses the role of event intensity and psychopathology (an admixture of depression, anxiety, ...
What makes the psychosis 'clinical high risk' state risky: psychosis itself or the co-presence of a non-psychotic disorder?

Hasmi, Laila; Pries, Lotta-Katrin; Ten Have, Margreet; de Graaf, Ron; van Dorsselaer, Saskia; Bak, Maarten; Kenis, Gunter; Richards, Alexander; Lin, Bochao D; O'Donovan, Michael C; Luykx, Jurjen J; Rutten, Bart P F; Guloksuz, Sinan; van Os, Jim (Cambridge University Press, 2021-07-06)

AIMS: Although attenuated psychotic symptoms in the psychosis clinical high-risk state (CHR-P) almost always occur in the context of a non-psychotic disorder (NPD), NPD is considered an undesired 'comorbidity' epiphenomenon ...
The genetics of drug-related movement disorders (DRMD), reply to comment: Antipsychotic-induced catatonia and neuroleptic malignant syndrome: The dark side of the moon

van der Burg, Nadine C; Al Hadithy, Asmar F Y; van Harten, Peter N; van Os, Jim; Bakker, P Roberto (Springer Nature, 2021-11)
Individualized prediction of three- and six-year outcomes of psychosis in a longitudinal multicenter study: a machine learning approach

GROUP Investigators (Nature Publishing Group, 2021-07-02)

Schizophrenia and related disorders have heterogeneous outcomes. Individualized prediction of long-term outcomes may be helpful in improving treatment decisions. Utilizing extensive baseline data of 523 patients with a ...
The relation between psychological distress and medication adherence in lung transplant candidates and recipients: A cross-sectional study

Wessels-Bakker, Marion J.; van de Graaf, Eduard A.; Kwakkel-van Erp, Johanna M.; Heijerman, Harry G.; Cahn, Wiepke; Schappin, Renske (Wiley-Blackwell, 2022-03)

Aims and objectives: To explore the prevalence of psychological distress such as anxiety, depression and post-traumatic stress disorder and its associations with medication adherence in lung transplant patients. Background: ...
Donor-Derived Testicular Germ Cell Cancer in a Heart Transplant Recipient

Oerlemans, Marish I.F.J.; Groenewegen, Gerard; Vink, Aryan; van Laake, Linda W.; van der Kaaij, Niels P.; de Jonge, Nicolaas (Elsevier, 2021-06)
Cardiac regenerative capacity: an evolutionary afterthought?

Nguyen, Phong D.; de Bakker, Dennis E.M.; Bakkers, Jeroen (Springer Science and Business Media Deutschland GmbH, 2021-06)

Cardiac regeneration is the outcome of the highly regulated interplay of multiple processes, including the inflammatory response, cardiomyocyte dedifferentiation and proliferation, neovascularization and extracellular ...
In Vivo Induction of Regulatory T Cells Via CTLA-4 Signaling Peptide to Control Autoimmune Encephalomyelitis and Prevent Disease Relapse

Kim, Gil Ran; Kim, Won Ju; Lim, Sangho; Lee, Hong Gyun; Koo, Ja Hyun; Nam, Kyung Ho; Kim, Sung Min; Park, Sung Dong; Choi, Je Min (Wiley-VCH Verlag, 2021-07-21)

Regulatory T cells play a key role in immune tolerance to self-antigens, thereby preventing autoimmune diseases. However, no drugs targeting Treg cells have been approved for clinical trials yet. Here, a chimeric peptide ...
Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer

Lõhmussaar, Kadi; Oka, Rurika; Espejo Valle-Inclan, Jose; Smits, Milou H.H.; Wardak, Hila; Korving, Jeroen; Begthel, Harry; Proost, Natalie; van de Ven, Marieke; Kranenburg, Onno W.; Jonges, Trudy G.N.; Zweemer, Ronald P.; Veersema, Sebastiaan; van Boxtel, Ruben; Clevers, Hans (Cell Press, 2021-08-05)

Cervical cancer is a common gynecological malignancy often caused by high-risk human papillomavirus. There is a paucity of human-derived culture systems to study the cervical epithelium and the cancers derived thereof. ...
Primary Hypogammaglobulinaemia with Inflammatory Bowel Disease-Like Features: An ECCO CONFER Multicentre Case Series

Albshesh, Ahmad; Eder, Piotr; Ribaldone, Davide Giuseppe; Oldenburg, Bas; de Boer, Nanne K; Mantzaris, Gerassimos J; Savarino, Edoardo Vincenzo; Dragoni, Gabriele; Weisshof, Roni; Truyens, Marie; Festa, Stefano; Maillard, Michel H; Capirchio, Lena; Filip, Rafal; Theodoraki, Eirini; Kopylov, Uri (Elsevier, 2022-01-28)

BACKGROUND: Hypogammaglobulinaemia is a disorder characterized by low serum immunoglobulin levels and a high prevalence of gastrointestinal manifestations. In some cases, clinical and endoscopic features are indistinguishable ...
Next-Generation HLA Sequence Analysis Uncovers Shared Risk Alleles Between Clinically Distinct Forms of Childhood Uveitis

Wennink, Roos A W; de Boer, Joke H; Hiddingh, Sanne; Haasnoot, Anne-Mieke J W; Kalinina Ayuso, Viera; de Hoop, Talitha; van Setten, Jessica; Spierings, Eric; Kuiper, Jonas J W (Association for Research in Vision and Ophthalmology Inc., 2021-07-01)

PURPOSE. Classical alleles of the human leukocyte antigen (HLA) complex have been linked to specific entities of pediatric noninfectious uveitis, yet genetic predisposition encoded by the HLA super-locus across the patient ...
Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia

Faughnan, Marie E; Mager, Johannes J; Hetts, Steven W; Palda, Valerie A; Lang-Robertson, Kelly; Buscarini, Elisabetta; Deslandres, Erik; Kasthuri, Raj S; Lausman, Andrea; Poetker, David; Ratjen, Felix; Chesnutt, Mark S; Clancy, Marianne; Whitehead, Kevin J; Al-Samkari, Hanny; Chakinala, Murali; Conrad, Miles; Cortes, Daniel; Crocione, Claudia; Darling, Jama; de Gussem, Els; Derksen, Carol; Dupuis-Girod, Sophie; Foy, Patrick; Geisthoff, Urban; Gossage, James R; Hammill, Adrienne; Heimdal, Ketil; Henderson, Katharine; Iyer, Vivek N; Kjeldsen, Anette D; Komiyama, Masaki; Korenblatt, Kevin; McDonald, Jamie; McMahon, Jack; McWilliams, Justin; Meek, Mary E; Mei-Zahav, Meir; Olitsky, Scott; Palmer, Sara; Pantalone, Rose; Piccirillo, Jay F; Plahn, Beth; Porteous, Mary E M; Post, Marco C; Radovanovic, Ivan; Rochon, Paul J; Rodriguez-Lopez, Josanna; Sabba, Carlo; Serra, Marcelo; Shovlin, Claire; Sprecher, Dennis; White, Andrew J; Winship, Ingrid; Zarrabeitia, Roberto (American College of Physicians, 2020-12-15)

DESCRIPTION: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease with an estimated prevalence of 1 in 5000 that is characterized by the presence of vascular malformations (VMs). These result in ...

Now showing items 15961-15980 of 40729