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Now showing items 13301-13320 of 40729

Fasting Intervention for Children With Unilateral Renal Tumors to Reduce Toxicity

Oudmaijer, Christiaan A J; van den Boogaard, Winnie M C; Komninos, Daphne S J; Verwaaijen, Emma J; van Santen, Hanneke M; Lilien, Marc R; Hoeijmakers, Jan H J; Wijnen, Marc H W; van den Heuvel-Eibrink, Marry M; Vermeij, Wilbert P (Frontiers Media S. A., 2022-01-27)

Childhood renal tumors account for around 6% of all childhood cancers and 90% of these cases are Wilms tumor. In Europe, the SIOP-RTSG approach is considered standard of care and has resulted in five-year survival rates ...
Non-communicable disease co-morbidity and associated factors in tuberculosis patients: A cross-sectional study in Gabon

Adegbite, BR; Edoa, JR; Agbo Achimi Abdul, JBP; Epola, M; Mevyann, C; Dejon-Agobé, JC; Zinsou, JF; Honkpehedji, YJ; Mpagama, SG; Alabi, AS; Kremsner, PG; Klipstein-Grobusch, K; Adegnika, AA; Grobusch, MP (Elsevier, 2022-03)

Background: There are only limited data from resource-limited settings available on the prevalence of non-communicable diseases and associated risk factors of tuberculosis patients. This study investigated non-communicable ...
Tumor-related molecular determinants of neurocognitive deficits in patients with diffuse glioma

van Kessel, Emma; Berendsen, Sharon; Baumfalk, Anniek E; Venugopal, Hema; Krijnen, Eva A; Spliet, Wim G M; Van Hecke, Wim; Giuliani, Fabrizio; Seute, Tatjana; Van Zandvoort, Martine J E; Snijders, Tom J; Robe, Pierre A (Oxford University Press, 2022-10-01)

BACKGROUND: Cognitive impairment is a common and debilitating symptom in patients with diffuse glioma, and is the result of multiple factors. We hypothesized that molecular tumor characteristics influence neurocognitive ...
Prospective validation of a new imaging scorecard to assess leptomeningeal metastasis: a joint EORTC BTG and RANO effort

Le Rhun, Emilie; Devos, Patrick; Winklhofer, Sebastian; Lmalen, Hafida; Brandsma, Dieta; Kumthekar, Priya; Castellano, Antonella; Compter, Annette; Dhermain, Frederic; Franceschi, Enrico; Forsyth, Peter; Furtner, Julia; Galldiks, Norbert; Pérez-Larraya, Jaime Gállego; Gempt, Jens; Hattingen, Elke; Hempel, Johann Martin; Lukacova, Slavka; Minniti, Giuseppe; O'Brien, Barbara; Postma, Tjeerd J; Roth, Patrick; Rudà, Roberta; Schaefer, Niklas; Schmidt, Nils O; Snijders, Tom J; Thust, Steffi; van den Bent, Martin; van der Hoorn, Anouk; Vogin, Guillaume; Smits, Marion; Tonn, Joerg C; Jaeckle, Kurt; Preusser, Matthias; Glantz, Michael; Wen, Patrick Y; Bendzsus, Martin; Weller, Michael (Oxford University Press, 2022-10-01)

BACKGROUND: Validation of the 2016 RANO MRI scorecard for leptomeningeal metastasis failed for multiple reasons. Accordingly, this joint EORTC Brain Tumor Group and RANO effort sought to prospectively validate a revised ...
Three Cases of Systemic Sclerosis Within One Family With Different Antibodies and Clinical Features

Spierings, Julia; Ong, Voon H.; Denton, Christopher P. (Journal of Rheumatology, 2022-05-01)

Systemic sclerosis (SSc) is a heterogeneous disorder in which both genetic and environmental factors play a role in the pathogenesis.1 Familial occurrence of SSc is uncommon and accounts for < 2% of cases.2 Familial cases ...
Updating and Integrating Core Outcome Sets for Localised, Locally Advanced, Metastatic, and Nonmetastatic Castration-resistant Prostate Cancer: An Update from the PIONEER Consortium

Beyer, Katharina; Moris, Lisa; Lardas, Michael; Omar, Muhammad Imran; Healey, Jemma; Tripathee, Sheela; Gandaglia, Giorgio; Venderbos, Lionne D F; Vradi, Eleni; van den Broeck, Thomas; Willemse, Peter-Paul; Antunes-Lopes, Tiago; Pacheco-Figueiredo, Luis; Monagas, Serenella; Esperto, Francesco; Flaherty, Stephen; Devecseri, Zsuzsanna; Lam, Thomas B L; Williamson, Paula R; Heer, Rakesh; Smith, Emma J; Asiimwe, Alex; Huber, Johannes; Roobol, Monique J; Zong, Jihong; Mason, Malcolm; Cornford, Philip; Mottet, Nicolas; MacLennan, Sara J; N'Dow, James; Briganti, Alberto; MacLennan, Steven; Van Hemelrijck, Mieke; PIONEER Consortium (Elsevier, 2022-05)

CONTEXT: Harmonisation of outcome reporting and definitions for clinical trials and routine patient records can enable health care systems to provide more efficient outcome-driven and patient-centred interventions. We ...
Patient-reported outcomes during checkpoint inhibition: insight into symptom burden in daily clinical practice

Koldenhof, J J; van der Baan, F H; Verberne, E G; Kamphuis, A M; Verheijden, R J; Tonk, E H; van Lindert, A S; van der Stap, J; Teunissen, S C; Witteveen, P O; Suijkerbuijk, K P (Elsevier, 2022-06)

CONTEXT: While praised for inducing durable anti-tumour responses, immune checkpoint inhibitors (ICI) also cause immune-related adverse events (irAEs) that can vary in severity and affect health-related quality of life ...
Brain retraction injury after elective aneurysm clipping: a retrospective single-center cohort study

Konya, B.; Dankbaar, J. W.; van der Zwan, A. (Springer, 2022-03)

Background: BRI is estimated to occur in 10% of skull-base surgery and 5% of aneurysm surgery. These estimates are based on a few studies with unclear methodology. The purpose of this study is to assess the rate of BRI ...
First experimental exploration of real-time cardiorespiratory motion management for future stereotactic arrhythmia radioablation treatments on the MR-linac

Akdag, Osman; Borman, Pim T S; Woodhead, Peter L; Uijtewaal, Prescilla; Mandija, Stefano; van Asselen, Bram; Verhoeff, Joost J C; Raaymakers, Bas W; Fast, Martin F (IOP Publishing Ltd., 2022-03-21)

Objective.Stereotactic arrhythmia radioablation (STAR) is a novel, non-invasive treatment for refractory ventricular tachycardia (VT). The VT isthmus is subject to both respiratory and cardiac motion. Rapid cardiac motion ...
Creating an optimal observational sleep stage classification system for very and extremely preterm infants

de Groot, E R; Bik, A; Sam, C; Wang, X; Shellhaas, R A; Austin, T; Tataranno, M L; Benders, M J N L; van den Hoogen, A; Dudink, J (Elsevier, 2022-02)

BACKGROUND: Sleep plays a major role in neuronal survival and guiding the fetal brain's development. Preterm infants in the neonatal intensive care unit are exposed to numerous external stimuli that can severely disrupt ...
Towards diagnostic criteria for malignant deep penetrating melanocytic tumors using single nucleotide polymorphism array and next-generation sequencing

MOLecular Evaluation of Melanocytic Ambiguous Tumors (MOLEMAT) investigators (Elsevier, 2022-08)

Cutaneous deep penetrating melanocytic neoplasms frequently simulate melanoma and might occasionally progress to metastatic melanoma. Distinguishing deep penetrating nevi (DPN) and deep penetrating melanocytomas (DPM) from ...
Colonoscopic-Assisted Laparoscopic Wedge Resection for Colonic Lesions: A Prospective Multicenter Cohort Study (LIMERIC-Study)

Leicher, Laura W; Huisman, Jelle F; van Grevenstein, Wilhelmina M U; Didden, Paul; Backes, Yara; Offerhaus, G Johan A; Laclé, Miangela M; Moll, Freek C P; Geesing, Joost M J; Smakman, Niels; Droste, Jochim S Terhaar Sive; Verdaasdonk, Emiel G G; Ter Borg, Frank; Talsma, A Koen; Erkelens, G Willemien; van der Zaag, Edwin S; Schrauwen, Ruud W M; van Wely, Bob J; Schot, Ingrid; Vermaas, Maarten; van Bergeijk, Jeroen D; Sietses, Colin; Hazen, Wouter L; Wasowicz, Dareczka K; Ramsoekh, Dewkoemar; Tuynman, Jurriaan B; Alderlieste, Yasser A; Renger, Rutger-Jan; Oort, Frank A; Bilgen, Ernst Jan Spillenaar; Vleggaar, Frank P; Vasen, Hans F A; Cappel, Wouter H de Vos Tot Nederveen; Moons, Leon M G; van Westreenen, Henderik L (Lippincott Williams & Wilkins, 2022-05-01)

OBJECTIVE: The aim of this study was to evaluate the safety and efficacy of a modified CAL-WR. SUMMARY BACKGROUND DATA: The use of segmental colectomy in patients with endoscopically unresectable colonic lesions results ...
Clomiphene citrate for men with hypogonadism: a systematic review and meta-analysis

Huijben, Manou; Lock, M. Tycho W.T.; de Kemp, Vincent F.; de Kort, Laetitia M.O.; van Breda, H. M.K. (John Wiley & Sons Inc., 2022-03)

Background: Male hypogonadism is a clinical and biochemical androgen insufficiency syndrome, becoming more prevalent with age. Exogenous testosterone is first-choice therapy, with several side effects, including negative ...
What is the clinical meaning of a negative bulbocavernosus reflex in spinal cord injury patients?

Wyndaele, Jean Jacques; Quaghebeur, Jörgen; Wyndaele, Michel (Nature Publishing Group, 2022-02-18)

STUDY DESIGN: This is a retrospective cohort study. OBJECTIVE: To highlight some issues about the clinical meaning of a negative bulbocavernosus reflex (BCR) in spinal cord injury (SCI) patients. SETTINGS: Research group ...
European Society of Cardiology Quality Indicators for Cardiovascular Disease Prevention: developed by the Working Group for Cardiovascular Disease Prevention Quality Indicators in collaboration with the European Association for Preventive Cardiology of the European Society of Cardiology

Aktaa, Suleman; Gencer, Baris; Arbelo, Elena; Davos, Constantinos H; Désormais, Ileana; Hollander, Monika; Abreu, Ana; Ambrosetti, Marco; Bäck, Maria; Carballo, David; Crawford, Carolyn; Deaton, Christi; Dendale, Paul; Eijsvogels, Thijs M H; Galbraith, Mary; Piepoli, Massimo Francesco; Salzwedel, Annett; Smulders, Yvo; Wilhelm, Matthias; Biondi-Zoccai, Giuseppe; Mach, François; Visseren, Frank L J; Gale, Chris P (Oxford University Press, 2022-05-25)

AIMS: To develop a set of quality indicators (QIs) for the evaluation of the care and outcomes for atherosclerotic cardiovascular disease (ASCVD) prevention. METHODS AND RESULTS: The Quality Indicator Committee of the ...
2021 ESC Guidelines on cardiovascular disease prevention in clinical practice

ESC Scientific Document Group (Oxford University Press, 2022-02-19)
2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: Developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies With the special contribution of the European Association of Preventive Cardiology (EAPC)

ESC (Oxford University Press, 2021-09-07)
Distinct Metabolomic Signatures in Preclinical and Obstructive Hypertrophic Cardiomyopathy

Schuldt, Maike; van Driel, Beau; Algül, Sila; Parbhudayal, Rahana Y; Barge-Schaapveld, Daniela Q C M; Güçlü, Ahmet; Jansen, Mark; Michels, Michelle; Baas, Annette F; van de Wiel, Mark A; Nieuwdorp, Max; Levin, Evgeni; Germans, Tjeerd; Jans, Judith J M; van der Velden, Jolanda (Multidisciplinary Digital Publishing Institute (MDPI), 2021-10-29)

Hypertrophic Cardiomyopathy (HCM) is a common inherited heart disease with poor risk prediction due to incomplete penetrance and a lack of clear genotype-phenotype correlations. Advanced imaging techniques have shown altered ...
Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial

COMPASS study group (Elsevier, 2021-05)

Background: Volanesorsen is an antisense oligonucleotide that targets hepatic apolipoprotein C-III synthesis and reduces plasma triglyceride concentration. The aim of this study was to explore the safety and efficacy of ...
Systematic Coronary Risk Evaluation (SCORE): JACC Focus Seminar 4/8

European Society of Cardiology Cardiovascular Risk Collaboration (Elsevier, 2021-06-22)

Clinical estimation of the combined effect of several risk factors is unreliable and this resulted in the development of a number of risk estimation systems to guide clinical practice. Here, after defining general principles ...

Now showing items 13301-13320 of 40729