Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

  • Analysing the protection from respiratory tract infections and allergic diseases early in life by human milk components: the PRIMA birth cohort 
    PRIMA Initiative Group (BioMed Central, 2022-02-14)
    BACKGROUND: Many studies support the protective effect of breastfeeding on respiratory tract infections. Although infant formulas have been developed to provide adequate nutritional solutions, many components in human milk ...
  • Proposal for a 6-step approach for differential diagnosis of neonatal erythroderma 
    Cuperus, E.; Bygum, A.; Boeckmann, L.; Bodemer, C.; Bolling, M. C.; Caproni, M.; Diociaiuti, A.; Emmert, S.; Fischer, J.; Gostynski, A.; Guez, S.; van Gijn, M. E.; Hannulla-Jouppi, K.; Has, C.; Hernández-Martín, A.; Martinez, A. E.; Mazereeuw-Hautier, J.; Medvecz, M.; Neri, I.; Sigurdsson, V.; Suessmuth, K.; Traupe, H.; Oji, V.; Pasmans, S. G.M.A. (Wiley-Blackwell, 2022-07)
    The broad differential diagnosis of neonatal erythroderma often poses a diagnostic challenge. Mortality of neonatal erythroderma is high due to complications of the erythroderma itself and the occasionally severe and ...
  • Microglial transcriptomics meets genetics: new disease leads 
    Hol, Elly M; Pasterkamp, R Jeroen (Nature Research, 2022-04)
  • The neurovascular unit in leukodystrophies: towards solving the puzzle 
    Zarekiani, Parand; Nogueira Pinto, Henrique; Hol, Elly M; Bugiani, Marianna; de Vries, Helga E (BioMed Central Ltd., 2022-02-28)
    The neurovascular unit (NVU) is a highly organized multicellular system localized in the brain, formed by neuronal, glial (astrocytes, oligodendrocytes, and microglia) and vascular (endothelial cells and pericytes) cells. ...
  • Development of a clinical prediction model for perinatal deaths in low resource settings 
    Housseine, Natasha; Rijken, Marcus J; Weller, Katinka; Nassor, Nassra Haroub; Gbenga, Kayode; Dodd, Caitlin; Debray, Thomas; Meguid, Tarek; Franx, Arie; Grobbee, Diederick E; Browne, Joyce L (Elsevier, 2022-02)
    Background: Most pregnancy-related deaths in low and middle income countries occur around the time of birth and are avoidable with timely care. This study aimed to develop a prognostic model to identify women at risk of ...
  • Hematological Ratios Are Associated with Acute Kidney Injury and Mortality in Patients That Present with Suspected Infection at the Emergency Department 
    de Hond, Titus A.P.; Ocak, Gurbey; Groeneweg, Leonie; Oosterheert, Jan Jelrik; Haitjema, Saskia; Khairoun, Meriem; Kaasjager, Karin A.H. (Multidisciplinary Digital Publishing Institute (MDPI), 2022-02-01)
    The early recognition of acute kidney injury (AKI) is essential to improve outcomes and prevent complications such as chronic kidney disease, the need for renal-replacement therapy, and an increased length of hospital stay. ...
  • Physical Activity Is Associated with Improved Overall Survival among Patients with Metastatic Colorectal Cancer 
    Smit, Karel C; Derksen, Jeroen W G; Beets, Geerard L O; Belt, Eric J Th; Berbée, Maaike; Coene, Peter Paul L O; van Cruijsen, Hester; Davidis, Marjan A; Dekker, Jan Willem T; van Dodewaard-de Jong, Joyce M; Haringhuizen, Annebeth W; Helgason, Helgi H; Hendriks, Mathijs P; Hoekstra, Ronald; de Hingh, Ignace H J T; IJzermans, Jan N M; Janssen, Johan J B; Konsten, Joop L M; Los, Maartje; Mekenkamp, Leonie J M; Nieboer, Peter; Peeters, Koen C M J; Peters, Natascha A J B; Pruijt, Hans J F M; Quarles van Ufford-Mannesse, Patricia; Rietbroek, Ron C; Schiphorst, Anandi H W; Schouten van der Velden, Arjan; Schrauwen, Ruud W M; Sie, Mark P S; Sommeijer, Dirkje W; Sonneveld, Dirk J A; Stockmann, Hein B A C; Tent, Marleen; Terheggen, Frederiek; Tjin-A-Ton, Manuel L R; Valkenburg-van Iersel, Liselot; van der Velden, Ankie M T; Vles, Wouter J; van Voorthuizen, Theo; Wegdam, Johannes A; de Wilt, Johannes H W; Koopman, Miriam; May, Anne M; On Behalf Of The Plcrc Study Group (Multidisciplinary Digital Publishing Institute (MDPI), 2022-02-16)
    Regular physical activity (PA) is associated with improved overall survival (OS) in stage I-III colorectal cancer (CRC) patients. This association is less defined in patients with metastatic CRC (mCRC). We therefore conducted ...
  • Toxicity and efficacy of chronomodulated chemotherapy: a systematic review 
    Printezi, Markella I; Kilgallen, Aoife B; Bond, Marinde J G; Štibler, Urška; Putker, Marrit; Teske, Arco J; Cramer, Maarten J; Punt, Cornelis J A; Sluijter, Joost P G; Huitema, Alwin D R; May, Anne M; van Laake, Linda W (Elsevier Limited, 2022-03)
    Timing chemotherapy on the basis of the body's intrinsic circadian clock-ie, chronomodulated chemotherapy-might improve efficacy and reduce treatment toxicity. This systematic review summarises the available clinical ...
  • Analysis of the circRNA and T-UCR populations identifies convergent pathways in mouse and human models of Rett syndrome 
    Siqueira, Edilene; Obiols-Guardia, Aida; Jorge-Torres, Olga C.; Oliveira-Mateos, Cristina; Soler, Marta; Ramesh-Kumar, Deepthi; Setién, Fernando; van Rossum, Daniëlle; Pascual-Alonso, Ainhoa; Xiol, Clara; Ivan, Cristina; Shimizu, Masayoshi; Armstrong, Judith; Calin, George A.; Pasterkamp, R. Jeroen; Esteller, Manel; Guil, Sonia (Nature Publishing Group, 2022-03-08)
    Noncoding RNAs play regulatory roles in physiopathology, but their involvement in neurodevelopmental diseases is poorly understood. Rett syndrome is a severe, progressive neurodevelopmental disorder linked to loss-of-function ...
  • The mouse brain after foot shock in four dimensions: Temporal dynamics at a single-cell resolution 
    Bonapersona, Valeria; Schuler, Heike; Damsteegt, Ruth; Adolfs, Youri; Pasterkamp, R. Jeroen; van den Heuvel, Martijn P.; Joëls, Marian; Sarabdjitsingh, R. Angela (National Academy of Sciences, 2022-02-22)
    Acute stress leads to sequential activation of functional brain networks. A biologically relevant question is exactly which (single) cells belonging to brain networks are changed in activity over time after acute stress ...
  • Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors 
    Donega, Vanessa; van der Geest, Astrid T.; Sluijs, Jacqueline A.; van Dijk, Roland E.; Wang, Chi Chiu; Basak, Onur; Pasterkamp, R. Jeroen; Hol, Elly M. (Nature Publishing Group, 2022-02-24)
    Following the decline of neurogenesis at birth, progenitors of the subventricular zone (SVZ) remain mostly in a quiescent state in the adult human brain. The mechanisms that regulate this quiescent state are still unclear. ...
  • What do X-ray images of the bladder during video urodynamics show us in patients with spinal cord injury? 
    Wyndaele, Jean Jacques; Wyndaele, Michel; Rapidi, Christina-Anastasia; Krassioukov, Andrei (Springer Nature, 2022-05)
    STUDY DESIGN: Retrospective anonymized cohort study. OBJECTIVES: To study X-ray images of video urodynamics (VUD) in patients with spinal cord injury (SCI). SETTING: Single-center study. METHODS: X-ray images during VUD ...
  • Virtual Resection: A New Tool for Preparing for Nephron-Sparing Surgery in Wilms Tumor Patients 
    van der Zee, Jasper M.; Fitski, Matthijs; Simonis, Frank F.J.; van de Ven, Cornelis P.; Klijn, Aart J.; Wijnen, Marc H.W.A.; van der Steeg, Alida F.W. (Multidisciplinary Digital Publishing Institute (MDPI), 2022-02-01)
    Nephron-sparing surgery (NSS) in Wilms tumor (WT) patients is a surgically challenging procedure used in highly selective cases only. Virtual resections can be used for preoperative planning of NSS to estimate the remnant ...
  • Patient-tailored healthcare and tibial nerve neuromodulation in the treatment of patients with overactive bladder symptoms 
    Te Dorsthorst, Manon; Digesu, Alex; van Kerrebroeck, Philip; Elneil, Sohier; van Breda, Jetske; Janssen, Dick; Martens, Frank; van Balken, Michael; Heesakkers, John (John Wiley & Sons Inc., 2022-02)
    PURPOSE: The aim of this study was to demonstrate features predictive of treatment response for patient-tailored overactive bladder (OAB) intervention with an implantable tibial neurostimulator using patient and technical ...
  • Recurrent de novo missense variants across multiple histone H4 genes underlie a neurodevelopmental syndrome 
    Deciphering Developmental Disorders Study (Cell Press, 2022-04-07)
    Chromatin is essentially an array of nucleosomes, each of which consists of the DNA double-stranded fiber wrapped around a histone octamer. This organization supports cellular processes such as DNA replication, DNA ...
  • A Practical Workflow for Organizing Clinical Intraoperative and Long-term iEEG Data in BIDS 
    on behalf of the RESPect group (Humana Press, 2022-07)
    The neuroscience community increasingly uses the Brain Imaging Data Structure (BIDS) to organize data, extending from MRI to electrophysiology data. While automated tools and workflows are developed that help organize MRI ...
  • Efficacy of BCG Vaccination Against Respiratory Tract Infections in Older Adults During the Coronavirus Disease 2019 Pandemic 
    Moorlag, Simone J C F M; Taks, Esther; Ten Doesschate, Thijs; van der Vaart, Thomas W; Janssen, Axel B; Müller, Lisa; Ostermann, Philipp; Dijkstra, Helga; Lemmers, Heidi; Simonetti, Elles; Mazur, Marc; Schaal, Heiner; Ter Heine, Rob; van de Veerdonk, Frank L; Bleeker-Rovers, Chantal P; van Crevel, Reinout; Ten Oever, Jaap; de Jonge, Marien I; Bonten, Marc J; van Werkhoven, Cornelis H; Netea, Mihai G (Oxford University Press, 2022-07-01)
    BACKGROUND: Older age is associated with increased severity and death from respiratory infections, including coronavirus disease 2019 (COVID-19). The tuberculosis BCG vaccine may provide heterologous protection against ...
  • Lowbury Lecture 2021: tales of the unexpected in antibiotic resistance 
    Bonten, Marc (W.B. Saunders Ltd, 2022-05)
    Since the 1990s few new antibiotics have become available; during the same period the appearance and spread of bacteria no longer susceptible to first- and second-line antibiotics has accelerated; indeed some bacterial ...
  • Impact of 7-valent versus 10-valent pneumococcal conjugate vaccines on primary care consultations across various age groups in the Netherlands, 5 years after the switch: A time-series analysis 
    Asogwa, Ogechukwu A.; de Hoog, Marieke L.A.; Bruijning-Verhagen, Patricia C.J.I. (Elsevier, 2022-01-21)
    Background: In 2011, 10-valent pneumococcal conjugate vaccine (PCV10) replaced PCV7 in The Netherlands. We aimed to assess the impact of this switch on non-invasive pneumococcal disease in primary care across various ...
  • Clinical toxicology of exposures to chemicals from clandestine drug laboratories: a literature review 
    Koppen, Arjen; Wijnands-Kleukers, Anja P G; Gresnigt, Femke M J; de Lange, Dylan W (Informa Healthcare, 2022-05-04)
    INTRODUCTION: The synthesis of clandestine drugs is a widespread worldwide phenomenon, with clandestine drug laboratories occurring both in rural and urban areas. There is considerable unfamiliarity among medical professionals ...