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Now showing items 11661-11680 of 40729

Study protocol of the GLOW study: maximising treatment options for recurrent glioblastoma patients by whole genome sequencing-based diagnostics-a prospective multicenter cohort study

van Opijnen, Mark P; Broekman, Marike L D; de Vos, Filip Y F; Cuppen, Edwin; van der Hoeven, Jacobus J M; van Linde, Myra E; Compter, Annette; Beerepoot, Laurens V; van den Bent, Martin J; Vos, Maaike J; Fiebrich, Helle-Brit; Koekkoek, Johan A F; Hoeben, Ann; Kho, Kuan H; Driessen, Chantal M L; Jeltema, Hanne-Rinck; Robe, Pierre A J T; Maas, Sybren L N (BioMed Central, 2022-11-04)

BACKGROUND: Glioblastoma (GBM), the most common glial primary brain tumour, is without exception lethal. Every year approximately 600 patients are diagnosed with this heterogeneous disease in The Netherlands. Despite ...
Cognitive disorders in patients with chronic kidney disease: specificities of clinical assessment

CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) (Oxford University Press, 2022-01)

Neurocognitive disorders are frequent among chronic kidney disease (CKD) patients. Identifying and characterizing cognitive impairment (CI) can help to assess the ability of adherence to CKD risk reduction strategy, identify ...
Shock and kill within the CNS: A promising HIV eradication approach?

Nühn, Marieke M.; Gumbs, Stephanie B.H.; Buchholtz, Ninée V.E.J.; Jannink, Lisanne M.; Gharu, Lavina; de Witte, Lot D.; Wensing, Annemarie M.J.; Lewin, Sharon R.; Nijhuis, Monique; Symons, Jori (Oxford University Press, 2022-11)

The most studied HIV eradication approach is the “shock and kill” strategy, which aims to reactivate the latent reservoir by latency reversing agents (LRAs) and allowing elimination of these cells by immune-mediated clearance ...
Assessing optimal frequency for image acquisition in computer vision systems developed to monitor feeding behavior of group-housed Holstein heifers

Bresolin, T; Ferreira, R; Reyes, F; Van Os, J; Dórea, J R R (Elsevier, 2023-01)

Computer vision systems have emerged as a potential tool to monitor the behavior of livestock animals. Such high-throughput systems can generate massive redundant data sets for training and inference, which can lead to ...
Pharmacological protection of the thyroid gland against radiation damage from radioactive iodine labeled compounds in children: a systematic review

de Lijster, Bas; de Kanter, Clara T.M.M.; de Keizer, Bart; Tytgat, Godelieve A.M.; Vulsma, Thomas; Offringa, Martin; van Santen, Hanneke M. (Springer Verlag Italia, 2023-02)

Purpose: There is currently no consensus on which protective strategy is most effective to prevent I-131 uptake in the thyroid during medical interventions in children. We aimed to collect the best available evidence to ...
Treatment of relapsed and refractory Waldenstrom Macroglobulinemia

Amaador, Karima; Kersten, Marie J; Minnema, Monique C; Vos, Josephine M I (2023-01)

Waldenström's Macroglobulinemia (WM) is a rare type of indolent non-Hodgkin lymphoma (NHL) that remains incurable. Several effective agents such as monoclonal antibodies (in combination with chemotherapy), Bruton's tyrosine ...
Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids

Rodenburg, Lisa W.; Delpiano, Livia; Railean, Violeta; Centeio, Raquel; Pinto, Madalena C.; Smits, Shannon M.A.; van der Windt, Isabelle S.; van Hugten, Casper F.J.; van Beuningen, Sam F.B.; Rodenburg, Remco N.P.; van der Ent, Cornelis K.; Amaral, Margarida D.; Kunzelmann, Karl; Gray, Michael A.; Beekman, Jeffrey M.; Amatngalim, Gimano D. (Multidisciplinary Digital Publishing Institute (MDPI), 2022-10-21)

Individuals with cystic fibrosis (CF) suffer from severe respiratory disease due to a genetic defect in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which impairs airway epithelial ion and fluid ...
Contrast-enhanced Mammography: Moving Ahead with Perfusion Imaging

Mann, Ritse M.; Veldhuis, Wouter B. (Radiological Society of North America Inc., 2022-10-01)
Imaging standardisation in metastatic colorectal cancer: A joint EORTC-ESOI-ESGAR expert consensus recommendation

the European Organisation for Research and Treatment of Cancer (EORTC) Imaging Group; the European Organisation for Research and Treatment of Cancer (EORTC) Gastrointestinal Tract Cancer Group; the European Society of Oncologic Imaging (ESOI) and the European Society of Gastrointestinal and Abdominal Radiology (ESGAR) (Elsevier Limited, 2022-11)

Background: Treatment monitoring in metastatic colorectal cancer (mCRC) relies on imaging to evaluate the tumour burden. Response Evaluation Criteria in Solid Tumors provide a framework on reporting and interpretation of ...
Qualitative interviews results from heart failure survey respondents on the interaction between symptoms and burden of self-care work

Austin, Rosalynn C; Schoonhoven, Lisette; Richardson, Alison; Kalra, Paul R; May, Carl R (Wiley-Blackwell, 2023-08)

AIMS AND OBJECTIVES: Following a cross-sectional survey, a sub-sample of participants was interviewed to explore the interaction between symptoms and burden of treatment. BACKGROUND: Burden of treatment considers both the ...
Beyond transformational leadership in nursing: A qualitative study on rebel nurse leadership-as-practice

Kok, Eline de; Weggelaar, Anne M; Reede, Corijna; Schoonhoven, Lisette; Lalleman, Pieterbas (Wiley, 2023-04)

Most nurse leadership studies have concentrated on a classical, heroic, and hierarchical view of leadership. However, critical leadership studies have argued the need for more insight into leadership in daily nursing ...
Barriers and facilitators to reporting medical device-related pressure ulcers: A qualitative exploration of international practice

Crunden, Ewa A; Worsley, Peter R; Coleman, Susanne B; Schoonhoven, Lisette (Elsevier Limited, 2022-11)

BACKGROUND: Pressure ulcers are a complex healthcare issue. Hospital-acquired pressure ulcers are used as proxy measurements for the quality and safety of nursing care. Medical device-related pressure ulcers are mostly ...
CONVINCE in the context of existing evidence on haemodiafiltration

CONVINCE scientific committee (Oxford University Press, 2022-05-25)

Haemodiafiltration (HDF) provides a greater removal of larger solutes and protein-bound compounds than conventional high-flux haemodialysis (HD). There are indications that the patients receiving the highest convection ...
Quality appraisal of clinical guidelines for recurrent urinary tract infections using AGREE II: a systematic review

Pat, Jorik J; Witte, Lambertus P W; Steffens, Martijn G; Vernooij, Robin W M; Marcelissen, Tom A T; Fuentes, Paulina; Garcia-Perdomo, Herney A; Pardo-Hernandez, Hector; Blanker, Marco H (Springer Nature, 2022-05)

INTRODUCTION AND HYPOTHESIS: Recommendations for preventing and diagnosing recurrent urinary tract infection (UTI) tend to vary between clinical practice guidelines (CPGs) because of low-quality scientific evidence, ...
Central venous catheter-related complications in older haemodialysis patients: A multicentre observational cohort study

van Oevelen, Mathijs; Heggen, Boudewijn Dc; Abrahams, Alferso C; Rotmans, Joris I; Snoeijs, Maarten Gj; Vernooij, Robin Wm; van Buren, Marjolijn; Meijvis, Sabine Ca (Wichtig Publishing, 2023-11)

Background: Central venous catheters (CVC) remain a commonly used vascular access option in haemodialysis, despite guidelines advising to preferably use arteriovenous fistulae. Compared to younger patients, the risk-benefit ...
A Reporting Tool for Adapted Guidelines in Health Care: The RIGHT-Ad@pt Checklist

RIGHT-Ad@pt Working Group* (American College of Physicians, 2022-05)

Background: Adaptation of existing guidelines can be an efficient way to develop contextualized recommendations. Transparent reporting of the adaptation approach can support the transparency and usability of the adapted ...
Evaluación de la calidad de guías de práctica clínica para el tratamiento de psoriasis mediante la herramienta AGREE II

Montesinos-Guevara, C; Andrade Miranda, A; Bedoya-Hurtado, E; Escobar Liquitay, C M; Franco, J V A; Simancas-Racines, D; Sami Amer, Y; Vernooij, R W M; Viteri-García, A (Elsevier Espana S.L.U, 2022-03)

BACKGROUND: Clinical practice guidelines (CPGs) are designed to help health professionals provide patients with excellent medical care. The last critical appraisal of CPGs on the treatment of psoriasis evaluated publications ...
Clinical performance, intermediate and long-term outcomes of high-volume hemodiafiltration in patients with kidney failure

Guedes, Murilo; Vernooij, Robin W M; Davenport, Andrew; Kuhlmann, Martin K; Aregger, Fabienne; Pecoits-Filho, Roberto (Wiley-Blackwell, 2022-09)

Hemodiafiltration (HDF), in which both convective and diffusion methods are combined, yields an increased overall solute clearance compared with hemodialysis (HD), specifically for medium and larger molecular weight uremic ...
Serious reporting deficiencies exist in minimal important difference studies: current state and suggestions for improvement

Carrasco-Labra, Alonso; Devji, Tahira; Qasim, Anila; Phillips, Mark; Johnston, Bradley C; Devasenapathy, Niveditha; Zeraatkar, Dena; Bhatt, Meha; Jin, Xuejing; Brignardello-Petersen, Romina; Urquhart, Olivia; Foroutan, Farid; Schandelmaier, Stefan; Pardo-Hernandez, Hector; Vernooij, Robin Wm; Huang, Hsiaomin; Rizwan, Yamna; Siemieniuk, Reed; Lytvyn, Lyubov; Patrick, Donald L; Ebrahim, Shanil; Furukawa, Toshi A; Nesrallah, Gihad; Schunemann, Holger J; Bhandari, Mohit; Thabane, Lehana; Guyatt, Gordon H (Elsevier, 2022-10)

BACKGROUND AND OBJECTIVES: To evaluate reporting of minimal important difference (MID) estimates using anchor-based methods for patient-reported outcome measures (PROMs), and the association with reporting deficiencies on ...
The Frequency of Primary Healthcare Contacts Preceding the Diagnosis of Lower-Extremity Arterial Disease: Do Women Consult General Practice Differently?

Porras, Cindy P; Teraa, Martin; Bots, Michiel L; de Boer, Annemarijn R; Peters, Sanne A E; van Doorn, Sander; Vernooij, Robin W M (Multidisciplinary Digital Publishing Institute (MDPI), 2022-07-01)

Background. Women with lower-extremity arterial disease (LEAD) are often underdiagnosed, present themselves with more advanced disease at diagnosis, and fare worse than men. Objective. To investigate to what extent potential ...

Now showing items 11661-11680 of 40729