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Now showing items 10721-10740 of 40729

Priorities for research on environment, climate and health, a European perspective

on behalf of the HERA (Health and Environment Research Agenda) Consortium (BioMed Central, 2022-03-28)

Climate change, urbanisation, chemical pollution and disruption of ecosystems, including biodiversity loss, affect our health and wellbeing. Research is crucial to be able to respond to the current and future challenges ...
Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking

Petrovic, Dusan; Bodinier, Barbara; Dagnino, Sonia; Whitaker, Matthew; Karimi, Maryam; Campanella, Gianluca; Haugdahl Nøst, Therese; Polidoro, Silvia; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Lund, Eiliv; Dugué, Pierre Antoine; Giles, Graham G.; Severi, Gianluca; Southey, Melissa; Vineis, Paolo; Stringhini, Silvia; Bochud, Murielle; Sandanger, Torkjel M.; Vermeulen, Roel C.H.; Guida, Florence; Chadeau-Hyam, Marc (Springer Netherlands, 2022-06)

Smoking-related epigenetic changes have been linked to lung cancer, but the contribution of epigenetic alterations unrelated to smoking remains unclear. We sought for a sparse set of CpG sites predicting lung cancer and ...
Quantile regression to examine the association of air pollution with subclinical atherosclerosis in an adolescent population

Peralta, Adjani A.; Schwartz, Joel; Gold, Diane R.; Vonk, Judith M.; Vermeulen, Roel; Gehring, Ulrike (Elsevier Limited, 2022-06)

Background: Air pollution has been associated with carotid intima-media thickness test (CIMT), a marker of subclinical atherosclerosis. To our knowledge, this is the first study to report an association between ambient air ...
Diagnostic prediction models for CT-confirmed and bacterial rhinosinusitis in primary care: individual participant data meta-analysis

Takada, Toshihiko; Hoogland, Jeroen; Hansen, Jens G; Lindbaek, Morten; Autio, Timo; Alho, Olli-Pekka; Ebell, Mark H; Reitsma, Johannes B; Venekamp, Roderick P (Royal College of General Practitioners, 2022-08)

BACKGROUND: Antibiotics are overused in patients with acute rhinosinusitis (ARS) as it is difficult to identify those who benefit from antibiotic treatment. AIM: To develop prediction models for computed tomography ...
A Multipollutant Approach to Estimating Causal Effects of Air Pollution Mixtures on Overall Mortality in a Large, Prospective Cohort

Traini, Eugenio; Huss, Anke; Portengen, Lützen; Rookus, Matti; Verschuren, W. M.Monique; Vermeulen, Roel C.H.; Bellavia, Andrea (Lippincott Williams & Wilkins, 2022-07-01)

Background: Several studies have confirmed associations between air pollution and overall mortality, but it is unclear to what extent these associations reflect causal relationships. Moreover, few studies to our knowledge ...
Ambient ultrafine particles and asthma onset until age 20: The PIAMA birth cohort

Yu, Zhebin; Koppelman, Gerard H.; Boer, Jolanda M.A.; Hoek, Gerard; Kerckhoffs, Jules; Vonk, Judith M.; Vermeulen, Roel; Gehring, Ulrike (Academic Press Inc., 2022-11)

Rationale: Evidence regarding the role of long-term exposure to ultrafine particles (<0.1 μm, UFP) in asthma onset is scarce. Objectives: We examined the association between exposure to UFP and asthma development in the ...
Europe-wide air pollution modeling from 2000 to 2019 using geographically weighted regression

Shen, Youchen; de Hoogh, Kees; Schmitz, Oliver; Clinton, Nicholas; Tuxen-Bettman, Karin; Brandt, Jørgen; Christensen, Jesper H.; Frohn, Lise M.; Geels, Camilla; Karssenberg, Derek; Vermeulen, Roel; Hoek, Gerard (Elsevier Limited, 2022-10)

Previous European land-use regression (LUR) models assumed fixed linear relationships between air pollution concentrations and predictors such as traffic and land use. We evaluated whether including spatially-varying ...
Impact of long-term exposure to PM2.5 on peripheral blood gene expression pathways involved in cell signaling and immune response

Vlaanderen, Jelle; Vermeulen, Roel; Whitaker, Matthew; Chadeau-Hyam, Marc; Hottenga, Jouke Jan; de Geus, Eco; Willemsen, Gonneke; Penninx, Brenda W.J.H.; Jansen, Rick; Boomsma, Dorret I. (Elsevier Limited, 2022-10)

Background: Exposure to ambient air pollution, even at low levels, is a major environmental health risk. The peripheral blood transcriptome provides a potential avenue for the elucidation of ambient air pollution related ...
Long term exposure to air pollution and kidney parenchyma cancer – Effects of low-level air pollution: a Study in Europe (ELAPSE)

Hvidtfeldt, Ulla Arthur; Taj, Tahir; Chen, Jie; Rodopoulou, Sophia; Strak, Maciej; de Hoogh, Kees; Andersen, Zorana J.; Bellander, Tom; Brandt, Jørgen; Fecht, Daniela; Forastiere, Francesco; Gulliver, John; Hertel, Ole; Hoffmann, Barbara; Jørgensen, Jeanette T.; Katsouyanni, Klea; Ketzel, Matthias; Lager, Anton; Leander, Karin; Ljungman, Petter; Magnusson, Patrik K.E.; Nagel, Gabriele; Pershagen, Göran; Rizzuto, Debora; Samoli, Evangelia; So, Rina; Stafoggia, Massimo; Tjønneland, Anne; Vermeulen, Roel; Weinmayr, Gudrun; Wolf, Kathrin; Zhang, Jiawei; Zitt, Emanuel; Brunekreef, Bert; Hoek, Gerard; Raaschou-Nielsen, Ole (Academic Press Inc., 2022-12)

BACKGROUND: Particulate matter (PM) is classified as a group 1 human carcinogen. Previous experimental studies suggest that particles in diesel exhaust induce oxidative stress, inflammation and DNA damage in kidney cells, ...
A Knowledge Transfer Approach to Map Long-Term Concentrations of Hyperlocal Air Pollution from Short-Term Mobile Measurements

Yuan, Zhendong; Kerckhoffs, Jules; Hoek, Gerard; Vermeulen, Roel (American Chemical Society, 2022-09-19)

Mobile measurements are increasingly used to develop spatially explicit (hyperlocal) air quality maps using land-use regression (LUR) models. The prevailing design of mobile monitoring campaigns results in the collection ...
Risk evaluation of cognitive impairment in patients with heart failure: A call for action

Heart-Brain Connection Consortium (Elsevier, 2022-12)

BACKGROUND: Cognitive impairment (CI) is common in patients with heart failure (HF) and impacts treatment adherence and other aspects of patient life in HF. Recognition of CI in patients with HF is therefore important. We ...
Associations between the urban exposome and type 2 diabetes: Results from penalised regression by least absolute shrinkage and selection operator and random forest models

Ohanyan, Haykanush; Portengen, Lützen; Kaplani, Oriana; Huss, Anke; Hoek, Gerard; Beulens, Joline W.J.; Lakerveld, Jeroen; Vermeulen, Roel (Elsevier Limited, 2022-12)

Background: Type 2 diabetes (T2D) is thought to be influenced by environmental stressors such as air pollution and noise. Although environmental factors are interrelated, studies considering the exposome are lacking. We ...
Hyperlocal variation of nitrogen dioxide, black carbon, and ultrafine particles measured with Google Street View cars in Amsterdam and Copenhagen

Kerckhoffs, Jules; Khan, Jibran; Hoek, Gerard; Yuan, Zhendong; Hertel, Ole; Ketzel, Matthias; Jensen, Steen Solvang; Al Hasan, Fares; Meliefste, Kees; Vermeulen, Roel (Elsevier Limited, 2022-12)

Hyperlocal air quality maps are becoming increasingly common, as they provide useful insights into the spatial variation and sources of air pollutants. In this study, we produced several high-resolution concentration maps ...
De verhulde risico’s van screening

van der Graaf, Yolanda (Bohn Stafleu van Loghum, 2022-06-13)

With screening the natural course of disease should be altered to reduce mortality from that disease. Screening offers very little benefit but has many disadvantages like false-positives, overdiagnosis and psychological ...
Invited Perspective: Inroads to Biology-Informed Exposomics

Vermeulen, Roel (Public Health Services, US Dept of Health and Human Services, 2022)
Minimal reporting improvement after peer review in reports of COVID-19 prediction models: systematic review

Hudda, Mohammed T; Archer, Lucinda; van Smeden, Maarten; Moons, Karel G M; Collins, Gary S; Steyerberg, Ewout W; Wahlich, Charlotte; Reitsma, Johannes B; Riley, Richard D; Van Calster, Ben; Wynants, Laure (Elsevier, 2023-02)

OBJECTIVES: To assess improvement in the completeness of reporting coronavirus (COVID-19) prediction models after the peer review process. STUDY DESIGN AND SETTING: Studies included in a living systematic review of COVID-19 ...
The experience of European hospital-based health care workers on following infection prevention and control procedures and their wellbeing during the first wave of the COVID-19 pandemic

van Hout, Denise; Hutchinson, Paul; Wanat, Marta; Pilbeam, Caitlin; Goossens, Herman; Anthierens, Sibyl; Tonkin-Crine, Sarah; Gobat, Nina (Public Library of Science, 2022-02-07)

Background Working under pandemic conditions exposes health care workers (HCWs) to infection risk and psychological strain. A better understanding of HCWs’ experiences of following local infection prevention and control ...
Improving survival prediction of oesophageal cancer patients treated with external beam radiotherapy for dysphagia

Jeene, Paul M.; Kuijper, Steven C.; van den Boorn, Héctor G.; El Sharouni, Sherif Y.; Braam, Pètra M.; Oppedijk, Vera; Verhoeven, Rob H.A.; Hulshof, Maarten C.C.M.; van Laarhoven, Hanneke W.M. (Informa Healthcare, 2022-07)

Introduction: The recent POLDER trial investigated the effects of external beam radiotherapy (EBRT) on dysphagia caused by incurable oesophageal cancer. An estimated life expectancy of minimally three months was required ...
The atonic stomach: a dangerous condition prior to scoliosis surgery

van Urk, P. R.; Bollen, C. W.; Lequin, M. H.; Kruyt, M. C. (Elsevier, 2022-07)

A dilated atonic stomach as part of neuromuscular or syndromic disorders can have devastating results after scoliosis surgery. Patients can be asymptomatic preoperatively and non-clinical signs can be easily overlooked. ...
2-[18F]-FDG PET for imaging brain involvement in patients with long COVID: perspective of the EANM Neuroimaging Committee

Verger, Antoine; Barthel, Henryk; Tolboom, Nelleke; Fraioli, Francesco; Cecchin, Diego; Albert, Nathalie L.; van Berckel, Bart; Boellaard, Ronald; Brendel, Matthias; Ekmekcioglu, Ozgul; Semah, Franck; Traub-Weidinger, Tatjana; van de Weehaeghe, Donatienne; Morbelli, Silvia; Guedj, Eric (Springer-Verlag, 2022-09)

Now showing items 10721-10740 of 40729