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Asking informed consent may lead to significant participation bias and suboptimal cardiovascular risk management in learning healthcare systems

Haitjema, Saskia; UCC CVRM study group (BioMed Central, 2023-12)

BACKGROUND: The Utrecht Cardiovascular Cohort - CardioVascular Risk Management (UCC-CVRM) was set up as a learning healthcare system (LHS), aiming at guideline based cardiovascular risk factor measurement in all patients ...
Bronchoalveolar lavage characteristics correlate with HLA tag SNPs in patients with Löfgren’s syndrome and other sarcoidosis

Karakaya, B.; Schimmelpennink, M. C.; Kocourkova, L.; van der Vis, J. J.; Meek, B.; Grutters, J. C.; Petrek, M.; van Moorsel, C. H.M. (Wiley-Blackwell, 2019-05)

Genetic susceptibility for sarcoidosis and Löfgren’s syndrome (LS) has been associated with prognosis. Human leukocyte antigen (HLA)-DRB1*03 is over-represented in LS, and is associated with a good prognosis, whereas ...
First patient-centred set of outcomes for pulmonary sarcoidosis: A multicentre initiative

Kampstra, Nynke A.; Grutters, Jan C.; Van Beek, Frouke T.; Culver, Daniel A.; Baughman, Robert P.; Renzoni, Elisabetta A.; Wuyts, Wim; Kouranos, Vaslis; Wijsenbeek, Marlies S.; Biesma, Douwe H.; Van Der Wees, Philip J.; Van Der Nat, Paul B. (BMJ Publishing Group, 2019-02-01)

Introduction Routine and international comparison of clinical outcomes enabling identification of best practices for patients with pulmonary sarcoidosis is lacking. The aim of this study was to develop a standard set of ...
Background rates of 41 adverse events of special interest for COVID-19 vaccines in 10 European healthcare databases - an ACCESS cohort study

Willame, C.; Dodd, C.; Durán, C. E.; Elbers, R.J.H.J.; Gini, R.; Bartolini, C.; Paoletti, O.; Wang, L.; Ehrenstein, V.; Kahlert, J.; Haug, U.; Schink, T.; Diez-Domingo, J.; Mira-Iglesias, A.; Carreras, J. J.; Vergara-Hernández, C.; Giaquinto, C.; Barbieri, E.; Stona, L.; Huerta, C.; Martín-Pérez, M.; García-Poza, P.; de Burgos, A.; Martínez-González, M.; Bryant, V.; Villalobos, F.; Pallejà-Millán, M.; Aragón, M.; Souverein, P.; Thurin, N. H.; Weibel, D.; Klungel, O. H.; Sturkenboom, M. C.J.M. (Elsevier, 2023-01-04)

Background: In May 2020, the ACCESS (The vACCine covid-19 monitoring readinESS) project was launched to prepare real-world monitoring of COVID-19 vaccines. Within this project, this study aimed to generate background ...
Quantifying the RSV immunity debt following COVID-19: a public health matter

Billard, Marie Noëlle; Bont, Louis J. (Elsevier Limited, 2023-01)
Cost-effectiveness of monoclonal antibody and maternal immunization against respiratory syncytial virus (RSV) in infants: Evaluation for six European countries

for Respiratory Syncytial Virus Consortium in Europe (RESCEU) investigators (Elsevier, 2023-02-24)

Background: Respiratory syncytial virus (RSV) imposes a substantial burden on pediatric hospital capacity in Europe. Promising prophylactic interventions against RSV including monoclonal antibodies (mAb) and maternal ...
Nirsevimab binding-site conservation in respiratory syncytial virus fusion glycoprotein worldwide between 1956 and 2021: an analysis of observational study sequencing data

Wilkins, Deidre; Langedijk, Annefleur C.; Lebbink, Robert Jan; Morehouse, Christopher; Abram, Michael E.; Ahani, Bahar; Aksyuk, Anastasia A.; Baraldi, Eugenio; Brady, Tyler; Chen, Albert Tian; Chi, Hsin; Choi, Eun Hwa; Cohen, Robert; Danilenko, Daria M.; Gopalakrishnan, Vancheswaran; Greenough, Anne; Heikkinen, Terho; Hosoya, Mitsuaki; Keller, Christian; Kelly, Elizabeth J.; Kragten-Tabatabaie, Leyla; Martinón-Torres, Federico; de Los Santos, Abiel Homero Mascareñas; Nunes, Marta C.; Palomino, María Angélica; Papenburg, Jesse; Pernica, Jeffrey M.; Richmond, Peter; Stein, Renato T.; Tuffy, Kevin M.; Verwey, Charl; Esser, Mark T.; Tabor, David E.; Bont, Louis J.; Clement, Pascale; Gupta, Atul; Hashimoto, Koichi; Komissarova, Kseniya; Laubscher, Matt; Lumertz, Magali; Priante, Elena; Rivero-Calle, Irene; Wadia, Ushma; Yun, Ki Wook (Elsevier Limited, 2023-07-01)

BACKGROUND: Nirsevimab is an extended half-life monoclonal antibody to the respiratory syncytial virus (RSV) fusion protein that has been developed to protect infants for an entire RSV season. Previous studies have shown ...
RSV immunisation: lessons from the COVID-19 pandemic

Billard, Marie Noëlle; Bont, Louis (Elsevier, 2023-03)
Prioritising respiratory syncytial virus prevention in low-income and middle-income countries

RSV Prevention Collaborators (Elsevier, 2023-05-01)
ASO Author Reflections: Towards Consensus on Resectability Assessments and Local Treatment Planning for Patients with Initially Unresectable Colorectal Cancer Liver Metastases

Bond, Marinde J G; Punt, Cornelis J A; Swijnenburg, Rutger-Jan (Springer New York, 2023-04-21)
Frailty and sarcopenia within the earliest national Dutch childhood cancer survivor cohort (DCCSS-LATER): a cross-sectional study

Dutch LATER Study group (Elsevier, 2023-04)

Background: Childhood cancer survivors appear to be at increased risk of frailty and sarcopenia, but evidence on the occurrence of and high-risk groups for these aging phenotypes is scarce, especially in European survivors. ...
Cohort profile of PLUTO: a perioperative biobank focusing on prediction and early diagnosis of postoperative complications

de Mul, Nikki; Verlaan, Diede; Ruurda, Jelle P; van Grevenstein, Wilhelmina M U; Hagendoorn, Jeroen; de Borst, Gert-Jan; Vriens, Menno R; de Bree, Remco; Zweemer, Ronald P; Vogely, Charles; Haitsma Mulier, Jelle L G; Vernooij, Lisette M; Reitsma, Johannes B; de Zoete, Marcel R; Top, Janetta; Kluijtmans, Jan A J; Hoefer, Imo E; Noordzij, Peter; Rettig, Thijs; Marsman, Marije; de Smet, Anne Marie G A; Derde, Lennie; van Waes, Judith; Rijsdijk, Mienke; Schellekens, Willem Jan M; Bonten, Marc J M; Slooter, Arjen J C; Cremer, Olaf L (BMJ Publishing Group, 2023-04-19)

PURPOSE: Although elective surgery is generally safe, some procedures remain associated with an increased risk of complications. Improved preoperative risk stratification and earlier recognition of these complications may ...
Safe shortening of antibiotic treatment duration for complicated Staphylococcus aureus bacteraemia (SAFE trial): Protocol for a randomised, controlled, open-label, non-inferiority trial comparing 4 and 6 weeks of antibiotic treatment

Collaborators SAFE-trial study group (BMJ Publishing Group, 2023-04-21)

Introduction A major knowledge gap in the treatment of complicated Staphylococcus aureus bacteraemia (SAB) is the optimal duration of antibiotic therapy. Safe shortening of antibiotic therapy has the potential to reduce ...
Nintedanib with add-on pirfenidone in idiopathic pulmonary fibrosis: Results of the INJOURNEY trial

INJOURNEY Trial Investigators (American Thoracic Society, 2018-02-01)

Measurements and Main Results: On-treatment gastrointestinal adverse events were reported in 37 of 53 patients (69.8%) treated with nintedanib with add-on pirfenidone and 27 of 51 patients (52.9%) treated with nintedanib ...
Transbronchial Cryobiopsy for Interstitial Lung Disease

Culver, Daniel A.; Grutters, Jan C. (Lippincott Williams & Wilkins, 2018)
The extent of microbiological testing is associated with alteration of antibiotic therapy in adults with community-acquired pneumonia

Wittermans, Esther; Vestjens, Stefan M.T.; Bos, Willem Jan W.; Grutters, Jan C.; van de Garde, Ewoudt M.W.; Vlaminckx, Bart J.M. (Springer-Verlag, 2019-07-01)

The aim of this study was to explore the relationship between the extent of microbiological testing and the frequency of antibiotic alteration in adults hospitalised with community-acquired pneumonia (CAP). We retrospectively ...
Sarcoidosis

Grunewald, Johan; Grutters, Jan C.; Arkema, Elizabeth V.; Saketkoo, Lesley Ann; Moller, David R.; Müller-Quernheim, Joachim (Nature Publishing Group, 2019-12-01)

Sarcoidosis is an inflammatory disorder of unknown cause that is characterized by granuloma formation in affected organs, most often in the lungs. Patients frequently suffer from cough, shortness of breath, chest pain and ...
Systematic review of drug effects in humans and models with surfactant-processing disease

Klay, Dymph; Hoffman, Thijs W.; Harmsze, Ankie M.; Grutters, Jan C.; van Moorsel, Coline H.M. (European Respiratory Society, 2018-09-30)

Fibrotic interstitial pneumonias are a group of rare diseases characterised by distortion of lung interstitium. Patients with mutations in surfactant-processing genes, such as surfactant protein C (SFTPC), surfactant protein ...
Telomerase reverse transcriptase polymorphism rs2736100: A balancing act between cancer and non-cancer disease, a meta-analysis

Snetselaar, Reinier; van Oosterhout, Matthijs F.M.; Grutters, Jan C.; van Moorsel, Coline H.M. (Frontiers Media S. A., 2018-02-01)

The enzyme telomerase reverse transcriptase (TERT) is essential for telomere maintenance. In replicating cells, maintenance of telomere length is important for the preservation of vital genetic information and prevention ...
Added diagnostic value of routinely measured hematology variables in diagnosing immune checkpoint inhibitor mediated toxicity in the emergency department

Niemantsverdriet, Michael S A; Vrijsen, Bram E L; Visser 't Hooft, Therese; Suijkerbuijk, Karijn P M; van Solinge, Wouter W; Ten Berg, Maarten J; Haitjema, Saskia (John Wiley & Sons Inc., 2023-06)

BACKGROUND: Immune checkpoint inhibitors (ICI) show remarkable results in cancer treatment, but at the cost of immune-related adverse events (irAE). irAE can be difficult to differentiate from infections or tumor progression, ...

Now showing items 10081-10100 of 40729