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UMC Repository: Recent submissions

  • Een richtlijn voor inflammatoire blaasaandoeningen? 
    Janssen, Dick A.W.; de Kort, Laetitia M.O. (Springer Science + Business Media, 2023-03)
    The urinary bladder can be affected by different, often rare bladder inflammatory conditions. Most of these conditions will have a profound negative effect on health and quality of life. Treatment of these conditions is ...
  • Tissue clearing and immunostaining to visualize the spatial organization of vasculature and tumor cells in mouse liver 
    Frenkel, Nicola; Poghosyan, Susanna; van Wijnbergen, Jan Willem; van den Bent, Lotte; Wijler, Liza; Verheem, André; Borel Rinkes, Inne; Kranenburg, Onno; Hagendoorn, Jeroen (Frontiers Media S. A., 2023)
    The liver has a complex and hierarchical segmental organization of arteries, portal veins, hepatic veins and lymphatic vessels. In-depth imaging of liver vasculature and malignancies could improve knowledge on tumor ...
  • Possible Value of Faecal Immunochemical Test (FIT) When Added in Symptomatic Patients Referred for Colonoscopy: A Systematic Review 
    Brands, Henrike Jacoba; Van Dijk, Brigit; Brohet, Richard M.; van Westreenen, Henderik L.; de Groot, Jan Willem B.; Moons, Leon M.G.; de Vos tot Nederveen Cappel, Wouter H. (Multidisciplinary Digital Publishing Institute (MDPI), 2023-03-28)
    UNLABELLED: If Colorectal cancer (CRC) is detected and treated early, the survival rate is high. This is one of the reasons that population-based screening programs for the early detection of CRC using the faecal immunochemical ...
  • Sex-specific differences in cytokine signaling pathways in circulating monocytes of cardiovascular disease patients 
    Lu, Chang; Donners, Marjo M P C; Karel, Joël; de Boer, Hetty; van Zonneveld, Anton Jan; den Ruijter, Hester; Jukema, J Wouter; Kraaijeveld, Adriaan; Kuiper, Johan; Pasterkamp, Gerard; Cavill, Rachel; Perales-Patón, Javier; Ferrannini, Ele; Goossens, Pieter; Biessen, Erik A L (Elsevier, 2023-11)
    BACKGROUND AND AIMS: This study aims to identify sex-specific transcriptional differences and signaling pathways in circulating monocytes contributing to cardiovascular disease. METHODS AND RESULTS: We generated sex-biased ...
  • Validity of the Maximal Heart Rate Prediction Models among Runners and Cyclists 
    Kasiak, Przemysław Seweryn; Wiecha, Szczepan; Cieśliński, Igor; Takken, Tim; Lach, Jacek; Lewandowski, Marcin; Barylski, Marcin; Mamcarz, Artur; Śliż, Daniel (Multidisciplinary Digital Publishing Institute (MDPI), 2023-04-14)
    Maximal heart rate (HRmax) is a widely used measure of cardiorespiratory fitness. Prediction of HRmax is an alternative to cardiopulmonary exercise testing (CPET), but its accuracy among endurance athletes (EA) requires ...
  • Long-term functional outcome of secondary shoulder surgery in brachial plexus birth palsy patients a systematic review 
    de Joode, Stijn G C J; Samijo, Steven; Chen, Neal; van Rhijn, Lodewijk W; Schotanus, Martijn G M (British Editorial Society of Bone and Joint Surgery, 2023-04)
    Aims Multiple secondary surgical procedures of the shoulder, such as soft-tissue releases, tendon transfers, and osteotomies, are described in brachial plexus birth palsy (BpBp) patients. the long-term functional outcomes ...
  • Using Intratumor Heterogeneity of Immunohistochemistry Biomarkers to Classify Laryngeal and Hypopharyngeal Tumors Based on Histologic Features 
    Smits, Hilde J G; Ruiter, Lilian N; Breimer, Gerben E; Willems, Stefan M; Philippens, Marielle E P (Elsevier, 2023-08-01)
    Haralick texture features are used to quantify the spatial distribution of signal intensities within an image. In this study, the heterogeneity of proliferation (Ki-67 expression) and immune cells (CD45 expression) within ...
  • Comparison of the relation of the ESC 2021 and ESC 2013 definitions of left bundle branch block with clinical and echocardiographic outcome in cardiac resynchronization therapy 
    Rijks, Jesse; Ghossein, Mohammed A.; Wouters, Philippe C.; Dural, Muhammet; Maass, Alexander H.; Meine, Mathias; Kloosterman, Mariëlle; Luermans, Justin; Prinzen, Frits W.; Vernooy, Kevin; van Stipdonk, Antonius M.W. (Wiley-Blackwell, 2023-04)
    INTRODUCTION: We aimed to investigate the impact of the 2021 European Society of Cardiology (ESC) guideline changes in left bundle branch block (LBBB) definition on cardiac resynchronization therapy (CRT) patient selection ...
  • Preventing Bias in Medical Devices: Identifying Morally Significant Differences 
    de Kanter, Anne Floor J.; van Daal, Manon; de Graeff, Nienke; Jongsma, Karin R. (Routledge, 2023-04-03)
  • The effect of azithromycin on sputum inflammatory markers in bronchiectasis 
    Terpstra, L C; Altenburg, J; Doodeman, H J; Piñeros, Y S Sabogal; Lutter, R; Heijerman, H G M; Boersma, W G (BioMed Central, 2023-12)
    Background: Long term macrolide treatment has been found beneficial in bronchiectasis (BE) -pathogical bronchial dilatation- possibly due to a combined anti-bacterial and immunomodulatory effect. The exact mechanism of ...
  • Author Correction: A consensus protocol for functional connectivity analysis in the rat brain (Nature Neuroscience, (2023), 26, 4, (673-681), 10.1038/s41593-023-01286-8) 
    Grandjean, Joanes; Desrosiers-Gregoire, Gabriel; Anckaerts, Cynthia; Angeles-Valdez, Diego; Ayad, Fadi; Barrière, David A.; Blockx, Ines; Bortel, Aleksandra; Broadwater, Margaret; Cardoso, Beatriz M.; Célestine, Marina; Chavez-Negrete, Jorge E.; Choi, Sangcheon; Christiaen, Emma; Clavijo, Perrin; Colon-Perez, Luis; Cramer, Samuel; Daniele, Tolomeo; Dempsey, Elaine; Diao, Yujian; Doelemeyer, Arno; Dopfel, David; Dvořáková, Lenka; Falfán-Melgoza, Claudia; Fernandes, Francisca F.; Fowler, Caitlin F.; Fuentes-Ibañez, Antonio; Garin, Clément M.; Gelderman, Eveline; Golden, Carla E.M.; Guo, Chao C.G.; Henckens, Marloes J.A.G.; Hennessy, Lauren A.; Herman, Peter; Hofwijks, Nita; Horien, Corey; Ionescu, Tudor M.; Jones, Jolyon; Kaesser, Johannes; Kim, Eugene; Lambers, Henriette; Lazari, Alberto; Lee, Sung Ho; Lillywhite, Amanda; Liu, Yikang; Liu, Yanyan Y.; López -Castro, Alejandra; López-Gil, Xavier; Ma, Zilu; MacNicol, Eilidh; Madularu, Dan; Mandino, Francesca; Marciano, Sabina; McAuslan, Matthew J.; McCunn, Patrick; McIntosh, Alison; Meng, Xianzong; Meyer-Baese, Lisa; Missault, Stephan; Moro, Federico; Naessens, Daphne M.P.; Nava-Gomez, Laura J.; Nonaka, Hiroi; Ortiz, Juan J.; Paasonen, Jaakko; Peeters, Lore M.; Pereira, Mickaël; Perez, Pablo D.; Pompilus, Marjory; Prior, Malcolm; Rakhmatullin, Rustam; Reimann, Henning M.; Reinwald, Jonathan; Del Rio, Rodrigo Triana; Rivera-Olvera, Alejandro; Ruiz-Pérez, Daniel; Russo, Gabriele; Rutten, Tobias J.; Ryoke, Rie; Sack, Markus; Salvan, Piergiorgio; Sanganahalli, Basavaraju G.; Schroeter, Aileen; Seewoo, Bhedita J.; Selingue, Erwan; Seuwen, Aline; Shi, Bowen; Sirmpilatze, Nikoloz; Smith, Joanna A.B.; Smith, Corrie; Sobczak, Filip; Stenroos, Petteri J.; Straathof, Milou; Strobelt, Sandra; Sumiyoshi, Akira; Takahashi, Kengo; Torres-García, Maria E.; Tudela, Raul; van den Berg, Monica; van der Marel, Kajo; van Hout, Aran T.B.; Vertullo, Roberta; Vidal, Benjamin; Vrooman, Roël M.; Wang, Victora X.; Wank, Isabel; Watson, David J.G.; Yin, Ting; Zhang, Yongzhi; Zurbruegg, Stefan; Achard, Sophie; Alcauter, Sarael; Auer, Dorothee P.; Barbier, Emmanuel L.; Baudewig, Jürgen; Beckmann, Christian F.; Beckmann, Nicolau; Becq, Guillaume J.P.C.; Blezer, Erwin L.A.; Bolbos, Radu; Boretius, Susann; Bouvard, Sandrine; Budinger, Eike; Buxbaum, Joseph D.; Cash, Diana; Chapman, Victoria; Chuang, Kai Hsiang; Ciobanu, Luisa; Coolen, Bram F.; Dalley, Jeffrey W.; Dhenain, Marc; Dijkhuizen, Rick M.; Esteban, Oscar; Faber, Cornelius; Febo, Marcelo; Feindel, Kirk W.; Forloni, Gianluigi; Fouquet, Jérémie; Garza-Villarreal, Eduardo A.; Gass, Natalia; Glennon, Jeffrey C.; Gozzi, Alessandro; Gröhn, Olli; Harkin, Andrew; Heerschap, Arend; Helluy, Xavier; Herfert, Kristina; Heuser, Arnd; Homberg, Judith R.; Houwing, Danielle J.; Hyder, Fahmeed; Ielacqua, Giovanna Diletta; Jelescu, Ileana O.; Johansen-Berg, Heidi; Kaneko, Gen; Kawashima, Ryuta; Keilholz, Shella D.; Keliris, Georgios A.; Kelly, Clare; Kerskens, Christian; Khokhar, Jibran Y.; Kind, Peter C.; Langlois, Jean Baptiste; Lerch, Jason P.; López-Hidalgo, Monica A.; Manahan-Vaughan, Denise; Marchand, Fabien; Mars, Rogier B.; Marsella, Gerardo; Micotti, Edoardo; Muñoz-Moreno, Emma; Near, Jamie; Niendorf, Thoralf; Otte, Willem M.; Pais-Roldán, Patricia; Pan, Wen Ju; Prado-Alcalá, Roberto A.; Quirarte, Gina L.; Rodger, Jennifer; Rosenow, Tim; Sampaio-Baptista, Cassandra; Sartorius, Alexander; Sawiak, Stephen J.; Scheenen, Tom W.J.; Shemesh, Noam; Shih, Yen Yu Ian; Shmuel, Amir; Soria, Guadalupe; Stoop, Ron; Thompson, Garth J.; Till, Sally M.; Todd, Nick; Van Der Linden, Annemie; van der Toorn, Annette; van Tilborg, Geralda A.F.; Vanhove, Christian; Veltien, Andor; Verhoye, Marleen; Wachsmuth, Lydia; Weber-Fahr, Wolfgang; Wenk, Patricia; Yu, Xin; Zerbi, Valerio; Zhang, Nanyin; Zhang, Baogui B.; Zimmer, Luc; Devenyi, Gabriel A.; Chakravarty, M. Mallar; Hess, Andreas (Nature Research, 2023-06)
    In the version of this article initially published, Clément M. Garin was presented in the author list without a middle initial. The name has been amended in the HTML and PDF versions of the article.
  • Genetic variability in sporadic amyotrophic lateral sclerosis 
    Van Daele, Sien Hilde; Moisse, Matthieu; van Vugt, Joke J F A; Zwamborn, Ramona A J; van der Spek, Rick; van Rheenen, Wouter; Van Eijk, Kristel; Kenna, Kevin; Corcia, Philippe; Vourc'h, Patrick; Couratier, Philippe; Hardiman, Orla; McLaughin, Russell; Gotkine, Marc; Drory, Vivian; Ticozzi, Nicola; Silani, Vincenzo; Ratti, Antonia; de Carvalho, Mamede; Mora Pardina, Jesús S; Povedano, Monica; Andersen, Peter M; Weber, Markus; Başak, Nazli A; Shaw, Chris; Shaw, Pamela J; Morrison, Karen E; Landers, John E; Glass, Jonathan D; van Es, Michael; van den Berg, Leonard H; Al-Chalabi, Ammar; Veldink, Jan; Van Damme, Philip (Oxford University Press, 2023-09-01)
    With the advent of gene therapies for amyotrophic lateral sclerosis (ALS), there is a surge in gene testing for this disease. Although there is ample experience with gene testing for C9orf72, SOD1, FUS and TARDBP in familial ...
  • Development and Evaluation of a Simulation-Based Algorithm to Optimize the Planning of Interim Analyses for Clinical Trials in ALS 
    van Unnik, Jordi W J; Nikolakopoulos, Stavros; Eijkemans, Marinus J C; Gonzalez-Bermejo, Jésus; Bruneteau, Gaelle; Morelot-Panzini, Capucine; van den Berg, Leonard H; Cudkowicz, Merit E; McDermott, Christopher J; Similowski, Thomas; van Eijk, Ruben P A (Lippincott Williams & Wilkins, 2023-06-06)
    BACKGROUND AND OBJECTIVES: Late-phase clinical trials for neurodegenerative diseases have a low probability of success. In this study, we introduce an algorithm that optimizes the planning of interim analyses for clinical ...
  • De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders 
    zhang (American Association for the Advancement of Science, 2022-08-19)
    Stress granules (SGs) are cytoplasmic assemblies in response to a variety of stressors. We report a new neurodevelopmental disorder (NDD) with common features of language problems, intellectual disability, and behavioral ...
  • Methotrexate therapy associated with a reduced rate of new-onset uveitis in patients with biological-naïve juvenile idiopathic arthritis 
    van Straalen, Joeri W; Akay, Görkem; Kouwenberg, Carlyn V; de Roock, Sytze; Kalinina Ayuso, Viera; Wulffraat, Nico M; de Boer, Joke; Swart, Joost F (BMJ Publishing Group, 2023-04-24)
    OBJECTIVE: To study the effect of methotrexate (MTX) therapy on new-onset uveitis in patients with biological-naïve juvenile idiopathic arthritis (JIA). METHODS: In this matched case-control study, we compared MTX exposure ...
  • Factors influencing motivation of patients diagnosed with depression to have electroconvulsive therapy 
    Schuurmans, Rona G.M.; Krijnen de Bruin, Esther; van Asperen, G. C.Roselie; Poslawsky, Irina E.; Hafsteinsdóttir, Thóra B.; van Meijel, Berno (Wiley-Blackwell, 2023-10)
    What is known on the subject?: The clinical effect of electroconvulsive therapy (ECT) has been confirmed for a majority of patients with several psychiatric disorders. ECT is mostly used in patients with severe depression. ...
  • Interventions for improving psychosocial well-being after stroke: A systematic review 
    van Nimwegen, Dagmar; Hjelle, Ellen Gabrielsen; Bragstad, Line Kildal; Kirkevold, Marit; Sveen, Unni; Hafsteinsdóttir, Thóra; Schoonhoven, Lisette; Visser-Meily, Johanna; de Man-van Ginkel, Janneke M. (Elsevier Limited, 2023-06)
    Background: Up to one third of all stroke patients suffer from one or more psychosocial impairments. Recognition and treatment of these impairments are essential in improving psychosocial well-being after stroke. Although ...
  • Assessing heterogeneity of electronic health-care databases: A case study of background incidence rates of venous thromboembolism 
    Russek, Martin; Quinten, Chantal; de Jong, Valentijn M.T.; Cohet, Catherine; Kurz, Xavier (John Wiley & Sons Inc., 2023-09)
    Purpose: Heterogeneous results from multi-database studies have been observed, for example, in the context of generating background incidence rates (IRs) for adverse events of special interest for SARS-CoV-2 vaccines. In ...
  • Evolutionary conservation of the fidelity of transcription 
    Chung, Claire; Verheijen, Bert M; Navapanich, Zoe; McGann, Eric G; Shemtov, Sarah; Lai, Guan-Ju; Arora, Payal; Towheed, Atif; Haroon, Suraiya; Holczbauer, Agnes; Chang, Sharon; Manojlovic, Zarko; Simpson, Stephen; Thomas, Kelley W; Kaplan, Craig; van Hasselt, Peter; Timmers, Marc; Erie, Dorothy; Chen, Lin; Gout, Jean-Franćois; Vermulst, Marc (Nature Publishing Group, 2023-03-20)
    Accurate transcription is required for the faithful expression of genetic information. However, relatively little is known about the molecular mechanisms that control the fidelity of transcription, or the conservation of ...
  • Development of a compounded propofol nanoemulsion using multiple non-invasive process analytical technologies 
    Rooimans, T; Damen, M; Markesteijn, C M A; Schuurmans, C C L; de Zoete, N H C; van Hasselt, P M; Hennink, W E; van Nostrum, C F; Hermes, M; Besseling, R; Vromans, H (Elsevier, 2023-06-10)
    Propofol is the preferred anaesthetic for induction and maintenance of sedation in critically ill mechanically ventilated COVID-19 patients. However, during the outbreak of the COVID-19 pandemic, regular supply chains could ...