van der Kemp, Jet; Kruithof, Willeke J.; Nijboer, Tanja C.W.; van Bennekom, Coen A.M.; van Heugten, Caroline; Visser-Meily, Johanna M.A.(Psychology Press Ltd, 2019-04-21)
A large proportion of stroke patients are unable to return to work (RTW), although figures vary greatly. A total of 121 mild-to-moderate stroke patients, who had a paid job at the time of their stroke were included (a) to ...
Buddeke, Josefien; Gernaat, Sofie A. M.; Bots, Michiel L.; van den Bongard, Desiree H. J. G.; Grobbee, Diederick E.; Vaartjes, Ilonca; Verkooijen, Helena M.(BMJ Publishing Group, 2019-05)
Objectives: To investigate trends in cardiovascular disease (CVD) risk following breast cancer using national registry data. Methods: A nationwide cohort study was conducted, comprising 163 881 women with in situ (7.6%) ...
In patients with prostate cancer, metastases mostly develop in bone, lung, liver, pleura and adrenal glands. Prostate carcinoma metastases to the ureter are very rare, and the peritoneum is an even rarer site of prostate ...
Kopper, Oded; de Witte, Chris J; Lõhmussaar, Kadi; Valle-Inclan, Jose Espejo; Hami, Nizar; Kester, Lennart; Balgobind, Anjali Vanita; Korving, Jeroen; Proost, Natalie; Begthel, Harry; van Wijk, Lise M; Revilla, Sonia Aristín; Theeuwsen, Rebecca; van de Ven, Marieke; van Roosmalen, Markus J; Ponsioen, Bas; Ho, Victor W H; Neel, Benjamin G; Bosse, Tjalling; Gaarenstroom, Katja N; Vrieling, Harry; Vreeswijk, Maaike P G; van Diest, Paul J; Witteveen, Petronella O; Jonges, Trudy; Bos, Johannes L; van Oudenaarden, Alexander; Zweemer, Ronald P; Snippert, Hugo J G; Kloosterman, Wigard P; Clevers, Hans(Nature Publishing Group, 2019-05)
Ovarian cancer (OC) is a heterogeneous disease usually diagnosed at a late stage. Experimental in vitro models that faithfully capture the hallmarks and tumor heterogeneity of OC are limited and hard to establish. We present ...
The present thesis has two principal aims: 1) to evaluate the clinical performance of a novel reservoir-based elution-technology and 2) to gain knowledge about optimizing dual antiplatelet therapy in patients with ischemic ...
de Groot, Reilly Jeremy(Utrecht University, 2019-09-03)
This thesis describes the effect of oral oncological intervention on masticatory performance. It represents an attempt to study many factors that either improve or deteriorate masticatory performance, based on both objective ...
Heesterbeek, Dani Anne Cornelia(Utrecht University, 2019-08-29)
Infections with bacteria form an increasing threat for human health. This is mainly due to the fact that bacteria develop mechanism to resist killing by existing antibiotics. In order to find alternatives to treat infections ...
Braat, Arthur Johannes Anthonius Theodorus(Utrecht University, 2019-09-20)
Neuroendocrine Neoplasms (NEN) is a generic term for a class of rare tumours, consisting of an array of many different tumor types. Similar to the trends noticed internationally, in the Dutch population the incidence of ...
Soto Ruiz De La Torre, Mar(Utrecht University, 2019-08-29)
Errors in chromosome segregation contribute to tumor heterogeneity and evolution by driving karyotype diversification. However, it is poorly understood how cancer cells tolerate abnormal karyotypes so well. In this thesis ...
Favié, Laurentius Martinus Adrianus(Utrecht University, 2019-09-05)
This thesis describes research into potential neuroprotective agents in children born with a severe oxygen shortage at birth (perinatal asphyxia). Standard treatment for this condition is therapeutic hypothermia. During ...
van Mierlo, Hans Christian(Utrecht University, 2019-08-28)
In chapter 1 an overview of the literature that links schizophrenia and the immune system is given. Previous studies have reported an increased prevalence of antinuclear antibodies in patients with schizophrenia. In chapter ...
This thesis investigated the association between diet-related environmental impact and health. Data were from 40,000 Dutch participants enrolled in the EPIC-NL cohort with available dietary data at baseline (1993-1997) and ...
Kerckhoffs, Monika C.; Kant, Matthijs; van Delden, Johannes J. M.; Hooft, Lotty; Kesecioglu, Jozef; van Dijk, Diederik(Elsevier BV, 2019-06)
Purpose Many patients in the Intensive Care Unit (ICU) die after a decision to withhold or withdraw treatment. To ensure that for each patient the appropriate decision is taken, a careful decision-making process is required. ...
Jabbarian, Lea J.; Maciejewski, Renee C.; Maciejewski, Paul K.; Rietjens, Judith A. C.; Korfage, Ida J.; van der Heide, Agnes; van Delden, Johannes J. M.; Prigerson, Holly G.(Elsevier Inc., 2019-06)
Context Stability of patients' treatment preferences has important implications for decisions about concurrent and future treatment. Objectives To examine the stability of treatment preferences and correlates among patients ...
van Lier, Alies; de Gier, Brechje; McDonald, Scott A; Mangen, Marie-Josée J; van Wijhe, Maarten; Sanders, Elisabeth A M; Kretzschmar, Mirjam E; van Vliet, Hans; de Melker, Hester E(Centre Europeen pour la Surveillance Epidemiologique du SIDA, 2019-05)
IntroductionEstimating burden of disease (BoD) is an essential first step in the decision-making process on introducing new vaccines into national immunisation programmes (NIPs). For varicella, a common vaccine-preventable ...
van Wees, Daphne A; den Daas, Chantal; Kretzschmar, Mirjam E E; Heijne, Janneke C M(Public Library of Science, 2019-06-01)
INTRODUCTION: Response rates in health research are declining, and low response rates could result in biased outcomes when population characteristics of participants systematically differ from the non-respondents. Few ...
Elving-Kokke, K. H.; Sas-Meertens, M. A., V; de Beer, F. M.; van Rijn, L. J.; de Boer, J. H.; Visser, E-S(Elsevier, 2019-02)
Purpose Ocular hypotony after trabeculectomy may be treated medically, surgically and with a tamponade. Three cases are reported in which a scleral lens was applied to treat ocular hypotony after mitomycin C (MMC) augmented ...
Haasnoot, Anne-Mieke J. W.; Kuiper, Jonas J. W.; de Boer, Joke H.(Expert Reviews Ltd., 2019-06-03)
Introduction: Uveitis is a sight-threatening eye inflammation and common manifestation of juvenile idiopathic arthritis (JIA). New biomarkers that can predict uveitis are needed to alleviate personalized clinical screening. ...
Background Gender differences in symptomatology in chronic schizophrenia and first episode psychosis patients have often been reported. However, little is known about gender differences in those at risk of psychotic ...