Extracranial carotid artery aneurysms (ECAA) are rare and have an unknown incidence. Little is known about its natural clinical course, optimal treatment and its association with other aneurysms. The average age of patients ...
Developmental disorders such as autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) are extremely debilitating. Furthermore, their prevalence has risen exponentially over the last decades. ...
Breast cancer is the most common type of cancer in women worldwide. In the Netherlands, over 14.000 women a year are diagnosed with invasive breast cancer. Fortunately, the prognosis of breast cancer patients is improving ...
Adequate drug storage is essential to guarantee the drug’s quality, safety and efficacy until the expiry date. In contrast with the tight regulations for drug storage and transport between drug companies, wholesalers and ...
Calor (increased heat), rubor (redness), tumor (swelling) and dolor (pain) are the four cardinal signs of inflammation, which were described by Celsus during the first century. Later, a fifth sign was added to Celsus tetrad, ...
Patients with cancer are at risk for post influenza complications due to their underlying disease as well as their (immunosuppressive) treatment; therefore influenza vaccination is recommended to prevent influenza infections. ...
Sjögren’s syndrome (SjS) is a chronic, systemic autoimmune disorder characterized by dryness of mainly the eyes and mouth in association with lymphocytic infiltration of the exocrine glands. In addition to the dryness ...
Snijders, Clara; de Nijs, Laurence; Baker, Dewleen G.; Hauger, Richard L.; van den Hove, Daniel; Kenis, Gunter; Nievergelt, Caroline M.; Boks, Marco P.; Vermetten, Eric; Gage, Fred H.; Rutten, Bart P.F.(Springer International Publishing AG, 2018-01-01)
Post-traumatic stress disorder (PTSD) is a psychiatric disorder that can develop following exposure to or witnessing of a (potentially) threatening event. A critical issue is to pinpoint the (neuro)biological mechanisms ...
Ciliopathies comprise a large number of hereditary human diseases and syndromes caused by mutations resulting in dysfunction of either primary or motile cilia. Both types of cilia share a similar architecture. While primary ...
Haemodiafiltration (HDF) combines diffusive and convective solute removal in a single treatment session. HDF provides a greater removal of higher molecular weight uraemic retention solutes than conventional high-flux ...
van Galen, Karin P M; Timmer, Merel; de Kleijn, Piet; Leebeek, Frank W G; Foppen, Wouter; Schutgens, Roger E G; Eikenboom, Jeroen; Meijer, Karina; Fijnvandraat, Karin; Laros-van Gorkom, Britta A P; Twisk, Jos W; Mauser-Bunschoten, Eveline P; Fischer, Kathelijn; WiN Studygroup(2018)
Long-term outcome after joint bleeds in von Willebrand disease (VWD) (von Willebrand factor activity ≤ 30 IU/dL) could differ from moderate or severe haemophilia A (HA) (factor VIII [FVIII] 1-5 IU/dL or FVIII < 1 IU/dL). ...
De Jonge, E.; De Wilde, R. B.P.; Juffermans, N. P.; Oostdijk, E. A.N.; Bernards, A. T.; Van Essen, E. H.R.; Kuijper, E. J.; Visser, C. E.; Kesecioglu, J.; Bonten, M. J.M.(2018-09-29)
Background: Selective decontamination of the digestive tract (SDD) and selective oropharyngeal decontamination (SOD) reduce colonization with antibiotic-resistant Gram-negative bacteria (ARGNB), incidence of nosocomial ...
Relvas, Lia Judice M.; Antoun, Joelle; de Groot-Mijnes, Jolanda D.F.; Motulsky, Elie; Ten Dam-Van Loon, Ninette H.; Makhoul, Dorine; Willermain, François; Caspers, Laure(2018-01-02)
Purpose: To evaluate diagnostic methods and clinical signs of CMV anterior uveitis (AU), a rarely described entity in Europe. Methods: We included patients with clinical characteristics of CMV AU and positive PCR and/or ...
Wensing, Barbara; Mochizuki, Manabu; De Boer, Joke H.(2018-04-03)
Purpose: The aim of this study is to describe the clinical characteristics of molecularly proven Herpes simplex virus (HSV) anterior uveitis. Methods: The literature on HSV anterior uveitis whereby the diagnosis was confirmed ...
Hermans, Frederik J R; Schuit, Ewoud; Bekker, Mireille N; Woiski, Mallory; de Boer, Marjon A; Sueters, Marieke; Scheepers, Hubertina C J; Franssen, Maureen T M; Pajkrt, Eva; Mol, Ben Willem J; Kok, Marjolein(2018-09)
OBJECTIVE: To assess the effectiveness of cervical pessary in reducing the rate of preterm birth in women at high risk for preterm birth who did not deliver after an episode of threatened preterm labor. METHODS: In a ...