Parkinson’s disease (PD) is a complex and multifaceted illness possibly linked to many environmental factors. This thesis contributes to the existing knowledge on the role of environmental exposures in PD etiology within ...
KRAS (Kirsten Rat Sarcoma virus) is the most frequently mutated oncogene in human cancers. Mutation of the KRAS protein was prevalent in patients with pancreatic cancer, colorectal cancer, lung cancer, and multiple myeloma. ...
In our changing world, humans experience increasingly the negative consequences of
floods and droughts. Seasonal forecasts with lead times of several months, and covering larger areas are necessary to increase global ...
Cells have diverse morphologies and correspondingly diverse microtubule networks crucial for their functions. The microtubules in these arrays can differ in terms of their dynamic behaviour or lifetime (i.e., their stability ...
The original aim of the research presented in this thesis was to uncover new (f)MRI-based biomarkers of impulsive aggression problems in (post-)active military personnel. In that regard, the work presented here did not ...
Clinical trials evaluate the effects of medicines in people. Decentralized clinical trial (DCT) approaches aim to bring clinical trial activities closer to participants’ homes, for example by using wearables and apps to ...
This dissertation offers an exploration of sati, an Indian practice of widow burning, as an evolving site of memory in the period between 1850 and 1900 in Britain. The study shows how sati evolved into a resource for ...
Plastic pollution in the world’s oceans is a critical issue with wide-reaching effects on marine life, human health, and economies dependent on coastal tourism and fisheries. The problem extends beyond visible impacts to ...
Dit proefschrift is gewijd aan de Sidrat al-Muntahā, een nog niet gepubliceerd werk geschreven door Taqī al-Dīn ibn Maʿrūf (1526-1585 n.C.), een van de belangrijkste ingenieurs en astronomen uit de Ottomaanse periode en ...
The diversity of life on Earth is immense, with organisms colonizing even some of the most extreme habitats on the planet. Remarkably, despite such immense diversity within the biosphere, all living things are united by a ...
As the title of this thesis suggests, we study how does the complexity of problems change if we add some restrictions to them. In order to achieve this, we use the framework of parameterized complexity. In contrast to ...
The CRISPR/Cas system is a powerful tool for both scientific research and potential therapeutic strategies for inherited diseases. This PhD thesis investigated the feasibility of cell-penetrating peptide-mediated direct ...
We study the behavior of gradients squared of Gaussian fields on different graphs and their relationship with certain lattice models. In particular, we study commutative and anti-commutative squared Gaussian fields, and ...
In recent years, there has been a slow and steady shift in the gender status quo, whereby we are increasingly acknowledging that there are more than two ways for people to define their gender. Shortly before I began my ...
Educational games are widely used in education and previous research has indicated the overall effectiveness of games in improving students’ cognition, motivation, and behavior. However, little is known about whether the ...
Bienenmann, Roel Laurentius Maria(Utrecht University, 2024-09-10)
Man-made chemicals - from materials to pharmaceuticals - are everywhere in our modern world. These chemicals need to be produced and to do so, chemists need the right chemical tools. These tools are known as catalysts. ...
This thesis sets out to analyse how democratic praxis in grassroots agrifood collectives contributes to the fostering of sustainability transformations that take a critical stance towards capitalism and the state. I analyse ...
In this dissertation, I investigate how being different from the majority of one’s colleagues shapes social inclusion perceptions at work. In Chapter 1, I introduce the relational demography approach and ingroup projection ...
String theory is a proposal for a description of nature on the smallest length scales, where both quantum mechanics and gravity are expected to play an essential role. A curious feature of the theory is that its basic ...
Houben, Rosa Maria Allegonda Catharina(Utrecht University, 2024-09-03)
The infectious agents Streptococcus equi subspecies equi (S. equi, the cause of strangles) and EHV-1 (a cause of mild cold-like symptoms, but also of abortion and neurological disease) occur frequently in horses in the ...