• Legislative differentiation: reconciling uniformity and diversity in EU legislation 

  Hübner, Michael (Utrecht University, 2024-09-20)
• Nanoparticle synthesis and self-assembly: Tailoring supraparticles for catalysis 

  Brouwer, Jacoba Henrica (Utrecht University, 2024-09-24)

  Heterogenous catalysts are important for the production of everyday life products, ranging from plastics to pharmaceuticals and energy. Understanding how to improve these catalyst materials allows for the optimization of ...
• Parameterized Graph Problems: Counting, the Tutte Polynomial and Logarithmic Space 

  Mannens, Isja Maria Emiel (Utrecht University, 2024-10-21)

  In this thesis we study the computational complexity of various parameterized graph problems. The complexity of a problem measures the difficulty of a problem as the amount of time it costs to solve it. A parameterized ...
• Alternatives to animal research: from in vitro to ex vivo liver models 

  Krüger, Melanie (Utrecht University, 2024-10-08)

  Understanding the critical importance of reducing reliance on traditional research animal models in liver disease research, this thesis focused on advancing the development of more sophisticated, physiologically relevant, ...
• Connected Cities: Deciphering City Relationships Using Collocation Analysis 

  Wang, Tongjing (Utrecht University, 2024-09-24)

  Cities form a variety of relationships that facilitate cooperative development. While it is well-recognized that intercity relationships play critical roles in boosting city performance and shaping regional policy, conducting ...
• Antibiotic Action Beyond Simple Target Binding: Exploring Supramolecular Mechanisms of Membrane-Active Antibiotics 

  Derks, Maik Georgi Niek (Utrecht University, 2024-09-23)

  Antibiotics are cornerstone drugs of modern medicine. However, their effectiveness is declining rapidly due to the emergence and spread of antimicrobial resistance. It is therefore critical that new antibiotics are developed ...
• 'Die zorg droeg voor dit goede verloop': De professionalisering en modernisering van de ondersteuning bij de Utrechtse universiteit in historisch perspectief (1876 – 2011) 

  Nugteren, Bastiaan (Utrecht University, 2024-10-11)

  The dissertation ‘Who ensured this good progress’ (‘Die zorg droeg voor dit goede verloop’) describes the history of the support staff at Utrecht University between 1876 and 2011, and the manner in which their services ...
• Exposomics to unravel Parkinson’s disease etiology 

  Zhao, Yujia (Utrecht University, 2024-10-08)

  Parkinson’s disease (PD) is a complex and multifaceted illness possibly linked to many environmental factors. This thesis contributes to the existing knowledge on the role of environmental exposures in PD etiology within ...
• LC-MS/MS bioanalysis and murine biotransformation of covalent targeted KRASG12C inhibitors in oncology 

  Retmana, Irene Anindyajati (Utrecht University, 2024-09-18)

  KRAS (Kirsten Rat Sarcoma virus) is the most frequently mutated oncogene in human cancers. Mutation of the KRAS protein was prevalent in patients with pancreatic cancer, colorectal cancer, lung cancer, and multiple myeloma. ...
• Skill and value of global seasonal streamflow forecasts 

  Candogan Yossef, Naze (Utrecht University, 2024-09-06)

  In our changing world, humans experience increasingly the negative consequences of floods and droughts. Seasonal forecasts with lead times of several months, and covering larger areas are necessary to increase global ...
• Navigating microtubule diversity: Insights into microtubule stability and orientation 

  Iwanski, Malina Karen (Utrecht University, 2024-09-25)

  Cells have diverse morphologies and correspondingly diverse microtubule networks crucial for their functions. The microtubules in these arrays can differ in terms of their dynamic behaviour or lifetime (i.e., their stability ...
• Digging for Fool's Gold: Functional MRI of the Amygdala in (Post-)Active Military Personnel with Impulsive Aggression Problems 

  Varkevisser, Tim (Utrecht University, 2024-09-27)

  The original aim of the research presented in this thesis was to uncover new (f)MRI-based biomarkers of impulsive aggression problems in (post-)active military personnel. In that regard, the work presented here did not ...
• Bringing clinical trials home: European regulatory perspectives on decentralized clinical trial approaches 

  Jong, Amos Jochanan de (Utrecht University, 2024-10-07)

  Clinical trials evaluate the effects of medicines in people. Decentralized clinical trial (DCT) approaches aim to bring clinical trial activities closer to participants’ homes, for example by using wearables and apps to ...
• Sati in Britain, 1850-1900: An Evolving Site of Memory 

  Järleberg, Maninder (Utrecht University, 2024-09-25)

  This dissertation offers an exploration of sati, an Indian practice of widow burning, as an evolving site of memory in the period between 1850 and 1900 in Britain. The study shows how sati evolved into a resource for ...
• Microbial colonization, biodegradation, and photodegradation of marine plastics in (sub)tropical waters: Tracing bacteria-plastic interactions in the Mediterranean and Caribbean Sea 

  Goudriaan, Maaike (Utrecht University, 2024-10-02)

  Plastic pollution in the world’s oceans is a critical issue with wide-reaching effects on marine life, human health, and economies dependent on coastal tourism and fisheries. The problem extends beyond visible impacts to ...
• Astronomy in Sixteenth-Century Istanbul: Taqi al-Din ibn Ma'ruf (d.1585) and his unfinished astronomical handbook Sidrat al-Muntaha 

  Şen, Hüseyin (Utrecht University, 2024-09-18)

  Dit proefschrift is gewijd aan de Sidrat al-Muntahā, een nog niet gepubliceerd werk geschreven door Taqī al-Dīn ibn Maʿrūf (1526-1585 n.C.), een van de belangrijkste ingenieurs en astronomen uit de Ottomaanse periode en ...
• Tracing the evolutionary history of cellular life 

  Mahendrarajah, Tara Avanthi (Utrecht University, 2024-09-13)

  The diversity of life on Earth is immense, with organisms colonizing even some of the most extreme habitats on the planet. Remarkably, despite such immense diversity within the biosphere, all living things are united by a ...
• Parameterized Complexity of Restricted Variants of Some Classical Problems 

  Szilágyi, Krisztina (Utrecht University, 2024-09-18)

  As the title of this thesis suggests, we study how does the complexity of problems change if we add some restrictions to them. In order to achieve this, we use the framework of parameterized complexity. In contrast to ...
• Breaching Barriers in Gene Editing: Getting CRISPR/Cas9 Ribonucleoproteins into the Cell with Cell Penetrating Peptides 

  Öktem, Mert (Utrecht University, 2024-09-09)

  The CRISPR/Cas system is a powerful tool for both scientific research and potential therapeutic strategies for inherited diseases. This PhD thesis investigated the feasibility of cell-penetrating peptide-mediated direct ...
• Bosonic and fermionic structures in lattice models 

  Rapoport, Alan (Utrecht University, 2024-09-17)

  We study the behavior of gradients squared of Gaussian fields on different graphs and their relationship with certain lattice models. In particular, we study commutative and anti-commutative squared Gaussian fields, and ...

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