• Geneesmiddelen voor Geavanceerde Therapie (ATMP’s) in Nederland: Veldverkenning, Knelpuntanalyse en Activiteitenkaart 

  Gort, Jurriaan; Hattem, Christine van; Bloem, Lourens; Ham, Renske ten (2023-12)
• Een cultuur vol liederen, liedkunst vol cultuur: De positie van vrouwen in Hindostaanse liedkunst 

  Ramcharan, Anita (Utrecht University, 2023-12-21)

  When Indian people in de nineteenth century left British India and moved to Surinam they didn’t prepare themselves to build up a Hindu society in Surinam or in The Netherlands. Most of them worked as indentured labours for ...
• Glycoremodeling of monoclonal antibodies 

  Bosman, Gerlof Peter (Utrecht University, 2023-12-19)

  Monoclonal antibodies (mAbs) are therapeutic glycoproteins mostly used in the areas of oncology and immunology. The structure of an mAb can be divided into the Fab fragment and the Fc region. The Fc region can be subdivided ...
• Neural networks for stochastic control and decision making in mathematical finance 

  Andersson, Kristoffer Herbert (Utrecht University, 2023-12-18)

  As the title suggests, this thesis is devoted to machine learning algorithms for stochastic control with applications in mathematical finance. In the first two chapters, we utilize neural networks to find the optimal ...
• Tracing histone modification dynamics in single cells during differentiation and early development 

  Viñas Gaza, Helena (Utrecht University, 2023-12-18)

  Epigenetics is derived from the Greek prefix -epi that means “around” and the word genetics which is the study of genes. Therefore, epigenetics is the study of the effects that occur around the DNA helix that have an impact ...
• Targeting amino acid-metabolizing enzymes for cancer immunotherapy and treatment of Parkinson’s disease 

  Grobben, Yvonne (Utrecht University, 2023-12-18)

  Metabolic homeostasis of amino acids is fundamental to human health and development. Accordingly, altered amino acid metabolism has been found to contribute to the pathogenesis of a variety of diseases, including cancer ...
• Gelfand-Levitan-Marchenko and model order reduction methods in inverse scattering 

  Tataris, Andreas (Utrecht University, 2023-12-15)

  Inverse scattering problems arise in many applications, especially in imaging. In this thesis we studied frequency domain inverse scattering problems for the Helmholtz and the Schrödinger operators using both classical ...
• History of the Futures: The evolution, credibility & policy relevance of the emission scenarios informing the Intergovernmental Panel on Climate Change (IPCC) 1990-2022 

  Pedersen, Jiesper Strandsbjerg Tristan (Utrecht University, 2023-12-13)

  Model-based scenarios represent a backbone for future climate change analyses, aiming to inform policy responses and designs. Emission scenarios play a crucial role, e.g., in assessing mitigation strategies evaluated by ...
• From Monomers to Condensates: Golgi-Associated plant Pathogenesis Related protein 1 (GAPR-1) Oligomerization in Saccharomyces cerevisiae 

  Sirati, Nafiseh (Utrecht University, 2023-12-11)

  Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) is a peripheral membrane protein located on the cytosolic leaflet of the Golgi apparatus in mammalian cells. GAPR-1 belongs to the CAP (cysteine-rich secretory ...
• Bioengineering hepatic organoids: Development of an alternative model for liver toxicity 

  Bouwmeester, Manon Christel (Utrecht University, 2023-12-14)

  The liver is the major organ involved in the biotransformation of drugs and other chemicals. Disturbance of this process can lead to accumulation of toxic compounds and is therefore a key determinant in liver toxicity. ...
• Contextualising access to essential medicines: Lessons learned from East and Southern Africa 

  Ooms, Gaby Isabelle (Utrecht University, 2023-12-13)

  Worldwide, more than 2 billion people lack access to medicines, leading to more than 10 million people dying needlessly as a result of this lack of access. Most of these deaths occur in Sub-Saharan Africa. To gain a deeper ...
• Biogeomorphology shaping coastal and estuarine systems: the long-term development of landscapes 

  Boechat Albernaz, Marcio (Utrecht University, 2023-12-08)

  Coastal and estuarine environments are home to a wide variety of habitats and ecosystems. They provide ecosystem services such as nursery grounds and habitats for (non-)commercial fishes and other aquatic species, and offer ...
• De marktconforme verzorgingsstaat: 1989-2008 

  Woltring, Naomi Marianne (Utrecht University, 2023-12-08)

  Between 1989 and 2008 a far-reaching reform of the Dutch economic, housing and social security policies took place, in neoliberal direction. The Dutch welfare state was re-organized in a ‘market conforming’ way. The reforms ...
• Long-term dynamics of tidal sand waves 

  Krabbendam, Janneke Martha (Utrecht University, 2023-12-06)

  Tidal sand waves are bedforms that have been observed at the sandy bed of shallow seas all over the world. They have heights (vertical distance between crest and trough) of several meters and lengths (crest-to-crest distance) ...
• Membrane Effects of Antimicrobial Peptides 

  Wang, Xiaoqi (Utrecht University, 2023-12-06)

  Antimicrobial resistance is becoming an increasing challenge that threatens the human health system. The overuse of antibiotics has led to an acceleration in the emergence of antibiotic-resistant bacteria, the result of ...
• From atoms to photons: Formation and photophysical properties of nanomaterials 

  Prins, Paul Timotheüs (Utrecht University, 2023-12-04)

  Light, radiation in the form of photons, is crucial for life on Earth, serving a multitude of functions, including providing warmth, supporting plant growth, regulating our day-night cycle, and enabling vision. The sun has ...
• Lipid Nanoparticle-Mediated Delivery of CRISPR-Cas9 for Therapeutic Gene Correction 

  Walther, Johanna (Utrecht University, 2023-12-04)

  The thesis “Lipid Nanoparticle-Mediated Delivery of CRISPR-Cas9 for Therapeutic Gene Correction” delves into the potential of CRISPR-Cas9 as a gene therapy tool for treating hereditary disorders. Originally a bacterial ...
• Intrahepatic cholangiocyte organoids for bile-duct tissue engineering and disease modeling 

  Wang, Zhenguo (Utrecht University, 2023-12-04)

  The biliary tract is structurally and functionally a highly complex system in the human body, and is composed of the intra- and extrahepatic bile duct and gallbladder. Bile is initially produced by hepatocytes, secreted ...
• Shedding light on the ‘invisible’ water crisis: Modelling past and future global surface water quality 

  Jones, Edward Russell (Utrecht University, 2023-12-01)

  Clean water is essential for supporting human livelihoods and maintaining ecosystem health. However, our knowledge of water quality is severely impaired by a lack of quantitative information. Being under-monitored and often ...
• Met praktijkgericht onderzoek naar de implementatie van innovaties: Een studie naar de implementatie van zelfmanagementinnovaties voortkomend uit praktijkgericht onderzoek in Nederland 

  Beest, Wilke van (Utrecht University, 2023-12-01)

  This thesis is about the implementation of healthcare innovations in self-management emerging from practice-based research. Innovations to support self-management range from digital tools, such as eHealth applications, to ...

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