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Now showing items 8821-8840 of 95693

Quantity and economic value of unused oral anti-cancer and biological disease-modifying anti-rheumatic drugs among outpatient pharmacy patients who discontinue therapy

Bekker, C L; Melis, E J; Egberts, A C G; Bouvy, M L; Gardarsdottir, H; van den Bemt, B J F (Elsevier, 2019)

BACKGROUND: Patients sometimes discontinue the use of expensive oral anti-cancer drug (OACD) or biological disease-modifying anti-rheumatic drug (bDMARD) therapies early, leading to medication waste if the patient has not ...
Biofabrication of reinforced 3D-scaffolds using two-component hydrogels

Boere, Kristel W. M.; Blokzijl, Maarten M.; Visser, Jetze; Linssen, J. Elder A.; Malda, Jos; Hennink, Wim E.; Vermonden, Tina (Royal Society of Chemistry, 2015)

Progress in biofabrication technologies is mainly hampered by the limited number of suitable hydrogels that can act as bioinks. Here, we present a new bioink for 3D-printing, capable of forming large, highly defined ...
Medisch-farmaceutische beslisregels en nierfunctie- meting in de openbare apotheek: Wat levert het op?

Heringa, Mette; Van De Steeg-Van Gompel, Caroline H P A; Bouvy, Marcel L. (De Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie, 2017-02-17)

OBJECTIVE To investigate the frequency and management of drug therapy alerts about drug use in patients with (potential) renal impairment, to investigate the contribution of point- of-care testing (PoCT) of renal function ...
Heruitgifte van ongebruikte geneesmiddelen: Een kwalitatief onderzoek onder stakeholders

Bekker, Charlotte L; Gardarsdottir, Helga; Egberts, Toine C.G.; Bouvy, Marcel L.; Van Den Bemt, Bart J.F. (De Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie, 2018-01-12)

BACKGROUND Medication waste has undesirable economic and environmental consequences. This waste is partly unavoidable but might be reduced by redispensing medicines unused by patients. However, there is little knowledge ...
Ovalbumin-Induced Epithelial Activation Directs Monocyte-Derived Dendritic Cells to Instruct Type 2 Inflammation in T Cells Which Is Differentially Modulated by 2'-Fucosyllactose and 3-Fucosyllactose

Zuurveld, Marit; Kiliaan, Pien C J; van Grinsven, Sophie E L; Folkerts, Gert; Garssen, Johan; Van't Land, Belinda; Willemsen, Linette E M (S. Karger AG, 2023)

Allergic sensitization starts with epithelial cell activation driving dendritic cells (DCs) to instruct T helper 2 (Th2) cell polarization. Food allergens trigger intestinal epithelial cell (IEC) activation. Human milk ...
Rapid and cytocompatible cell-laden silk hydrogel formation via riboflavin-mediated crosslinking

Piluso, Susanna; Flores Gomez, Daniela; Dokter, Inge; Moreira Texeira, Liliana; Li, Yang; Leijten, Jeroen; van Weeren, René; Vermonden, Tina; Karperien, Marcel; Malda, Jos (Royal Society of Chemistry, 2020-10-28)

Bioactive hydrogels based on naturally-derived polymers are of great interest for regenerative medicine applications. Among naturally-derived polymers, silk fibroin has been extensively explored as a biomaterial for tissue ...
Butyrate and propionate restore interleukin 13-compromised esophageal epithelial barrier function

Kleuskens, Mirelle T A; Haasnoot, Maria L; Herpers, Bart M; van Ampting, Marleen T J; Bredenoord, Albert J; Garssen, Johan; Redegeld, Frank A; van Esch, Betty C A M (Blackwell Publishing Ltd, 2022-05)

Background: Eosinophilic esophagitis (EoE) is a food allergen driven disease that is accompanied by interleukin (IL) 13 overexpression and esophageal barrier dysfunction allowing transepithelial food allergen permeation. ...
Voorkeuren van patiënten en apothekers bij het afhandelen van geneesmiddelinteracties

Heringa, Mette; Floor-Schreudering, Annemieke; Wouters, Hans; de Smet, Peter A.G.M.; Bouvy, Marcel L. (De Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie, 2020-04-10)

Background For the management of drug-drug interactions (DDI), a risk-benefit assessment should be combined with the patient's perspective. Objective To investigate patients' and pharmacists' preferences regarding DDI ...
The association of irritable bowel complaints and perceived immune fitness among individuals that report impaired wound healing: Supportive evidence for the gut-brain-skin axis

Balikji, Jessica; Hoogbergen, Maarten M.; Garssen, Johan; Verster, Joris C. (PagePress Publications, 2021-11)

The gut–brain–skin axis is important in wound healing. The aim of this study was to investigate the association between experiencing irritable bowel syndrome (IBS) symptoms, perceived immune fitness, and impaired wound ...
A Chemically Defined Hydrogel for Human Liver Organoid Culture

Ye, Shicheng; Boeter, Jochem W.B.; Mihajlovic, Marko; van Steenbeek, Frank G.; van Wolferen, Monique E.; Oosterhoff, Loes A.; Marsee, Ary; Caiazzo, Massimiliano; van der Laan, Luc J.W.; Penning, Louis C.; Vermonden, Tina; Spee, Bart; Schneeberger, Kerstin (Wiley-VCH Verlag, 2020)

End-stage liver diseases are an increasing health burden, and liver transplantations are currently the only curative treatment option. Due to a lack of donor livers, alternative treatments are urgently needed. Human liver ...
Geneesmiddelverspilling verminderen

Bekker, C L; van den Bemt, B J F; Gardarsdottir, H; Egberts, A C G; Bouvy, M L (Bohn Stafleu Van Loghum bv, 2020)

Annually, in the Netherlands, at least 100 million euro is wasted on unused medication. This waste not only has considerable economic implications, but is also associated with an unnecessary burden on the environment and ...
Effect of mesenchymal stem cell-derived exosomes on the induction of mouse tolerogenic dendritic cells

Shahir, Mehri; Mahmoud Hashemi, Seyed; Asadirad, Ali; Varahram, Mohammad; Kazempour-Dizaji, Mehdi; Folkerts, Gert; Garssen, Johan; Adcock, Ian; Mortaz, Esmaeil (Wiley-Liss Inc., 2020-10)

Dendritic cells (DCs) orchestrate innate inflammatory responses and adaptive immunity through T-cell activation via direct cell–cell interactions and/or cytokine production. Tolerogenic DCs (tolDCs) help maintain immunological ...
Cost-utility and cost-effectiveness analysis of a clinical medication review focused on personal goals in older persons with polypharmacy compared to usual care: Economic evaluation of the DREAMeR study

Verdoorn, Sanne; van de Pol, Jeroen; Hövels, Anke M; Kwint, Henk-Frans; Blom, Jeanet W; Gussekloo, Jacobijn; Bouvy, Marcel L (NLM (Medline), 2021-02)

AIMS: The ageing society may lead to increasing healthcare expenditure. A clinical medication review (CMR) could potentially reduce costs. The aim of this study is to perform a cost-utility and cost-effectiveness analysis ...
Modeling of the luminal butyrate concentration to design an oral formulation capable of achieving a pharmaceutical response

Korsten, Sandra; Smits, Evelien A W; Garssen, Johan; Vromans, Herman (Elsevier Saunders, 2019-12)

Butyrate concentrations required for a direct effect on intestinal epithelial cells lie between 2–5 mM. In order for butyrate to affect the small intestine the local pharmacokinetics need to be understood. We used a ...
How does the general public balance convenience and cognitive pharmaceutical services in community pharmacy practice

van de Pol, Jeroen M; van Dijk, Liset; Koster, Ellen S; de Jong, Judith; Bouvy, Marcel L (Elsevier, 2021-03)

BACKGROUND: Community pharmacy is shifting its focus from traditional, product-focused roles to the provision of cognitive pharmaceutical services (CPS). Previous research has indicated that community pharmacists predominantly ...
Using pharmacy dispensing data to predict falls in older individuals

Gemmeke, Marle; Koster, Ellen S.; Pajouheshnia, Romin; Kruijtbosch, Martine; Taxis, Katja; Bouvy, Marcel L. (NLM (Medline), 2021-03)

Aims: Associations between individual medication use and falling in older individuals are well-documented. However, a comprehensive risk score that takes into account overall medication use and that can be used in daily ...
Complex coacervation-based loading and tunable release of a cationic protein from monodisperse glycosaminoglycan microgels

Schuurmans, Carl C L; Abbadessa, Anna; Bengtson, Mikkel A; Pletikapic, Galja; Eral, Huseyin Burak; Koenderink, Gijsje; Masereeuw, Rosalinde; Hennink, Wim E; Vermonden, Tina (The Royal Society of Chemistry, 2018)

Glycosaminoglycans (GAGs) are of interest for biomedical applications because of their ability to retain proteins (e.g. growth factors) involved in cell-to-cell signaling processes. In this study, the potential of GAG-based ...
Patiënten tevreden over contact apotheek tijdens coronacrisis

Koster, Ellen; Philbert, Daphne; Prins, Hetty; van Amerongen, Kees; Bouvy, Marcel (De Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie, 2022-01-14)

Patiënten zijn tevreden over de mogelijkheden om tijdens de coronacrisis contact te hebben met het apotheekteam. Ook heeft de pandemie weinig invloed op het geneesmiddelgebruik. Dit blijkt uit vragenlijstonderzoek onder ...
Correction to "Luminescent Gold Nanocluster-Decorated Polymeric Hybrid Particles with Assembly-Induced Emission"

Hembury, Mathew; Beztsinna, Nataliia; Asadi, Hamed; van den Dikkenberg, Joep B; Meeldijk, Johannes D; Hennink, Wim E; Vermonden, Tina (American Chemical Society : Division of Carbohydrate Chemistry, 2019)
Medicatie op rol voor de thuiswonende oudere patiënt

Mertens, Bram; Kwint, Henk Frans; Eekhof, Just; van Marum, Rob; Bouvy, Marcel (Bohn Stafleu van Loghum, 2021-01)

Zelfstandig wonende oudere patiënten vinden het vaak lastig om hun medicatie goed te beheren en te gebruiken. Vaak kampen ze met ordeningsproblemen. Als ondersteuning gebruiken veel van deze patiënten medicatie op rol. ...

Now showing items 8821-8840 of 95693