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Now showing items 8801-8820 of 95693

The pediatric acenocoumarol dosing algorithm: The Children Anticoagulation and Pharmacogenetics Study

Maagdenberg, Hedy; Bierings, Marc B; van Ommen, C Heleen; van der Meer, Felix J M; Appel, Inge M; Tamminga, Rienk Y J; Le Cessie, Saskia; Swen, Jesse J.; van der Straaten, Tahar; de Boer, Anthonius; Maitland-van der Zee, Anke H (Blackwell Publishing Ltd, 2018)

BACKGROUND: The large variability in dose requirement of vitamin K antagonists is well known. For warfarin, pediatric dosing algorithms have been developed to predict the right dose for a patient, however not for acenocoumarol. ...
Effects of age and genetic variations in VKORC1, CYP2C9 and CYP3A4 on the phenprocoumon dose in pediatric patients

Maagdenberg, Hedy; Bierings, Marc B.; Van Ommen, C. Heleen; Van Der Meer, Felix J.M.; Appel, Inge M.; Tamminga, Rienk Y.J.; Cessie, Saskia Le; Swen, Jesse J.; Van Der Straaten, Tahar; De Boer, Anthonius; Maitland-Van Der Zee, Anke H. (Future Medicine Ltd., 2018-10-01)

Aim: To study the effects of clinical and genetic factors on the phenprocoumon dose requirement in pediatric patients and to develop a dosing algorithm. Methods: Pediatric patients who used phenprocoumon were invited to ...
Quality of reporting of drug exposure in pharmacoepidemiological studies

Hempenius, Mirjam; Luijken, Kim; de Boer, Anthonius; Klungel, Olaf; Groenwold, Rolf; Gardarsdottir, Helga (John Wiley and Sons Ltd, 2020-09)

PURPOSE: Exposure definitions vary across pharmacoepidemiological studies. Therefore, transparent reporting of exposure definitions is important for interpretation of published study results. We aimed to assess the quality ...
Association of beta-blockers and first-registered heart rhythm in out-of-hospital cardiac arrest: real-world data from population-based cohorts across two European countries

Barcella, Carlo A; Eroglu, Talip E; Hulleman, Michiel; Granfeldt, Asger; Souverein, Patrick C; Mohr, Grimur H; Koster, Rudolph W; Wissenberg, Mads; de Boer, Anthonius; Torp-Pedersen, Christian; Folke, Fredrik; Blom, Marieke T; Gislason, Gunnar H; Tan, Hanno L (Oxford University Press, 2020-08)

AIMS: Conflicting results have been reported regarding the effect of beta-blockers on first-registered heart rhythm in out-of-hospital cardiac arrest (OHCA). We aimed to establish whether the use of beta-blockers influences ...
The development of a test battery to assess the hand-eye functions relevant in predicting easy and accurate tablet subdivision in older people: a pilot study

Riet-Nales, Diana A.; Donkerbroek, Linda; Nicia, Agnes; Oussoren, Christien; de Boer, Anthonius; van den Bemt, Bart (NLM (Medline), 2020-09-17)

AIM: Tablets may be subdivided for dose adaptations or to ease swallowing. The handling is common in older patients but can be difficult and inaccurate. Currently, it is not known which hand-eye functions are determining ...
Comparative effectiveness and safety of direct oral anticoagulants versus warfarin in UK patients with atrial fibrillation and type 2 diabetes: a retrospective cohort study

Rustem Gulluoglu, Fatma; Souverein, Patrick C; van den Ham, Hendrika A; de Boer, Anthonius; Komen, Joris (John Wiley and Sons Ltd, 2021)

PURPOSE: To estimate the effectiveness and safety of direct oral anticoagulants (DOACs) compared with warfarin in AF patients with type 2 diabetes (T2DM). METHODS: A retrospective cohort study was designed, using the UK ...
Sleep, eating disorder symptoms, and daytime functioning

Tromp, Marilou D P; Donners, Anouk A M T; Garssen, J.; Verster, J.C. (Dove Medical Press Ltd., 2016)

OBJECTIVE: To investigate the relationship between eating disorders, body mass index (BMI), sleep disorders, and daytime functioning. DESIGN: Survey. SETTING: The Netherlands. PARTICIPANTS: N=574 Dutch young adults (18-35 ...
Rivaroxaban was found to be noninferior to warfarin in routine clinical care: A retrospective noninferiority cohort replication study

Althunian, Turki A.; de Boer, Anthonius; Groenwold, Rolf H.H.; Rengerink, Katrien O.; Souverein, Patrick C.; Klungel, Olaf H. (John Wiley and Sons Ltd, 2020)

Purpose: To compare the effectiveness and safety of a drug in daily practice with the outcomes of a target non-inferiority trial by rigorously mimickingin an observational study the trial's design features. Methods: This ...
Opioid use is associated with increased out-of-hospital cardiac arrest risk among 40,000-cases across two countries

ESCAPE-NET Investigators (NLM (Medline), 2022)

AIMS: Opioid use has substantially increased in the last decade and is associated with overdose mortality, but also with increased mortality from cardiovascular causes. This finding may partly reflect an association between ...
Multiple categories of non-cardiac QT-prolonging drugs are associated with increased risk of out-of-hospital cardiac arrest: real-world data from a population-based study

Eroglu, Talip E; Blom, Marieke T; Souverein, Patrick C; de Boer, Anthonius; Tan, Hanno L (Oxford University Press, 2022)

AIM: Drugs causing QT-prolongation as off-target effect [non-cardiac QT-prolonging drugs (QT-drugs)] increase the risk of out-of-hospital cardiac arrest (OHCA). Such drugs are categorized in multiple clinically widely used ...
Out-of-hospital cardiac arrest and differential risk of cardiac and non-cardiac QT-prolonging drugs in 37 000 cases

for the ESCAPE-NET Investigators (NLM (Medline), 2022)

Aims: Drugs that prolong the QT interval, either by design (cardiac QT-prolonging drugs: anti-arrhythmics) or as off-target effect (non-cardiac QT-prolonging drugs), may increase the risk of ventricular arrhythmias and ...
Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells

Abdi, J; Garssen, J; Faber, J; Redegeld, F A (Elsevier, 2015)

The n-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been shown to enhance the effect of chemotherapeutic drugs in clinical studies in cancer patients and to induce apoptotic ...
A potential role for regulatory T-cells in the amelioration of DSS induced colitis by dietary non-digestible polysaccharides

Hartog, Anita; Belle, Fabiën N; Bastiaans, Jacqueline; de Graaff, Priscilla; Garssen, Johan; Harthoorn, Lucien F; Vos, Arjan P (Elsevier, 2015)

Inflammatory bowel diseases (IBD) including ulcerative colitis (UC) and Crohn's disease (CD) are chronic relapsing inflammatory disorders of the gastrointestinal tract. The interaction between a disturbed microbial ...
Mapping Porous Solid Catalysts with Fluorescent Molecules and Nanoparticles

Maris, Jacob Jan Erik (Universiteit Utrecht, 2023-06-07)

In this PhD thesis, fluorescent molecules or nanoparticles were investigated to probe the pore space of heterogeneous catalysts and mass transport therein. The fluorescent emitters (guests) report on the properties of the ...
Medication adherence in adolescents in current practice: Community pharmacy staff's opinions

Koster, Ellen S.; Philbert, Daphne; Winters, Nina A.; Bouvy, Marcel L. (Pharmaceutical Press, 2015-06-01)

Objective To explore pharmacy staff's perspectives regarding medication use behaviour in adolescent patients. Methods Structured face-to-face interviews were conducted with 170 community pharmacy staff members. Key findings ...
Patient-provider communication about medication use at the community pharmacy counter

Van Dijk, M; Blom, Lyda; Koopman, Laura; Philbert, Daphne; Koster, Ellen; Bouvy, Marcel; van Dijk, Liset (Pharmaceutical Press, 2016-02-01)

Objective: The objectives of this study were to, first, describe the information exchanged between pharmacy staff and patients about prescribed medication at the community pharmacy counter, and second, to investigate to ...
STOPP-START-criteria kunnen medicatiebeoordeling niet vervangen

Verdoorn, Sanne; Kwint, Henk Frans; Faber, Adrianne; Gussekloo, Jacobijn; Bouvy, Marcel (Bohn Stafleu van Loghum, 2016-01-01)

Achtergrond De STOPP- en START-criteria zijn opgesteld om ten onrechte gebruikte en ten onrechte achterwege gebleven medicatie bij ouderen op te sporen. Of daarmee alle farmacotherapiegerelateerde problemen (FTP’s) kunnen ...
Stakeholders' views on and their minimal requirements for redispensing unused medicines: A qualitative study

Bekker, C.; Gardarsdottir, H.; Egberts, A.; Bouvy, M.; Van Den Bemt, B. (Springer, 2016-01-01)

Background and objective: Medication wastage has undesirable consequences both economic and environmental. Wastage is partly unavoidable, but could be reduced by redispensing unused medicines that are returned to the ...
Medisch-farmaceutische beslisregels en nierfunctiemeting in de openbare apotheek: wat levert het op?

Heringa, M.; Van De Steeg-Van Gompel, Caroline H P A; Bouvy, M.L. (De Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie, 2017-01-19)

OBJECTIVE To investigate the frequency and management of drug therapy alerts about drug use in patients with (potential) renal impairment, to investigate the contribution of point-of-care testing (PoCT) of renal function ...
Adolescents’ Perspectives on Atopic Dermatitis Treatment: Experiences, Preferences, and Beliefs

Kosse, R.C.; Bouvy, M.L.; Daanen, Maud; De Vries, Tjalling W.; Koster, E.S. (American Medical Association, 2018)

IMPORTANCE For a considerable proportion of pediatric patients, atopic dermatitis symptoms persist into adolescence. Previous studies have focused mainly on (parents of) children, whereas little is known about adolescents ...

Now showing items 8801-8820 of 95693