Recently added

DSpace/Manakin Repository

Utrecht University Repository: Recent submissions

  • Vemurafenib Inhibits Acute and Chronic Enterovirus Infection by Affecting Cellular Kinase Phosphatidylinositol 4-Kinase Type IIIb 
    Laajala, Mira; Zwaagstra, Marleen; Martikainen, Mari; Nekoua, Magloire Pandoua; Benkahla, Mehdi; Sane, Famara; Gervais, Emily; Campagnola, Grace; Honkimaa, Anni; Sioofy-Khojine, Amir-Babak; Hyöty, Heikki; Ojha, Ravi; Bailliot, Marie; Balistreri, Giuseppe; Peersen, Olve; Hober, Didier; Van Kuppeveld, Frank; Marjomäki, Varpu (American Society for Microbiology, 2023-08-17)
    Enteroviruses are one of the most abundant viruses causing mild to serious acute infections in humans and also contributing to chronic diseases like type 1 diabetes. Presently, there are no approved antiviral drugs against ...
  • Elucidating the Structure and Composition of Individual Bimetallic Nanoparticles in Supported Catalysts by Atom Probe Tomography 
    Zand, Florian; Hangx, Suzanne J.T.; Spiers, Christopher J.; van den Brink, Peter J.; Burns, James; Boebinger, Matthew G.; Poplawsky, Jonathan D.; Monai, Matteo; Weckhuysen, Bert M. (American Chemical Society, 2023-08-09)
    Understanding and controlling the structure and composition of nanoparticles in supported metal catalysts are crucial to improve chemical processes. For this, atom probe tomography (APT) is a unique tool, as it allows for ...
  • A pain in the neck: Articular process joint osteochondrosis and intervertebral disc degeneration in warmblood horses 
    Bergmann, Wilhelmina (Utrecht University, 2023-09-14)
    Cervical vertebral stenotic myelopathy (CVM) is a well-known syndrome in horses in which compression of the spinal cord and nerves in the neck leads to nervous signs. In warmblood horses, osteoarthrosis of the articular ...
  • A small assemblage of early Oligocene rodents and insectivores from the Sivas basin, Turkey 
    van de Weerd, Andrew A.; de Bruijn, Hans; Wessels, Wilma (Springer, 2023-09)
    The assemblage of small mammals from a site near Yeniköy (Anatolia) is described. The assemblage was collected by screen-washing a sample from a locality in the Selimye Formation (Sivas basin). The site has a magneto-stratigraphic ...
  • Cell-type-specific transcriptomics reveals that root hairs and endodermal barriers play important roles in beneficial plant-rhizobacterium interactions 
    Verbon, Eline H.; Liberman, Louisa M.; Zhou, Jiayu; Yin, Jie; Pieterse, Corné M.J.; Benfey, Philip N.; Stringlis, Ioannis A.; de Jonge, Ronnie (Cell Press, 2023-07-03)
    Growth- and health-promoting bacteria can boost crop productivity in a sustainable way. Pseudomonas simiae WCS417 is such a bacterium that efficiently colonizes roots, modifies the architecture of the root system to increase ...
  • The conserved iol gene cluster in Pseudomonas is involved in rhizosphere competence 
    Sánchez-Gil, Juan J; Poppeliers, Sanne W M; Vacheron, Jordan; Zhang, Hao; Odijk, Bart; Keel, Christoph; de Jonge, Ronnie (Cell Press, 2023-08-07)
    The Pseudomonas genus has shown great potential as a sustainable solution to support agriculture through its plant-growth-promoting and biocontrol activities. However, their efficacy as bioinoculants is limited by unpredictable ...
  • Growth rate is a dominant factor predicting the rhizosphere effect 
    López, José L.; Fourie, Arista; Poppeliers, Sanne W.M.; Pappas, Nikolaos; Sánchez-Gil, Juan J.; de Jonge, Ronnie; Dutilh, Bas E. (Nature Publishing Group, 2023-09)
    The root microbiome is shaped by plant root activity, which selects specific microbial taxa from the surrounding soil. This influence on the microorganisms and soil chemistry in the immediate vicinity of the roots has been ...
  • Seed tuber imprinting shapes the next-generation potato microbiome 
    Song, Yang; Spooren, Jelle; Jongekrijg, Casper D; Manders, Ellen HH; de Jonge, Ronnie; Pieterse, Corne MJ; Bakker, Peter AHM; Berendsen, Roeland L (bioRxiv, 2023-07-27)
    Potato seed tubers are colonized and inhabited by soil-borne microbes, some of which can positively or negatively impact the performance of the emerging daughter plant in the next season. In this study, we investigated the ...
  • Molecular and evolutionary basis of O-antigenic polysaccharide driven phage sensitivity in environmental pseudomonads 
    Vacheron, Jordan; Heiman, Clara Margot; Garneau, Julian R; Kupferschmied, Peter; de Jonge, Ronnie; Garrido-Sanz, Daniel; Keel, Christoph (bioRxiv, 2023-05-15)
    Pseudomonas protegens CHA0, a bacterial strain able to suppress plant pathogens as well as efficiently kill lepidopteran pest insects, has been studied as biocontrol agent to prevent ensuing agricultural damage. However, ...
  • Echolocating whales and bats express the motor protein prestin in the inner ear: a potential marker for hearing loss 
    Morell, Maria; Vogl, Wayne; IJsseldijk, L.L.; Piscitelli-Doshkov, Marina; Tong, Ling; Ostertag, Sonja; Ferreira, Marisa; Fraija-Fernandez, Natalia; Colegrove, Kathleen M.; Puel, Jean-Luc; Raverty, Stephen; Shadwick, Robert E. (Frontiers Media S.A., 2020)
    Prestin is an integral membrane motor protein located in outer hair cells of the mammalian cochlea. It is responsible for electromotility and required for cochlear amplification. Although prestin works in a cycle-by-cycle ...
  • Re-evaluation of pachycormid fishes from the Late Jurassic of Southwestern Germany 
    Maxwell, Erin; Lambers, Paul; Lopez-Arbarello, Adriana; Schweigert, Guenter (Instytut Paleobiologii PAN, 2020-08-19)
    Pachycormidae is an extinct group of Mesozoic fishes that exhibits extensive body size and shape disparity. The Late Jurassic record of the group is dominated by fossils from the lithographic limestone of Bavaria, Germany ...
  • Scythes, sickles and other blades: Defining the diversity of pectoral fin morphotypes in Pachycormiformes 
    Liston, Jeff J.; Maltese, Anthony E.; Lambers, Paul H.; Delsate, Dominique; Harcourt-Smith, William E.H.; Van Heteren, Anneke H. (PeerJ, 2019-11-07)
    The traditional terminology of 'scythe' or 'sickle' shaped is observed to be flawed as an effective descriptor for pectoral fin shape in pachycormids. The diversity of pachycormid pectoral fin shapes is assessed across the ...
  • Exploring oxygen dynamics and depletion in an intensive bivalve production area in the coastal sea off Rushan Bay, China 
    Wu, Wentao; Liu, Jun; Bouwman, Alexander F.; Wang, Junjie; Yin, Xunqiang; Zang, Jiaye; Ran, Xiangbin (Inter-Research, 2020-09-10)
    Hypoxia is a mounting problem affecting the world’s coastal waters, with severe consequences for marine ecosystems. Coastal oxygen consumption has been increasing, mainly owing to the continued spread nutrient discharges. ...
  • Harmful Algal Blooms in Chinese Coastal Waters Will Persist Due to Perturbed Nutrient Ratios 
    Wang, Junjie; Bouwman, Alexander F.; Liu, Xiaochen; Beusen, Arthur H.W.; Van Dingenen, Rita; Dentener, Frank; Yao, Yulong; Glibert, Patricia M.; Ran, Xiangbin; Yao, Qingzhen; Xu, Bochao; Yu, Renchen; Middelburg, Jack J.; Yu, Zhigang (American Chemical Society, 2021-03-09)
    The three large marine ecosystems (LMEs) bordering China (Yellow Sea/Bohai Sea, East China Sea, and South China Sea) have received excess nitrogen (N) and phosphorus (P) in the past decades with detrimental consequences ...
  • Towards Space Efficient Two-Point Shortest Path Queries in a Polygonal Domain 
    Berg, Sarita de; Miltzow, Tillmann; Staals, Frank (arXiv, 2023-03-01)
    We devise a data structure that can answer shortest path queries for two query points in a polygonal domain P on n vertices. For any ε>0, the space complexity of the data structure is O(n10+ε) and queries can be answered ...
  • The Complexity of Recognizing Geometric Hypergraphs 
    Bertschinger, Daniel; Maalouly, Nicolas El; Kleist, Linda; Miltzow, Tillmann; Weber, Simon (arXiv, 2023-02-27)
    As set systems, hypergraphs are omnipresent and have various representations. In a geometric representation of a hypergraph H=(V,E), each vertex v∈V is a associated with a point pv∈Rd and each hyperedge e∈E is associated ...
  • Representing Matroids over the Reals is existsR-complete 
    Kim, Eunjung; Mesmay, Arnaud de; Miltzow, Tillmann (arXiv, 2023-01-09)
    A matroid M is an ordered pair (E,I), where E is a finite set called the ground set and a collection I⊂2E called the independent sets which satisfy the conditions: (I1) ∅∈I, (I2) I′⊂I∈I implies I′∈I, and (I3) I1,I2∈I and ...
  • Geometric Embeddability of Complexes Is ∃R-Complete 
    Abrahamsen, Mikkel; Kleist, Linda; Miltzow, Tillmann (Schloss Dagstuhl – Leibniz-Zentrum für Informatik GmbHSchloss Dagstuhl - Leibniz-Zentrum für Informatik, 2023-06-01)
    We show that the decision problem of determining whether a given (abstract simplicial) k-complex has a geometric embedding in Rd is complete for the Existential Theory of the Reals for all d ≥ 3 and k ∈ {d− 1, d}. Consequently, ...
  • Completeness for the Complexity Class ∀ ∃ R and Area-Universality 
    Dobbins, Michael Gene; Kleist, Linda; Miltzow, Tillmann; Rzazewski, Pawel (Springer New York, 2023-07)
    Exhibiting a deep connection between purely geometric problems and real algebra, the complexity class ∃R plays a crucial role in the study of geometric problems. Sometimes ∃R is referred to as the ‘real analog’ of NP. While ...
  • The Effect of Simple Emotional Gesturing in a Socially Assistive Robot on Child's Engagement at a Group Vaccination Day 
    Neerincx, Anouk; Leven, Jessica; Wolfert, Pieter; De Graaf, Maartje M.A. (Association for Computing Machinery (ACM), 2023-03-13)
    Children encounter high levels of stress and anxiety before receiving medical treatment, such as a vaccination. This paper explores the efect of emotional gesturing in socially assistive robots (SARs) on children's observed ...