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Now showing items 5341-5360 of 95693

De novo antibody sequencing based on mass spectrometry

Peng, Weiwei (2024-02-26)

Although the importance of antibodies in immunity was proposed more than one hundred years ago, comprehensively studying and characterizing antibodies remains a challenge. This thesis demonstrates how mass spectrometry ...
Synthesis and Functional Characterization of Novel Chimeric Vaccine Adjuvants & Chemo-Enzymatic Approaches to Synthesize Heparan Sulfate Oligosaccharides

Zhang, Liangwei (Utrecht University, 2024-02-23)

The work described in this thesis focuses on the development of novel chimeric vaccine adjuvants and the development of novel controlled chemo-enzymatic methods to synthesize a diverse library of heparan sulfate oligosaccharides ...
The Bacterial Cell Envelope: Specific Labeling and Its Applications

Xu, Yang (Utrecht University, 2024-02-26)

Although there has been significant progress in the understanding of the mechanism and regulation of bacterial cell envelope biogenesis, further exploration is required to fully understand the bacterial cell envelope and ...
Body image in eating disorders: Integrating aesthetic and functional body experience

Rekkers, Martha Elisabeth (Utrecht University, 2024-02-16)

The aim of this thesis was to extend knowledge related to assessment and treatment of negative body experience in eating disorders (EDs), with an emphasis on the role of body functionality in reducing body dissatisfaction. ...
Air pollution from livestock farms and respiratory health impacts in neighboring residents

Kersen, Warner van (Utrecht University, 2024-02-15)

Living close to livestock farms is known to pose respiratory health risks. In the densely populated and livestock-rich Netherlands, the VGO project investigated the health impacts on people living near animal farms. Previous ...
Mystifying Photoluminescence Mechanisms: Unraveling and exploiting non-ideal behavior of luminescent nanomaterials

Mangnus, Mark Joris Jeroen (Utrecht University, 2024-02-14)

Developing quantum dots (QDs) for applications in future devices is a challenge on several frontiers. Control over particle sizes and shapes is essential, but rational design of next-generation QDs also requires a deep ...
Repetition sans Ennui: Human and Algorithmic Discovery of Patterns in Music

Ren, Iris Yuping (Utrecht University, 2024-02-12)

Finding patterns is a common act in human intellectual endeavours, and it is a complex challenge tackled by both humans and algorithms. For several decades, musical pattern discovery algorithms have been researched, and ...
Deciphering acclimation strategies to combined abiotic stresses in Arabidopsis thaliana: a functional genomics approach

Jiang, Zhang (Utrecht University, 2024-02-12)

Plants grown in natural or agricultural environments are frequently exposed to abiotic stress and their combinations. Research on plant stress resilience usually focusses on single environmental stressors mostly imposed ...
E-cycling to work: Incentivizing behavioral change and the road to well-being

Kruijf, Willem Johan de (Utrecht University, 2024-02-09)

This research focuses on the effects of an e-cycling incentive program on short- and longer-term behavioral changes, and how these outcomes be understood from underlying behavioral processes and external factors. The ...
Women, work and colonialism in the Netherlands and Java: comparisons, contrasts and connections, 1830-1940

Nederveen Meerkerk, Elise van (Palgrave Macmillan, 2019)

Recent postcolonial studies have stressed the importance of the mutual influences of colonialism on both colony and metropole. This book studies such colonial entanglements and their effects by focusing on developments in ...
Challenging the de-industrialization thesis: Gender and indigenous textile production in Java under Dutch colonial rule, c. 1830–1920

Nederveen Meerkerk, Elise van (2017-11)

Many dependency theorists as well as economic historians have contended that nineteenth-century imperial policies and economic globalization de-industrialized the global ‘periphery’. European metropoles extracted raw ...
Socioeconomic (dis)continuity across generations: The role of adolescent behavioral control and social competence

Fakkel, Matthijs (Utrecht University, 2024-02-07)

Relatively little is known about which individual competencies help determine if adolescents experience social reproduction or social mobility. Consequently, it remains a challenge to identify effective policies that improve ...
Pharmaceutical formulations for poorly water-soluble drugs: From technology to solutions for clinical use

Rooimans, Thijs (Utrecht University, 2024-02-07)

The thesis, titled 'Pharmaceutical formulations for poorly water-soluble drugs - From technology to solutions for clinical use' explores various formulation strategies to improve the water solubility of poorly water-soluble ...
Tiny Messengers in the Milky Universe: The Secrets of Human Milk Extracellular Vesicles

Giovanazzi, Alberta (Utrecht University, 2024-02-07)

After birth, the mother-infant dyad switches from aseptic transfer of nutrients through the umbilicus to dependence on milk. During early-life it is crucial that neonate immune system learns to tolerate harmless food and ...
Fundamental physics with gravitational waves: Testing general relativity and studying neutron stars with current and future detectors

Puecher, Anna (Utrecht University, 2024-02-07)

Since their prediction in Einstein’s theory of general relativity, gravitational waves took a hundred years to be actually detected. Nevertheless, the wait was well rewarded since measuring gravitational waves did not only ...
Fc glycosylation of alloantibodies in platelet refractoriness

Osch, Thijs Luc Junior van (Utrecht University, 2024-02-06)

Platelet transfusions are essential for the prevention and treatment of hemorrhagic complications in patients with platelet dysfunction or thrombocytopenia. However, patients requiring frequent platelet transfusions are ...
Nurturing networks: A Social Movement lens on Community-Supported Agriculture

Guerrero Lara, Leonie (Utrecht University, 2024-01-31)

The political dimension of community-supported agriculture (CSA), beyond prefiguring alternatives to the conventional, capitalist agri-food system, has remained largely unexplored by the scientific community. The large ...
Uncovering The Potential of Proximal Tubule Cells for Disease Modeling and Therapeutic Interventions

Ferreira Faria, João Pedro (Utrecht University, 2024-01-05)

This thesis focused on uncovering the intricate interactions between the proximal tubule (PT) and disease mediators through the development and application of in vitro models. For this, we extensively reviewed the currently ...
Global goalsetting as a policy response: The impact of the Sustainable Development Goals on International Organizations

Driel, Melanie van (Utrecht University, 2024-02-02)

Global governance is highly fragmented, characterized by tens of thousands of international organizations, treaties and regimes with specialized mandates. By agreeing on the Sustainable Development Goals (SDGs) in 2015, ...
Diverse Stepfamilies: Parenting and Children's Well-being

Arat, Ece (Utrecht University, 2024-02-02)

This dissertation focuses on the growing diversity of stepfamilies in the Netherlands. While in the past, married stepfather families in which mothers had children's sole physical custody were most dominant, this pattern ...

Now showing items 5341-5360 of 95693