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Utrecht University Repository: Recent submissions

  • Entrepreneurial Ecosystems for the Africa we want 
    Nkontwana, Phumlani; Stam, Erik (Utrecht UniversityUtrecht University, 2023-06)
    Many regions and countries aim to copy a Silicon Valley model of entrepreneurship-led development. We argue that this is misguided, in general, and in low income economies even more. We advocate an alternative approach ...
  • Materials Selection in Economic Modeling 
    Boumans, Marcel (Utrecht UniversityUtrecht University, 2023-04)
    Templates travel because they offer a tractable format that can be used for model-building in a variety of domains. It is often because of this quality that a particular template is chosen. But one cannot assume that there ...
  • Shared of a Socialist Legacy?: Innovation Activity in East and West Germany 1877-2014 
    Fritsch, Michael; Greve, Maria; Wyrwich, Michael (Utrecht UniversityUtrecht University, 2023-02)
    The unification of the East and West German states in 1990 initiated the integration of two distinct innovation systems. In this process, the poorly functioning socialist system of East Germany adopted the formal institutions ...
  • Organizational adaptiveness during COVID-19: The role of absorptive capacity and management practices 
    Groenewegen, Jesse; Hardeman, Sjoerd; Stam, Erik (U.S.E. Research Institute, 2023-02)
    COVID-19 forced many businesses to rapidly adapt to new circumstances. While firms could not foresee this shock, some were better able to adapt than others. This required firms to quickly and efficiently process new ...
  • Between-Word Processing and Text-Level Skills Contributing to Fluent Reading of (Non)Word Lists and Text 
    van Viersen, Sietske; Altani, Angeliki; de Jong, Peter F.; Protopapas, Athanassios (Research SquareSpringer Netherlands, 2023-10-01)
    This study investigated (1) sequential (between-word) processing efficiency at various points during development, (2) its importance within a range of measures typically used to assess reading fluency, and 3) how subskills ...
  • A palmitoyl transferase chemical genetic system to map ZDHHC-specific S-acylation 
    Ocasio, Cory A.; Baggelaar, Marc; Sipthorp, James; Losada de la Lastra, Ana; Volarić, Jana; Soudy, Christelle; Storck, Elisabeth M.; Palma-Duran, Susana A.; MacRae, James I.; Tomic, Goran; Carr, Lotte; Downward, Julian; S. Eggert, Ulrike; Tate, Edward W. (bioRxivCold Spring Harbor Laboratory, 2023-04-18)
    The 23 human ZDHHC S-acyltransferases catalyze long-chain S-acylation at cysteine residues across an extensive network of hundreds of proteins important for normal physiology or dysregulated in disease. Here we present a ...
  • Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis 
    Tomic, Goran; Refermat, Alice Y.; Sheridan, Clare; Baggelaar, Marc; Sipthorp, James; Sudarshan, Bhuvana; Ocasio, Cory A.; Suárez-Bonnet, Alejandro; Priestnall , Simon L.; Herbert, Eleanor; Tate, Edward W.; Downward, Julian (bioRxivCold Spring Harbor Laboratory, 2023-02-08)
    Metastasis is one of the defining features of pancreatic ductal adenocarcinoma (PDAC) that contributes to poor prognosis. In this study, the palmitoyl transferase ZDHHC20 was identified in an in vivo shRNA screen as critical ...
  • Visualization of translation reorganization upon persistent collision stress in mammalian cells 
    Fedry, Juliette; Silva, Joana; Vanevic, Mihajlo; Fronik, Stanley; Mechulam, Yves; Schmitt, Emmanuelle; des Georges, Amédée; Faller, William; Förster, Friedrich (bioRxivCold Spring Harbor Laboratory, 2023-03-24)
    UNLABELLED: Aberrantly slow mRNA translation leads to ribosome stalling and subsequent collision with the trailing neighbor. Ribosome collisions have recently been shown to act as stress sensors in the cell, with the ability ...
  • Full-waveform tomography reveals iron spin crossover in Earth lower mantle 
    Cobden, Laura; Zhuang, Jingyi; Lei, Wenjie; Wentzcovitch, Renata; Trampert, Jeannot; Tromp, Jeroen (arXiv, 2023-03-09)
    Joint interpretation of bulk and shear wave speeds constrains the chemistry of the deep mantle. At all depths, the diversity of wave speeds cannot be explained by an isochemical mantle. Between 1000 and 2500 km depth, ...
  • Media Literacy Education for Diverse Societies 
    Neag, Annamariá; Bozdag, Cigdem; Leurs, Koen (OSFPREPRINTS, 2021-10-28)
    Since the 1980s, media literacy became a central topic in the field of communication, media and education studies, as a result of a parallel growth of polarization between societal groups and use of digital technologies ...
  • Gebakken lucht – Identifying Illicit Financial Flows of Oil and Gas Corporations from Africa through the Netherlands 
    Brom, Denise; de Gruijter, Dorian; Ferwerda, Joras; Unger, Brigitte (TU WienTU Wien, 2023)
    ‘Gebakken lucht’ is a Dutch expression that literally means “baked air”, proverbially referring to something that appears like quite something, while it is in fact nothing. Oil and gas corporations that delve valuable ...
  • Instance complexity of Boolean functions 
    Liu, Alison; Mande, Nikhil S. (arXiv, 2023-09-26)
    In the area of query complexity of Boolean functions, the most widely studied cost measure of an algorithm is the worst-case number of queries made by it on an input. Motivated by the most natural cost measure studied in ...
  • Optogenetic control of kinesins -1, -2, -3 and dynein reveals their specific roles in vesicular transport 
    Nagpal, Sahil; Wang, Samuel; Swaminathan, Karthikeyan; Berger, Florian; Hendricks, Adam (bioRxiv, 2023-04-19)
    Each cargo in a cell employs a unique set of motor proteins for its transport. Often multiple types of kinesins are bound to the same cargo. It is puzzling why several types of motors are required for robust transport. To ...
  • Homeostatic relevance promotes access to visual awareness 
    Litwin, Piotr; Motyka, Paweł Albert; Gayet, Surya (OSFPREPRINTS, 2023-03-15)
    Fear and disgust have been associated with opposite influences on visual processing, even though both constitute negative homeostatic emotions that motivate avoidance behavior and entail increased arousal. In the current ...
  • Microstructured silk-fiber scaffolds with enhanced stretchability 
    Viola, Martina; Cedillo-Servin, Gerardo; van Genderen, Anne Metje; Imhof, Isabella; Vena, Paula; Mihajlovic, Marko; Piluso, Susanna; Malda, Jos; Vermonden, Tina; Castilho, Miguel (bioRxivCold Spring Harbor Laboratory, 2023-06-01)
    Despite extensive research, current methods for creating three-dimensional (3D) silk fibroin (SF) scaffolds lack control over molecular rearrangement, particularly in the formation of β-sheet nanocrystals, as well as ...
  • Latent Memory Traces for Prospective Items in Visual Working Memory 
    Luzi, Xu; Sahakian, Andre; Gayet, Surya; Paffen, Chris; Stigchel, Stefan van der (PsyArXiv, 2023-08-21)
    Visual working memory is a capacity-limited cognitive system that is utilized for enabling goal-directed actions. When sampling items for visual working memory storage, however, observers are often exposed to other items ...
  • Genipin Crosslinks the Extracellular Matrix to Rescue Developmental and Degenerative Defects, and Accelerates Regeneration of Peripheral Neurons 
    Saito-Diaz, Kenyi; Dietrich, Paula; Wu, Hsueh-Fu; Sun, Xin; Jayesh Patel, Archie; Gale Wzientek, Camryn; Robert Prudden, Anthony; Boons, Geert-Jan; Chen, Shuibing; Studer, Lorenz; Xu, Bingqian; Dragatsis, Ioannis; Zeltner, Nadja (bioRxivCold Spring Harbor Laboratory, 2023-03-24)
    UNLABELLED: The peripheral nervous system (PNS) is essential for proper body function. A high percentage of the population suffer nerve degeneration or peripheral damage. For example, over 40% of patients with diabetes or ...
  • Statistical Learning Facilitates Access to Awareness 
    Xu, Luzi; Paffen, Chris; Stigchel, Stefan van der; Gayet, Surya (OSFPREPRINTS, 2023-11-01)
    Statistical learning (SL) allows us to quickly extract regularities from sensory inputs. Although many studies have established that SL serves a wide range of cognitive functions, it remains unknown whether SL impacts ...
  • Local structural flexibility drives oligomorphism in computationally designed protein assemblies 
    Khmelinskaia, Alena; Bethel, Neville P; Fatehi, Farzad; Antanasijevic, Aleksandar; Borst, Andrew J; Lai, Szu-Hsueh; Wang, Jing Yang John; Mallik, Bhoomika Basu; Miranda, Marcos C; Watkins, Andrew M; Ogohara, Cassandra; Caldwell, Shane; Wu, Mengyu; Heck, Albert J R; Veesler, David; Ward, Andrew B; Baker, David; Twarock, Reidun; King, Neil P (bioRxiv, 2023-10-19)
    Many naturally occurring protein assemblies have dynamic structures that allow them to perform specialized functions. For example, clathrin coats adopt a wide variety of architectures to adapt to vesicular cargos of various ...
  • Cholangiocyte Organoids to Model Chlorpromazine-Induced Bile Duct Injury 
    Wang, Zhenguo; Xing, Chen; Laan, Luc J.W. van der; Verstegen, Monique M.A.; Spee, Bart; Masereeuw, Rosalinde (Research Square, 2023-10-23)
    Background Drug induced bile duct injury is a frequently observed clinical problem leading to a wide range of pathological features. During the past decades, several agents have been identified with various postulated ...