Abstract
Surprisingly, immunosuppressive treatment can
enhance the efficacy of conventional HIV-1 antiretroviral
treatment, and can be beneficial for HIV-1-
infected patients. This argues for a role of target cell
availability in limiting the HIV-1 infection, and is in
agreement with mathematical models suggesting that
immunosuppression may limit the outgrowth of drugresistant
escape mutants. Immunosuppressive drugs like
hydroxyurea (HU) may
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