Abstract
Dimethylamino- and dimethylaminomethyl-substituted diarylacetylenes were prepared by the Pd(PPh{3}){4}-catalyzed coupling reaction of dimethylamino- and dimethylaminomethyl-substituted aryl halides with arylacetylenes.Reaction of the asymmetric diarylacetylenes with methylmagnesium bromide in the presence of NiCl{2}(PPh{3}){2} gave stereo- and regio-selectively cis addition products in which the aryl group bearing the built-in ligand (Me{2}N or Me{2}NCH{2})
... read more