Lymph Node Staging and Treatment in Pediatric Patients With Soft Tissue Sarcomas: A Consensus Opinion from the Children's Oncology Group, European paediatric Soft tissue sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe
Terwisscha van Scheltinga, Sheila; Schoot, Reineke A.; Routh, Jonathan C.; Seitz, Guido; Kao, Simon C.; de Keizer, Bart; Shulkin, Barry; Ewijk, Roelof van; McCarville, Beth; Casey, Dana; Allen-Rhoades, Wendy; Mercolini, Federico; Merks, Hans; Orbach, Daniel; Kapadia, Tejas; Walterhouse, David O.; Davila Fajardo, Raquel; Hiemcke-Jiwa, Laura; Franzius, Christiane; De Corti, Federica; Tang, Vivian; Metts, Jonathan; Oberoi, Saphna; Vokuhl, Christian; Dasgupta, Roshni; Birz, Suzi; Rodeberg, David
(2025) Pediatric Blood and Cancer, volume 72, issue 4
(Article)
Abstract
Accurate staging of nodal involvement in pediatric sarcoma patients is important to determine correct systemic and local therapy, with the goal to reduce subsequent recurrences. However, differences in lymph node staging strategies, definitions, and treatment protocols between the Children's Oncology Group (COG), European paediatric Soft tissue sarcoma Study Group (EpSSG),
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and the Cooperative Weichteilsarkom Studiengruppe (CWS) complicate comparisons. In this article, we aim to establish internationally recognized recommendations for lymph node assessment and treatment of children and adolescents diagnosed with rhabdomyosarcoma (RMS) and non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) according to the Consensus Conference Standard Operating Procedure methodology.
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Keywords: including soft tissue, non-rhabdoid, pediatric oncology, rhabdomyosarcoma, sarcomas, Pediatrics, Perinatology, and Child Health, Hematology, Oncology, Journal Article
ISSN: 1545-5009
Publisher: Wiley-Liss Inc.
Note: Publisher Copyright: © 2025 Wiley Periodicals LLC.
(Peer reviewed)