Decay Rates of Maternal Tetanus, Diphtheria, and Pertussis Antibody Levels in Early and Moderate-to-Late Preterm and Term Infants at Birth and at Two Months

Immink, Maarten M; van der Maas, Nicoline A T; Bekker, Mireille N; de Melker, Hester E; den Hartog, Gerco; Rots, Nynke Y; van Gageldonk, Pieter G M; Groenendaal, Floris; Sanders, Elisabeth A M

doi:https://doi.org/10.1093/ofid/ofae717

Decay Rates of Maternal Tetanus, Diphtheria, and Pertussis Antibody Levels in Early and Moderate-to-Late Preterm and Term Infants at Birth and at Two Months

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Decay Rates of Maternal Tetanus, Diphtheria, and Pertussis Antibody Levels in Early and Moderate-to-Late Preterm and Term Infants at Birth and at Two Months

Immink, Maarten M; van der Maas, Nicoline A T; Bekker, Mireille N; de Melker, Hester E; den Hartog, Gerco; Rots, Nynke Y; van Gageldonk, Pieter G M; Groenendaal, Floris; Sanders, Elisabeth A M

(2025) Open Forum Infectious Diseases, volume 12, issue 1

(Article)

Abstract

A post hoc analysis of maternally derived antibodies at birth and age 2 months following second trimester maternal Tdap vaccination between 20 and 24 weeks' gestational age (GA) showed a faster decay rate of Tdap-related immunoglobulin G in early preterms born before 32 weeks' GA compared with moderate-to-late preterms and ... read more

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Keywords: antibody decay, full-term, immunogenicity, maternal immunization, pertussis, preterm, Oncology, Infectious Diseases

DOI: https://doi.org/10.1093/ofid/ofae717

ISSN: 2328-8957

Publisher: Oxford University Press

(Peer reviewed)