Humidification of incubator air for premature infants: An empty systematic review

Abstract

Background: During the first days or weeks, humidified incubators are used for preterm infants. Transepidermal water loss is then at its highest level. There is no consensus on the optimal level or the duration of humidification for preterm infants below 32 weeks GA. Objective: This study aimed to review the effects of low humidity versus moderate or high humidity levels, as well as studies investigating the impact of short versus moderate to long durations of humidity exposure. Methods/search strategy: Randomized control trials, cohort studies, pre-posttest, and case-control studies were included. Search was performed in PubMed, Cochrane Library, Ovid Emcare, Web of Science and Embase. The selected studies were graded using the Joanna Briggs critical appraisal tool. Findings: No studies met the inclusion criteria; therefore, this is an empty systematic review. Conclusion: The absence of evidence regarding optimal incubator humidity emphasized the need for solid research to improve outcomes for preterm infants.