Developing technologies to assess vascular ageing: a roadmap from VascAgeNet
Zanelli, Serena; Agnoletti, Davide; Alastruey, Jordi; Allen, John; Bianchini, Elisabetta; Bikia, Vasiliki; Boutouyrie, Pierre; Bruno, Rosa Maria; Climie, Rachel; Djamaleddine, Djeldjli; Gkaliagkousi, Eugenia; Giudici, Alessandro; Gopcevic, Kristina; Grillo, Andrea; Guala, Andrea; Hametner, Bernhard; Joseph, Jayaraj; Karimpour, Parmis; Kodithuwakku, Vimarsha; Kyriacou, Panayiotis A; Lazaridis, Antonios; Lonnebakken, Mai Tone; Martina, Maria Raffaella; Mayer, Christopher Clemens; Nabeel, P M; Navickas, Petras; Nemcsik, Janos; Orter, Stefan; Park, Chloe; Pereira, Telmo; Pucci, Giacomo; Amado Rey, Ana Belen; Salvi, Paolo; Gonçalves Seabra, Ana Carolina; Seeland, Ute; van Sloten, Thomas; Spronck, Bart; Stansby, Gerard; Steens, Indra; Stieglitz, Thomas; Tan, Isabella; Veerasingam, Dave; Wassertheurer, Siegfried; Weber, Thomas; Westerhof, Berend E; Charlton, Peter H
(2024) Physiological Measurement, volume 45, issue 12
(Article)
Abstract
Vascular ageing (vascular ageing) is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular risk, with potential applications in disease diagnosis and prognosis, and for guiding treatments. However, vascular ageing
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is not yet routinely assessed in clinical practice. A key step towards this is the development of technologies to assess vascular ageing. In this Roadmap, experts discuss several aspects of this process, including: measurement technologies; the development pipeline; clinical applications; and future research directions. The Roadmap summarises the state of the art, outlines the major challenges to overcome, and identifies potential future research directions to address these challenges.
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Keywords: ageing, arterial stiffness, blood pressure, cardiovascular, commercialisation, prevention, pulse wave velocity, Journal Article
ISSN: 0967-3334
Publisher: IOP Publishing Ltd.
Note: Publisher Copyright: © 2024 The Author(s). Published on behalf of Institute of Physics and Engineering in Medicine by IOP Publishing Ltd.
(Peer reviewed)
